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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Amlosafe TM 40 Tablet is used to treat high blood pressure (hypertension). It contains Telmisartan and Amlodipine, which widens and relaxes blood vessels. Thus, increases blood flow and lowers the chances of stroke, heart attack, and death. In some cases, it may cause side effects, such as peripheral oedema (swelling in legs and arms), common cold, back ache, diarrhoea, dizziness, drowsiness, confusion, rashes, and weakness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Aristo Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Amlosafe TM 40 Tablet

Amlosafe TM 40 Tablet belongs to the class of anti-hypertensive drugs, primarily used to treat high blood pressure (hypertension). Hypertension is a medical condition in which blood pressure is elevated persistently in the arteries. It is considered an essential risk factor for cardiovascular diseases. Amlosafe TM 40 Tablet lowers blood pressure by widening and relaxing blood vessels.

Amlosafe TM 40 Tablet is a fixed-dose combination composed of two medicines, namely, Telmisartan and Amlodipine. Telmisartan belongs to a group of drugs called angiotensin II receptor antagonists. It lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels. It is used to lower the chances of stroke, heart attack, and death. Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and increases blood flow. Altogether, it helps to lower high blood pressure, chest pain (angina), and other conditions caused by coronary artery disease.

Amlosafe TM 40 Tablet is available in the form of oral tablets. Swallow it as a whole with a glass of water. You can take Amlosafe TM 40 Tablet with or without food once a time in a day, as prescribed by the doctor. Do not crush, chew, or break it. Your doctor will decide the dosage based on your medical condition. In some cases, Amlosafe TM 40 Tablet can cause side effects, primarily peripheral oedema (swelling in legs and arms), a common cold, backache, diarrhoea, dizziness, drowsiness, confusion, rashes, and weakness. Most of these side effects of Amlosafe TM 40 Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Amlosafe TM 40 Tablet or any other medicines, please inform your doctor. Before taking Amlosafe TM 40 Tablet , let your doctor know if you have hypersensitivity like anaphylaxis (an allergic reaction which includes rashes, low pulse, and shock) or angioedema (swelling under the skin mostly swelling occurs in the face, tongue, abdomen, legs and arms). Pregnant or breastfeeding women should discontinue this Amlosafe TM 40 Tablet because it can cause injury and death to the developing fetus. Please do not stop taking Amlosafe TM 40 Tablet on your own, as it may lead to the recurrence of symptoms or worsen the condition. Do not consume alcohol with Amlosafe TM 40 Tablet as it may increase the risk of low blood pressure. Avoid potassium supplements with Amlosafe TM 40 Tablet as it may lead to high potassium levels in the blood.

Uses of Amlosafe TM 40 Tablet

Amlosafe TM 40 Tablet is used in the treatment of high blood pressure (hypertension). The detailed uses of Amlosafe TM 40 Tablet are as follows:
• Hypertension Management: Amlosafe TM 40 Tablet is primarily used to help lower high blood pressure, which can reduce the risk of heart disease and stroke.
• Heart Failure Treatment: Amlosafe TM 40 Tablet may be prescribed to patients who are experiencing heart failure symptoms, helping to improve heart function and reduce strain on the heart.
• Kidney Protection: Amlosafe TM 40 Tablet can be utilized to protect the kidneys, especially in patients with high blood pressure and diabetes, by lowering blood pressure and improving kidney function over time.
• Combination Therapy: Amlosafe TM 40 Tablet can be used in combination with other antihypertensive medications to achieve better control of blood pressure in patients requiring multiple therapies.

Directions for Use

Swallow Amlosafe TM 40 Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Amlosafe TM 40 Tablet is an anti-hypertensive drug that treats high blood pressure (hypertension). Amlosafe TM 40 Tablet lowers blood pressure by widening and relaxing blood vessels. Amlosafe TM 40 Tablet consists of two medicines, namely: Telmisartan and Amlodipine. Telmisartan belongs to a group of drugs called angiotensin II receptor antagonists. It lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels. It reduces the chances of stroke, heart attack, and death. Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and increases blood flow. Altogether, it helps to lower high blood pressure, chest pain (angina), and other conditions caused by coronary artery disease.

How Amlosafe TM 40 Tablet Works

Amlosafe TM 40 Tablet is a fixed-dose combination composed of two medicines, namely, Telmisartan and Amlodipine. Telmisartan belongs to a group of drugs called angiotensin II receptor antagonists. It lowers blood pressure and increases blood flow by preventing the narrowing of blood vessels. It is used to lower the chances of stroke, heart attack, and death. Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and increases blood flow. Altogether, it helps to lower high blood pressure, chest pain (angina), and other conditions caused by coronary artery disease.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Amlosafe TM 40 Tablet

Do not take more than the prescribed dose of Amlosafe TM 40 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Monitor your blood pressure levels regularly. If you are known to be allergic to Amlosafe TM 40 Tablet or have any kidney or liver problems or severe dehydration, please inform your doctor beforehand. Pregnant or breastfeeding women should also consult their doctor before taking it. It is advised to complete the prescribed course, even if you feel better. Complete the course strictly as suggested by the doctor, even if you feel better, to avoid disease recurrence. Avoid consumption of alcohol with Amlosafe TM 40 Tablet as it may increase the risk of low blood pressure. Avoid potassium supplements with Amlosafe TM 40 Tablet as they may lead to high potassium levels in the blood.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
TelmisartanAliskiren
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Amlosafe TM 40 Tablet:
Using Amlosafe TM 40 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Amlosafe TM 40 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
TelmisartanAliskiren
Critical
How does the drug interact with Amlosafe TM 40 Tablet:
Co-administration of Aliskiren with Amlosafe TM 40 Tablet can increase the risk of hyperkalemia (high potassium levels in the blood).

How to manage the interaction:
Taking Amlosafe TM 40 Tablet with Aliskiren can possibly lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
AmlodipineNitisinone
Severe
How does the drug interact with Amlosafe TM 40 Tablet:
Coadministration of Amlosafe TM 40 Tablet and Nitisinone may increase the blood levels and effects of Nitisinone.

How to manage the interaction:
Taking Nitisinone with Amlosafe TM 40 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineMitotane
Severe
How does the drug interact with Amlosafe TM 40 Tablet:
Using Amlosafe TM 40 Tablet and mitotane together may drastically lower Amlosafe TM 40 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Amlosafe TM 40 Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Amlosafe TM 40 Tablet:
Coadministration of Amlosafe TM 40 Tablet and Idelalisib may raise Amlosafe TM 40 Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Amlosafe TM 40 Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipineCeritinib
Severe
How does the drug interact with Amlosafe TM 40 Tablet:
Coadministration of Ceritinib together with Amlosafe TM 40 Tablet can slow heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Amlosafe TM 40 Tablet with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Amlosafe TM 40 Tablet:
Using Amlosafe TM 40 Tablet and primidone together may lower Amlosafe TM 40 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Amlosafe TM 40 Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineRifampicin
Severe
How does the drug interact with Amlosafe TM 40 Tablet:
Coadministration of Amlosafe TM 40 Tablet and rifampicin together may lower Amlosafe TM 40 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amlosafe TM 40 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineCarbamazepine
Severe
How does the drug interact with Amlosafe TM 40 Tablet:
Coadministration of Amlosafe TM 40 Tablet and carbamazepine together may significantly reduce Amlosafe TM 40 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amlosafe TM 40 Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
AmlodipineEnzalutamide
Severe
How does the drug interact with Amlosafe TM 40 Tablet:
Using a combination of Amlosafe TM 40 Tablet and enzalutamide may drastically lower Amlosafe TM 40 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Taking Amlosafe TM 40 Tablet with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+TELMISARTAN-40MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+TELMISARTAN-40MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Amlosafe TM 40 Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Amlosafe TM 40 Tablet.

Diet & Lifestyle Advise

  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Avoid chronic stress, as it can raise your blood pressure.

  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Be mindful of salt; consume no more than 2,300 mg each day.

  • Limit or avoid alcohol consumption.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

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Alcohol

Unsafe

It is unsafe to consume alcohol since alcohol consumption with Amlosafe TM 40 Tablet may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness, or headache.

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Pregnancy

Unsafe

Pregnant women should discontinue this Amlosafe TM 40 Tablet because it can cause injury and death to the developing fetus. So, Amlosafe TM 40 Tablet is not safe in pregnancy.

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Breast Feeding

Caution

There is no evidence on how Amlosafe TM 40 Tablet affects breastfeeding. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Amlosafe TM 40 Tablet .

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Driving

Caution

Amlosafe TM 40 Tablet may cause side effects like dizziness, headaches, and nausea, which can affect your ability to concentrate and drive. Hence, it is recommended not to drive until you are mentally alert.

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Liver

Caution

Inform your doctor before receiving the Amlosafe TM 40 Tablet if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current liver conditions.

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Kidney

Caution

Inform your doctor before receiving the Amlosafe TM 40 Tablet if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your current kidney conditions.

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Children

Unsafe

Amlosafe TM 40 Tablet is not recommended to use in children. Please consult the doctor if you have any concerns regarding this.

Have a query?

FAQs

Amlosafe TM 40 Tablet is used to treat high blood pressure (hypertension). It lowers the blood pressure by widening and relaxing blood vessels.

No, because your blood pressure rapidly increases when you suddenly stop this Amlosafe TM 40 Tablet . This can increase your risk of heart attack and stroke.

Pregnant women should discontinue this Amlosafe TM 40 Tablet because it can cause injury and death to the developing fetus. So, Amlosafe TM 40 Tablet is not safe in pregnancy.

There is no evidence on how Amlosafe TM 40 Tablet affects breastfeeding. Please consult your doctor before taking Amlosafe TM 40 Tablet if you are breastfeeding.

Do not stop using Amlosafe TM 40 Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.

No, Amlosafe TM 40 Tablet can cause high levels of potassium in the blood leading to hyperkalemia. Hence it is not recommended to use potassium supplements along with Amlosafe TM 40 Tablet . However, consult your doctor if you are already taking other medicines before starting Amlosafe TM 40 Tablet .

Yes, the Amlosafe TM 40 Tablet can make you feel dizzy. Dizziness usually occurs when you suddenly stand up from a lying or sitting position. Try rising slowly when you change your posture to relieve dizziness. If the side effect persists longer, please seek medical help.

Amlosafe TM 40 Tablet is generally safe to take for a long time. Remember to follow your doctor's advice/instructions.

Do not consume alcohol with Amlosafe TM 40 Tablet as it may increase the risk of low blood pressure. Avoid potassium supplements with Amlosafe TM 40 Tablet as it may lead to high potassium levels in the blood. Amlosafe TM 40 Tablet may cause side effects like dizziness, headaches, and nausea, which can affect your ability to concentrate and drive. Hence, it is recommended not to drive until you are mentally alert.

If you miss a dose of Amlosafe TM 40 Tablet take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

Stopping Amlosafe TM 40 Tablet may cause a rise in blood pressure, increasing the risk of heart attack or stroke. Therefore, do not discontinue Amlosafe TM 40 Tablet without consulting your doctor.

As hypertension is a chronic condition, you might need to take Amlosafe TM 40 Tablet for a long-term. To treat your condition effectively, keep taking Amlosafe TM 40 Tablet for the prescribed duration.

You may not notice any difference even after taking Amlosafe TM 40 Tablet as high blood pressure does not usually have any symptoms. This doesn’t mean Amlosafe TM 40 Tablet is not working. However, consult the doctor if you experience any difficulty while taking Amlosafe TM 40 Tablet .

Amlosafe TM 40 Tablet might cause erectile dysfunction in rare conditions. Consult the doctor if you cannot get or maintain an erection.

Follow a healthy diet and exercise regularly. Avoid smoking and alcohol consumption. Manage stress by doing meditation. Cut down on salt and processed foods.

Amlosafe TM 40 Tablet should be swallowed as a whole with water; do not crush or chew it.

Amlosafe TM 40 Tablet may cause side effects such as primarily peripheral oedema (swelling in legs and arms), a common cold, backache, diarrhoea, dizziness, drowsiness, confusion, rashes, and weakness. If these side effects persist or worsen, please consult your doctor.

It is advised to consult the doctor before taking other medicines with Amlosafe TM 40 Tablet to prevent any interactions or undesirable side effects.

Overdose of Amlosafe TM 40 Tablet may cause low blood pressure and slow heart rate. Seek immediate medical attention in case of an overdose of Amlosafe TM 40 Tablet .

Country of origin

India

Manufacturer/Marketer address

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
Other Info - AML0283

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