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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Amphimak 50 mg Injection 1's is used to treat severe fungal infections. It contains Amphotericin B, which kills fungi by destroying the fungal outer cell membrane. In some cases, this medicine may cause side effects such as fever, chills, nausea, vomiting, headache, muscle cramps or pain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Synonym :

LIPOSOMAL AMPHOTERICIN B

Composition :

AMPHOTERICIN B-50MG

Manufacturer/Marketer :

Biomak Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Amphimak 50 mg Injection 1's

Amphimak 50 mg Injection 1's belongs to a class of medication called 'antifungal' used to treat severe fungal infections like leishmaniasis. A fungal infection is a disease in which fungi attack the tissue and cause infection. Fungi are commonly present in nature but do not cause infections normally. However, if the person has a weak immune system, certain types of fungi may infect them. 

Amphimak 50 mg Injection 1's contains Amphotericin B, which kills fungi by destroying the fungal outer cell membrane. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.

Amphimak 50 mg Injection 1's is given by a doctor or nurse. In some cases, you may experience fever, chills, irregular heartbeat, high or low blood pressure, breathing problems, nausea, vomiting, headache, shaking, muscle cramps or pain. Most of these side effects of Amphimak 50 mg Injection 1's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Amphimak 50 mg Injection 1's or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Amphimak 50 mg Injection 1's. Amphimak 50 mg Injection 1's is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Amphimak 50 mg Injection 1's as it may affect your ability to drive. If you experience severe adverse effects such as chest pain or difficulty in breathing, or encephalopathy (a brain disease which may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help.

Uses of Amphimak 50 mg Injection 1's

Amphimak 50 mg Injection 1's is used in the treatment of Severe fungal infections. The detailed uses of Amphimak 50 mg Injection 1's are as follows:

  • Systemic fungal infections: Amphimak 50 mg Injection 1's is used to treat fungal infections including cryptococcosis (especially cryptococcal meningitis), histoplasmosis, blastomycosis, candidiasis (disseminated or invasive), coccidioidomycosis, aspergillosis, sporotrichosis.
  • Treatment of mucormycosis: Amphimak 50 mg Injection 1's is used in the treatment of mucormycosis and other rare fungal infections.

Have a query?

Directions for Use

  • Your doctor will determine the dosage and timing of Amphimak 50 mg Injection 1's based on the severity of your infection. Typically, it is administered once daily.
  • Amphimak 50 mg Injection 1's is administered by a healthcare professional in the hospital.
  • Do not self-administer it.

Medicinal Benefits

Amphimak 50 mg Injection 1's contains Amphotericin B, an antifungal used to treat severe fungal infections. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Amphimak 50 mg Injection 1's damages fungal cell membranes and kills fungi. Amphimak 50 mg Injection 1's is used to treat infections such as blood infection with candida, cryptococcus, fusarium, zygomycetes, aspergillus, coccidiodes or blastomycetes, or cryptococcal meningitis (inflammation of the brain).

How Amphimak 50 mg Injection 1's Works

Amphimak 50 mg Injection 1's contains Amphotericin B, which kills fungi by destroying the fungal outer cell membrane. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.

Storage

• Store in a cool and dry place away from sunlight.• Keep Amphimak 50 mg Injection 1's out of the sight and reach of children. • Cold chain - To be stored in cold places at 2ºC to 8ºC.

What if I have taken an overdose of Amphimak 50 mg Injection 1's

Since Amphimak 50 mg Injection 1's is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

If you are allergic to Amphotericin B or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Amphimak 50 mg Injection 1's. Amphimak 50 mg Injection 1's is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Amphimak 50 mg Injection 1's as it may affect your ability to drive. If you experience severe adverse effects such as chest pain, difficulty breathing, or encephalopathy (a brain disease that may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help. If you have diabetes, electrolyte imbalance (low magnesium or potassium levels in the blood), kidney, liver or heart problems, inform your doctor before taking Amphimak 50 mg Injection 1's.

Diet & Lifestyle Advise

  • Wash your hands regularly and keep your hands clean to prevent the spread of germs.

  • Avoid dusty activities and digging in the soil.
  • Wear shoes, a long-sleeved t-shirt and long pants while doing outdoor activities such as yard work, gardening or visiting wooded areas to protect from fungus commonly present in the environment.
  • Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

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Alcohol

Caution

The interaction of Amphimak 50 mg Injection 1's with alcohol is unknown. Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Consult your doctor

Amphimak 50 mg Injection 1's is a Category B pregnancy drug and is given to a pregnant woman if the doctor thinks the benefits outweigh the risks. Please consult your doctor if you are pregnant or planning pregnancy.

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Breast Feeding

Consult your doctor

It is unknown whether Amphimak 50 mg Injection 1's is excreted in human milk. If you are breastfeeding, inform your doctor before receiving this injection.

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Driving

Caution

Avoid driving after taking Amphimak 50 mg Injection 1's as it may affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Inform your doctor if you have a history of liver diseases/conditions before receiving Amphimak 50 mg Injection 1's.

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Kidney

Consult your doctor

Inform your doctor if you have a history of kidney diseases/conditions before receiving Amphimak 50 mg Injection 1's.

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Children

Caution

Amphimak 50 mg Injection 1's is not recommended for children below one month as the safety and effectiveness were not established.

FAQs

Amphimak 50 mg Injection 1's is used to treat severe fungal infections like leishmaniasis.

Amphimak 50 mg Injection 1's contains Amphotericin B, an antifungal that works by damaging fungal cell membranes, thereby killing fungi.

You are not recommended to take Amphimak 50 mg Injection 1's with furosemide as co-administration of these medicines may increase the risk of hypokalaemia (low potassium levels in the blood), and in severe cases, it may lead to paralysis, muscle weakness, irregular heart rhythm, difficulty in breathing or swallowing. However, please consult your doctor before taking Amphimak 50 mg Injection 1's with other medicines.

Amphimak 50 mg Injection 1's may cause blue lips and skin, probably during infusion or in the initial 2 days of treatment. However, your doctor or nurse may arrange certain simple treatments to control such adverse effects.

Yes, a test dose of Amphimak 50 mg Injection 1's may be given in smaller amounts before starting the treatment to check if you are sensitive to any of the ingredients.

You are recommended to use Amphimak 50 mg Injection 1's for as long as your doctor has prescribed it. However, the usual treatment is for a minimum of 14 days. Please consult a doctor if you experience any difficulty while taking Amphimak 50 mg Injection 1's.

Amphimak 50 mg Injection 1's is not used to treat viral infections. Amphimak 50 mg Injection 1's is an antifungal that kills fungi and is used to treat severe fungal infections.

Amphimak 50 mg Injection 1's is an antifungal medication used to treat severe fungal infections like leishmaniasis. It kills fungi by destroying the fungal outer cell membrane.

Amphimak 50 mg Injection 1's will be administered intravenously by a healthcare professional; do not self-administer.

Amphimak 50 mg Injection 1's is fungicidal in nature, it works by killing the infection-causing fungus.

Inform the doctor if you are allergic to any of the components in Amphimak 50 mg Injection 1's or if you experience allergic reactions during treatment with Amphimak 50 mg Injection 1's. Let the doctor know if you have kidney problems, diabetes, or if you are taking any other medicines.

Amphimak 50 mg Injection 1's is an antifungal medication used to treat severe fungal infections like leishmaniasis

Amphimak 50 mg Injection 1's may cause side effects like fever, chills, nausea, vomiting, headache, muscle cramps or pain. Most of these side effects of Amphimak 50 mg Injection 1's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

PLOT NO 154, SECTOR-68 IMT Faridabad, Haryana 121004 IN.
Other Info - AMP0289

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