Apnicaf Oral Solution 3 ml

Selected Pack Size:3 ml

3 ml
₹723.6
(₹241.2 / 1 ml)
Out of stock
1.5 ml
₹348.3
(₹232.2 / 1 ml)
Out of stock

₹804

(Inclusive of all Taxes)

₹120.6 Cashback (15%)

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Apnicaf Oral Solution 3 ml belongs to the class of methylxanthine drugs used in the treatment of primary apnea of premature newborns/neonates. This medicine helps regulate the mean respiratory rate and tidal volume, and improves pulmonary blood flow, by stimulating the respiratory centre, sensitising it to hypercapnia. Some of the common side effects include fast heartbeat, irregular heartbeat and hyperglycaemia. It is a paediatric medication and helps avoid using in adult population.

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About Apnicaf Oral Solution 3 ml

Apnicaf Oral Solution 3 ml belongs to a group of medicines known as methylxanthines. It is used to treat primary apnoea of premature newborns (interrupted breathing in premature babies). Apnea is a condition where breathing interrupts and causes abnormal heart rate and oxygen saturation alterations. It is a common occurrence, particularly in premature infants.

Apnicaf Oral Solution 3 ml contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. It works in three different ways. Firstly, it is the adenosine receptor antagonist; secondly, it is a phosphodiesterase inhibitor. And thirdly, it is an active intracellular calcium mobiliser. Collectively Caffeine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby Apnicaf Oral Solution 3 ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, decreases carbon dioxide sensitivity and enhances diaphragmatic function and breathing pattern.

Apnicaf Oral Solution 3 ml should be used as prescribed by your doctor. Your doctor will determine the suitable dosage based on your infant's medical conditions. In some cases, Apnicaf Oral Solution 3 ml can cause side effects like tachycardia (fast heartbeat), arrhythmia (irregular heartbeat) and hyperglycaemia (increased sugar in blood or serum). These side effects are not prevalent and vary from person to person. Consult your doctor if these symptoms continue or worsen. They may be able to recommend strategies to avoid or minimise certain side effects.

Inform your doctor about the complete medical history of your infant. If you are nursing your infant is being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since Caffeine passes into breast milk. This medication should be used with caution in infants with impaired hepatic or renal function. Before fixing the dose, your doctor may assess baseline serum caffeine levels in children born to caffeine-consuming mothers.

Uses of Apnicaf Oral Solution 3 ml

Treatment of Primary apnea of premature newborns/neonates

Directions for Use

• Apnicaf Oral Solution 3 ml can be given with or without food as advised by your doctor.• Follow your doctor's instructions regarding the dosage and duration of the medication.• Apnicaf Oral Solution 3 ml is given by mouth or through a feeding tube as directed by the doctor.• Measure the prescribed dose using a suitable syringe and administer it as directed by your doctor.

Medicinal Benefits

Apnicaf Oral Solution 3 ml contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. It works in three different ways. Firstly, it is the adenosine receptor antagonist; secondly, it is a phosphodiesterase inhibitor. And thirdly, it is an active intracellular calcium mobiliser. Collectively Caffeine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby Apnicaf Oral Solution 3 ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, decreases carbon dioxide sensitivity and enhances diaphragmatic function and breathing pattern.

How Apnicaf Oral Solution 3 ml Works

Apnicaf Oral Solution 3 ml contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. It works in three different ways. Firstly, it is the adenosine receptor antagonist; secondly, it is a phosphodiesterase inhibitor. And thirdly, it is an active intracellular calcium mobiliser. Collectively Caffeine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby Apnicaf Oral Solution 3 ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, decreases carbon dioxide sensitivity and enhances diaphragmatic function and breathing pattern.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Apnicaf Oral Solution 3 ml out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ÂºC to 25ÂºC or below 30ÂºC.

What if I have taken an overdose of Apnicaf Oral Solution 3 ml

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include anxiety, stomach pain, confusion, agitation, frequent urination, irregular/fast heartbeat, ringing in the ears, muscle twitching, seizures, and trouble sleeping. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor about your infant's medical history. If you are breastfeeding and your infant is being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since caffeine passes into breast milk. Apnicaf Oral Solution 3 ml should only be used in a neonatal intensive care unit where adequate patient surveillance and monitoring facilities are available. Treatment should begin under the supervision of a neonatologist with experience in neonatal intensive care. This medication should be used with caution in infants with impaired liver or kidney function.

Habit Forming

No

Therapeutic Class

ALTERNATIVE MEDICINE

Apnicaf Oral Solution 3 ml Substitute

Capnea Solution 1ml

by Others

₹247.50per tablet

CAFIRATE SOLUTION 1.5ML

by Others

₹371.30per tablet

Alcohol

Caution

Apnicaf Oral Solution 3 ml is intended to use in premature newborns/neonates.

Pregnancy

Caution

Apnicaf Oral Solution 3 ml is recommended to be used only in infants.

Breast Feeding

Caution

Apnicaf Oral Solution 3 ml is intended for use in newborns/neonates only. If your infant is being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since caffeine passes into breast milk.

Driving

Caution

Apnicaf Oral Solution 3 ml is intended to use in premature newborns/neonates.

Liver

Caution

Apnicaf Oral Solution 3 ml should be used with caution in infants with impaired hepatic or liver function.

Kidney

Caution

Apnicaf Oral Solution 3 ml should be used with caution in infants with impaired renal or kidney function.

Children

Caution

Apnicaf Oral Solution 3 ml is intended to use in premature newborns/neonates.

Have a query?

FAQs

What is the use of Apnicaf Oral Solution 3 ml?

Apnicaf Oral Solution 3 ml belongs to a group of medicines known as methylxanthines. It is used to treat primary apnoea of premature newborns (interrupted breathing in premature babies).

How does Apnicaf Oral Solution 3 ml work?

Apnicaf Oral Solution 3 ml contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. It works in three different ways. Firstly, it is the adenosine receptor antagonist; secondly, it is a phosphodiesterase inhibitor. And thirdly, it is an active intracellular calcium mobiliser. Collectively Caffeine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby Apnicaf Oral Solution 3 ml effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, decreases carbon dioxide sensitivity and enhances diaphragmatic function and breathing pattern.

Does Apnicaf Oral Solution 3 ml ideal for treating sleep disorders in adults?

No, it is intended to treat primary apnoea of premature newborns/neonates.

What are the prerequisites for fixing the dose?

The dosage is determined by your baby's weight, medical problems, and responsiveness to therapy. Before determining the dose, it is also necessary to establish the baseline serum caffeine levels in children born to caffeine-consuming mothers.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India

Other Info - APN0015

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:24 AM IST

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Apnicaf Oral Solution 3 ml

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Apnicaf Oral Solution 3 ml Substitute

Capnea Solution 1ml

CAFIRATE SOLUTION 1.5ML

Capnea Solution 1ml

CAFIRATE SOLUTION 1.5ML

FAQs

What is the use of Apnicaf Oral Solution 3 ml?

How does Apnicaf Oral Solution 3 ml work?

Does Apnicaf Oral Solution 3 ml ideal for treating sleep disorders in adults?

What are the prerequisites for fixing the dose?

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Author Details

Reference