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  3. Appitral 40 Tablet 10's

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Appitral 40 Tablet 10's, Pack of 10 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Appitral 40 Tablet 10's is used as a symptomatic treatment in patients with breast cancer and endometrial cancer. It contains Megestrol, which works similarly to the female hormone progesterone. It interferes with the production or action of hormones involved in cancer growth. This effect helps to slow down the progression of cancer and reduce the symptoms associated with cancer.

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Composition :

MEGESTROL-40MG

Manufacturer/Marketer :

EVERVITAL LIFESCIENCES

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Appitral 40 Tablet 10's

Appitral 40 Tablet 10's is used as a symptomatic treatment in patients with breast cancer and endometrial cancer. Breast cancer develops in the breast cells and is characterised by a lump in the breast, a change in the shape of the nipple or breast, and bloody discharge from the nipples.

Appitral 40 Tablet 10's contains ‘Megestrol’, which interferes with the production or action of hormones involved in cancer growth. This effect helps to slow down the progression of cancer and reduce the symptoms associated with cancer.

Common side effects of Appitral 40 Tablet 10's include increased appetite, weight gain, shortness of breath, hot flushes, high blood pressure, increased blood sugar levels, a rounded face, constipation, and swelling of a vein due to a blood clot. If any of these side effects persist or get worse, inform your doctor immediately.

Do not take Appitral 40 Tablet 10's if you are allergic to Megestrol or any of its contents. Before taking Appitral 40 Tablet 10's, inform your doctor if you have severe liver problems, a history of thrombophlebitis (blood clots), stroke, adrenal gland disorder, or diabetes. Appitral 40 Tablet 10's is not recommended for children, pregnant women, and breastfeeding mothers.

Uses of Appitral 40 Tablet 10's

Appitral 40 Tablet 10's is used in the treatment of breast cancer and endometrial cancer. The detailed uses of Appitral 40 Tablet 10's are as follows:

  • Breast cancer treatment: Appitral 40 Tablet 10's is used to treat breast cancer by targeting hormone-sensitive tumours to slow or stop cancer growth, reducing tumour size, and alleviating symptoms.
  • Endometrial cancer management: Appitral 40 Tablet 10's helps to manage endometrial cancer progression in the lining of the uterus, slowing disease advancement and improving quality of life.

Have a query?

Directions for Use

  • Take Appitral 40 Tablet 10's with or without food as advised by your doctor.
  • Adhere to your doctor’s guidance regarding the dosage and timing of this medication for optimal effectiveness.
  • Swallow Appitral 40 Tablet 10's as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Appitral 40 Tablet 10's contains Megestrol, which is used to treat breast and endometrial cancer.
  • It acts by interfering with the production of hormones that cause cancer's development.
  • It helps to reduce cancer symptoms effectively.
  • It can also be used to treat loss of appetite in patients with HIV/AIDS.

How Appitral 40 Tablet 10's Works

Appitral 40 Tablet 10's contains Megestrol, a Progestogen. Megestrol may work by affecting certain hormones. This may increase appetite, helping with weight loss.

Storage

• Store in a cool and dry place away from sunlight.• Keep Appitral 40 Tablet 10's out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Appitral 40 Tablet 10's

Do not take more than the prescribed dose of Appitral 40 Tablet 10's as it may cause any side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Appitral 40 Tablet 10's increases the risk of blood clots, so it should be used cautiously in patients with a history of thrombophlebitis.
  • Also, if you notice impaired coordination, difficulty speaking, pain in the groin, pain in the arm or leg (especially in the calf of the leg), shortness of breath, general weakness, headache, and dizziness, inform your doctor immediately as it may be a sign of blood clot.
  • Appitral 40 Tablet 10's is not recommended for use in pregnancy.
  • Use a reliable contraceptive method to prevent pregnancy while using this medicine.
  • You may also need to take a pregnancy test before using this medicine.
  • Appitral 40 Tablet 10's contains lactose, so inform your doctor if you have an intolerance to any sugars.

Drug-Drug Interactions

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MegestrolDofetilide
Severe
MegestrolThalidomide
Severe

Drug-Drug Interactions

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MegestrolDofetilide
Severe
How does the drug interact with Appitral 40 Tablet:
Co-administration of Appitral 40 Tablet and Dofetilide can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions or electrolyte disturbances, you may be at higher risk.

How to manage the interaction:
Co-administration of Appitral 40 Tablet with Dofetilide can possibly result in an interaction, but it can be taken if a doctor has advised it. If you're having any of these symptoms like dizziness, fainting, lightheadedness, lack of breath, chest discomfort, or palpitations, consult a doctor. Do not stop using any medications without a doctor's advice.
MegestrolThalidomide
Severe
How does the drug interact with Appitral 40 Tablet:
Taking Thalidomide together with Appitral 40 Tablet may increase the risk of blood clots.

How to manage the interaction:
Although taking thalidomide and Appitral 40 Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet. Avoid fast food, fried food, processed meats, refined carbs, and added sugar.
  • Drink plenty of fluids and eat fibre-rich food to prevent constipation.
  • Manage your weight. Shed excess weight by exercising regularly if you are obese or overweight.
  • Wear loose, layered clothing at night, especially in warm weather. This prevents hot flushes.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

PROGESTINS

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Alcohol

Caution

Alcohol consumption may increase the risk of side effects and worsen the disease. So, avoid alcohol consumption while using this medicine.

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Pregnancy

Unsafe

Appitral 40 Tablet 10's should not be used in pregnant women as it may cause birth defects in the unborn baby. Women who are of childbearing potential should obtain a negative pregnancy test before using this medicine.

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Breast Feeding

Unsafe

Appitral 40 Tablet 10's is not recommended for use in breastfeeding as it may pass into breastmilk and harm your infant.

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Driving

Safe if prescribed

Appitral 40 Tablet 10's may not affect your ability to drive.

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Liver

Caution

Appitral 40 Tablet 10's should be used with caution if you have liver disease. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Appitral 40 Tablet 10's should be used with caution if you have kidney disease. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Appitral 40 Tablet 10's is not recommended for use in children below 12 years of age.

FAQs

Appitral 40 Tablet 10's is used for the treatment of Breast cancer and Endometrial cancer.

Appitral 40 Tablet 10's contains Megestrol, which works similarly to the female hormone progesterone. It interferes with the production or action of hormones involved in cancer growth. This effect helps to slow down the progression of cancer and reduce the symptoms associated with cancer.

Appitral 40 Tablet 10's may increase appetite and cause weight gain. You may gain weight, especially in the waist and the upper back. This effect usually decreases after discontinuing the treatment. However, opt for a healthy diet, exercise regularly, and maintain a normal weight while using this medicine.

Appitral 40 Tablet 10's may not affect fertility but may disrupt the menstrual cycle (periods). Though this medicine affects periods, you should take reliable contraceptive measures while using Appitral 40 Tablet 10's to prevent pregnancy as it may cause harmful effects to the unborn baby.

Appitral 40 Tablet 10's may increase blood glucose levels, so inform your doctor that you have diabetes before taking this medicine. If prescribed, you should monitor blood glucose levels regularly during the treatment.

Appitral 40 Tablet 10's is not a contraceptive and doesn't help to prevent pregnancy. It would be best to discuss the possible benefits and risks associated with this medicine with your doctor before using it.

It is recommended that you complete the course of Appitral 40 Tablet 10's even if you feel better. To treat your condition effectively, continue taking Appitral 40 Tablet 10's for as long as your doctor has prescribed it.

If you miss a dose of Appitral 40 Tablet 10's, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular schedule. Do not take twice the dose to make up for a missed dose.

Take Appitral 40 Tablet 10's at around the same time(s) every day. Follow the directions on your prescription label or as directed by the physician.

Appitral 40 Tablet 10's may disrupt the menstrual cycle (periods). If you experience any discomfort, please consult a doctor for an appropriate treatment plan.

Appitral 40 Tablet 10's is a hormonal therapy drug used to treat breast and womb cancer.

No, it is not recommended to use while pregnant. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking megestrol, call your doctor immediately. Megestrol may harm the foetus.

Appitral 40 Tablet 10's may interfere with women's normal menstrual cycle (period). However, it would be best not to assume you cannot become pregnant. Seek medical advice from your healthcare personnel if you are pregnant and plan to become pregnant.

No, do not refrigerate. It should be stored in a cool and dry place away from sunlight.

No, there is no clinically proven indication to treat hot flushes with Appitral 40 Tablet 10's.

The common side-effects of Appitral 40 Tablet 10's are an increase in appetite, weight gain, shortness of breath, hot flushes (reddening of the face and neck), high blood pressure, increased blood sugar levels, a rounded face, constipation, and swelling of a vein due to a blood clot. If any of these side effects persist or get worse, inform your doctor immediately.

Country of origin

India

Manufacturer/Marketer address

403 Vishala Empire Sp Ring Road Near Ranasan Toll Plaza Naroda Murthia Ahmedabad Ahmedabad Gj 382330 In.
Other Info - APP0233

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Nov 19, 2025 | 1:23 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.11135.pdf
  2. https://www.drugs.com/mtm/megestrol.html

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