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Apronin 500000IU Injection belongs to the group of medicines called anti-fibrinolytic agents used to reduce bleeding during and after heart surgery. It is also used to lower the need for blood transfusion during and after heart surgery.
Apronin 500000IU Injection contains aprotinin that prevents bleeding by inhibiting the activation of coagulants.
Apronin 500000IU Injection will be administered by a healthcare professional; do not self-administer. In some cases, Apronin 500000IU Injection may cause chest pain, stomach upset, fast heartbeat and injection site reactions. You are advised to talk to the doctor if you experience any side effects.
Consult the doctor if you are pregnant or breastfeeding. Apronin 500000IU Injection is not recommended for children below 18 years as the safety and effectiveness have not been established. Keep your doctor informed about your health condition and medications to rule out any unpleasant side effects/interactions.
Apronin 500000IU Injection is used to reduce the risk of bleeding during and after surgery. The detailed uses of Apronin 500000IU Injection are as follows:
Apronin 500000IU Injection contains aprotinin that belongs to the group of medicines called anti-fibrinolytic agents used to reduce bleeding during and after heart surgery. It also lowers the need for blood transfusion during and after heart surgery. Apronin 500000IU Injection inhibits the activation of coagulants. Thereby, Apronin 500000IU Injection prevents bleeding.
Consult your doctor
It is not known if Apronin 500000IU Injection interacts with alcohol. Please consult your doctor.
Caution
If you are pregnant, inform your doctor before receiving Apronin 500000IU Injection. The doctor will prescribe the medicine only if the benefits outweigh the risks.
Caution
If you are a nursing mother, inform your doctor before receiving Apronin 500000IU Injection. The doctor will prescribe the medicine only if the benefits outweigh the risks.
Not applicable
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Consult your doctor
If you have a history of liver disease, inform your doctor before receiving Apronin 500000IU Injection.
Caution
If you have a history of kidney disease, inform your doctor before receiving Apronin 500000IU Injection. It should be used only in patients with kidney problems if the doctor/surgeon thinks the benefits outweigh the risks.
Unsafe
Apronin 500000IU Injection is not recommended for children below 18 years as the safety and efficacy have not been established.
Consult your doctor
Please consult your doctor before receiving Apronin 500000IU Injection if you have pre-existing heart problems. Your doctor will prescribe Apronin 500000IU Injection if the benefits outweigh the risks.
Consult your doctor
Please consult a doctor before administering Apronin 500000IU Injection to geriatric patients. Your doctor will prescribe Apronin 500000IU Injection if the benefits outweigh the risks.
Have a query?
Do not use Apronin 500000IU Injection if you are allergic to any of its components or if a positive aprotinin-specific IgG antibody test is available, indicating an increased risk of an allergic reaction to aprotinin. Inform the doctor if you have kidney problems or have/suspect you have received aprotinin or aprotinin-containing fibrin sealants in the last 12 months. Consult the doctor if you are pregnant or breastfeeding. Let the doctor know if you have any health condition or if you are taking any medications, including herbal products or vitamin/mineral supplements.
Drug-Drug Interactions: Inform the doctor if you take medicines used to dissolve blood clots (streptokinase, urokinase, alteplase) or antibiotics (aminoglycosides).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform the doctor if you have kidney problems.
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Apronin 500000IU Injection is used to reduce the risk of bleeding during and after surgery.
Apronin 500000IU Injection works by inhibiting the activation of coagulants. Thereby, Apronin 500000IU Injection prevents bleeding.
Apronin 500000IU Injection is prescribed when the doctor has decided that you will benefit from the treatment because you are at an increased risk of major blood loss as you will undergo a heart bypass operation using the heart-lung machine (circulation outside the body). Your doctor will prescribe Apronin 500000IU Injection only after careful consideration of the benefits and risks.
Apronin 500000IU Injection may raise the risk of kidney problems, and there may be a need for dialysis after surgery. This risk might be higher in patients with existing kidney problems or in people taking medicines that harm the kidneys, such as gentamicin. Therefore, inform the doctor if you have kidney problems.
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