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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Aprovel 150mg Tablet is used for the treatment of hypertension (high blood pressure) in adults. Additionally, it is used to reduce the risk of heart attack or stroke in adults. It contains Irbesartan, which widens and relaxes blood vessels. Thus, lowers high blood pressure. In some cases, you may experience nausea, vomiting, fatigue, and orthostatic hypotension. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Composition :

IRBESARTAN-150MG

Manufacturer/Marketer :

Sanofi India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Aprovel 150mg Tablet

Aprovel 150mg Tablet belongs to a group of medicines known as angiotensin II receptor blockers indicated for the treatment of hypertension (high blood pressure) in adults. Additionally, Aprovel 150mg Tablet is used to reduce the risk of heart attack or stroke in adults. Hypertension is a medical condition in which the blood pressure is elevated persistently in the arteries without any known cause. On the other hand, heart attack or stroke occurs due to blocked blood flow to the heart or brain, respectively.

Aprovel 150mg Tablet works by blocking the action of a hormone called angiotensin II in the body, which causes the narrowing of blood vessels, leading to high blood pressure. Thereby, Aprovel 150mg Tablet widens and relaxes blood vessels, lowering high blood pressure.

You can take Aprovel 150mg Tablet irrespective of food and swallow it whole with a glass of water. Do not crush, chew, or break it. Your doctor will let you how often you should take your tablets based on your medical condition. In some cases, you may experience nausea, vomiting, fatigue, and orthostatic hypotension. Most of these side effects of Aprovel 150mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Aprovel 150mg Tablet is not for pregnant women as its use during your pregnancy can cause injury and even death to your unborn baby. It is not known whether Aprovel 150mg Tablet passes into your breast milk or not. Your doctor will decide if you will take Aprovel 150mg Tablet while using Aprovel 150mg Tablet and breastfeeding together. Prolonged intake of Aprovel 150mg Tablet may cause high potassium in the blood (hyperkalemia). Avoid intake of potassium supplements with Aprovel 150mg Tablet as it may lead to high potassium levels in the blood, so the doctor may ask you to have a regular check of your potassium level. Do not consume alcohol with Aprovel 150mg Tablet as it may increase the risk of low blood pressure. Taking Aprovel 150mg Tablet with painkillers (like aspirin and ibuprofen) can increase the risk of kidney problems and reduce the efficiency of Aprovel 150mg Tablet.

Uses of Aprovel 150mg Tablet

Treatment of Hypertension, Heart failure, Prevents heart attack & heart stroke.

Directions for Use

Swallow Aprovel 150mg Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Aprovel 150mg Tablet is used to treat high blood pressure and reduce the risk of heart attack or stroke. Aprovel 150mg Tablet is an angiotensin II receptor blocker that decreases high blood pressure by widening and relaxing the blood vessels by blocks the action of a hormone called angiotensin II in the body which causes the narrowing of blood vessels leading to high blood pressure.

How Aprovel 150mg Tablet Works

Aprovel 150mg Tablet works by blocking the action of a hormone called angiotensin II in the body, which causes the narrowing of blood vessels, leading to high blood pressure. Thereby, Aprovel 150mg Tablet widens and relaxes blood vessels, lowering high blood pressure.

Storage

Store in a cool and dry place away from sunlight
Side effects of Aprovel 150mg Tablet
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Get plenty of fresh air.
  • Take regular sips of a cold drink.
  • Take ginger containing foods like ginger tea and ginger biscuits.
  • Do not take heavy meals at a time, take small and frequent meals.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of Aprovel 150mg Tablet

Do not take more than the prescribed dose of Aprovel 150mg Tablet as it may cause overdose. The symptoms of overdose include low blood pressure, fast or slow heart rate. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Aprovel 150mg Tablet is not recommended for people with impaired kidney function, diabetes or severe liver problems. Aprovel 150mg Tablet may increase the risk of low blood pressure when taken with alcohol. Aprovel 150mg Tablet may cause tiredness or dizziness in some people. Make sure you are not affected before driving. Breastfeeding women are advised to consult a doctor before taking Aprovel 150mg Tablet. Avoid intake of potassium supplements with Aprovel 150mg Tablet as it may lead to high potassium levels in the blood, so the doctor may ask you to have a regular check of your potassium level. Do not consume alcohol with Aprovel 150mg Tablet as it may increase the risk of low blood pressure. Taking Aprovel 150mg Tablet with painkillers (like aspirin and ibuprofen) can increase the risk of kidney problems and reduce the efficiency of Aprovel 150mg Tablet.

Drug-Drug Interactions

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IrbesartanTrimethoprim
Severe
IrbesartanLisinopril
Severe

Drug-Drug Interactions

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IrbesartanTrimethoprim
Severe
How does the drug interact with Aprovel 150mg Tablet:
Taking Aprovel 150mg Tablet with Trimethoprim may increase potassium levels in the blood and kidney problems.

How to manage the interaction:
Although taking Aprovel 150mg Tablet with Trimethoprim together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult your doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
IrbesartanLisinopril
Severe
How does the drug interact with Aprovel 150mg Tablet:
Taking Aprovel 150mg Tablet with Lisinopril may increase potassium levels in the blood.

How to manage the interaction:
Although taking Aprovel 150mg Tablet with Lisinopril together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
IrbesartanSpironolactone
Severe
How does the drug interact with Aprovel 150mg Tablet:
Taking Aprovel 150mg Tablet with Spironolactone may increase potassium levels in the blood, which may lead to side effects.

How to manage the interaction:
Taking Aprovel 150mg Tablet with Spironolactone can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctors advise.
IrbesartanPotassium chloride
Severe
How does the drug interact with Aprovel 150mg Tablet:
Taking Aprovel 150mg Tablet with Potassium chloride may increase potassium levels in the blood.

How to manage the interaction:
Although taking Aprovel 150mg Tablet with Potassium chloride together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
IrbesartanTriamterene
Severe
How does the drug interact with Aprovel 150mg Tablet:
Taking Aprovel 150mg Tablet with Triamterene may increase potassium levels in the blood. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis and heart problems.

How to manage the interaction:
Although taking Aprovel 150mg Tablet with Triamterene together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
IrbesartanRamipril
Severe
How does the drug interact with Aprovel 150mg Tablet:
Taking Ramipril together with Aprovel 150mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Aprovel 150mg Tablet with Ramipril together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
Irbesartanpotassium phosphate
Severe
How does the drug interact with Aprovel 150mg Tablet:
Taking Aprovel 150mg Tablet with Potassium phosphate may increase potassium levels in the blood. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis and heart problems.

How to manage the interaction:
Although taking Aprovel 150mg Tablet with potassium phosphate together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, slow or irregular heartbeat. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and salt substitutes that include potassium during this treatment. Do not discontinue any medications without a doctor's advice.
IrbesartanLofexidine
Severe
How does the drug interact with Aprovel 150mg Tablet:
Co-administration of Aprovel 150mg Tablet with Lofexidine can decrease the low blood pressure, which may lead to side effects.

How to manage the interaction:
Taking Aprovel 150mg Tablet with Lofexidine can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of these signs - slow heart rate, headache, feeling dizzy or lightheaded, or fainting - make sure to contact a doctor right away. Avoid activities requiring mental focus like driving, operating dangerous equipment. Be careful while getting up from a sitting or lying position. Do not discontinue any medications without consulting a doctor.
IrbesartanMoexipril
Severe
How does the drug interact with Aprovel 150mg Tablet:
Taking Aprovel 150mg Tablet with Moexipril may cause low blood pressure, kidney function impairment, and increased potassium levels in the blood.

How to manage the interaction:
Although taking Aprovel 150mg Tablet with Moexipril together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
IrbesartanEnalapril
Severe
How does the drug interact with Aprovel 150mg Tablet:
Due to additive or synergistic effects, coadministration of enalapril with Aprovel 150mg Tablet may raise the risk of hyperkalemia, hypotension, syncope, and renal failure. In severe cases, hyperkalemia can lead to muscle paralysis,kidney damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Enalapril together with Aprovel 150mg Tablet may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

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IRBESARTAN-150MGPotassium rich foods
Moderate

Drug-Food Interactions

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IRBESARTAN-150MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consuming potassium-containing substances during treatment with Aprovel 150mg Tablet can lead to high potassium levels which may result in side effects like weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs. Avoid potassium-containing salt substitutes and over-the-counter potassium supplements during Aprovel 150mg Tablet therapy.

Diet & Lifestyle Advise

  • Maintain a low-salt diet and minimize eating processed foods, as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
  • Regular exercise, such as cycling, walking, jogging, dancing, or swimming, should be done for a minimum of 30 minutes daily.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress by changing your expectations, readjusting your reactions to certain situations, and making time for yourself to do activities that you enjoy.
  • Maintain a diet that is rich in fruits, vegetables, whole grains and low-fat dairy products.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Aprovel 150mg Tablet Substitute

Substitutes safety advice
  • Irovel 150 Tablet 10's

    by Others

    17.55per tablet
  • Iberset 150 Tablet

    by Others

    16.20per tablet
  • Insat 150 Tablet 10's

    by Others

    7.33per tablet
  • Irbenol 150mg Tablet

    by Others

    8.10per tablet
  • Irbemax 150mg Tablet

    by Others

    15.75per tablet
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Alcohol

Caution

Not recommended. Aprovel 150mg Tablet and alcohol together result in an abnormal decrease in blood pressure levels, thus strictly not to be taken together.

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Pregnancy

Unsafe

Not recommended in pregnant patients. Aprovel 150mg Tablet is harmful to an unborn baby, especially in the first 3 months of pregnancy. Aprovel 150mg Tablet is to be replaced with any other blood pressure-lowering drug on doctor consultation.

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Breast Feeding

Caution

Not recommended in breastfeeding patients. Enough data is not available on the usage of Aprovel 150mg Tablet in breastfeeding mothers; thus, it is replaced with any alternative blood pressure-lowering agents in doctors' consultations.

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Driving

Safe if prescribed

Aprovel 150mg Tablet is unlikely to affect your ability to drive or use heavy machines. However, occasionally, dizziness or slowness of movements may occur during the treatment of high blood pressure. If you experience these, talk to your doctor before attempting such activities.

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Liver

Caution

Aprovel 150mg Tablet has been found to affect liver function in certain cases; thus, patients with liver problems should discuss with their doctor for proper guidance regarding treatment with this medication.

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Kidney

Caution

Aprovel 150mg Tablet is not advised for patients with kidney disease as there have been cases of harmful interactions between kidney patients and Aprovel 150mg Tablet. Patients are strictly advised to consult and discuss this medication with their doctors before taking it.

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Children

Safe if prescribed

It is safe to give to children under 12 years of age. No harmful interaction has been reported in patients under 12 years of age, yet doctor's consultation is advised.

Have a query?

FAQs

Aprovel 150mg Tablet is indicated for the treatment of hypertension (high blood pressure) in adults. Additionally, it is used to reduce the risk of heart attack or stroke in adults.

Aprovel 150mg Tablet may increase potassium levels in the blood (hyperkalemia). Therefore, it is recommended to avoid intake of potassium supplements and foods that are rich in potassium like coconut water, bananas and broccoli.

Only on doctors consultation, a patient can take Aprovel 150mg Tablet with metformin which has been found to have a beneficial effect on kidneys in a diabetic patient with hypertension.

Not recommended in overweight patients as per studies conducted by researchers,Aprovel 150mg Tablet causes weight gain in normal individuals and thus contraindicated in overweight patients.

Take the missed dose as soon as possible. if it has been too late then a patient is advised to jump to the next dose without attempting double dose to make up for the missed dose.

Absolutely safe to be used in patients with stomach ulcers as there has been no harmful interaction between Aprovel 150mg Tablet and peptic ulcers except occasional nausea. Recently it has been found to have a protective role against stomach ulcers yet not approved for stomach diseases yet.

Country of origin

India

Manufacturer/Marketer address

207 Signature - 1 2nd floor Near Divya Bhaskar Press, Makarba Railway Crossing, S. G. Highway Makarba, Ahmedabad - 380051
Other Info - AP66460

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