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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Arsenam 10 Injection 10 ml is used to treat acute promyelocytic leukaemia. Acute promyelocytic leukaemia is a type of cancer in which there are too many immature blood cells in the blood and bone marrow. It contains Arsenic trioxide, which works by interfering with the growth of cancer cells and slowing their growth and spread in the body. Arsenam 10 Injection 10 ml may cause side effects such as fatigue, pain, fever, headache, nausea, vomiting, and diarrhoea.

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Manufacturer/Marketer :

GLS Pharma Ltd

Consume Type :

Parenteral

Expires on or after :

Return Policy :

Not Returnable

About Arsenam 10 Injection 10 ml

Arsenam 10 Injection 10 ml belongs to the group of medicines called anti-neoplastic agents used to treat acute promyelocytic leukaemia (APL). Acute promyelocytic leukaemia is a type of cancer in which there are too many immature blood cells in the blood and bone marrow.

Arsenam 10 Injection 10 ml contains Arsenic trioxide, which works by interfering with the growth of cancer cells and slowing their growth and spread in the body.

Arsenam 10 Injection 10 ml may cause side effects such as fatigue, pain, fever, headache, nausea, vomiting, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not use Arsenam 10 Injection 10 ml if you are pregnant or breastfeeding. This medicine may not be recommended for children as safety and effectiveness have not been established. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Arsenam 10 Injection 10 ml

Arsenam 10 Injection 10 ml used in the treatment of Acute promyelocytic leukaemia. The detailed use of Arsenam 10 Injection 10 ml is as follows:

  • Treatment of Acute promyelocytic leukaemia: Arsenam 10 Injection 10 ml provides relief in Acute Promyelocytic Leukemia by interfering with the growth of cancer cells, thereby slowing their growth and spread in the body, providing relief to patients.

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Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Arsenam 10 Injection 10 ml should be given under the guidance of a doctor experienced in treating patients with acute leukemia.
  • Do not self-administer it.

Key Benefits

Arsenam 10 Injection 10 ml belongs to the group of medicines called anti-neoplastic agents used to treat acute promyelocytic leukaemia (APL). Arsenam 10 Injection 10 ml contains Arsenic trioxide, which works by interfering with the growth of cancer cells and slowing their growth and spread in the body.

How Arsenam 10 Injection 10 ml Works

Arsenam 10 Injection 10 ml contains Arsenic trioxide, which works by interfering with the growth of cancer cells and slowing their growth and spread in the body.

Storage

Store in a cool and dry place away from sunlight
Side effects of Arsenam 10 Injection 10 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • To increase your body temperature, take a soothing shower or soak in a warm bath.
  • Avoid cold foods and beverages since they can cause your body temperature to drop even more.
  • Stay indoors when it's cold, especially if you're feeling unwell.
  • Consult your doctor if your chills continue, get worse, or are accompanied by other unusual symptoms.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.

What if I have taken an overdose of Arsenam 10 Injection 10 ml

As Arsenam 10 Injection 10 ml is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not receive Arsenam 10 Injection 10 ml if you are allergic to any of its components. Inform the doctor if you have kidney or liver diseases. Seek immediate medical attention if you experience symptoms of low APL differentiation syndrome (fever, weight gain, shortness of breath, laboured breathing, chest pain, or cough), QT prolongation/heart rhythm problems or encephalopathy (confusion, loss of consciousness, seizures, speech changes, problems with coordination, balance, or walking, or visual changes such as decreased visual perception, reading problems, or double vision). Consult the doctor if you or your partner becomes pregnant while on treatment with this medication.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Arsenam 10 Injection 10 ml:
Co-administration of Arsenam 10 Injection 10 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Ziprasidone and Arsenam 10 Injection 10 ml but can be taken together if prescribed by a doctor. Contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Arsenam 10 Injection 10 ml:
Taking Trazodone with Arsenam 10 Injection 10 ml can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Arsenam 10 Injection 10 ml with Trazodone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. do not discontinue any medications without consulting a doctor.
How does the drug interact with Arsenam 10 Injection 10 ml:
Combining Amitriptyline and Arsenam 10 Injection 10 ml may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amitriptyline with Arsenam 10 Injection 10 ml may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Arsenam 10 Injection 10 ml:
Co-administration of Arsenam 10 Injection 10 ml with mifepristone can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Arsenam 10 Injection 10 ml with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, nausea, vomiting, constipation, abdominal cramping, chest pain, and/or swelling in the legs or feet, get medical attention. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Arsenam 10 Injection 10 ml:
Taking ceritinib with Arsenam 10 Injection 10 ml can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Although there is a interaction between Arsenam 10 Injection 10 ml with ceritinib, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Arsenam 10 Injection 10 ml:
Taking Arsenam 10 Injection 10 ml with risperidone can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Taking Risperidone with Arsenam 10 Injection 10 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
How does the drug interact with Arsenam 10 Injection 10 ml:
Co-administration of Indapamide with Arsenam 10 Injection 10 ml can increase the risk of abnormal heart rhythms.

How to manage the interaction:
Taking Indapamide and Arsenam 10 Injection 10 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, rapid heartbeat, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Arsenam 10 Injection 10 ml:
Using Arsenam 10 Injection 10 ml together with chloroquine can increase the risk of an irregular heart rhythm

How to manage the interaction:
There may be a possibility of interaction between Arsenam 10 Injection 10 ml and Chloroquine, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Arsenam 10 Injection 10 ml:
Taking Arsenam 10 Injection 10 ml with Mirtazapine can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Co-administration of Arsenam 10 Injection 10 ml with Mirtazapine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Arsenam 10 Injection 10 ml:
Taking Chlorpromazine with Arsenam 10 Injection 10 ml can increase the risk of irregular heart rhythm

How to manage the interaction:
Co-administration of Chlorpromazine with Arsenam 10 Injection 10 ml can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

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Alcohol

Safe if prescribed

It is not known if alcohol affects Arsenam 10 Injection 10 ml. Please consult your doctor.

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Pregnancy

Consult your doctor

Arsenic trioxide belongs to pregnancy category D. Arsenam 10 Injection 10 ml may cause harm to the unborn baby when used by pregnant women. If you are pregnant, planning for pregnancy or think you may be pregnant, talk to the doctor for advice.

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Breast Feeding

Consult your doctor

Arsenic trioxide passes into breast milk and may harm the baby. Therefore, avoid breastfeeding during treatment with Arsenam 10 Injection 10 ml.

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Driving

Safe if prescribed

Arsenam 10 Injection 10 ml has no or very little effect on your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Arsenam 10 Injection 10 ml.

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Kidney

Consult your doctor

If you have a history of kidney disease, inform your doctor before receiving Arsenam 10 Injection 10 ml. Caution is advised for patients with kidney failure.

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Children

Safe if prescribed

Arsenam 10 Injection 10 ml may not be recommended for children below 18 years. Please consult the doctor if you have any concerns.

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Heart

Arsenam 10 Injection 10 ml may increase the risk of heart problems. Therefore, please consult your doctor if you have any heart-related problems before using Arsenam 10 Injection 10 ml.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Arsenam 10 Injection 10 ml to geriatric patients. Your doctor will prescribe Arsenam 10 Injection 10 ml if the benefits outweigh the risks.

FAQs

Arsenam 10 Injection 10 ml is used to treat Acute promyelocytic leukaemia.

Arsenam 10 Injection 10 ml works by interfering with the growth of cancer cells and slowing their growth and spread in the body.

Arsenam 10 Injection 10 ml may reduce fertility in men. Discuss with the doctor about the risks of receiving Arsenam 10 Injection 10 ml if you are planning to father a child.

Arsenam 10 Injection 10 ml may cause increased blood sugar levels. Therefore, if you are diabetic or if you notice changes in blood sugar levels, consult the doctor.

In rare cases, Arsenam 10 Injection 10 ml may cause serious side effects in some individuals such as severe fever, breathing problems, heart issues, confusion, severe allergic reactions, vomit that is bloody, and decreased urination. It's important to watch for these symptoms and seek medical help right away if they happen.

Before taking Arsenam 10 Injection 10 ml, inform your doctor if you have any allergies, especially to any of Arsenam 10 Injection 10 ml ingredients. Inform if you are having any medical issues, as well as any medications you're taking. Also, inform your doctor if you're pregnant or planning to become pregnant or breastfeeding.

Generally, doctors may advise blood tests and ECGs to monitor blood counts, heart function, and other potential side effects. In necessary cases, your doctor may also include any other test based on individual health status.

Arsenam 10 Injection 10 ml may cause harm to the foetus. Discuss with your doctor if you're pregnant or planning to become pregnant before prescribing Arsenam 10 Injection 10 ml.

Arsenam 10 Injection 10 ml can pass into breast milk and may harm the baby. Discuss with your doctor if you're breastfeeding. In necessary or possible conditions, the doctor may probably tell you not to breastfeed during your treatment.

Arsenam 10 Injection 10 ml can be used to treat certain leukemia in pediatric patients under controlled doses and careful monitoring.

It may be due to Arsenam 10 Injection 10 ml. Because nausea and extreme tiredness are the reported side effects of the Arsenam 10 Injection 10 ml. In most cases, they usually vanish over time. If these effects worsen and are persistent please contact your doctor to find the actual reason and relief.

The use of Arsenam 10 Injection 10 ml can cause hyperglycemia. If you're diabetic, inform your doctor. Additionally, if you notice symptoms like extreme thirst, frequent urination, or blurred vision, contact your doctor immediately.

To relieve diarrhea while on Arsenam 10 Injection 10 ml, stay hydrated with water or electrolyte-rich drinks. Natural remedies like bananas, ginger, and probiotic-rich yogurt may help. If symptoms worsen, inform your doctor for prescribed medication or anti-diarrheal measures. Don’t take any medication without a prescription by your doctor.

Inform your doctor about the skin changes. They will assess and provide guidance on managing any skin reactions or recommend further treatment.

The common side effects of the Arsenam 10 Injection 10 ml are fatigue, pain, fever, headache, nausea, vomiting, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. If any of the side effects become persistent or worsen, inform your doctor for relief.

Country of origin

India

Manufacturer/Marketer address

F-30, Phase-1, Okhla Industrial Estate, New Delhi - 110020, India Manufacturing Unit: Plot No-10, Ida, Phase-I Jeedimetla, Hyderabad, 500055, (India)
Other Info - ARS0089

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