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Artin 150mg Capsule is used to treat rheumatoid arthritis, Wilson's disease, cystinuria, and lead poisoning. It helps remove excess copper from the body and prevent organ damage.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PENICILLAMINE-150MG

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Artin 150mg Capsule

Artin 150mg Capsule is used to treat severe rheumatoid arthritis (a joint disorder in which our immune system attacks our body cells), Wilson's disease (a genetic problem characterised by excess copper deposited in body parts like the eye, brain, and liver), and cystinuria (excess build-up of cystine in the urinary bladder and kidney).

Artin 150mg Capsule contains Penicillamine, which works by blocking the action of certain chemical messengers. For Wilson's disease, it binds to the extra copper in the body and causes it to leave the body through the urine.

Artin 150mg Capsule may cause common side effects such as protein in the urine, low platelet counts, stomach upset, diarrhoea, changes in taste, loss of appetite, mouth irritation, and mouth sores. Most of these side effects do not require medical attention. However, talk to your doctor if these side effects persist.

Do not take Artin 150mg Capsule if you are pregnant or planning a pregnancy, as Artin 150mg Capsule causes serious congenital disabilities. Artin 150mg Capsule should not be taken by breastfeeding mothers, as it passes into breast milk. Inform your doctor about your health condition and any medicines you are taking to rule out any unpleasant side effects.

Uses of Artin 150mg Capsule

Artin 150mg Capsule used in the treatment of rheumatoid arthritis, Wilson's disease, and cystinuria. The detailed uses of Artin 150mg Capsule are as follows:

  • Treats Wilson’s Disease: Artin 150mg Capsule helps to remove excess copper from the body by binding to it and promoting its excretion, preventing damage to the liver, brain, and other organs.
  • Manages Rheumatoid Arthritis: Artin 150mg Capsule is used to reduce joint inflammation, pain, stiffness, and slow joint damage, and disease progression over time.
  • Prevents Kidney Stone Formation in Cystinuria: Artin 150mg Capsule reduces urinary cystine levels, helping prevent cystine stone formation in patients with cystinuria.

Key Benefits

For Rheumatoid Arthritis:

  • Aids in reducing afflicted joints' stiffness, discomfort, and oedema.
  • Reduces joint degeneration and deformity by acting as a disease-modifying agent.
  • Improves everyday activities and mobility by managing symptoms.
  • Beneficial for those who don't react well to other arthritis medications.

For Wilson’s Disease:

  • Binds to excess copper in the body and aids in its excretion through the urine.
  • Prevents major problems by lowering copper accumulation in the liver, brain, and other organs.
  • Helps heal liver-related illnesses and reduces liver inflammation.
  • May help with speech, mobility, and tremors caused by copper buildup.

For Cystinuria:

  • Makes it easier to pass in urine by binding to cystine to form a more soluble molecule.
  • Reduces the risk of recurrent cystine-induced kidney stones.
  • Lessens discomfort and obstruction brought on by stone development.
  • Beneficial for patients who don't react well to dietary modifications and other therapies.

Directions for Use

  • Artin 150mg Capsule should be taken 1 hour before or 2 hours after a meal. Avoid drinking milk while taking Artin 150mg Capsule.
  • Your doctor will determine the dosage and timing of this medication based on your medical condition. Typically, it is taken 3-4 times daily.
  • Swallow Artin 150mg Capsule as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Artin 150mg Capsule Works

Artin 150mg Capsule contains penicillamine as a active ingredient. For rheumatoid arthritis, it blocks the action of certain chemical messengers responsible for inflammation and slowing the progress of the condition with certain joint diseases. It works in Wilson's disease by binding to the extra copper in the body and causing it to leave the body through the urine. Decreasing copper levels improves liver function and mental, mood, and nerve problems (like confusion and difficulty speaking or walking) caused by Wilson's disease.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Artin 150mg Capsule. It could lead to increased dizziness and drowsiness.

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Pregnancy

Unsafe

Artin 150mg Capsule is a pregnancy category D drug. It is not recommended to take Artin 150mg Capsule while you are pregnant. Artin 150mg Capsule may cause serious birth defects.

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Breast Feeding

Unsafe

Artin 150mg Capsule should not be used in breastfeeding mothers as Artin 150mg Capsule passes into breast milk.

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Driving

Caution

Artin 150mg Capsule may cause dizziness, drowsiness and tiredness; do not drive or operate heavy machinery if you feel dizzy.

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Liver

Unsafe

Artin 150mg Capsule is not recommended for the liver patients.

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Kidney

Caution

Artin 150mg Capsule should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.

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Children

Consult your doctor

Artin 150mg Capsule should be used in children under the care of the doctor. The dose may depend on the weight and age of the child.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Artin 150mg Capsule. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Caution

Artin 150mg Capsule should be used with extreme caution in elderly patients due to an increased risk of adverse effects.

What if I have taken an overdose of Artin 150mg Capsule

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Diet & Lifestyle Advise

Diet:

  • Limit consumption of spinach, wheat bran, nuts, beets and dairy products.
  • Avoid high salt intake and foods containing baking soda.
  • Drink plenty of fluids.
  • For Wilson’s disease: Try to avoid high-copper foods like shellfish, liver, nuts, chocolate, and mushrooms.

Lifestyle changes:

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Avoid smoking and alcohol consumption.
  • Try to strengthen muscles and relieve joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.

Physical activity:

  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.

Safety tips:

  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Follow work safety regulations if you are at risk of occupational exposure.
  • Wear necessary protective gear while working and do not take any contaminated material such as clothing or work gear to home. 

Have a query?

How Soon It Starts Working

  • The time required for Artin 150mg Capsule to start to work: Artin 150mg Capsule ideally shows its action within 30 to 90 minutes after administration
  • The time for which the effects of Artin 150mg Capsule last: The duration of action for Artin 150mg Capsule is clinically unknown.

What if you forget to take Artin 150mg Capsule

If you miss a dose of Artin 150mg Capsule, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Artin 150mg Capsule out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Artin 150mg Capsule if you are allergic (hypersensitive) to penicillamine or any of the other ingredients in it.
  • Inform your doctor if you have severe kidney problems, lupus erythematosus, agranulocytosis (a low white cell blood count), aplastic anaemia or thrombocytopenia (a blood disorder which causes bleeding into your skin, bruising and bleeding more than normal).
  • Do not take Artin 150mg Capsule if you are pregnant or planning to get pregnant and breastfeeding. This medicine may cause harm to the unborn baby if you take it while you are pregnant.
  • Caution should be required while taking Artin 150mg Capsule by elderly patients as they may be at greater risk of suffering side effects if you are taking Artin 150mg Capsule over a long time, especially if you are on a restricted diet, as this medicine increases the requirement for pyridoxine (Vitamin B6) so your doctor may also prescribe this vitamin for you.
  • If you are taking iron tablets, antacids, or digoxin (used to treat heart failure), please maintain two hours gap between these tablets and Artin 150mg Capsule.
  • Low blood cell counts have happened while taking Artin 150mg Capsule.
  • If blood cell counts get very low, this can lead to bleeding problems, infections, or anaemia, and sometimes, these have been deadly. 

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Drug-Drug Interactions:  Inform your doctor if you are taking any of these medicines, as there may be an interaction.

  • Iron supplements (carbonyl iron, ferrous sulfate)
    • Potential effect: May reduce the effectiveness of Artin 150mg Capsule.
  • Antacids (aluminium hydroxide, aluminium carbonate)
    Potential effect: May reduce the absorption of Artin 150mg Capsule.
  • Medicines to treat cancers (azathioprine, cyclophosphamide)
    Potential effect: May increase the risk of bone marrow suppression.

Drug-Food Interactions: Do not take copper-containing foods like shellfish, chocolate, nuts, mushrooms, and organ meats (liver pate, sweetbreads, etc.)

Drug-Disease Interactions: Inform your doctor if you have a history of the following conditions before taking Artin 150mg Capsule, as it may worsen your condition or cause complications.

  • Bone marrow suppression
  • Kidney dysfunction
  • Liver disease
  • Anaemia
  • Asthma
  • Allergies.

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Habit Forming

No

Therapeutic Class

[CHELATING AGENTS]

FAQs

Artin 150mg Capsule is used to treat‚ severe rheumatoid arthritis, Wilsons disease, and cystinuria. Rheumatoid arthritis is a joint disorder in which our immune system attacks our body cells. Wilson disease is a genetic problem characterized by excess copper deposited in body parts like the eye, brain, and liver, leading to metal toxicity. Cystinuria is the excess build-up of an amino acid called cystine in the urinary bladder and kidney, leading to harmful effects.

Artin 150mg Capsule works by blocking the actions of certain chemical messengers responsible for inflammation and preventing joint stiffness, thereby providing relief from rheumatoid arthritis.

Wilson's disease is a condition where the body cannot get rid of copper properly, causing damage to the liver, brain, and other organs. Artin 150mg Capsule contains penicillamine, which helps the body remove excess copper.

Avoid taking other medicines at the same time while taking Artin 150mg Capsule. If you take an iron supplement, take it at least 2 hours before or after you take Artin 150mg Capsule. Iron can make it harder for your body to absorb Artin 150mg Capsule. Avoid taking mineral supplements unless your doctor advises you to. Do not drink milk within 1 hour before or after you take Artin 150mg Capsule. Do not take copper-containing foods like shellfish, chocolate, nuts, mushrooms, and organ meats (liver pate, sweetbreads, etc.)

Artin 150mg Capsule may cause side effects such as protein in urine, low platelet counts, stomach upset or vomiting, diarrhoea, changes in taste, loss of appetite, mouth irritation, and mouth sores. These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.

Artin 150mg Capsule should not be taken during pregnancy or if you are trying to become pregnant, as Artin 150mg Capsule can cause birth defects, miscarriages or harm to unborn babies. Avoid becoming pregnant for at least 6 months after stopping the treatment with Artin 150mg Capsule.

Artin 150mg Capsule belongs to the class of medications called disease-modifying antirheumatic drugs (DMARDs). It is used to treat various conditions, including Wilson's disease, rheumatoid arthritis, and cystinuria.

No, Artin 150mg Capsule is not an antibiotic. It is actually a disease-modifying antirheumatic drug (DMARD) used to treat conditions like Wilson's disease, rheumatoid arthritis, and cystinuria.

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Country of origin

India
Other Info - AR34463
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