apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Azaplast 100 mg Injection 1's

Prescription drug
Trailing icon
Azaplast 100 mg Injection 1's, Pack of 1 INJECTION
Offers on medicine orders
All offers
axis icici
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Azaplast 100 mg Injection is used to treat Myelodysplastic syndrome, chronic myelomonocytic leukaemia, and acute myeloid leukaemia. It contains Azacitidine, a nucleoside metabolic inhibitor which works by preventing cancer cells from growing. It incorporates into the genetic material of the cells and interferes with the production of new DNA and RNA. This helps correct problems with the maturation and growth of young blood cells in the bone marrow, which causes myelodysplastic disorders.

Read more

Composition :

AZACITIDINE-100MG

Manufacturer/Marketer :

RPG Life Sciences Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Azaplast 100 mg Injection

Azaplast 100 mg Injection belongs to the group of medicines called anti-metabolites used in adults with higher-risk myelodysplastic syndromes, chronic myelomonocytic leukaemia, and acute myeloid leukaemia. These conditions affect the bone marrow and could cause problems with normal blood cell production.

Azaplast 100 mg Injection contains Azacitidine, which works by preventing cancer cells from growing. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.

In some cases, Azaplast 100 mg Injection may cause side effects such as nausea, vomiting, diarrhoea, constipation, weakness, headache, and injection site reactions. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Do not use Azaplast 100 mg Injection if you are pregnant or breastfeeding. Consult a doctor immediately if you become pregnant during treatment with Azaplast 100 mg Injection. This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Azaplast 100 mg Injection

Azaplast 100 mg Injection is used in the treatment of Myelodysplastic syndrome, chronic myelomonocytic leukaemia, and acute myeloid leukaemia. The detailed uses of Azaplast 100 mg Injection are as follows:<br/>• Myelodysplastic Syndromes (MDS): Azaplast 100 mg Injection helps improve blood counts and reduce the need for transfusions.<br/>• Acute Myeloid Leukemia (AML): Azaplast 100 mg Injection is used especially in patients who are in remission but cannot undergo intensive chemotherapy.<br/>• Chronic Myelomonocytic Leukemia (CMML): Azaplast 100 mg Injection is used to treat MDS and myeloproliferative disorders.<br/>

Have a query?

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Azaplast 100 mg Injection will be administered by a nurse or doctor.• Do not self-administer.

Medicinal Benefits

Azaplast 100 mg Injection belongs to the group of medicines called anti-metabolites used to treat myelodysplastic syndromes, chronic myelomonocytic leukaemia, and acute myeloid leukaemia. Azaplast 100 mg Injection contains Azacitidine, a nucleoside metabolic inhibitor which works by preventing cancer cells from growing. It incorporates into the genetic material of the cells and interferes with the production of new DNA and RNA. This helps correct problems with the maturation and growth of young blood cells in the bone marrow, which causes myelodysplastic disorders.

How Azaplast 100 mg Injection Works

Azaplast 100 mg Injection contains Azacitidine, which works by preventing cancer cells from growing. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.

Storage

• Store in a cool and dry place away from sunlight.• Keep Azaplast 100 mg Injection out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Azaplast 100 mg Injection
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.

What if I have taken an overdose of Azaplast 100 mg Injection

As Azaplast 100 mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Azaplast 100 mg Injection may cause diarrhoea, nausea and vomiting.

Drug Warnings

Do not use Azaplast 100 mg Injection if you are allergic to any of its components, have advanced liver cancer, or are breastfeeding. Inform the doctor if you have a low number of platelets, red or white blood cells, heart condition or heart attack, lung, kidney or liver diseases. Seek immediate medical attention if you experience symptoms of liver failure (jaundice, abdominal bloating, shaking, drowsiness, and easy bruising), kidney failure (back pain, increased thirst, swelling of legs and feet, reduced passing of water, dizziness, rapid pulse, nausea, vomiting, reduced appetite, confusion, fatigue or restlessness), fever, pneumonia (shortness of breath or chest pain accompanied with fever), low levels of platelets (bleeding such as blood in stools due to bleeding in the stomach), or allergic reaction (rash, difficulty breathing, itching, or swelling of lips).

Drug-Drug Interactions

verifiedApollotooltip
AzacitidineYellow fever vaccine
Critical
AzacitidineClozapine
Severe

Drug-Drug Interactions

Login/Sign Up

AzacitidineYellow fever vaccine
Critical
How does the drug interact with Azaplast 100 mg Injection:
Taking Yellow fever vaccine with Azaplast 100 mg Injection can increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Azaplast 100 mg Injection and the Yellow fever vaccine, you can take these medicines together if prescribed by a doctor. If you notice any signs of infection, it's important to contact a doctor right away. Do not stop using any medications without consulting a doctor.
AzacitidineClozapine
Severe
How does the drug interact with Azaplast 100 mg Injection:
Using clozapine together with Azaplast 100 mg Injection can lower white blood cell count and may affect the bone marrow function, that may develop serious infections as a result.

How to manage the interaction:
There may be a possibility of interaction between Azaplast 100 mg Injection and Clozapine, but it can be taken if prescribed by a doctor. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not stop using any medications without a doctor's advice.
AzacitidineAdalimumab
Severe
How does the drug interact with Azaplast 100 mg Injection:
Taking Adalimumab with Azaplast 100 mg Injection may raise the risk of severe infections.

How to manage the interaction:
Taking Azaplast 100 mg Injection with Adalimumab together can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AzacitidineGolimumab
Severe
How does the drug interact with Azaplast 100 mg Injection:
Taking Azaplast 100 mg Injection with Golimumab can raise the risk of severe infections.

How to manage the interaction:
Co-administration of Azaplast 100 mg Injection with Golimumab can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AzacitidineEfalizumab
Severe
How does the drug interact with Azaplast 100 mg Injection:
Using efalizumab together with Azaplast 100 mg Injection may increase the risk of serious infections.

How to manage the interaction:
Taking Azaplast 100 mg Injection with Efalizumab together can result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms - complications, infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, pain or burning during urination - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AzacitidineFilgrastim
Severe
How does the drug interact with Azaplast 100 mg Injection:
Coadministration of Filgrastim with Azaplast 100 mg Injection can reduce the effects of Filgrastim.

How to manage the interaction:
Although there is an interaction between filgrastim and Azaplast 100 mg Injection, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AzacitidineFingolimod
Severe
How does the drug interact with Azaplast 100 mg Injection:
The use of fingolimod in conjunction with Azaplast 100 mg Injection may raise the risk of severe infections.

How to manage the interaction:
Co-administration of Azaplast 100 mg Injection with Fingolimod can possibly result in an interaction, but it can be taken if your doctor has advised it. However, Consult a doctor immediately if you have a fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.
AzacitidineBaricitinib
Severe
How does the drug interact with Azaplast 100 mg Injection:
Taking baricitinib and Azaplast 100 mg Injection can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Azaplast 100 mg Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
AzacitidineCladribine
Severe
How does the drug interact with Azaplast 100 mg Injection:
The use of cladribine with Azaplast 100 mg Injection can increase the risk of infections.

How to manage the interaction:
Taking Azaplast 100 mg Injection with Cladribine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience a fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
AzacitidineTofacitinib
Severe
How does the drug interact with Azaplast 100 mg Injection:
Taking Azaplast 100 mg Injection with tofacitinib can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Azaplast 100 mg Injection and Tofacitinib, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat a balanced diet.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Azaplast 100 mg Injection Substitute

Substitutes safety advice
bannner image

Alcohol

Consult your doctor

It is not known if alcohol affects Azaplast 100 mg Injection. Please consult your doctor.

bannner image

Pregnancy

Unsafe

Azacitidine belongs to pregnancy category D. Azaplast 100 mg Injection should not be used during pregnancy as it may harm the baby. Consult the doctor immediately if you become pregnant during treatment with Azaplast 100 mg Injection.

bannner image

Breast Feeding

Unsafe

It is unknown if Azacitidine passes into breast milk. Breastfeeding is not recommended during treatment with Azaplast 100 mg Injection.

bannner image

Driving

Caution

Azaplast 100 mg Injection may cause dizziness and tiredness. Avoid driving or operating machinery if you experience any side effects that might lessen your ability to do so.

bannner image

Liver

Caution

If you have a history of liver disease, inform your doctor before receiving Azaplast 100 mg Injection. This medicine should be used with caution in patients with severe pre-existing liver impairment.

bannner image

Kidney

Caution

If you have a history of kidney disease, inform your doctor before receiving Azaplast 100 mg Injection. Monitoring patients with kidney impairment is advised.

bannner image

Children

Unsafe

Azaplast 100 mg Injection is not recommended for children below 18 years as safety and effectiveness have not been established.

FAQs

Azaplast 100 mg Injection is used to treat Myelodysplastic syndrome, chronic myelomonocytic leukaemia, and acute myeloid leukaemia.

Azaplast 100 mg Injection works by preventing cancer cells from growing. Thereby, it helps treat cancer.

Men should avoid fathering a child whilst on treatment with Azaplast 100 mg Injection. Consult the doctor if you wish to conserve your sperm before starting the treatment. Use effective contraception during the treatment with Azaplast 100 mg Injection and for three months after stopping the treatment.

Azaplast 100 mg Injection may cause a serious immune reaction known as differentiation syndrome. Consult the doctor immediately if you experience fever, rash, difficulty breathing, cough, decreased urine, rapid weight gain, low blood pressure, or swelling of the legs or arms.

No, Azaplast 100 mg Injection is not a vesicant. It is a cytotoxic chemotherapy drug used to treat certain types of blood cancer, such as myelodysplastic syndrome (MDS). It is not known to cause severe tissue damage if it leaks from the injection site.

No, Azaplast 100 mg Injection does not cause hair loss.

Yes, Azaplast 100 mg Injection is a type of chemotherapy. It is used to treat certain types of blood cancers, such as myelodysplastic syndrome (MDS) and some forms of leukaemia.

Yes, Azaplast 100 mg Injection is a cytotoxic drug. It works by interfering with the growth of cancer cells, which helps to slow down or stop their multiplication.

The common side effects of Azaplast 100 mg Injection are nausea, vomiting, diarrhoea, constipation, weakness, headache, and injection site reactions. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

463, 4 Th Floor, Rpg House, Dr. Annie Besant Road, Worli, Mumbai €“ 400 030. Maharashtra, India
Other Info - AZA0114

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:05 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.6468.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050794s011lbl.pdf
  3. https://medlineplus.gov/druginfo/meds/a607068.html

Buy best Neoplastic Disorders products by

whatsapp Floating Button