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  3. Azel 40 mg Capsule 28's

Azel 40 mg Capsule 28's, Pack of 28 CapsuleS
Azel 40 mg Capsule 28's, Pack of 28 CapsuleS
Azel 40 mg Capsule 28's, Pack of 28 CapsuleS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Azel 40 mg Capsule is used to treat prostate cancer. It contains Enzalutamide, an androgen receptor blocker (inhibitor) that blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow; this can slow the growth of the cancer and may shrink it. Enzalutamide is only for use in men. Men using this medication must use effective birth control whenever they have sex during their treatment and for three months after their final dose.

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Composition :

ENZALUTAMIDE-40MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Azel 40 mg Capsule

Azel 40 mg Capsule belongs to a group of medicines known as androgen receptor inhibitors. It is used to treat prostate cancer. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs. Prostate cancer is a type of cancer that only occurs in men and affects the prostate gland, a tiny gland under the bladder that produces semen.

Azel 40 mg Capsule contains Enzalutamide, an androgen receptor blocker (inhibitor). Enzalutamide blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow. This can slow the growth of the cancer and may shrink it.

Use this medicine as directed by your doctor. You may sometimes experience trouble breathing (pneumonia), weakness or feeling more tired than usual, back pain, diarrhoea, pain in your joints, swelling (in your hands, arms, legs or feet), muscle or bone pain, muscle weakness, headache, cold-like symptoms, dizziness, high blood pressure and trouble falling or staying asleep (insomnia). Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

Enzalutamide is only for use in men. Men using this Azel 40 mg Capsule must use effective birth control whenever they have sex during your treatment and for three months after their final dose. In rare cases, Azel 40 mg Capsule may cause seizures, so tell your doctor if you have or have ever had seizures. Because of the risk of seizure associated with Azel 40 mg Capsule use, patients should be advised of the risk of engaging in any activity where sudden loss of consciousness could cause serious harm to themselves or others. Consumption of alcohol is strictly avoided.

Uses of Azel 40 mg Capsule

Azel 40 mg Capsule is used in the treatment of Prostate Cancer. The detailed uses of Azel 40 mg Capsule are as follows:<br/> • Metastatic castration-resistant prostate cancer (mCRPC): Azel 40 mg Capsule is used to treat prostate cancer that continues to progress despite low testosterone levels. It is typically prescribed when the cancer has spread to other parts of the body and no longer responds to hormone therapy.<br/> • Non-metastatic castration-resistant prostate cancer (nmCRPC): Azel 40 mg Capsule is used in patients whose prostate cancer has not yet spread but is no longer responding to medical or surgical treatments that lower testosterone.<br/> • Hormone-sensitive metastatic prostate cancer: Azel 40 mg Capsule is used in combination with androgen deprivation therapy (ADT) to treat prostate cancer that has spread but still responds to hormone-lowering treatments.<br/>

Directions for Use

  • Azel 40 mg Capsule can be taken with or without food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Azel 40 mg Capsule as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Azel 40 mg Capsule contains Enzalutamide, which belongs to a group of medicines known as androgen receptor inhibitors. Most prostate cancers require testosterone to grow. In men, the testicles produce the majority of testosterone. Adrenal glands (Just above each kidney) produce a small quantity of testosterone. Enzalutamide is preventing testosterone from reaching cancer cells in the prostate. This can inhibit the growth of the cancer and even cause it to shrink.

How Azel 40 mg Capsule Works

Azel 40 mg Capsule contains Enzalutamide, an androgen receptor blocker (inhibitor). Enzalutamide blocks testosterone from reaching prostate cancer cells. Most prostate cancers require testosterone to grow. This can slow the growth of the cancer and may shrink it.

Storage

• Store in a cool and dry place away from sunlight.• Keep Azel 40 mg Capsule out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Azel 40 mg Capsule
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Include omega-3 rich foods like fatty fish, ground flax, flaxseed oil, and walnuts.
  • Consume calcium-rich dairy products for bone health.
  • Eat green and leafy vegetables for essential nutrients.
  • Include lean protein sources like eggs and whole grains.
  • Use herbs and spices for added flavor and nutrition.
  • Choose fortified foods for extra nutritional benefits.
  • Get plenty of sleep for overall health and well-being.

What if I have taken an overdose of Azel 40 mg Capsule

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Azel 40 mg Capsule may include seizures. Seek immediate medical attention if you observe any symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Do not take Azel 40 mg Capsule if you are allergic or hypersensitive to any component present in it. You must take Enzalutamide according to the instructions your doctor or pharmacist gives you. You must take Enzalutamide exactly as prescribed by your doctor or pharmacist. You must take the correct dose, not more or less. Consult your healthcare team before discontinuing Azel 40 mg Capsule or missing a dose. Talk to your doctor before taking Azel 40 mg Capsule if you have severe allergic reactions to medicines or foods or suffer from any medical illness. Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant.

Drug-Drug Interactions

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EnzalutamideRegorafenib
Critical
EnzalutamideZiprasidone
Critical

Drug-Drug Interactions

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EnzalutamideRegorafenib
Critical
How does the drug interact with Azel 40 mg Capsule:
Taking Azel 40 mg Capsule with Regorafenib may decrease the blood levels of Regorafenib, which may make Regorafenib less effective in treating your condition.

How to manage the interaction:
Taking Azel 40 mg Capsule with Regorafenib is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideZiprasidone
Critical
How does the drug interact with Azel 40 mg Capsule:
Taking Azel 40 mg Capsule with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Azel 40 mg Capsule with Ziprasidone is not recommended, as it may lead to an interaction it can be taken if prescribed by the doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
EnzalutamideDronedarone
Critical
How does the drug interact with Azel 40 mg Capsule:
Co-administration of Azel 40 mg Capsule and Dronedarone together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Azel 40 mg Capsule and Dronedarone together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EnzalutamideLurasidone
Critical
How does the drug interact with Azel 40 mg Capsule:
Co-administration of Lurasidone with Azel 40 mg Capsule may result in significantly lower blood levels of Lurasidone, making the medication less effective.

How to manage the interaction:
Taking Lurasidone with Azel 40 mg Capsule is not recommended as it may lead to interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
EnzalutamideRanolazine
Critical
How does the drug interact with Azel 40 mg Capsule:
Taking Azel 40 mg Capsule may decrease the blood levels of Ranolazine, which may make Ranolazine less effective.

How to manage the interaction:
Taking Azel 40 mg Capsule with Ranolazine is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideDelavirdine
Severe
How does the drug interact with Azel 40 mg Capsule:
Taking Azel 40 mg Capsule and Delavirdine together may decrease the blood levels of delavirdine, which may make delavirdine less effective in treating your HIV infection.

How to manage the interaction:
There may be a possibility of interaction between Azel 40 mg Capsule and Delavirdine, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
EnzalutamideMethadone
Severe
How does the drug interact with Azel 40 mg Capsule:
When Azel 40 mg Capsule is taken with Methadone, it may lower your blood levels of methadone, which might make the medicine less effective at treating your disease.

How to manage the interaction:
Although taking Azel 40 mg Capsule and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you're having any of these symptoms -watery eyes, runny nose, sneezing, yawning, excessive sweating, fever, chills, flushing, restlessness, anger, anxiety, eye problems, shaking, rapid heartbeat, body aches, involuntary kicking and twitching, abdominal cramping, decreased hunger, nausea, vomiting, diarrhea, and weight loss, consult the doctor. Do not discontinue any medications without a doctor's advice.
EnzalutamideBosutinib
Severe
How does the drug interact with Azel 40 mg Capsule:
Taking bosutinib with Azel 40 mg Capsule can decrease the blood levels of bosutinib, which decreases bosutinib's ability to treat your condition.

How to manage the interaction:
Although there is an interaction between Azel 40 mg Capsule and Bosutinib, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EnzalutamideCariprazine
Severe
How does the drug interact with Azel 40 mg Capsule:
When Cariprazine is taken with Azel 40 mg Capsule, it reduces the blood levels of cariprazine which may make the medication less effective.

How to manage the interaction:
Although taking Cariprazine and Azel 40 mg Capsule together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any unusual symptoms or if your condition worsens, make sure to contact a doctor. Do not stop using any medications without talking to a doctor.
EnzalutamideGatifloxacin
Severe
How does the drug interact with Azel 40 mg Capsule:
Taking Azel 40 mg Capsule and Gatifloxacin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Azel 40 mg Capsule and Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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ENZALUTAMIDE-40MGHerbal products/medicines
Moderate

Drug-Food Interactions

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ENZALUTAMIDE-40MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Taking St. John's Wort products during Azel 40 mg Capsule treatment may lead to decrease in the effectiveness of Azel 40 mg Capsule. Avoid St. John's Wort products during Azel 40 mg Capsule treatment

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Azel 40 mg Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Azel 40 mg Capsule .

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Pregnancy

Not applicable

Enzalutamide is only for use in men. Women should not take this medication.

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Breast Feeding

Not applicable

Enzalutamide is only for use in men. Women should not take this medication.

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Driving

Unsafe

Azel 40 mg Capsule may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

bannner image

Liver

Caution

In patients with mild or moderate liver impairment, there is no need to alter the initial dose. There is no information available on patients with severe liver impairment.

bannner image

Kidney

Caution

In patients with mild or moderate kidney impairment, there is no need to alter the initial dose. There is no information available on patients with severe kidney impairment.

bannner image

Children

Unsafe

The safety and effectiveness of Azel 40 mg Capsule in pediatric patients have not been established.

Have a query?

FAQs

Azel 40 mg Capsule is used to treat prostate cancer in men.

Most prostate cancers require testosterone to grow. Azel 40 mg Capsule contains Enzalutamide, which blocks testosterone, a hormone, from reaching prostate cancer cells. Thus, Azel 40 mg Capsule can slow the cancer&#039;s growth and cause it to shrink.

Azel 40 mg Capsule is only for use in men. Women should not take this medication, especially if they are or may become pregnant or are breast-feeding.

In some cases, Azel 40 mg Capsule may cause decreased fertility in men. However, you should not assume that your female partner cannot become pregnant. Please discuss with your doctor if you have any concerns.

Enzalutamide, a prostate cancer medication, is used to treat prostate cancer.

Seizures may occur in patients receiving Azel 40 mg Capsule . So, patients who have had a seizure, please inform your doctor about your condition. Your doctor may monitor your condition closely.

Yes, Enzalutamide was generally a well-tolerated medication. Take Azel 40 mg Capsule pills exactly as directed by your healthcare provider. Do not change your dose or stop taking Azel 40 mg Capsule unless your healthcare physician instructs you. If you encounter side symptoms, your healthcare provider may temporarily discontinue your Azel 40 mg Capsule therapy or adjust your Azel 40 mg Capsule dose.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - AZE0088

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 23, 2025 | 8:42 AM IST

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Reference

  1. https://medlineplus.gov/druginfo/meds/a612033.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/203415lbl.pdf
  3. https://aarkpharma.com/product/obnyx-enzalutamide-price-in-india/
  4. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/enzalutamide
  5. https://www.drugs.com/drug-interactions/enzalutamide-index.html

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