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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Azenate Nasal Spray is used to treat allergic rhinitis and related symptoms such as sneezing, runny or blocked nose, nasal congestion, sinus discomfort, and watery eyes. It helps reduce nasal inflammation and control allergic reactions, providing effective and long-lasting relief from both nasal blockage and allergy symptoms.

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Manufacturer/Marketer :

Entod Pharmaceuticals Ltd

Consume Type :

NASAL

Return Policy :

Not Returnable

Expires on or after :

About Azenate Nasal Spray

Azenate Nasal Spray is used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose or watery eyes. An allergy is a condition that occurs when the immune system reacts to a foreign substance.

Azenate Nasal Spray contains Fluticasone and Azelastine. Fluticasone works by stopping the release of certain chemicals in the body that cause inflammatory reactions. Azelastine works by blocking histamine, a substance responsible for causing allergic reactions.

Use Azenate Nasal Spray as advised by your doctor. Some people may experience headaches, taste changes or nose bleeds. Most of these side effects of Azenate Nasal Spray do not require medical attention and resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic to Azenate Nasal Spray or any other medicines. Consult your doctor if you are pregnant or breastfeeding before using Azenate Nasal Spray. Azenate Nasal Spray is not recommended for children below six years of age.

Uses of Azenate Nasal Spray

Azenate Nasal Spray is used to treat allergic symptoms. The detailed uses of Azenate Nasal Spray are as follows:

  • Allergic rhinitis: Azenate Nasal Spray reduces sneezing, nasal congestion, and a runny nose due to allergies.
  • Perennial allergies: Azenate Nasal Spray helps to control nasal symptoms triggered by allergens.

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Directions for Use

  • Azenate Nasal Spray is for nasal use only.
  • It is recommended to spray Azenate Nasal Spray twice daily into each nostril, or as prescribed by your doctor.
  • Check the label for directions before using Azenate Nasal Spray.
  • Shake the nasal spray bottle gently before each use.
  • Blow your nose and remove the protective cap. Before the first use, press the pump a few times until an even spray is released.
  • Insert the tip of the bottle into a nostril while closing the other nostril and spray the medicine into your nose. Keep your head straight and breathe gently. Repeat the same process for the other nostril.
  • If Azenate Nasal Spray accidentally gets sprayed into your mouth or eyes, rinse with water thoroughly.

Medicinal Benefits

  • Azenate Nasal Spray provides effective relief from allergic symptoms such as sneezing, runny or blocked nose, nasal congestion, and watery eyes.
  • It reduces nasal inflammation, itching, and irritation caused by allergic reactions.
  • It helps clear nasal passages, improving breathing comfort.
  • It minimizes postnasal drip by controlling excess mucus production associated with allergies.

How Azenate Nasal Spray Works

Azenate Nasal Spray is a combination of two drugs: Fluticasone (corticosteroid) and Azelastine (antihistamine/antiallergic).•Fluticasone belongs to the class of corticosteroids that work by acting inside the nasal lining cells and stopping the release of certain chemicals in the body that cause inflammatory reactions, thereby relieving sneezing, runny or blocked nose, and sinus discomfort.• Azelastine belongs to the class of antihistamines (antiallergic drugs) that work by blocking histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, a runny nose, watery eyes, itching, swelling, congestion, or stiffness.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Azenate Nasal Spray

An overdose of Azenate Nasal Spray may cause unpleasant effects. If you have any unusual signs or symptoms, please consult a doctor immediately.

Drug Warnings

  • Please inform your doctor if you are allergic to Azenate Nasal Spray or any other medicines.
  • Do not use the Azenate Nasal Spray if you are pregnant or breastfeeding without consulting a doctor.
  • Azenate Nasal Spray is not recommended for children below six years of age.
  • If you experience vision changes, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds, or increased drowsiness, stop taking Azenate Nasal Spray and consult a doctor immediately.
  • Avoid contact with people who have infections or are sick, as Azenate Nasal Spray may weaken the immune system, causing infections to be easily contracted.
  • If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of the eyes, ulcers, or sores inside the nose, inform your doctor before taking Azenate Nasal Spray.

Drug-Drug Interactions

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Fluticasone PropionateDesmopressin
Critical
Fluticasone PropionateMifepristone
Critical

Drug-Drug Interactions

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Fluticasone PropionateDesmopressin
Critical
How does the drug interact with Azenate Nasal Spray 10 ml:
Co-administration of desmopressin together with fluticasone may increase the risk of hyponatremia, a condition associated with low levels of salt in the blood.

How to manage the interaction:
Coadministration of desmopressin and Azenate Nasal Spray 10 ml is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, headache, lethargy, irritability, difficulty concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination and sudden weight gain contact doctor immediately. Do not discontinue any medications without consulting a doctor.
Fluticasone PropionateMifepristone
Critical
How does the drug interact with Azenate Nasal Spray 10 ml:
Co-administration of Azenate Nasal Spray 10 ml with Mifepristone can increase the risk of side effects.

How to manage the interaction:
Taking Mifepristone and Azenate Nasal Spray 10 ml is not recommended, but can be taken if prescribed by a doctor. Do no discontinue any medications without consulting a doctor.
Fluticasone PropionateVoriconazole
Severe
How does the drug interact with Azenate Nasal Spray 10 ml:
Taking Azenate Nasal Spray 10 ml with Voriconazole may significantly increase the absorption of fluticasone into the blood stream.

How to manage the interaction:
Although taking Voriconazole and Azenate Nasal Spray 10 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience muscle weakness, excessive growth of facial or body hair contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Fluticasone PropionateAtazanavir
Severe
How does the drug interact with Azenate Nasal Spray 10 ml:
When Azenate Nasal Spray 10 ml is taken with atazanavir , the amount of Azenate Nasal Spray 10 ml in the blood may increase.

How to manage the interaction:
Although there is a interaction, atazanavir can be taken with Azenate Nasal Spray 10 ml if prescribed by the doctor. Consult the doctor if you experience swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, menstrual irregularities, excessive growth of facial or body hair,. Do not discontinue medications until doctor recommends it.
Fluticasone PropionateConivaptan
Severe
How does the drug interact with Azenate Nasal Spray 10 ml:
When Azenate Nasal Spray 10 ml is taken with conivaptan, the amount of Azenate Nasal Spray 10 ml in the blood may increase.

How to manage the interaction:
Although there is a interaction, conivaptan can be taken with Azenate Nasal Spray 10 ml if prescribed by the doctor. Consult the doctor if you experience swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, menstrual irregularities, excessive growth of facial or body hair,. Do not discontinue medications until doctor recommends it.
Fluticasone PropionateKetoconazole
Severe
How does the drug interact with Azenate Nasal Spray 10 ml:
Using Azenate Nasal Spray 10 ml with ketoconazole may increase the blood levels and effects of Azenate Nasal Spray 10 ml.

How to manage the interaction:
Although taking Ketoconazole and Azenate Nasal Spray 10 ml together can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities and excessive growth of facial or body hair contact your doctor immediately. Do no discontinue any medications without consulting a doctor.
Fluticasone PropionateCladribine
Severe
How does the drug interact with Azenate Nasal Spray 10 ml:
Taking Cladribine with Azenate Nasal Spray 10 ml can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a interaction, cladribine can be taken with Azenate Nasal Spray 10 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Fluticasone PropionateMibefradil
Severe
How does the drug interact with Azenate Nasal Spray 10 ml:
When Azenate Nasal Spray 10 ml is taken with mibefradil, the amount of Azenate Nasal Spray 10 ml in the blood may increase.

How to manage the interaction:
Although there is a interaction, mibefradil can be taken with Azenate Nasal Spray 10 ml if prescribed by the doctor. Consult the doctor if you experience swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, menstrual irregularities, excessive growth of facial or body hair,. Do not discontinue medications until doctor recommends it.
Fluticasone PropionateClarithromycin
Severe
How does the drug interact with Azenate Nasal Spray 10 ml:
Clarithromycin may increase the absorption of Azenate Nasal Spray 10 ml into the blood stream.

How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Azenate Nasal Spray 10 ml if prescribed by the doctor. Consult the prescriber if you experience side effects such as swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not stop using any medications without a doctor's advice.
Fluticasone PropionatePosaconazole
Severe
How does the drug interact with Azenate Nasal Spray 10 ml:
Posaconazole can greatly enhance the absorption of fluticasone into the bloodstream. You may have a higher chance of experiencing side effects of Fluticasone.

How to manage the interaction:
Although using Posaconazole and Azenate Nasal Spray 10 ml together can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience any side effects of Fluticasone, such as Swelling, weight gain, high blood glucose, muscular weakness, depression, acne, thinning skin, easy bruising, menstruation abnormalities, excessive facial or body hair growth, abnormal body fat distribution, particularly in the face, neck, back, and waist, contact your doctor immediately. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Healthy Eating Habits:

  • Add ginger to foods or tea as it may help reduce cough, nasal irritation, and inflammation.
  • Stay well hydrated by drinking fluids at room temperature to ease sneezing, a runny nose, and a cough.
  • Avoid foods that you know can trigger allergic reactions.

Physical Activity:

  • Engage in regular, moderate exercise to support immunity and overall respiratory health.

Monitoring & Safety:

  • Avoid exposure to known allergens such as dust, pollen, or other triggers specific to you.
  • Maintain good personal hygiene and keep your surroundings clean to reduce infection risk.

Stress Management:

Practice stress-relieving techniques such as meditation, deep breathing, or progressive muscle relaxation to support immune function.

Habit Forming

No

Therapeutic Class

ANTIALLERGIC

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Alcohol

Caution

It is unknown whether it is safe to consume alcohol with Azenate Nasal Spray. However, as a precautionary measure, it is advisable not to take or limit alcohol.

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Pregnancy

Caution

The safety of Azenate Nasal Spray in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown whether Azenate Nasal Spray is excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Azenate Nasal Spray may cause drowsiness in some people. Therefore, drive only if you are alert after taking Azenate Nasal Spray.

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Liver

Consult your doctor

Inform your doctor before prescribing the Azenate Nasal Spray if you have a history of liver impairment/disorder. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Consult your doctor

Inform your doctor before receiving the Azenate Nasal Spray if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Azenate Nasal Spray is not recommended for children below six years as the safety and effectiveness were not established.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Azenate Nasal Spray. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Caution

Azenate Nasal Spray should be used with caution in elderly patients, starting at a lower dose because of potentially decreased organ function. Consult your doctor if you have any concerns.

FAQs

Azenate Nasal Spray is used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose‚ or watery eyes.

Azenate Nasal Spray is a combination of two drugs: Fluticasone (corticosteroid) and Azelastine (antihistamine/antiallergic). Fluticasone works by acting inside the nasal lining cells and stopping the release of certain chemicals in the body that cause inflammatory reactions, thereby relieving sneezing, runny or blocked nose and sinus discomfort. On the other hand, Azelastine belongs to the class of antihistamines (antiallergic drugs) that works by blocking histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, runny nose, watery eyes, itching, swelling, congestion, or stiffness. Together, both of them effectively treat allergic symptoms.

It is recommended that you avoid taking grapefruit juice with Azenate Nasal Spray as it may lead to adrenal insufficiency and Cushing’s syndrome (increased cortisol hormone in the body).

Your rhinitis symptoms may improve over several days of regular use. Call your healthcare provider if your symptoms do not improve or worsen.

You are not recommended to take more than the prescribed dose of Azenate Nasal Spray or for a prolonged time as it may cause adverse effects such as changes in body fat (especially in the back, waist, neck, and face), easy bruising, skin thinning, increased facial hair or acne, loss of interest in sex, impotence or menstrual problems. However, if you experience any of these symptoms while taking Azenate Nasal Spray, please consult a doctor immediately.

No, you are recommended not to use Azenate Nasal Spray if you have a recent nose operation or have any nose infections, as it may lead to nose bleeding and excessive pain in the nose, leading to further worsening of your condition. Consult your doctor and do as advised for the best results.

No, Azenate Nasal Spray is not used to treat asthma attacks. It is used to prevent allergic symptoms that can cause asthma. Therefore, it is recommended to always carry a rescue inhaler to treat asthma attacks.

Azenate Nasal Spray contains Fluticasone, which belongs to the class of corticosteroids, and it may result in the development of glaucoma and/or cataracts. Therefore, close monitoring is warranted in patients with a change in vision or a history of increased intraocular pressure, glaucoma, and/or cataracts.

Use Azenate Nasal Spray as advised by your doctor. Place the tip of the bottle into one nostril while closing the other nostril. Spray towards the side of your nostril, keeping your head upright and breathing in softly.

Store in a cool and dry place at room temperatures. Protect from light. Keep it out of reach of children. Do not refrigerate. Follow the local guidelines for disposal of Azenate Nasal Spray.

Azenate Nasal Spray causes side effects as headache, nose bleeds, and taste change. These side effects do not require any medical treatment. They will reduce by time.

Country of origin

INDIA

Manufacturer/Marketer address

Ashirwad building, S.V.Road, Opp. Badi Masjid, Bandra(W), Mumbai-400050, INDIA
Other Info - AZE0029

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