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compositionComposition:AZATHIOPRINE-75MG
prescriptionPrescription Medicine

Azotas-75 Tablet 10's is an immunosuppressant primarily used to prevent kidney transplant rejection and manage the symptoms of active rheumatoid arthritis (a condition in which the immune system attacks the joints). It suppresses the overactive immune system by inhibiting the proliferation of certain white blood cells, thereby helping to prevent the body from rejecting newly transplanted organs. It also helps relieve joint pain and inflammation and slows disease progression in patients with rheumatoid arthritis.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AZATHIOPRINE-75MG

Manufacturer/Marketer :

Tas Med India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Azotas-75 Tablet 10's

Azotas-75 Tablet 10's is used to prevent rejection of kidney transplants. It is also used to treat symptoms of active rheumatoid arthritis (a condition in which the immune system attacks the joints, causing pain and inflammation).

Azotas-75 Tablet 10's contains Azathioprine (an immunosuppressant), which works by calming the immune system. It prevents certain white blood cells (especially T and B cells that attack foreign invaders and defend the body against harmful cells) from proliferating excessively. As a result, Azotas-75 Tablet 10's helps prevent the body from attacking a transplanted organ and reduces inflammation in joint tissues.

Take Azotas-75 Tablet 10's exactly as prescribed by your doctor. Swallow it whole with a glass of water, and do not crush or chew it. Azotas-75 Tablet 10's may cause common side effects, including nausea, headache, vomiting, diarrhoea, dizziness, loss of appetite, increased liver enzymes, reduced resistance to infections, and leukopenia (decreased white blood cell count). Please consult your doctor if these side effects persist or worsen.

Do not take Azotas-75 Tablet 10's if you are allergic to any of its ingredients or if you are pregnant, planning to become pregnant, or breastfeeding. Azotas-75 Tablet 10's should not be given to children, as its safety and efficacy have not been established. Inform your doctor before taking Azotas-75 Tablet 10's if you have any bacterial, fungal, or viral infections, liver or kidney problems, or are taking other immunosuppressant or chemotherapy medications.

Uses of Azotas-75 Tablet 10's

Azotas-75 Tablet 10's is used to prevent kidney transplant rejection and manage rheumatoid arthritis. The detailed uses of Azotas-75 Tablet 10's are as follows:

  • Prevention of organ rejection in kidney transplantation: Azotas-75 Tablet 10's is used along with other medications to help prevent the body from rejecting a transplanted kidney.
  • Treatment of severe active rheumatoid arthritis: Azotas-75 Tablet 10's is also prescribed to reduce signs and symptoms in patients with rheumatoid arthritis that have not improved with standard treatments, such as disease-modifying antirheumatic drugs (DMARDs) or nonsteroidal anti-inflammatory drugs (NSAIDs).

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Directions for Use

  • Azotas-75 Tablet 10's can be taken with or without food. However, if you experience stomach upset, take it with food. Avoid taking it with milk or dairy products, as they may reduce its effectiveness.
  • Your doctor will determine the dosage and timing of this medication based on your medical condition. If taken regularly, it is typically recommended 1-2 times daily.
  • Swallow Azotas-75 Tablet 10's as a whole with a glass of water.
  • Do not crush, chew, or break it.

Key Benefits

Azotas-75 Tablet 10's offers the following medicinal benefits:

  • Suppresses the immune system to help prevent rejection of newly transplanted organs, such as kidneys.
  • Relieves joint pain and inflammation while slowing joint damage and disease progression in patients with rheumatoid arthritis.
  • May help control an overactive immune system in various autoimmune conditions (such as ulcerative colitis, lupus, and autoimmune hepatitis)
  • May decrease the need for long-term steroid use in patients with severe inflammatory skin disorders.

How Azotas-75 Tablet 10's Works

Azotas-75 Tablet 10's contains Azathioprine (an immunosuppressant) that works by modulating the immune system. It prevents certain white blood cells (especially T and B cells that attack foreign invaders and defend the body against harmful cells) from proliferating excessively. As a result, Azotas-75 Tablet 10's helps prevent the body from attacking a transplanted organ and reduces inflammation in joint tissues.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Azotas-75 Tablet 10's

Do not take more than the prescribed dose of Azotas-75 Tablet 10's, as it may cause serious side effects. If you suspect you have taken an overdose or notice any unusual symptoms, please consult a doctor immediately.

Drug Warnings

  • Do not take Azotas-75 Tablet 10's if you are allergic to any of its ingredients or other immunosuppressant medications.
  • Let your doctor know before taking Azotas-75 Tablet 10's if you have liver or kidney problems, serious blood disorders, immune system problems, bone marrow problems, serious infections, or immunodeficiency syndrome.
  • Do not take Azotas-75 Tablet 10's if you are pregnant or planning to become pregnant, as it may cause serious congenital disabilities in the unborn baby.
  • Avoid taking Azotas-75 Tablet 10's while breastfeeding, as it can pass into breast milk.
  • Azotas-75 Tablet 10's should not be given to children, as its safety and effectiveness have not been established.
  • Azotas-75 Tablet 10's may cause dizziness and drowsiness, so drive with caution.
  • Using Azotas-75 Tablet 10's for a long time may increase your chance of getting certain types of cancer, such as lymphoma (cancer of the spleen, thymus gland, and bone marrow), leukaemia (blood cancer), and skin cancer.
  • Avoid excessive exposure to sunlight; wear protective clothing; and apply a high-SPF sunscreen while using Azotas-75 Tablet 10's.

Diet & Lifestyle Advise

Healthy diet:

  • Eat foods rich in antioxidants, such as berries, spinach, kidney beans, and dark chocolate.
  • Consume foods containing flavonoids to help reduce inflammation, such as soy, berries, broccoli, grapes, and green tea.
  • Avoid alcohol consumption.

Physical activity and exercise:

  • Maintain a healthy weight by engaging in regular low-impact exercise and eating a healthy diet.
  • Physical activity helps strengthen muscles and relieve joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Practising yoga may also help improve joint flexibility and manage pain.

Rest and recovery:

  • Get adequate sleep, as rest can help reduce inflammation and swelling.
  • Apply cold or hot compresses to the joints for 15-20 minutes regularly to reduce swelling.

Stress management and therapies:

  • De-stress by meditating, reading, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.

Habit Forming

No

Therapeutic Class

[IMMUNOSUPPRESSANTS]

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Azotas-75 Tablet 10's. It could lead to increased dizziness and drowsiness.

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Pregnancy

Caution

Azotas-75 Tablet 10's is a Category D pregnancy drug that is not recommended for pregnant women or given only under the strict guidance of the doctor, as there is no clinical data available on use in pregnant women.

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Breast Feeding

Caution

It is not recommended to take Azotas-75 Tablet 10's while you are breastfeeding. Azotas-75 Tablet 10's passes into breast milk.

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Driving

Caution

Azotas-75 Tablet 10's may cause dizziness, drowsiness, and tiredness; do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Take Azotas-75 Tablet 10's only as prescribed by your doctor, especially if you are dealing with Liver diseases/conditions, as your doctor may adjust the dose as required.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment before taking Azotas-75 Tablet 10's.

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Children

Unsafe

Azotas-75 Tablet 10's should not be used by children below 18 years of age, as its efficacy and safety have not been established.

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Heart

Consult your doctor

Please consult your physician if you have any heart-related problems before taking Azotas-75 Tablet 10's.

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Geriatrics

Caution

Exercise caution when administering Azotas-75 Tablet 10's to geriatric patients; close monitoring is required.

FAQs

Azotas-75 Tablet 10's is used to prevent kidney transplant rejection. It is also used to treat symptoms of active rheumatoid arthritis (a condition in which the immune system attacks the joints, causing pain and inflammation).

Azotas-75 Tablet 10's causes leukopenia (decreased number of white blood cells) and hence may make you more susceptible to infections. Consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.

Azotas-75 Tablet 10's acts as an immunosuppressant, which helps in reducing inflammation and preventing joint stiffness, thereby providing relief from rheumatoid arthritis.

If you miss a dose of Azotas-75 Tablet 10's, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.

Diarrhoea might be a side effect of Azotas-75 Tablet 10's. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in your stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Azotas-75 Tablet 10's is a Category D pregnancy drug that is not recommended for pregnant women or given only under the strict guidance of the doctor, as there is no clinical data available on use in pregnant women.

Azotas-75 Tablet 10's starts to work gradually. It can take up to 12 weeks of taking the right adjusted dose before you notice any benefits.

If you miss a prescription dose, take it as soon as you recall and resume your regular routine. If you are near the next dose, skip the missing dose and resume your regular schedule. Do not take a double dose to make up for a forgotten dose.

It depends on your individual medical condition and response to the medication. Your doctor will determine the appropriate duration of treatment based on your specific needs.

Taking Azotas-75 Tablet 10's for a long time can increase your risk of developing some types of cancer, including skin cancer. As a result, avoid direct sunlight, apply sunscreen (SPF 30 or higher), and wear clothes that shield your arms and legs.

You'll have regular blood tests while taking azathioprine. These tests will ensure that any concerns or problems are found quickly.

Azotas-75 Tablet 10's may have an effect on your liver, kidneys, or bone marrow. Before you begin taking this medication, you will undergo blood tests to assess your liver function, renal function, and blood count. From week one to week eight of your treatment, you will undergo at least one blood test every week.

Yes, taking Azotas-75 Tablet 10's for a long time can increase your risk of developing some types of cancer, including skin cancer. Seek medical attention if you experience any changes in your body.

Using Cyclosporine together with Azotas-75 Tablet 10's may decrease the effects of cyclosporine. Caution is advised if Cyclosporine must be taken with Azotas-75 Tablet 10's. You may need a dose adjustment or a special test if you use both medications.

Alcohol does not affect the way azathioprine works. However, both azathioprine and alcohol can affect your liver. For this reason, limiting or avoiding the consumption of alcohol is recommended.

Common side effects of Azotas-75 Tablet 10's may include nausea, headache, vomiting, diarrhoea, unusual fatigue, dizziness, loss of appetite, increased liver enzymes, lowered resistance to infections, tingling sensation, stomach pain, leukopenia (decreased number of white blood cells), and sore throat. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

Plot No. 45, N.T.M., Sector -26, Chandigarh.
Other Info - AZO0212

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