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  3. Biomycin-250 Tablet 4's

Biomycin-250 Tablet 4's, Pack of 4
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Biomycin-250 Tablet 4's is used to treat a wide range of bacterial infections, including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection, the affected skin appears swollen and red and is typically painful and warm to the touch), and ear infections. Besides this, it is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. It contains Clarithromycin, which inhibits the growth of bacteria. It may cause some common side effects, such as nausea, diarrhoea, vomiting, loss of appetite, bloating, indigestion, headaches and difficulty sleeping. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

CLARITHROMYCIN-250MG

Manufacturer/Marketer :

German Remedies Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Biomycin-250 Tablet 4's

Biomycin-250 Tablet 4's is used to treat a wide range of bacterial infections, including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection, the affected skin appears swollen and red and is typically painful and warm to the touch), and ear infections. Besides this, Biomycin-250 Tablet 4's is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori.

Biomycin-250 Tablet 4's contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Biomycin-250 Tablet 4's helps prevent infections.

Biomycin-250 Tablet 4's should only be if your doctor has prescribed it to you. Biomycin-250 Tablet 4's should not be stopped even if you feel better as it is an antibiotic medication, and completing the full course is necessary; otherwise, the infection might reappear in a more severe form. Like all medicines, Biomycin-250 Tablet 4's may cause some common side effects, including feeling sick (nausea), diarrhoea, being sick (vomiting), loss of appetite, bloating, indigestion, headaches, and difficulty sleeping. These side effects are temporary and may get resolve after some time; however, if these side effects persists, let your doctor know about this.

Do not take Biomycin-250 Tablet 4's if allergic to azithromycin, other macrolide antibiotics, or any components present in Biomycin-250 Tablet 4's. Biomycin-250 Tablet 4's isn't normally recommended during pregnancy and while breastfeeding. But your doctor may prescribe it if the benefits of taking it are greater than the risks. Before using the Biomycin-250 Tablet 4's, tell your doctor if you ever had an allergy to Biomycin-250 Tablet 4's have kidney problems, liver problems, a swollen food pipe (oesophagitis), lupus disease (an autoimmune disease), or muscle disease (myasthenia gravis).

Uses of Biomycin-250 Tablet 4's

Biomycin-250 Tablet 4's is used in the treatment of Bacterial infections. The detailed uses of Biomycin-250 Tablet 4's are as follows:<br/> • Treatment of Respiratory Infections: Biomycin-250 Tablet 4's is commonly prescribed to treat respiratory infections such as bronchitis and pneumonia caused by susceptible bacteria.<br/> • Skin Infections: Biomycin-250 Tablet 4's effectively treats skin infections like cellulitis or impetigo, caused by bacterial pathogens.<br/> • Sinusitis: Biomycin-250 Tablet 4's is used to manage acute bacterial sinusitis, relieving symptoms like nasal congestion and facial pain caused by bacterial infections.<br/> • Otitis Media: Biomycin-250 Tablet 4's is frequently utilized to treat middle ear infections (otitis media), providing relief from ear pain and inflammation.<br/>

Directions for Use

  • Biomycin-250 Tablet 4's can be taken with or without food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Biomycin-250 Tablet 4's as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Biomycin-250 Tablet 4's is a type of macrolide class of antibiotic which is effective against a wide range of bacteria, including gram-negative and gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections, including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori). Biomycin-250 Tablet 4's is sometimes used by people who have an allergy to penicillin and antibiotics similar to penicillin, such as amoxicillin.

How Biomycin-250 Tablet 4's Works

Biomycin-250 Tablet 4's contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Biomycin-250 Tablet 4's helps prevent infections.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Biomycin-250 Tablet
  • Drink plenty of fluids and consider oral rehydration solutions.
  • Eat bland, easily digestible foods like bananas, rice, toast, and applesauce.
  • Avoid trigger foods like greasy, spicy, fatty, acidic, and caffeinated foods.
  • Gradually reintroduce fiber-rich foods as symptoms improve.
  • Get adequate sleep and rest.
  • Practice relaxation techniques to manage stress.
  • Maintain regular bowel habits.
  • Avoid overexertion and take breaks when needed.
  • Consult a doctor if your gastrointestinal symptoms are severe, persistent, or accompanied by fever, bloody stools, dehydration, or last for more than a few days.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
  • Use a warm compress on the affected area to help reduce discomfort.
  • Elevate the affected limb above heart level.
  • Remove the IV catheter (if applicable) and reinsert at a different site.
  • Consult your healthcare provider if symptoms are severe or persist.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Biomycin-250 Tablet 4's

Do not take more than the prescribed dose of Biomycin-250 Tablet 4's as it may cause overdose. The symptoms of overdose include diarrhoea, vomiting, nausea and stomach pain. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Avoid taking Biomycin-250 Tablet 4's if you are allergic to the medicine or any other components present in it. Iron and antacids (like magnesium hydroxide and aluminium hydroxide) may bind to Biomycin-250 Tablet 4's in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Biomycin-250 Tablet 4's and iron supplements and antacids. Besides this, in some cases, the use of Biomycin-250 Tablet 4's causes antibiotic-associated diarrhoea. Biomycin-250 Tablet 4's may cause sensitive skin to sunlight and ultraviolet rays, causing an exaggerated sunburn reaction. Hence, it is advisable to apply sunscreen before going outside. Its use has also been associated with an increased risk of fungal skin infections like vaginal candidiasis (thrush). Tetracycline and Biomycin-250 Tablet 4's can form a stable calcium complex in bone-forming tissue, thereby affecting the growth of fibula bones in young children and bone development in the fetus. Using a Biomycin-250 Tablet 4's with isotretinoin should be avoided as it has been reported to cause pseudotumor cerebri (increased pressure inside the brain). Long-term use of Biomycin-250 Tablet 4's may affect your blood, kidney, and liver health, so yearly diagnostic tests of these parameters is recommended.

Drug-Drug Interactions

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ClarithromycinAstemizole
Critical
ClarithromycinBepridil
Critical

Drug-Drug Interactions

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ClarithromycinAstemizole
Critical
How does the drug interact with Biomycin-250 Tablet:
When Astemizole is taken with Biomycin-250 Tablet, it can cause a decrease in the metabolism of Astemizole.

How to manage the interaction:
Taking Biomycin-250 Tablet with Astemizole is not recommended, please consult your doctor before taking it.
ClarithromycinBepridil
Critical
How does the drug interact with Biomycin-250 Tablet:
Co-administration of Bepridil with Biomycin-250 Tablet may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Biomycin-250 Tablet with Bepridil is not recommended as it can result in an interaction, it should be taken only if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinZiprasidone
Critical
How does the drug interact with Biomycin-250 Tablet:
Taking Biomycin-250 Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Biomycin-250 Tablet and Ziprasidone can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinRanolazine
Critical
How does the drug interact with Biomycin-250 Tablet:
When Ranolazine and Biomycin-250 Tablet are taken together, significantly increases the blood levels and effects of Ranolazine.

How to manage the interaction:
Co-administration of Biomycin-250 Tablet and Ranozaline can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
ClarithromycinMesoridazine
Critical
How does the drug interact with Biomycin-250 Tablet:
Co-administration of Biomycin-250 Tablet and Mesoridazine may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Biomycin-250 Tablet and Mesoridazine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinEplerenone
Critical
How does the drug interact with Biomycin-250 Tablet:
Co-administration of Eplerenone and Biomycin-250 Tablet may significantly increase the blood levels and effects of eplerenone.This may increase the risk or severity of side effects like high blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking Biomycin-250 Tablet with Eplerenone is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the Doctor's advice.
ClarithromycinColchicine
Critical
How does the drug interact with Biomycin-250 Tablet:
Coadministration of colchicine with Biomycin-250 Tablet may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Taking Colchicine with Biomycin-250 Tablet is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
ClarithromycinErgotamine
Critical
How does the drug interact with Biomycin-250 Tablet:
When Ergotamine is taken with Biomycin-250 Tablet, the amount of Ergotamine in the blood can go up.

How to manage the interaction:
Taking Biomycin-250 Tablet with Ergotamine can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinTolvaptan
Critical
How does the drug interact with Biomycin-250 Tablet:
When Tolvaptan and Biomycin-250 Tablet are taken together, may significantly increase the blood levels and effects of Tolvaptan.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Biomycin-250 Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClarithromycinQuinidine
Critical
How does the drug interact with Biomycin-250 Tablet:
When Quinidine is taken with Biomycin-250 Tablet, can increase the blood levels and effects of Quinidine. This may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Biomycin-250 Tablet and Quinidine can lead to an interaction, it can be taken if advised by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats. However, if you experience any symptoms like headache, confusion, vomiting, diarrhea, ringing in the ears, hearing loss, blurred or double vision, or sensitivity to light, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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CLARITHROMYCIN-250MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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CLARITHROMYCIN-250MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice may delay the gastrointestinal absorption of Biomycin-250 Tablet. Avoid grapefruit juice while on treatment with Biomycin-250 Tablet.

Diet & Lifestyle Advise

  • Probiotics and prebiotics can also help to reduce the side effects of antibiotics.
  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Eating grapefruit during antibiotics treatment can prevent the body from utilizing Biomycin-250 Tablet 4's properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic.
  • Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of Biomycin-250 Tablet 4's.
  • Avoid intake of alcoholic beverages with Biomycin-250 Tablet 4's as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Biomycin-250 Tablet 4's in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Biomycin-250 Tablet 4's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

Biomycin-250 Tablet 4's should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol.

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Pregnancy

Consult your doctor

Biomycin-250 Tablet 4's should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Let your doctor know if you are a nursing mother before taking Biomycin-250 Tablet 4's; your doctor will decide whether Biomycin-250 Tablet 4's can be taken by breastfeeding mothers or not.

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Driving

Consult your doctor

Not enough scientific data available for Biomycin-250 Tablet 4's, hence it is advised to consult your doctor.

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Liver

Caution

Biomycin-250 Tablet 4's to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Biomycin-250 Tablet 4's to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Biomycin-250 Tablet 4's can be given safely to children above 6 months of age, with the dose to be adjusted and recommended by a child specialist only.

Have a query?

FAQs

Biomycin-250 Tablet 4's is used to treat bacterial infections, including chest infections, skin infections, and ear infections. Besides this, Biomycin-250 Tablet 4's is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori.

Biomycin-250 Tablet 4's contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Biomycin-250 Tablet 4's helps in the prevention of infections.

You should avoid taking iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking Biomycin-250 Tablet 4's. Avoid taking any other antibiotics containing Biomycin-250 Tablet 4's unless your doctor has prescribed you.

After taking antibiotics such as Biomycin-250 Tablet 4's, some people get thrush, a fungal infection. This is due to the fact that antibiotics kill the regular, harmless bacteria that serve to protect you from thrush.

Biomycin-250 Tablet 4's treats only bacterial infections. It will not work for viral infections (such as common cold, flu).

No, Biomycin-250 Tablet 4's is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with doctor advice only.

Side-effects are rare with Biomycin-250 Tablet 4's and do not usually last long. They will get better after a day or two. if those side effects persist reach out to the doctor immediately.​

No, Biomycin-250 Tablet 4's should not be stopped even if you feel better as it is an antibiotic medication and completing the full course if very necessary; otherwise, the infection might re-appear in a more severe form.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads, Ahmedabad 380015, Gujarat, India.
Other Info - BIO2395

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 22, 2025 | 1:20 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/product/6094/smpc#gref
  2. https://www.medicines.org.uk/emc/files/pil.6094.pdf
  3. https://www.nhs.uk/medicines/clarithromycin/
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