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  3. Birafer 250 mg Tablet 120's

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Birafer 250 mg Tablet 120's, Pack of 1 TABLET
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Birafer 250 mg Tablet is an anti-androgen medicine used to treat prostate cancer. It contains Abiraterone, which is in a class of medications called androgen biosynthesis inhibitors. It works by decreasing the amount of certain hormones in the body. Common side effects of Birafer 250 mg Tablet may include nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite, and groin pain.

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Composition :

ABIRATERONE ACETATE-250MG

Manufacturer/Marketer :

Pharmafer Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Birafer 250 mg Tablet

Birafer 250 mg Tablet is an anti-androgen medicine used in the treatment of prostate cancer. It is used to treat metastatic castration-resistant prostate cancer (a condition where cancer does not get controlled with hormonal therapy) and metastatic castration-sensitive prostate cancer (a condition where cancer has spread to other parts of the body but can be controlled) in men. Prostate cancer is a condition that occurs when the prostate gland cells increase abnormally. Symptoms may include difficulty in urinating, pain, numbness, etc.

Birafer 250 mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. Birafer 250 mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. 

Birafer 250 mg Tablet may cause certain side effects such as nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite and groin pain. These side effects usually disappear without any medical attention. However, if these side effects persist, inform your doctor. Take this medicine as advised by your doctor. It should be taken on an empty stomach at least 2 hours before or after meals. Your doctor will decide the dose of the medicine based on the severity of your disease.

Birafer 250 mg Tablet should be avoided if you are allergic to it. Inform your doctor if you have any pre-existing or a history of liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention before taking Birafer 250 mg Tablet . Birafer 250 mg Tablet is not recommended for use in women and children as the safety and efficacy of this medicine are not established. Inform your doctor of all your ongoing medications to avoid interactions. This medicine is used in combination with prednisolone for the treatment of prostate cancer. 

Uses of Birafer 250 mg Tablet

Birafer 250 mg Tablet is used to treat prostate cancer. The detailed uses of Birafer 250 mg Tablet are as follows:<br/>• Manages advanced prostate cancer: Birafer 250 mg Tablet is used in combination with prednisone to treat prostate cancer that has spread to other parts of the body.<br/>• Helps lower hormone levels: Birafer 250 mg Tablet reduces the production of certain hormones that fuel the growth of prostate cancer cells.<br/>

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Directions for Use

• Birafer 250 mg Tablet can be taken on an empty stomach at least two hours before or after a meal as directed by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Birafer 250 mg Tablet as a whole with a glass of water.• Do not break, chew or crush Birafer 250 mg Tablet .

Medicinal Benefits

Birafer 250 mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes increase of cancer cells in prostate gland. Birafer 250 mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. Birafer 250 mg Tablet is used in combination with prednisolone for the treatment of prostate cancer. It is mainly intended for use in men only.

How Birafer 250 mg Tablet Works

Birafer 250 mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. Birafer 250 mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.

Storage

• Store in a cool and dry place away from sunlight.• Keep Birafer 250 mg Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Birafer 250 mg Tablet
  • If you have discomfort, illness, or unease after taking medication, seek medical attention.
  • Your treatment plan may be modified, including adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage discomfort, follow your doctor's advice, like getting plenty of rest, or staying hydrated, and practising stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to manage the discomfort effectively.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of Birafer 250 mg Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Birafer 250 mg Tablet may include fast or irregular heartbeat, lightheadedness, dizziness, or fainting, shortness of breath or difficulty breathing, swelling of the feet, ankles, or lower legs, and unexplained weight gain. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Birafer 250 mg Tablet should be avoided if you are allergic to it or any other components present in it. Inform your doctor if you have/had any conditions like liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention or taking any other medicines before taking Birafer 250 mg Tablet as it may cause serious side effects. Birafer 250 mg Tablet is not recommended for use in women and children as the safety and efficacy of this medicine are not established. This medicine is used in combination with prednisolone for the treatment of prostate cancer.

Drug-Drug Interactions

verifiedApollotooltip
AbirateroneMesoridazine
Critical
AbirateroneZiprasidone
Critical

Drug-Drug Interactions

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AbirateroneMesoridazine
Critical
How does the drug interact with Birafer 250 mg Tablet:
Taking Birafer 250 mg Tablet with Mesoridazine can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Birafer 250 mg Tablet and Mesoridazine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneZiprasidone
Critical
How does the drug interact with Birafer 250 mg Tablet:
Taking Birafer 250 mg Tablet with ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Birafer 250 mg Tablet and ziprasidone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AbirateroneSaquinavir
Critical
How does the drug interact with Birafer 250 mg Tablet:
Taking Birafer 250 mg Tablet with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Birafer 250 mg Tablet and Saquinavir together is not recommended as it can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneThioridazine
Critical
How does the drug interact with Birafer 250 mg Tablet:
Taking Birafer 250 mg Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Birafer 250 mg Tablet and Thioridazine together is not recommended and can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneEliglustat
Critical
How does the drug interact with Birafer 250 mg Tablet:
Coadministration of Birafer 250 mg Tablet with Eliglustat can increase the levels of Eliglustat in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Birafer 250 mg Tablet with Eliglustat is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AbirateroneVemurafenib
Severe
How does the drug interact with Birafer 250 mg Tablet:
Taking Birafer 250 mg Tablet with Vemurafenib can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Birafer 250 mg Tablet with Vemurafenib together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneHydrocodone
Severe
How does the drug interact with Birafer 250 mg Tablet:
Coadministration of Birafer 250 mg Tablet with Hydrocodone can increase the levels of Hydrocodone in the body. This increases the risk or severity of side effects like low blood pressure, and low respiratory rate.

How to manage the interaction:
Taking Birafer 250 mg Tablet with Hydrocodone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, difficulty concentrating, impairment in thinking and judgment, fainting, confusion, excessive drowsiness, slow heart rate, and shallow or difficult breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbirateroneCarbamazepine
Severe
How does the drug interact with Birafer 250 mg Tablet:
Taking carbamazepine and Birafer 250 mg Tablet together may reduce the blood level of Birafer 250 mg Tablet.

How to manage the interaction:
Taking carbamazepine and Birafer 250 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. Without consulting a doctor, never stop taking any medication.
AbirateronePasireotide
Severe
How does the drug interact with Birafer 250 mg Tablet:
Taking Birafer 250 mg Tablet with Pasireotide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Birafer 250 mg Tablet with Pasireotide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneIbutilide
Severe
How does the drug interact with Birafer 250 mg Tablet:
Taking Birafer 250 mg Tablet with Ibutilide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Birafer 250 mg Tablet and Ibutilide together can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to take vegetables like cauliflower, cabbage, broccoli, spinach and kale. This food slows the growth of prostate cancer and even reduces the risk of prostate cancer.
  • It is advised to consume fewer dairy products as these foods may increase the risk of prostate cancer. 
  • Physical activity helps in strengthening muscles, reduces fatigue, helps in weight loss and gives strength.
  • Maintain a healthy weight by doing regular simple exercises and yoga. 
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention. 
  • Avoid including red meat high amounts of meat in your diet. When meat is cooked, it may increase the risk of developing prostate cancer.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Birafer 250 mg Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

Interaction of Birafer 250 mg Tablet with alcohol is unknown. It is advisable to consult your doctor if you have concerns.

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Pregnancy

Not applicable

Not intended for women.

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Breast Feeding

Not applicable

Not intended for women.

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Driving

Caution

Birafer 250 mg Tablet may decrease alertness or make you feel sleepy and dizzy. So, do not drive or operate heavy machinery while taking Birafer 250 mg Tablet until your vision improves.

bannner image

Liver

Caution

Birafer 250 mg Tablet should be used with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose based on your condition.

bannner image

Kidney

Caution

Birafer 250 mg Tablet should be used with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust the dose based on your condition.

bannner image

Children

Unsafe

Birafer 250 mg Tablet is not recommended for use in children as the safety and efficacy of this medicine are not established.

FAQs

Birafer 250 mg Tablet is used to treat Prostate Cancer.

Birafer 250 mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. It works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.

No, do not stop taking Birafer 250 mg Tablet without consulting your doctor. It is recommended to take this medicine for the entire prescribed duration, even when symptoms improve or resolve.

The common side-effects of Birafer 250 mg Tablet are nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite, and groin pain. These side effects usually do not require any medical attention.

Take Birafer 250 mg Tablet as advised by your doctor. However, if you forget or miss any dose of Birafer 250 mg Tablet , take it as soon as you remember unless it is time for your next dose. But do not double the dose.

Inform your doctor if you have a pre-existing or a history of liver/kidney disease, hypoglycemia, hypokalemia, bone disorders, adrenocortical insufficiency, fluid retention and cardiovascular conditions before taking Birafer 250 mg Tablet .

Birafer 250 mg Tablet is not a cure for prostate cancer. However, it helps manage advanced stages by blocking testosterone production, thereby slowing the growth and progression of the cancer.

No, Birafer 250 mg Tablet is not a chemotherapy drug. Birafer 250 mg Tablet is a hormonal therapy that lowers testosterone levels to reduce the growth of prostate cancer.

You need to take prednisolone with Birafer 250 mg Tablet to reduce the risk of high blood pressure, fluid retention (too much water in your body), and low potassium levels in your blood which may be caused by Birafer 250 mg Tablet .

Yes, Birafer 250 mg Tablet can affect the liver. Your healthcare provider will perform blood tests to check your liver function before and during treatment.

Liver function tests (investigation) should be conducted before starting Birafer 250 mg Tablet and periodically during treatment, as advised by your healthcare provider.

Birafer 250 mg Tablet should be taken once daily on an empty stomach, at least two hours after eating or one hour before eating. Swallow Birafer 250 mg Tablet whole with a glass of water; do not chew, crush, or break it. Always follow the recommended dose.

Country of origin

India
Other Info - BIR0007

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:04 AM IST

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Reference

  1. https://www.sterisindia.com/latest-update/abiraterone-acetate-/2822
  2. https://lotusinternational.com/product/zytiga/
  3. https://www.zytiga.com/
  4. https://medlineplus.gov/druginfo/meds/a611046.html
  5. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202379s031s033lbl.pdf

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