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compositionComposition:ESOMEPRAZOLE-40MG+LEVOSULPIRIDE-75MG
prescriptionPrescription Medicine
Blupraz-L Capsule 15's

Blupraz-L Capsule 15's is used to treat gastro-oesophageal reflux disease (GERD). It contains Esomeprazole and Levosulpiride, which reduce acid production by increasing stomach and intestinal movement, and preventing the backflow of food and acid into the mouth. In some cases, you may experience certain common side effects such as headache, abdominal pain, constipation, diarrhoea, flatulence, nausea and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

ESOMEPRAZOLE-40MG+LEVOSULPIRIDE-75MG

Manufacturer/Marketer :

Blue Cross Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Nov-27

Return Policy :

Not Returnable

About Blupraz-L Capsule 15's

Blupraz-L Capsule 15's is used to treat gastro-oesophageal reflux disease (GERD). Gastroesophageal reflux disease occurs when stomach acid frequently flows back into the food pipe (oesophagus); this causes acidity, pain and heartburn.

Blupraz-L Capsule 15's contains Esomeprazole and Levosulpiride. Esomeprazole works by preventing the production of stomach acid. Levosulpiride works by increasing the stomach and intestinal movement and preventing the backflow of food and acid into the mouth.

In some cases, you may experience certain common side effects such as headache, abdominal pain, constipation, diarrhoea, flatulence, nausea and vomiting. You are advised to talk to your doctor if you experience these side effects persistently.

Before taking this medicine, you should tell your doctor if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Blupraz-L Capsule 15's should not be given to children as safety has not been established.

Uses of Blupraz-L Capsule 15's

Blupraz-L Capsule 15's is used to treat acid-related stomach disorders. The detailed uses of Blupraz-L Capsule 15's are as follows:

  • Gastro-oesophageal reflux disease (GERD): Blupraz-L Capsule 15's is used to treat acid reflux, heartburn, and irritation of the food pipe (oesophagus).
  • Acidity: Blupraz-L Capsule 15's helps to reduce excessive stomach acid production and related discomfort.
  • Heartburn: Blupraz-L Capsule 15's treats the burning sensation in the chest due to acid reflux.
  • Peptic ulcers: Blupraz-L Capsule 15's helps in the healing of ulcers in the stomach and upper intestine by lowering acid production.
  • Indigestion: Blupraz-L Capsule 15's improves digestion by reducing acid and promoting normal stomach movement.

Key Benefits

  • Blupraz-L Capsule 15's belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD).
  • Esomeprazole (proton pump inhibitor) works by blocking the action of an enzyme called the gastric proton pump, which is responsible for the production of acid.
  • Levosulpiride (prokinetic agent) works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth.
  • Blupraz-L Capsule 15's helps in preventing acid reflux, thereby providing relief from acidity and heartburn.
Side effects of Blupraz-L Capsule
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Directions for Use

  • Blupraz-L Capsule 15's should be taken 1 hour before a meal, preferably in the morning.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow Blupraz-L Capsule 15's as a whole with a glass of water.
  • Do not crush, break, or open it.

How Blupraz-L Capsule 15's Works

Blupraz-L Capsule 15's contains Esomeprazole and Levosulpiride. Esomeprazole works by blocking the action of an enzyme called the gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Blupraz-L Capsule 15's helps in preventing acid reflux, thereby providing relief from acidity and heartburn.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Blupraz-L Capsule 15's. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

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Pregnancy

Unsafe

Blupraz-L Capsule 15's should not be taken if you are pregnant. Consult your doctor before taking Blupraz-L Capsule 15's if you are pregnant.

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Breast Feeding

Unsafe

Blupraz-L Capsule 15's may pass into breast milk. Consult your doctor before taking Blupraz-L Capsule 15's if you are breastfeeding.

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Driving

Caution

Blupraz-L Capsule 15's may cause dizziness, drowsiness and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Unsafe

Blupraz-L Capsule 15's should not be used in patients with hepatic impairment. Consult your doctor before taking Blupraz-L Capsule 15's if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Blupraz-L Capsule 15's if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Blupraz-L Capsule 15's should not be given to children as the safety and effectiveness were not established.

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Heart

Caution

Blupraz-L Capsule 15's should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems.

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Geriatrics

Caution

Blupraz-L Capsule 15's should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Blupraz-L Capsule 15's.

What if I have taken an overdose of Blupraz-L Capsule 15's

Do not take more than the prescribed dose of Blupraz-L Capsule 15's as it may cause severe side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight through regular exercise.
  • Avoid lying down after eating, as it causes acid reflux.
  • Avoid tight-fitting clothes as they might increase the pressure on the abdomen, leading to acid reflux.
  • Practice relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
  • Avoid sitting continuously, as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Have a query?

How Soon It Starts Working

  • The time required for Blupraz-L Capsule 15's to start to work: Blupraz-L Capsule 15's ideally shows its action within a few hours after administration.
  • The time for which the effects of Blupraz-L Capsule 15's last: The duration of action for Blupraz-L Capsule 15's is not clinically established.

What if you forget to take Blupraz-L Capsule 15's

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and follow your regular dosing schedule. Do not take a double dose to make up for your missed dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Blupraz-L Capsule 15's if you are allergic to any of its contents, if you are taking nelfinavir (anti-HIV), if you have a gastrointestinal haemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment.
  • Inform your doctor before taking Blupraz-L Capsule 15's if you have severe liver or kidney problems; if you are due to have a Chromogranin A test; if you experience unexplained weight loss, stomach pain, indigestion, vomiting food or blood, or if you pass black stools.
  • On long-term treatment, Blupraz-L Capsule 15's may increase the risk of bone fractures.
  • Do not take Blupraz-L Capsule 15's if you are pregnant or breastfeeding.
  • Blupraz-L Capsule 15's may cause dizziness and drowsiness, so drive only if you are alert.
  • Blupraz-L Capsule 15's should not be given to children as safety has not been established.
  • Avoid consuming alcohol along with Blupraz-L Capsule 15's as it could lead to increased drowsiness and can elevate the production of stomach acid.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Blupraz-L Capsule 15's may interact with painkillers (aspirin, naproxen), anti-HIV (atazanavir), blood thinner (clopidogrel, warfarin, cilostazol), anti-fungal (ketoconazole, itraconazole, voriconazole), anti-cancer (erlotinib, methotrexate), anti-depressant (citalopram, imipramine, clomipramine, duloxetine), anti-anxiety (diazepam), anti-convulsant (phenytoin), gastroprokinetic agent (cisapride), a drug used to treat heart problems (digoxin), immunosuppressant (tacrolimus), anti-tuberculosis (rifampicin).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interaction: Inform your doctor if you have epilepsy, mania, Clostridium difficile-associated diarrhoea (CDAD), liver disease, bone fractures, or hypomagnesemia (low levels of magnesium).

EsomeprazoleRilpivirine
Critical
EsomeprazoleNelfinavir
Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Blupraz-L Capsule:
Blupraz-L Capsule may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Blupraz-L Capsule with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
EsomeprazoleNelfinavir
Severe
How does the drug interact with Blupraz-L Capsule:
Taking nelfinavir with Blupraz-L Capsule may decrease the effects of nelfinavir.

How to manage the interaction:
Although taking Blupraz-L Capsule and Nelfinavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
EsomeprazoleClopidogrel
Severe
How does the drug interact with Blupraz-L Capsule:
Coadministration of Clopidogrel with Blupraz-L Capsule may reduce the effectiveness of clopidogrel.

How to manage the interaction:
Taking clopidogrel and Blupraz-L Capsule together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleDacomitinib
Severe
How does the drug interact with Blupraz-L Capsule:
Blupraz-L Capsule can make Dacomitinib less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Blupraz-L Capsule with Dacomitinib can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazolePazopanib
Severe
How does the drug interact with Blupraz-L Capsule:
Blupraz-L Capsule decreases the absorption of Pazopanib. This results in reduced efficacy of Pazopanib.

How to manage the interaction:
Although taking Blupraz-L Capsule and Pazopanib can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
EsomeprazoleCitalopram
Severe
How does the drug interact with Blupraz-L Capsule:
Combining Blupraz-L Capsule with Citalopram can increase the risk of irregular heart rhythm. .

How to manage the interaction:
Co-administration of Blupraz-L Capsule with Citalopram can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, it's important to contact your doctor immediately. Do not stop using any medications without a doctor's advice.
EsomeprazoleAtazanavir
Severe
How does the drug interact with Blupraz-L Capsule:
Blupraz-L Capsule reduces the absorption of atazanavir, resulting in reduced efficacy of atazanavir.

How to manage the interaction:
Although there is a possible interaction between Blupraz-L Capsule and atazanavir, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
EsomeprazoleDasatinib
Severe
How does the drug interact with Blupraz-L Capsule:
Using Dasatinib together with Blupraz-L Capsule may decrease the levels of Dasatinib.

How to manage the interaction:
Although taking Blupraz-L Capsule together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
EsomeprazoleGefitinib
Severe
How does the drug interact with Blupraz-L Capsule:
Taking gefitinib with Blupraz-L Capsule may reduce the effectiveness of gefitinib.

How to manage the interaction:
Although taking Blupraz-L Capsule and Gefitinib together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Gefitionib 12 hours before or after taking Blupraz-L Capsule. Do not stop taking any medications without consulting a doctor.
EsomeprazoleMethotrexate
Severe
How does the drug interact with Blupraz-L Capsule:
Co-administration of methotrexate and Blupraz-L Capsule can increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although taking Blupraz-L Capsule with Methotrexate can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[GASTROINTESTINAL AGENTS]

FAQs

Blupraz-L Capsule 15's is used to treat gastro-oesophageal reflux disease (GERD). Gastroesophageal reflux disease occurs when stomach acid frequently flows back into the food pipe (oesophagus); this causes acidity, pain and heartburn.

Blupraz-L Capsule 15's is a combination of two drugs, namely: Esomeprazole and Levosulpiride. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Blupraz-L Capsule 15's helps in preventing acid reflux, thereby providing relief from acidity.

Diarrhoea might be a side effect of Blupraz-L Capsule 15's. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not take Blupraz-L Capsule 15's with nelfinavir (a drug used to treat HIV infections). Consult your doctor before taking Blupraz-L Capsule 15's with other medications to avoid potential side effects.

Blupraz-L Capsule 15's contains esomeprazole, which might increase the risk of fracture in the wrist, hip or spine. This mainly occurs in people taking Blupraz-L Capsule 15's for longer durations. Inform your doctor if you have osteoporosis or if you are taking corticosteroids; your doctor may prescribe calcium and vitamin D supplements.

Blupraz-L Capsule 15's may cause changes in blood tests for checking liver functioning. Inform the person doing the tests that you are taking Blupraz-L Capsule 15's.

Dry mouth could be a side effect of Blupraz-L Capsule 15's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy may help stimulate saliva and thereby prevent mouth dryness.

Blupraz-L Capsule 15's works by relieving the symptoms such as heartburn, stomach pain, or irritation. It also neutralises the acid production in the stomach to prevent discomfort.

Blupraz-L Capsule 15's contains Esomeprazole and Levosulpiride.

The usual recommendation is to take it one hour before the meal, preferably in the morning.

Yes, Blupraz-L Capsule 15's may cause dizziness and drowsiness, so drive or operate machinery only if you are alert.

Yes, it can help to ease stomach pain.

Store Blupraz-L Capsule 15's according to the instructions on the leaflet, away from sunlight, at a temperature not exceeding 25°C. Dispose of unused medicine. Keep it out of reach of pets and children.

Blupraz-L Capsule 15's is usually taken in the morning, one hour before the food, or as directed by the physician.

Blupraz-L Capsule 15's is contraindicated for use if you are allergic to any of its contents, if you are taking nelfinavir (anti-HIV), if you have a gastrointestinal haemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment. It is also contraindicated for use in pregnant and breastfeeding women.

Blupraz-L Capsule 15's might increase the risk of wrist, hip or spine fracture. This mainly occurs in individuals taking Blupraz-L Capsule 15's for extended periods.

Common side effects of Blupraz-L Capsule 15's may include headache, abdominal pain, constipation, diarrhea, flatulence, nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Blupraz-L Capsule 15's should not be given to children as safety and effectiveness have not been established.

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Author Details

Santoshini Reddy GDoctor badge

Written By

  • Santoshini Reddy G

    M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

  • Bayyarapu Mahesh Kumar

    M Pharmacy

Last Updated

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Country of origin

India

Manufacturer/Marketer address

Peninsula Chambers, Peninsula Corporate Park, G.K Marg, Lower Parel (West), Mumbai - 400013, Maharashtra, India.
Other Info - BLU0261
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