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  3. Brivex Eye Drops 5 ml

Brivex Eye Drops 5 ml, Pack of 1 EYE DROPS
Brivex Eye Drops 5 ml, Pack of 1 EYE DROPS
Brivex Eye Drops 5 ml, Pack of 1 EYE DROPS
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Composition :

BRIMONIDINE-0.2%W/V + BRINZOLAMIDE-1%W/V

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

OPHTHALMIC

Return Policy :

Not Returnable

Expires on or after :

About Brivex Eye Drops 5 ml

Brivex Eye Drops 5 ml is indicated for lowering high intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Glaucoma is an eye disease that causes damage to the optic nerve and results in reduced vision. Ocular hypertension is increased pressure in the eye due to poor drainage of aqueous humour (fluid in the eye that maintains normal pressure by its continuous flow). 
 
Brivex Eye Drops 5 ml is a combination of two drugs: Brinzolamide (carbonic anhydrase inhibitor) and Brimonidine (alpha-2 adrenergic receptor agonist). Brivex Eye Drops 5 ml decreases the production of aqueous humour, thereby helping lower the increased pressure in the eye. 
 
In some cases, you may experience certain common side effects such as blurred vision, eye redness, discomfort, drowsiness and bad taste in the mouth. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult a doctor if you are pregnant or breastfeeding. Brivex Eye Drops 5 ml is not recommended for children below 18 years as the safety and effectiveness have not been established. Brivex Eye Drops 5 ml might cause dizziness, drowsiness, and abnormal/blurred vision, so drive only if you have clear vision. Avoid touching the tip of the dropper as it may contaminate the contents.

Directions for Use

• Brivex Eye Drops 5 ml is for ophthalmic (for eye) use only.• It is recommended to apply one drop of Brivex Eye Drops 5 ml thrice daily or as prescribed by your doctor.• Check the label for directions before using this medication.• Lie down and tilt your head backward. Gently pull your lower eyelid with your index finger to form a pocket. Instil the prescribed number of drops into the pocket. Close your eyes for 1-2 minutes.• Replace the cap tightly after each use. • Avoid touching the container tip to the eye or eyelids to prevent contamination.

Medicinal Benefits

Brivex Eye Drops 5 ml is a combination of two drugs: Brinzolamide (carbonic anhydrase inhibitors) and Brimonidine (alpha-2 adrenergic receptor agonists). Brivex Eye Drops 5 ml is indicated for lowering high intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Brivex Eye Drops 5 ml decreases the production of aqueous humour, thereby helping lower the increased pressure in the eye. 

How Brivex Eye Drops 5 ml Works

Brivex Eye Drops 5 ml is a combination of two drugs: Brinzolamide (carbonic anhydrase inhibitor) and Brimonidine (alpha-2 adrenergic receptor agonist). Brivex Eye Drops 5 ml decreases the production of aqueous humour, thereby helping lower the increased pressure in the eye.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Brivex Eye Drops 5 ml

Use Brivex Eye Drops 5 ml only as prescribed by the physician. It is advised not to exceed the recommended dose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not take Brivex Eye Drops 5 ml if you are allergic to any of its components, if you are taking monoamine oxidase inhibitors, antidepressants, if you have severe kidney problems or excess acidity in the blood. Inform your doctor if you have liver problems, narrow-angle glaucoma, dry eyes, cornea problems, coronary heart disease, depression, poor or disturbed blood circulation. Consult a doctor before using Brivex Eye Drops 5 ml if you are pregnant or breastfeeding. Brivex Eye Drops 5 ml is not recommended for children below 18 years as safety and effectiveness have not been established. Brivex Eye Drops 5 ml might cause dizziness, drowsiness, abnormal/blurred vision; so, drive only if you are alert.

Drug-Drug Interactions

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BrinzolamideDiflunisal
Severe
BrinzolamideSodium salicylate
Severe

Drug-Drug Interactions

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BrinzolamideDiflunisal
Severe
How does the drug interact with Brivex Eye Drops 5 ml:
Coadministration of Brivex Eye Drops 5 ml with diflunisal can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Brivex Eye Drops 5 ml should be used with diflunisal only if prescribed by the doctor. Consult a doctor if you experience vomiting, headache, dizziness, or fever. Do not stop using any medications without first talking to your doctor.
BrinzolamideSodium salicylate
Severe
How does the drug interact with Brivex Eye Drops 5 ml:
Concomitant use of Brivex Eye Drops 5 ml with sodium salicylate may cause ringing in the ears, nausea, vomiting, headache, dizziness, confusion, hallucinations, rapid breathing, fever, and seizure (convulsions).

How to manage the interaction:
Although there is an interaction, Brivex Eye Drops 5 ml should be used with sodium salicylate only if prescribed by the doctor. However, if you experience ringing in the ears, vomiting, headache, dizziness, or fever, contact your doctor immediately. Do not stop using any medications without consulting your doctor.
BrinzolamideCholine salicylate
Severe
How does the drug interact with Brivex Eye Drops 5 ml:
Taking Brivex Eye Drops 5 ml with Choline salicylate may increase the risk of side effects.

How to manage the interaction:
Although taking Brivex Eye Drops 5 ml and Choline salicylate together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience ringing in your ears, headache, vomiting, dizziness, or palpitations, consult a doctor. Do not stop using any medications without consulting a doctor.
BrinzolamideAspirin
Severe
How does the drug interact with Brivex Eye Drops 5 ml:
Coadministration of Brivex Eye Drops 5 ml with Aspirin may cause side effects.

How to manage the interaction:
Although there is a possible interaction between aspirin and Brivex Eye Drops 5 ml, you can take these medicines together if prescribed by a doctor. However, if you experience ringing in your ears, headache, vomiting, dizziness, or palpitations, please contact a doctor. Do not stop using any medications without talking to a doctor.
BrinzolamideSalsalate
Severe
How does the drug interact with Brivex Eye Drops 5 ml:
Concomitant use of Brivex Eye Drops 5 ml with salsalate can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Brivex Eye Drops 5 ml should be used with salsalate only if prescribed by the doctor. Consult a doctor immediately if you experience ringing in the ears, vomiting, headache, dizziness, and fever. Do not stop using any medications without first talking to your doctor.
BrimonidineBrivaracetam
Moderate
How does the drug interact with Brivex Eye Drops 5 ml:
Brivex Eye Drops 5 ml may be absorbed into the bloodstream and occasionally produce central nervous system side effects such as dizziness, drowsiness, and difficulty concentrating. Concomitant use of brivaracetam with Brivex Eye Drops 5 ml may increase the risk of these side effects.

How to manage the interaction:
Although there is an interaction brivaracetam can be taken with Brivex Eye Drops 5 ml if prescribed by the doctor. Consult the prescriber if you notice dizziness, drowsiness, and difficulty concentrating.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include fresh fruits and vegetables in your diet.

  • Avoid smoking and alcohol consumption.

  • Avoid intake of baked foods such as cakes, cookies, doughnuts or fried items such as French fries and stick margarine as these foods may worsen glaucoma and damage the optic nerve.

  • Cut down your coffee intake as it may increase pressure in the eye. Replace coffee with green tea.

  • Avoid exercises such as any position where the head is lower than the body, like an inverted yoga pose, as it may increase pressure in the eye. Doing selective exercises is advised for glaucoma patients.

Habit Forming

No

Therapeutic Class

ANTIGLAUCOMA AGENTS

Brivex Eye Drops 5 ml Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid consuming alcohol while using Brivex Eye Drops 5 ml as it might cause increased dizziness and drowsiness. Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Brivex Eye Drops 5 ml belongs to pregnancy category C. Use effective contraception while using Brivex Eye Drops 5 ml. Avoid using Brivex Eye Drops 5 ml during pregnancy unless clearly indicated by the doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Brivex Eye Drops 5 ml might pass into breastmilk. Avoid breastfeeding while using Brivex Eye Drops 5 ml.

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Driving

Unsafe

Brivex Eye Drops 5 ml might cause dizziness, drowsiness, and blurred/abnormal vision. So, avoid driving or operating machinery until your vision is clear.

bannner image

Liver

Caution

Please consult your doctor if you have any concerns regarding the usage of Brivex Eye Drops 5 ml in patients with liver impairment.

bannner image

Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of Brivex Eye Drops 5 ml in patients with kidney impairment. Brivex Eye Drops 5 ml is not recommended for patients with severe kidney disease.

bannner image

Children

Unsafe

Brivex Eye Drops 5 ml is not recommended for children below 18years as the safety and effectiveness have not been established.

Have a query?

FAQs

Brivex Eye Drops 5 ml is used to lower high intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

Brivex Eye Drops 5 ml decreases the production of aqueous humour, thereby helps lower the increased pressure in the eye.

Continue using Brivex Eye Drops 5 ml for as long as your doctor has prescribed it to you. Consult the doctor if irritation occurs or worsens.

Brivex Eye Drops 5 ml might cause blurred or abnormal vision. So, avoid driving or operating machinery until your vision is clear to prevent any mishappening.

Do not wear contact lens while using Brivex Eye Drops 5 ml. Remove contact lenses before using Brivex Eye Drops 5 ml and put them back 15minutes after using Brivex Eye Drops 5 ml.

Dry mouth could be a side-effect of Brivex Eye Drops 5 ml. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol; drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Brivex Eye Drops 5 ml can be used with other eye medications if prescribed by the doctor. However, maintain a gap of 5-10minutes between Brivex Eye Drops 5 ml and other eye medications.

Brivex Eye Drops 5 ml may cause common side effects such as blurred vision, eye redness, discomfort, drowsiness, and a bad taste in the mouth. In most cases, these side effects are temporary and don't require medical attention, resolving on their own over time. However, if you experience persistent side effects, it's best to consult your doctor for guidance.

Yes, Brivex Eye Drops 5 ml requires a prescription. It is a combination of brinzolamide and brimonidine, used to treat elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

Brivex Eye Drops 5 ml is not recommended for individuals allergic to its components, those taking monoamine oxidase inhibitors or antidepressants, and people with severe kidney problems or excess acidity in the blood. Additionally, children under 18 years old should not take Brivex Eye Drops 5 ml, as its safety and effectiveness have not been established. If you have liver problems, narrow-angle glaucoma, dry eyes, cornea problems, coronary heart disease, depression, or poor blood circulation, inform your doctor before taking pramipexole.

Lie down and tilt your head backwards. Gently pull your lower eyelid with your index finger to form a pocket. Instil the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.

Brivex Eye Drops 5 ml is not recommended for use during pregnancy and breastfeeding unless prescribed by the doctor. The risks and benefits should be carefully discussed with your doctor before using this medication.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Other Info - BRI0386

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

May 20, 2025 | 6:18 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.3290.pdf
  2. https://www.ema.europa.eu/en/documents/product-information/simbrinza-epar-product-information_en.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/204251s000lbl.pdf
  4. https://www.drugs.com/mtm/brimonidine-and-brinzolamide-ophthalmic.html

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