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  3. Cabazirix 60 mg Injection 6 ml

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Cabazirix 60 mg Injection 6 ml, Pack of 1 Injection
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

It is used to treat advanced prostate cancer or metastatic prostate cancer. It contains Cabazitaxel, a microtubule receptor blocker (inhibitor). Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide. Sometimes, Cabazirix 60 mg Injection 6 ml may cause side effects such as being sick (vomiting), neutropenia (lower-than-normal levels of neutrophils), low blood cell count, diarrhoea, vomiting, constipation, asthenia (abnormal weakness), pyrexia (fever), dyspnea (shortness of breath), altered taste, cough, pain in the joint, and alopecia (hair loss).

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Composition :

CABAZITAXEL-60MG

Manufacturer/Marketer :

Therdose Pharma Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Cabazirix 60 mg Injection 6 ml

Cabazirix 60 mg Injection 6 ml belongs to a group of medicines known as microtubule inhibitors. It is used to treat advanced prostate cancer or metastatic prostate cancer that has already been treated with other medications. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs. Prostate cancer is a type of cancer that only occurs in men and affects the prostate gland, a tiny gland under the bladder that produces semen.

Cabazirix 60 mg Injection 6 ml contains Cabazitaxel, a microtubule receptor blocker (inhibitor). Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.

Cabazirix 60 mg Injection 6 ml should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents. Sometimes, you may experience common side effects, such as being sick (vomiting), neutropenia (lower-than-normal levels of neutrophils), low blood cell count, diarrhoea, vomiting, constipation, asthenia (abnormal weakness), pyrexia (fever), dyspnea (shortness of breath), altered taste, cough, pain in the joint, and alopecia (hair loss). Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor.

Cabazitaxel is only for use in men. Men using this Cabazirix 60 mg Injection 6 ml must use effective birth control whenever they have sex during your treatment and four months after their final dose. Women should not take this medication, especially if they are or may become pregnant or are breast-feeding. Cabazitaxel injection may result in a substantial or life-threatening decrease in the number of white blood cells (a kind of blood cell needed to fight infection) in your blood. This increases your chances of developing a serious infection. Inform your doctor if you are 65 or older if you have or have ever had a low number of white blood cells associated with a fever if you have had radiation therapy, or if you are unable to eat a nutritious diet. Before and during treatment, your doctor will conduct laboratory tests to determine the quantity of white blood cells in your blood. If you have a low white blood cell count, your doctor may reduce your dose or stop or postpone your therapy. If your white blood cell count drops, your doctor may prescribe a prescription to help prevent life-threatening problems.

Uses of Cabazirix 60 mg Injection 6 ml

Cabazirix 60 mg Injection 6 ml is used in the treatment of Prostate cancer. The detailed uses of Cabazirix 60 mg Injection 6 ml are as follows:

  • Metastatic prostate cancer: Cabazirix 60 mg Injection 6 ml is used in combination with prednisone to treat metastatic castration-resistant prostate cancer (mCRPC), a form of prostate cancer that continues to progress despite hormone therapy. It is typically prescribed when the cancer has stopped responding to other treatments like docetaxel.
  • Chemotherapy-resistant cases: Cabazirix 60 mg Injection 6 ml is used when previous chemotherapy regimens have failed. It works by disrupting the microtubule network within cancer cells, which is essential for cell division, thereby slowing or stopping the growth of cancer.
  • Advanced-stage disease management: Cabazirix 60 mg Injection 6 ml is used to improve survival and manage symptoms in patients with advanced prostate cancer, helping to reduce pain and delay disease progression.

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Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Cabazirix 60 mg Injection 6 ml will be administered by a doctor or nurse in a healthcare facility.
  • Do not self-administer.

Medicinal Benefits

Cabazirix 60 mg Injection 6 ml contains Cabazitaxel, which belongs to a group of medicines known as microtubule inhibitors. Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.

How Cabazirix 60 mg Injection 6 ml Works

Cabazirix 60 mg Injection 6 ml contains Cabazitaxel, a microtubule receptor blocker (inhibitor). Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.

Storage

• Store in a cool and dry place away from sunlight.• Keep Cabazirix 60 mg Injection 6 ml out of reach and sight of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC.
Side effects of Cabazirix 60 mg Injection 6 ml
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Cabazirix 60 mg Injection 6 ml

As Cabazirix 60 mg Injection 6 ml is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Cabazirix 60 mg Injection 6 ml may cause sore throat, cough, fever, chills, muscle aches, burning on urination, or other signs of infection, unusual bruising or bleeding, pale skin, shortness of breath, excessive tiredness or weakness, nausea, vomiting, and diarrhoea.

Drug Warnings

Before taking the Cabazirix 60 mg Injection 6 ml, let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. White blood cells protect the body from infection. This medication may cause a decrease in the amount of white blood cells in your blood (neutropenia). You are more prone to catching an infection if your white blood cell count is low. When the quantity of white blood cells is too low, an infection can be deadly. It is critical to treat any infection as quickly as possible. Make an immediate call to the hospital. Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant. Cabazitaxel injection can produce severe or life-threatening allergic reactions, especially during the first two infusions. Your doctor will give you drugs to prevent an allergic response at least 30 minutes before the Cabazitaxel injection. You should receive your infusion in a medical institution where you may be treated swiftly if you develop an allergic reaction.

Drug-Drug Interactions

verifiedApollotooltip
CabazitaxelBaricitinib
Severe
CabazitaxelEtanercept
Severe

Drug-Drug Interactions

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CabazitaxelBaricitinib
Severe
How does the drug interact with Cabazirix 60 mg Injection 6 ml:
Coadministration of baricitinib and abatacept can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with abatacept if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
CabazitaxelEtanercept
Severe
How does the drug interact with Cabazirix 60 mg Injection 6 ml:
When Etanercept is used with Cabazirix 60 mg Injection 6 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Cabazirix 60 mg Injection 6 ml and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
CabazitaxelInfliximab
Severe
How does the drug interact with Cabazirix 60 mg Injection 6 ml:
When Cabazirix 60 mg Injection 6 ml is taken with Infliximab, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Cabazirix 60 mg Injection 6 ml with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination contact a doctor right away. Do not discontinue any medications without consulting a doctor.
CabazitaxelLeflunomide
Severe
How does the drug interact with Cabazirix 60 mg Injection 6 ml:
The use of leflunomide together with Cabazirix 60 mg Injection 6 ml may raise the risk of severe infections.

How to manage the interaction:
Taking Cabazirix 60 mg Injection 6 ml with Leflunomide together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like infection, sore throat, diarrhea, muscle pain, weight loss, fever, or difficulty breathing, contact your doctor immediately. If you experience any discomfort or burning while urinating, let your doctor know. Do not stop using any medications without talking to your doctor.
CabazitaxelTofacitinib
Severe
How does the drug interact with Cabazirix 60 mg Injection 6 ml:
Using tofacitinib together with Cabazirix 60 mg Injection 6 ml may increase the risk of serious infections.

How to manage the interaction:
Taking Cabazirix 60 mg Injection 6 ml with Tofacitinib together can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
CabazitaxelClozapine
Severe
How does the drug interact with Cabazirix 60 mg Injection 6 ml:
Co-administering clozapine with Cabazirix 60 mg Injection 6 ml may increase the risk of neutropenia.

How to manage the interaction:
Although taking Cabazirix 60 mg Injection 6 ml and Clozapine together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these symptoms - such as a severe infection, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain while urinating - contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Cabazirix 60 mg Injection 6 ml.

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Pregnancy

Unsafe

-

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Breast Feeding

Unsafe

-

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Driving

Caution

Cabazirix 60 mg Injection 6 ml may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.

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Liver

Caution

The safety of Cabazirix 60 mg Injection 6 ml has not been evaluated in patients with liver impairment. Inform your doctor before receiving the Cabazirix 60 mg Injection 6 ml if you have had a Liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Kidney failure may occur with Cabazirix 60 mg Injection 6 ml because of severe infection, loss of too much body fluid (dehydration), and other factors, and may result in death. Your doctor will examine you for this condition and, if necessary, treat you.

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Children

Unsafe

The safety and effectiveness of Cabazirix 60 mg Injection 6 ml in pediatric patients have not been established.

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Heart

Exercise caution before using Cabazirix 60 mg Injection 6 ml in case of heart problems. Please consult your doctor if you have any concerns.

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Geriatrics

Caution

Cabazirix 60 mg Injection 6 ml should be used with caution in elderly patients, as it may increase the risk of dizziness and other side effects.

FAQs

Cabazirix 60 mg Injection 6 ml is used to treat Prostate cancer.

Cabazirix 60 mg Injection 6 ml contains Cabazitaxel, a microtubule receptor blocker (inhibitor). Cabazitaxel shrinks tumours by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.

Based on the medical condition, Cabazirix 60 mg Injection 6 ml may be given alone or with other medicines used to treat Prostate cancer.

Cabazirix 60 mg Injection 6 ml is only for use in men. Women should not take this medication, especially if they are or may become pregnant or are breast-feeding.

You may not be able to get your partner pregnant after treatment with this drug. If you plan to have a baby, consult your doctor before beginning treatment. You might be able to store sperm before starting treatment.

Cabazitaxel, a prostate cancer medication, is used to treat prostate cancer.

No, it is unsafe to father a child while taking Cabazirix 60 mg Injection 6 ml. It is recommended for sexually active men to use condoms while on treatment and for at least four months after their last dose of Cabazirix 60 mg Injection 6 ml.

Cabazirix 60 mg Injection 6 ml can cause a significant decrease in the number of blood cells and platelets. Your doctor may suggest laboratory tests before and during the treatment. Tell your healthcare provider if you develop a fever or have signs of bruising or bleeding.

It is not a vesicant. Cabazirix 60 mg Injection 6 ml is a chemotherapeutic drug, used in the treatment of prostate cancer.

The common side effects of Cabazirix 60 mg Injection 6 ml may include being sick (vomiting), neutropenia (lower-than-normal levels of neutrophils), low blood cell count, diarrhoea, vomiting, constipation, asthenia (abnormal weakness), pyrexia (fever), dyspnea (shortness of breath), altered taste, cough, pain in the joint, and alopecia (hair loss). Most of these side effects may gradually resolve over time. However, if the side effects persist or worsen, consult your doctor immediately.

Country of origin

India

Manufacturer/Marketer address

Plot No'S : 118 - 120, Road No.6, Aleap Ie, Pragathi Nagar, Gajularamaram Village, Kukatpally, Hyderabad ,Telangana - 500 072, India.
Other Info - CAB0056

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 18, 2025 | 11:51 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/cabazitaxel
  2. https://medlineplus.gov/druginfo/meds/a611009.html
  3. https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/cabazitaxel
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/201023lbl.pdf
  5. https://www.jevtana.com/
  6. https://www.nhs.uk/conditions/prostate-cancer/
  7. https://www.drugs.com/drug-interactions/cabazitaxel-index.html?filter=3

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