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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Cadiquis 2.5 Tablet is used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung). Additionally, it is used to prevent blood clots in patients with atrial fibrillation (irregular heartbeat). It contains Apixaban, which works by inhibiting the action of blood clotting factor and prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein). Thus, it helps in preventing blood clot formation. Some people may experience side effects such as nausea, anaemia (lack of blood), and unusual bleeding, including swelling and bruising. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Whats That

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Composition :

APIXABAN-2.5MG

Manufacturer/Marketer :

Cadillac Lifesciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Cadiquis 2.5 Tablet

Cadiquis 2.5 Tablet is used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung). Additionally, Cadiquis 2.5 Tablet is used to prevent blood clots in patients with atrial fibrillation (irregular heartbeat). Deep vein thrombosis is a condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. Atrial fibrillation is a condition that causes irregular, often fast heartbeat.

Cadiquis 2.5 Tablet contains Apixaban, which works by inhibiting the action of blood clotting factor (X a), which is an important element of blood clotting. Thereby, it prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein) and helps in preventing blood clot formation.

Take Cadiquis 2.5 Tablet as prescribed. Your doctor will advise you how often you take Cadiquis 2.5 Tablet based on your medical condition. Some people may experience nausea, anaemia (lack of blood), and unusual bleeding, including swelling and bruising. Most of these side effects of Cadiquis 2.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Cadiquis 2.5 Tablet or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, you are advised to consult a doctor before using Cadiquis 2.5 Tablet . If you have a stomach ulcer, recent bleeding in the brain, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Cadiquis 2.5 Tablet . Your doctor may suggest a blood test called the 'international normalized ratio' (INR) to check how quickly your blood is clotting. This test result will help your doctor to decide exactly when you should start taking Cadiquis 2.5 Tablet .

Uses of Cadiquis 2.5 Tablet

Treatment of Prevention of blood clot.

Directions for Use

Take Cadiquis 2.5 Tablet with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not chew or break it. If you have difficulty swallowing the whole tablet, crush it and mix it with water, 5 % dextrose in water, apple puree, or juice.

Medicinal Benefits

Cadiquis 2.5 Tablet is primarily used to prevent and treat blood clots in the body by inhibiting the action of clotting factor Xa, which is an important element of blood clotting. Thereby, it prevents the conversion of fibrinogen to fibrin (a protein that binds platelets together and forms a clot) and helps in preventing blood clot formation.

How Cadiquis 2.5 Tablet Works

Cadiquis 2.5 Tablet contains Apixaban, which works by inhibiting the action of blood clotting factor (X a), which is an important element of blood clotting. Thereby, it prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein) and helps in preventing blood clot formation.

Storage

Store in a cool and dry place away from sunlight
Side effects of Cadiquis 2.5 Tablet
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Stay hydrated by taking fluids like water, juices and soups etc.
  • Eat fruits and vegetables which contain vitamins.
  • Take iron rich food like dry fruits, green leafy vegetables and sea food etc.
  • Reduce intake of milk, cheese, yogurt, soy, chocolate, ice cream, Grapes, Popcorn, canned salmon, pomegranate.
  • Regular exercise like walking, jogging is helpful.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.

What if I have taken an overdose of Cadiquis 2.5 Tablet

Do not take more than the prescribed dose of Cadiquis 2.5 Tablet as it may cause overdose. The symptoms of overdose include unusual bleeding or bruising, red/black/tarry stools, red/brown/pink urine and coughing up or vomiting blood or material that looks like coffee grounds. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Cadiquis 2.5 Tablet should not be used in children. Blood tests are advised before and while taking Cadiquis 2.5 Tablet to monitor kidney and liver functioning. If you are pregnant or breastfeeding, please inform your doctor before taking Cadiquis 2.5 Tablet . If you have a stomach ulcer, recent bleeding in the brain, kidney or liver problems, high blood pressure or bleeding problems, antiphospholipid syndrome (an immune system disorder that causes an increased risk of blood clots), inform your doctor before taking Cadiquis 2.5 Tablet .

Drug-Drug Interactions

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ApixabanDefibrotide
Critical

Drug-Drug Interactions

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ApixabanDefibrotide
Critical
How does the drug interact with Cadiquis 2.5 Tablet:
Coadministration of Defibrotide and Cadiquis 2.5 Tablet co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Defibrotide and Cadiquis 2.5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Cadiquis 2.5 Tablet:
Mifepristone and Cadiquis 2.5 Tablet co-administration have been associated with more severe vaginal bleeding in women.

How to manage the interaction:
Taking Cadiquis 2.5 Tablet with Mifepristone together is not generally recommended as it may lead to an interaction, but it can be taken if prescribed by a doctor. However, if you experience persistent, excessive bleeding, consult the doctor. Without consulting a doctor, never stop taking any medication.
ApixabanConivaptan
Severe
How does the drug interact with Cadiquis 2.5 Tablet:
Conivaptan may significantly increase the blood levels of Cadiquis 2.5 Tablet. This can increase the risk of serious bleeding complications.

How to manage the interaction:
Even though combining Conivaptan and Cadiquis 2.5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Cadiquis 2.5 Tablet:
Coadministration of Cadiquis 2.5 Tablet with Bromfenac may increase the risk or severity of bleeding which can lead to severe blood loss.

How to manage the interaction:
Although there is a possible interaction between Cadiquis 2.5 Tablet with Bromfenac, it can be taken if prescribed by your doctor. However, if you notice any unusual bleeding or bruising, or other signs and symptoms of bleeding, such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, you should seek immediate medical attention. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Cadiquis 2.5 Tablet:
Using ramucirumab together with Cadiquis 2.5 Tablet may increase the risk of bleeding.

How to manage the interaction:
Even though combining Ramucirumab and Cadiquis 2.5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Cadiquis 2.5 Tablet:
Coadministration of Regorafenib and Cadiquis 2.5 Tablet co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Regorafenib and Cadiquis 2.5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Cadiquis 2.5 Tablet:
Cadiquis 2.5 Tablet's blood levels can be considerably lowered by taking it along with Phenytoin leading to reduced effectiveness in treating your condition.

How to manage the interaction:
Although Co-administration of Phenytoin and Cadiquis 2.5 Tablet can lead to an interaction, they can be taken in case a doctor advises it to. Phenytoin makes Cadiquis 2.5 Tablet less effective in treating and preventing blood clots. Never discontinue taking a medication without consulting a doctor.
ApixabanFenoprofen
Severe
How does the drug interact with Cadiquis 2.5 Tablet:
Coadministration of Fenoprofen and Cadiquis 2.5 Tablet co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Fenoprofen and Cadiquis 2.5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
ApixabanOmacetaxine mepesuccinate
Severe
How does the drug interact with Cadiquis 2.5 Tablet:
Coadministration of Omacetaxine mepesuccinate and Cadiquis 2.5 Tablet co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Omacetaxine mepesuccinate and Cadiquis 2.5 Tablet may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Cadiquis 2.5 Tablet:
Coadministration of Heparin and Cadiquis 2.5 Tablet co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Heparin and Cadiquis 2.5 Tablet may cause an interaction, it is still possible to take it if a doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid vitamin K rich foods such as coriander, cabbage, spinach, broccoli, collard greens, kale (leaf cabbage), black liquorice, turnip greens, avocados, Brussels sprouts as they may decrease the effectiveness of Cadiquis 2.5 Tablet .

  • Do regular exercise as it helps to dissolve blood clots especially in obese people.

  • Do not consume more than 14 units of alcohol per week as excess alcohol intake may increase the risk of bleeding and quit smoking.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC
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Alcohol

Caution

You are recommended not to consume more than 14 units per week as exceeding this may increase the risk of bleeding.

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Pregnancy

Caution

Cadiquis 2.5 Tablet is a Category B pregnancy drug and is given to pregnant women only if doctor thinks benefits outweigh risks.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Cadiquis 2.5 Tablet as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Safe if prescribed

Cadiquis 2.5 Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Cadiquis 2.5 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Cadiquis 2.5 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Cadiquis 2.5 Tablet is not recommended for children below 18 years of age.

Have a query?

FAQs

Cadiquis 2.5 Tablet is used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung). Additionally, it is used to prevent blood clots in patients with atrial fibrillation (irregular heartbeat). Cadiquis 2.5 Tablet works by inhibiting the action of blood clotting factor (X a), which is an important element of blood clotting.

No, you are not recommended to take ibuprofen with Cadiquis 2.5 Tablet as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, red or black tarry stools, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.

No, you are usually not advised to have a tattoo or body piercing while taking Cadiquis 2.5 Tablet as it may increase the risk of bleeding and infection. If you still wish to proceed further, contact your doctor so that the dose may be adjusted or any antibiotics may be prescribed and let the piercer or tattooist know in advance that you are on treatment with a blood thinner.

Yes, you are advised to stop taking Cadiquis 2.5 Tablet a few days before surgery or procedure as Cadiquis 2.5 Tablet may increase the risk of bleeding. Therefore, before having any procedure or any surgery, please inform your doctor that you are taking Cadiquis 2.5 Tablet .

Yes, Cadiquis 2.5 Tablet helps in reducing the risk of stroke and heart attack by preventing blood clots. Stroke is caused as blood clots break off and travel to brain.

No, you are not recommended to stop taking Cadiquis 2.5 Tablet without consulting your doctor as it may worsen the condition. Therefore, take Cadiquis 2.5 Tablet for as long as your doctor has prescribed it.

If you have difficulty swallowing the tablet whole, please consult your doctor about alternative methods for taking Cadiquis 2.5 Tablet . The tablet can be crushed and mixed with water, 5% glucose in water, apple juice, or apple puree just before consumption.

If you miss a dose of Cadiquis 2.5 Tablet , take it as soon as you remember. Take the next dose of Cadiquis 2.5 Tablet at the usual time and then continue as normal.

Side effects of Cadiquis 2.5 Tablet include nausea, anaemia (lack of blood), and unusual bleeding, including swelling and bruising. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you have atrial fibrillation (a condition in which the heart beats irregularly) and are taking Cadiquis 2.5 Tablet to help prevent strokes or serious blood clots, in that case, you may be at a higher risk of having a stroke if you stop taking this medication. Besides this, you may be at risk of having a blood clot form in or around your spine that could cause paralysis if you have epidural or spinal anaesthesia or a spinal puncture while taking a blood thinner such as Cadiquis 2.5 Tablet .

Yes, Cadiquis 2.5 Tablet is a blood thinner. It belongs to the class of medicines known as factor Xa inhibitors which help prevent the formation of blood clots.

Symptoms of Cadiquis 2.5 Tablet overdose are unusual bleeding or bruising; red, brown, or pink urine; red or black, tarry stools; and coughing up or vomiting blood or material that looks like coffee grounds. Consult the doctor if you experience these symptoms or if you have taken an overdose.

Country of origin

India

Manufacturer/Marketer address

162, Bank Colony, Mandoli,Nand Nagari DELHI North West DL 110093 IN
Other Info - CAD0370

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