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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Calrcin 250mg Tablet is used to treat a wide range of bacterial infections, including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection, the affected skin appears swollen and red and is typically painful and warm to the touch), and ear infections. Besides this, it is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. It contains Clarithromycin, which inhibits the growth of bacteria. It may cause some common side effects, such as nausea, diarrhoea, vomiting, loss of appetite, bloating, indigestion, headaches and difficulty sleeping. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Consume Type :

ORAL

Return Policy :

Not Returnable

About Calrcin 250mg Tablet

Calrcin 250mg Tablet is used to treat a wide range of bacterial infections, including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection, the affected skin appears swollen and red and is typically painful and warm to the touch), and ear infections. Besides this, Calrcin 250mg Tablet is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori.

Calrcin 250mg Tablet contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Calrcin 250mg Tablet helps prevent infections.

Calrcin 250mg Tablet should only be if your doctor has prescribed you. Calrcin 250mg Tablet should not be stopped even if you feel better as it is an antibiotic medication, and completing the full course is necessary; otherwise, the infection might re-appear in a more severe form. Like all medicines, Calrcin 250mg Tablet may cause some common side effects, including feeling sick (nausea), diarrhoea and being sick (vomiting), losing your appetite, bloating and indigestion, headaches and difficulty sleeping. These side effects are temporary and may get resolved after some time; however, if this side persists, let your doctor know about this if you notice any sudden wheeziness, tightness in the chest or throat, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body) STOP TAKING your medicine and go to a doctor immediately.

Do not take Calrcin 250mg Tablet if allergic to azithromycin, other macrolide antibiotics, or any components present in Calrcin 250mg Tablet. Calrcin 250mg Tablet isn't normally recommended during pregnancy and while breastfeeding. But your doctor may prescribe it if the benefits of taking it are greater than the risks. Do not consume alcohol as it may cause excessive drowsiness when taken along with Calrcin 250mg Tablet. Before using the Calrcin 250mg Tablet, tell your doctor if you ever had an allergy to Calrcin 250mg Tablet have kidney problems, liver problems, swollen food pipe (oesophagitis), lupus disease (an autoimmune disease), or muscle disease (myasthenia gravis). Do not drink alcohol with Calrcin 250mg Tablet as it may increase the unpleasant side effects like drowsiness and dizziness.

Uses of Calrcin 250mg Tablet

Calrcin 250mg Tablet is used in the treatment of Bacterial infections. The detailed uses of Calrcin 250mg Tablet are as follows:
• Treatment of Respiratory Infections: Calrcin 250mg Tablet is commonly prescribed to treat respiratory infections such as bronchitis and pneumonia caused by susceptible bacteria.
• Skin Infections: Calrcin 250mg Tablet effectively treats skin infections like cellulitis or impetigo, caused by bacterial pathogens.
• Sinusitis: Calrcin 250mg Tablet is used to manage acute bacterial sinusitis, relieving symptoms like nasal congestion and facial pain caused by bacterial infections.
• Otitis Media: Calrcin 250mg Tablet is frequently utilized to treat middle ear infections (otitis media), providing relief from ear pain and inflammation.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it. Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.

Medicinal Benefits

Calrcin 250mg Tablet is a type of macrolide class of antibiotic which is effective against a wide range of bacteria, including gram-negative and gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections, including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori). Calrcin 250mg Tablet is sometimes used by people who have an allergy to penicillin and antibiotics similar to penicillin, such as amoxicillin.

How Calrcin 250mg Tablet Works

Calrcin 250mg Tablet contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Calrcin 250mg Tablet helps prevent infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Calrcin 250mg Tablet

  • Headache

  • Diarrhoea

  • Being sick (vomiting)

  • Nausea (feeling sick)

  • Loss of appetite

  • Taste change

  • Bloating

  • Indigestion

  • Abdominal pain

  • Insomnia (difficulty sleeping)

What if I have taken an overdose of Calrcin 250mg Tablet

Do not take more than the prescribed dose of Calrcin 250mg Tablet as it may cause overdose. The symptoms of overdose include diarrhoea, vomiting, nausea and stomach pain. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Calrcin 250mg Tablet in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Calrcin 250mg Tablet and iron supplements and antacids. Besides this, in some cases, the use of Calrcin 250mg Tablet causes antibiotic-associated diarrhoea. Calrcin 250mg Tablet may cause sensitive skin to sunlight and ultraviolet rays, causing an exaggerated sunburn reaction. Hence it is advisable to apply sunscreen before going outside. Its use has also been associated with an increased risk of fungal skin infections like (vaginal candidiasis - thrush). Tetracycline and Calrcin 250mg Tablet can form a stable calcium complex in bone-forming tissue, thereby affecting the growth of fibula bones in young children and bone development in the foetus. Using a Calrcin 250mg Tablet with isotretinoin should be avoided as it has been reported to cause pseudotumor cerebri (increased pressure inside the brain). Long-term use of Calrcin 250mg Tablet may affect your blood, kidney, and liver health, so yearly diagnostics test of these parameters is recommended.

Drug-Drug Interactions

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ClarithromycinRifabutin
Critical
ClarithromycinIsavuconazole
Critical

Drug-Drug Interactions

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ClarithromycinRifabutin
Critical
How does the drug interact with Calrcin 250mg Tablet:
Taking Rifabutin and Calrcin 250mg Tablet together may increase the blood levels of rifabutin.

How to manage the interaction:
Taking Rifabutin with Calrcin 250mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately If you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
ClarithromycinIsavuconazole
Critical
How does the drug interact with Calrcin 250mg Tablet:
When Isavuconazole is taken with Calrcin 250mg Tablet, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Calrcin 250mg Tablet and Isavuconazole can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinDronedarone
Critical
How does the drug interact with Calrcin 250mg Tablet:
When Dronedarone is taken with Calrcin 250mg Tablet, can increase the blood levels of dronedarone and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Calrcin 250mg Tablet with Dronedarone can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinAstemizole
Critical
How does the drug interact with Calrcin 250mg Tablet:
When Astemizole is taken with Calrcin 250mg Tablet, it can cause a decrease in the metabolism of Astemizole.

How to manage the interaction:
Taking Calrcin 250mg Tablet with Astemizole is not recommended, please consult your doctor before taking it.
ClarithromycinTolvaptan
Critical
How does the drug interact with Calrcin 250mg Tablet:
When Tolvaptan and Calrcin 250mg Tablet are taken together, may significantly increase the blood levels and effects of Tolvaptan.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Calrcin 250mg Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClarithromycinConivaptan
Critical
How does the drug interact with Calrcin 250mg Tablet:
When Calrcin 250mg Tablet is taken with Conivaptan, it can lower the rate at which Conivaptan is broken down in the body.

How to manage the interaction:
Taking Calrcin 250mg Tablet with Convivaptan can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, or seizures, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinNimodipine
Critical
How does the drug interact with Calrcin 250mg Tablet:
When Nimodipine is taken with Calrcin 250mg Tablet, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Calrcin 250mg Tablet and Nimodipine is not recommended as it can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heart rhythm, swelling, and low blood pressure, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinColchicine
Critical
How does the drug interact with Calrcin 250mg Tablet:
Coadministration of colchicine with Calrcin 250mg Tablet may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Taking Colchicine with Calrcin 250mg Tablet is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
ClarithromycinRanolazine
Critical
How does the drug interact with Calrcin 250mg Tablet:
When Ranolazine and Calrcin 250mg Tablet are taken together, significantly increases the blood levels and effects of Ranolazine.

How to manage the interaction:
Co-administration of Calrcin 250mg Tablet and Ranozaline can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
ClarithromycinSparfloxacin
Critical
How does the drug interact with Calrcin 250mg Tablet:
Co-administration of Calrcin 250mg Tablet and Sparfloxacin may result in an increased risk of QT interval prolongation.

How to manage the interaction:
Co-administration of Sertraline and Desvenlafaxine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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CLARITHROMYCIN-250MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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CLARITHROMYCIN-250MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice may delay the gastrointestinal absorption of Calrcin 250mg Tablet. Avoid grapefruit juice while on treatment with Calrcin 250mg Tablet.

Diet & Lifestyle Advise

  • Probiotics and prebiotics can also help to reduce the side effects of antibiotics.

  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. 

  • Eating grapefruit during antibiotics treatment can prevent the body from utilizing Calrcin 250mg Tablet properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic. 

  • Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of Calrcin 250mg Tablet. 

  • Avoid intake of alcoholic beverages with Calrcin 250mg Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Calrcin 250mg Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Calrcin 250mg Tablet Substitute

Substitutes safety advice
  • Claribid 250 Tablet 10's

    by Others

    24.08per tablet
  • Clarinova-250 Tablet 10's

    by Others

    18.63per tablet
  • Cloff 250 Tablet 10's

    by AYUR

    24.21per tablet
  • Claribid 250 DS Combipack Fruit Punch Suspension 30 ml

    by AYUR

    7.49per tablet
  • Clarigard 250 Tablet 10's

    by AYUR

    18.77per tablet
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Alcohol

Unsafe

Calrcin 250mg Tablet should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol.

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Pregnancy

Caution

Calrcin 250mg Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before taking Calrcin 250mg Tablet; your doctor will decide whether Calrcin 250mg Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Not enough scientific data available for Calrcin 250mg Tablet, hence it is advised to consult your doctor.

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Liver

Caution

Calrcin 250mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Calrcin 250mg Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Calrcin 250mg Tablet can be given safely to children in the form of suspension only, dose to be adjusted and recommended by a child specialist only.

FAQs

Calrcin 250mg Tablet is used to treat bacterial infections, including chest infections, skin infections, and ear infections. Besides this, Calrcin 250mg Tablet is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori.

Calrcin 250mg Tablet contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Calrcin 250mg Tablet helps in the prevention of infections.

You should avoid taking iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking Calrcin 250mg Tablet. Avoid taking any other antibiotics containing Calrcin 250mg Tablet unless your doctor has prescribed you.

After taking antibiotics such as Calrcin 250mg Tablet, some people get thrush, a fungal infection. This is due to the fact that antibiotics kill the regular, harmless bacteria that serve to protect you from thrush.

Calrcin 250mg Tablet treats only bacterial infections. It will not work for viral infections (such as common cold, flu).

No, Calrcin 250mg Tablet is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with doctor advice only.

Side-effects are rare with Calrcin 250mg Tablet and do not usually last long. They will get better after a day or two. if those side effects persist reach out to the doctor immediately.​

No, Calrcin 250mg Tablet should not be stopped even if you feel better as it is an antibiotic medication and completing the full course if very necessary; otherwise, the infection might re-appear in a more severe form.

Country of origin

India
Other Info - CA50777

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