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Cancrinase 3750 IU Injection is used to treat acute lymphoblastic leukaemia (ALL). It is also used with other chemotherapy drugs to treat a specific type of ALL in people who have had allergic reactions to medications similar to Pegaspargase, such as asparaginase. It contains Pegaspargase, an enzyme that breaks down asparagine, an essential building block of proteins without which cells cannot survive. It lowers the asparagine levels in blood cancer cells and stops them from growing.
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About Cancrinase 3750 IU Injection
Cancrinase 3750 IU Injection is used in the treatment of acute lymphoblastic leukaemia (ALL). It is also used with other chemotherapy drugs to treat a certain type of ALL in people who have had allergic reactions to medications similar to pegaspargase, such as asparaginase.
Cancrinase 3750 IU Injection contains Pegaspargase, an enzyme that breaks down asparagine, an important building block of proteins without which cells cannot survive. Cancrinase 3750 IU Injection lowers the asparagine levels in blood cancer cells and stops the cancer cells from growing.
In some cases, Cancrinase 3750 IU Injection may cause side effects such as tiredness, dizziness, fever, nausea, vomiting, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with the doctor if any of the side effects persist or worsen.
Do not receive Cancrinase 3750 IU Injection if you are pregnant or breastfeeding. Avoid driving or using machines as Cancrinase 3750 IU Injection may cause drowsiness, tiredness, and confusion. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.
Uses of Cancrinase 3750 IU Injection
Directions for Use
Medicinal Benefits
Cancrinase 3750 IU Injection is used to treat acute lymphoblastic leukaemia (ALL). It is also used with other chemotherapy drugs to treat a certain type of ALL in people who have had allergic reactions to medications similar to pegaspargase, such as asparaginase. Cancrinase 3750 IU Injection contains Pegaspargase, an enzyme that breaks down asparagine, an important building block of proteins without which cells cannot survive. Normal cells can make asparagine for themselves, while some cancer cells cannot. Cancrinase 3750 IU Injection lowers asparagine levels in blood cancer cells and stops the cancer cells from growing.
How Cancrinase 3750 IU Injection Works
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What if I have taken an overdose of Cancrinase 3750 IU Injection
Drug Warnings
Do not use Cancrinase 3750 IU Injection if you are allergic to any of its components if you have severe liver disease, pancreatitis (inflammation of the pancreas) or if you have ever had severe bleeding or blood clots following asparaginase therapy. Inform the doctor if you have had serious allergic reactions to other forms of asparaginase, if you suffer from a bleeding disorder or have had serious blood clots, if you get a fever if you have poor liver function, diabetes, stroke or abdominal pain. Seek medical attention if you experience symptoms of osteonecrosis (pain in the knee, back or hip), liver or pancreas problems (loss of appetite, upper stomach pain, nausea or vomiting, fast heart rate, dark urine, or yellowing of the skin or eyes), low blood cell count (fever, mouth sores, skin sores, sore throat, cough, trouble breathing), blood clot (sudden numbness or weakness, problems with vision or speech, swelling or redness in an arm or leg), high blood sugar (increased thirst, increased urination, dry mouth, fruity breath odour) or if you notice unusual bleeding, easy bruising, or purple/red spot under the skin.
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Alcohol
Caution
Please consult your doctor before consuming alcohol while on treatment with Cancrinase 3750 IU Injection as it may increase the risk of side effects such as liver damage.
Pregnancy
Caution
Pegaspargase belongs to pregnancy category C. The effects of Cancrinase 3750 IU Injection during pregnancy have not been studied. If you are pregnant, planning for pregnancy or think you may be pregnant, talk to the doctor for advice.
Breast Feeding
Unsafe
It is not known if Pegaspargase passes into breast milk. As a precautionary measure, breastfeeding should be discontinued during treatment and should not be re-started until after treatment with Cancrinase 3750 IU Injection has been discontinued.
Driving
Caution
Do not drive or operate machinery as Cancrinase 3750 IU Injection may cause tiredness, confusion, and drowsiness.
Liver
Caution
Cancrinase 3750 IU Injection is not recommended if you have severe liver disease. If you have a history of liver disease, inform your doctor before receiving Cancrinase 3750 IU Injection.
Kidney
Consult your doctor
If you have a history of kidney disease, inform your doctor before receiving Cancrinase 3750 IU Injection.
Children
Safe if prescribed
Cancrinase 3750 IU Injection is safe for use in children if prescribed by the doctor.
Have a query?
Cancrinase 3750 IU Injection is used to treat Acute lymphoblastic leukaemia (ALL).
Cancrinase 3750 IU Injection works by killing or stopping the growth of cancer cells.
If anticoagulants are used at the same time as Cancrinase 3750 IU Injection, there may be a higher risk of bleeding disorders. Therefore, consult the doctor if you are taking anticoagulant/blood thinner medicines.
Oral contraceptive is not an effective method of contraception whilst on treatment with Cancrinase 3750 IU Injection. Ask your doctor about the best contraceptive to use.
Cancrinase 3750 IU Injection may cause osteonecrosis (bone damage), especially when taken concomitantly with glucocorticoids. If you experience any new bone pain, like pain in the hip, back or knee, inform the doctor as soon as possible.
Consult the doctor if you are undergoing immunisation with live vaccines within 3 months of completing the treatment, as it may increase the risk of severe infections.
Cancrinase 3750 IU Injection can lead to fluctuations in clotting factors and may increase the risk of bleeding and/or clotting. If you notice unusual bleeding or bruising, consult the doctor.
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