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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Ceastra-XL 200 Capsule is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It contains Itraconazole, which works by killing fungi. Some people may experience side effects such as nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ITRACONAZOLE-200MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ceastra-XL 200 Capsule

Ceastra-XL 200 Capsule is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Ceastra-XL 200 Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.Thus, it causes the main components of fungal cells to leak out, killing fungi and clearing the fungal infection.

Take Ceastra-XL 200 Capsule as prescribed. Your doctor will advise you on how often you take Ceastra-XL 200 Capsule based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of Ceastra-XL 200 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Ceastra-XL 200 Capsule or any other medicines, please tell your doctor. Ceastra-XL 200 Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using Ceastra-XL 200 Capsule. Do not take Ceastra-XL 200 Capsule if you have or have heart failure, as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Ceastra-XL 200 Capsule. Avoid taking fentanyl (a strong opioid narcotic medicine) with Ceastra-XL 200 Capsule as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking Ceastra-XL 200 Capsule and consult your doctor immediately as they might be symptoms of nerve damage.

Uses of Ceastra-XL 200 Capsule

Ceastra-XL 200 Capsule is used in the treatment of fungal infections. The detailed uses of Ceastra-XL 200 Capsule are as follows:
• Yeast Infection Treatment: Ceastra-XL 200 Capsule is commonly used to combat vaginal yeast infections caused by the Candida fungus.
• Fungal Infection Management: Ceastra-XL 200 Capsule effectively treats various systemic fungal infections, especially in individuals with weakened immune systems.
• Preventive Care: Doctors may prescribe Ceastra-XL 200 Capsule to prevent fungal infections in patients undergoing chemotherapy or those prone to such infections due to immune deficiencies.
• Oral Thrush Treatment: Ceastra-XL 200 Capsule is also useful in managing oral candidiasis (thrush), a fungal overgrowth in the mouth caused by Candida.

Directions for Use

Tablet: Take it with food to avoid stomach upset or as advised by the doctor. Swallow the whole tablet with a glass of water. Do not break, crush or chew it. If you are taking any stomach acid suppressor or have achlorhydria (stomach does not produce hydrochloric acid), take Ceastra-XL 200 Capsule with cola.

Medicinal Benefits

Ceastra-XL 200 Capsule is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Ceastra-XL 200 Capsule inhibits the production of ergosterol (a main component of the cell membranes of fungi). This weakens and damages the fungal cell membranes, causing the main components of fungal cells to leak out. Thus, it kills fungi and clears the fungal infection.

How Ceastra-XL 200 Capsule Works

Ceastra-XL 200 Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of the cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.Thus, it causes the main components of fungal cells to leak out, killing fungi and clearing the fungal infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Ceastra-XL 200 Capsule
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • To help reduce symptoms, eat foods high in vitamin C, such as oranges, bell peppers and strawberries.
  • Lightly blow your nose to remove mucus; steer clear of blowing hard.
  • Infections can be prevented from spreading by washing hands frequently and staying away from other people.
  • If you have allergies, do your best to avoid triggering allergens that could contribute to a runny nose.
  • Don't smoke, as irritating the nasal passages can make a runny nose worse.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
Here's a comprehensive approach to managing medication-triggered high blood pressure (hypertension):
  • Inform your doctor if you experience high blood pressure symptoms after starting a new medication or changing your medication regimen.
  • To reduce high blood pressure symptoms, your doctor may change your medication regimen or dose.
  • Monitor your blood pressure regularly to track changes and potential side effects.
  • Make lifestyle changes, such as following a healthy diet, exercising regularly, and reducing sodium intake.
  • Consider incorporating stress-reducing activities, like meditation or deep breathing exercises, into your daily routine.
  • Create a personalized plan with your doctor to manage high blood pressure, which may include additional medications, therapies, or lifestyle modifications.
  • Follow up with your doctor on a frequent basis to assess progress, change treatment plans, and address any concerns or issues.

What if I have taken an overdose of Ceastra-XL 200 Capsule

Do not take more than the prescribed dose of Ceastra-XL 200 Capsule as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

If you are known to be allergic to Ceastra-XL 200 Capsule or any other medicines, please tell your doctor. Ceastra-XL 200 Capsule is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Ceastra-XL 200 Capsule. Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with Ceastra-XL 200 Capsule, as it may cause severe breathing problems and can even lead to death. Do not take Ceastra-XL 200 Capsule if you have had heart failure, as it may cause severe, life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking Ceastra-XL 200 Capsule and consult a doctor immediately, as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking Ceastra-XL 200 Capsule.

Drug-Drug Interactions

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ItraconazoleSimvastatin
Critical
ItraconazoleTriazolam
Critical

Drug-Drug Interactions

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ItraconazoleSimvastatin
Critical
How does the drug interact with Ceastra-XL 200 Capsule:
Simvastatin's blood levels and effects may be greatly increased when combined with Ceastra-XL 200 Capsule.

How to manage the interaction:
Simvastatin and Ceastra-XL 200 Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you have side effects such unexplained pain in the muscles or tenderness, muscle weakness, fever or flu-like symptoms, or dark urine. Without consulting a doctor, never stop taking any medication.
ItraconazoleTriazolam
Critical
How does the drug interact with Ceastra-XL 200 Capsule:
Co-administration of Triazolam and Ceastra-XL 200 Capsule may significantly increase the levels of Triazolam.

How to manage the interaction:
Although combining Triazolam and Ceastra-XL 200 Capsule may possibly lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
ItraconazoleFelodipine
Critical
How does the drug interact with Ceastra-XL 200 Capsule:
The blood levels and effects of felodipine may be considerably increased by taking Ceastra-XL 200 Capsule together with felodipine.

How to manage the interaction:
Although there is a possible interaction between felodipine and Ceastra-XL 200 Capsule, they can be taken if prescribed by a doctor. Consult a physician if you have an irregular heartbeat, Edema (accumulation of fluid in hands or legs), or abnormally low blood pressure. Without first consulting a doctor, never stop taking medicines.
ItraconazoleAvanafil
Critical
How does the drug interact with Ceastra-XL 200 Capsule:
Co-administartion of avanafil and Ceastra-XL 200 Capsule may considerably raise the blood levels of Avanafil.

How to manage the interaction:
Although combining avanafil and Ceastra-XL 200 Capsule may possibly lead to an interaction, they can be taken if prescribed by a doctor. Consult a physician if you develop any side effects, including priapism (prolonged and painful erection unrelated to sexual activity), low blood pressure, fainting, visual problems, including loss of vision, ringing in the ears, hearing loss, and low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleNisoldipine
Critical
How does the drug interact with Ceastra-XL 200 Capsule:
The blood levels and effects of nisoldipine may be greatly increased when used with Ceastra-XL 200 Capsule.

How to manage the interaction:
Nisoldipine and Ceastra-XL 200 Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a physician if you have symptoms that include an irregular heartbeat, accumulation of fluid in legs or hands, or abnormally low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleAlprazolam
Critical
How does the drug interact with Ceastra-XL 200 Capsule:
Alprazolam's blood levels may be significantly raised when combined with Ceastra-XL 200 Capsule.

How to manage the interaction:
Although combining Alprazolam and Ceastra-XL 200 Capsule may lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
ItraconazoleTicagrelor
Critical
How does the drug interact with Ceastra-XL 200 Capsule:
The blood levels and effects of ticagrelor may be greatly increased when combined with Ceastra-XL 200 Capsule.

How to manage the interaction:
Ceastra-XL 200 Capsule and ticagrelor may interact, however if prescribed by a physician, they can be used together. While receiving therapy, you should consult a doctor if you develop any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Without consulting a doctor, never stop taking any medication.
ItraconazoleIsavuconazole
Critical
How does the drug interact with Ceastra-XL 200 Capsule:
The blood levels and effects of Isavuconazole may be significantly enhanced by taking Ceastra-XL 200 Capsule along with it.

How to manage the interaction:
Co-administration of Isavuconazole and Ceastra-XL 200 Capsule can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ItraconazoleTolvaptan
Critical
How does the drug interact with Ceastra-XL 200 Capsule:
Co-administration of Tolvaptan and Ceastra-XL 200 Capsule may significantly raise Tolvaptan blood levels and effects.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Ceastra-XL 200 Capsule, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
ItraconazoleSolifenacin
Critical
How does the drug interact with Ceastra-XL 200 Capsule:
The blood levels and effects of solifenacin may be greatly increased when combined with Ceastra-XL 200 Capsule.

How to manage the interaction:
Solifenacin and Ceastra-XL 200 Capsule may interact, however, if recommended by a physician, they are safe to consume. Consult a doctor if you feel sleepy, or uneasy, have an irregular heartbeat, have blurry vision, have trouble urinating, have a dry mouth, a headache, have digestive problems, or have constipation. Without consulting a doctor, never stop taking any medication.

Drug-Food Interactions

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ITRACONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ITRACONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit, Grapefruit juice with Ceastra-XL 200 Capsule may impair the absorption of Ceastra-XL 200 Capsule, resulting in decreased antifungal effects. Avoid consuming Grapefruit and grapefruit juice with Ceastra-XL 200 Capsule.

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • Don't walk barefoot in wet places such as changing rooms and gym showers to prevent fungal infections.
  • Do not scratch the affected area of skin, as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Ceastra-XL 200 Capsule Substitute

Substitutes safety advice
  • Itracip 200 mg Capsule 10's

    by Others

    24.75per tablet
  • Candiforce-200 Capsule 10's

    by Others

    22.28per tablet
  • Canditral 200 Capsule 10's

    by Others

    22.28per tablet
  • Syntran 200 Capsule 10's

    by Others

    22.28per tablet
  • Itralase 200 Capsules 10's

    by AYUR

    22.28per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with Ceastra-XL 200 Capsule as it may increase the risk of liver problems and other adverse effects.

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Pregnancy

Unsafe

Ceastra-XL 200 Capsule is category C pregnancy drug and is unsafe for pregnant women as it may cause harm to the unborn baby. Therefore, inform your doctor if you are pregnant or planning for pregnancy before taking Ceastra-XL 200 Capsule.

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Breast Feeding

Caution

Ceastra-XL 200 Capsule is excreted in human milk and may harm the baby. Therefore, Ceastra-XL 200 Capsule is given to breastfeeding mothers only if doctor thinks benefits are greater than risks.

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Driving

Caution

Ceastra-XL 200 Capsule may cause dizziness, hearing loss, double or blurred vision in some people. Therefore, drive only if you alert after taking Ceastra-XL 200 Capsule.

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Liver

Caution

Take Ceastra-XL 200 Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Ceastra-XL 200 Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Ceastra-XL 200 Capsule is not recommended for children below 12 years as the safety and effectiveness were not established.

FAQs

Ceastra-XL 200 Capsule is used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby killing fungi and clearing the fungal infection.

You are not recommended to take Ceastra-XL 200 Capsule with simvastatin as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark coloured urine, fever or flu symptoms. However, please consult a doctor before using Ceastra-XL 200 Capsule with other medicines.

No, Ceastra-XL 200 Capsule is not recommended for use during pregnancy as it may cause harm to the fetus. Also, it is advised to use effective contraceptive measures while taking Ceastra-XL 200 Capsule and after 2 months of stopping treatment with Ceastra-XL 200 Capsule. However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Ceastra-XL 200 Capsule.

Ceastra-XL 200 Capsule may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Ceastra-XL 200 Capsule to experience this adverse effect. However, if you notice any changes in hearing, stop taking Ceastra-XL 200 Capsule and consult a doctor immediately.

You are advised to take antacids (drugs used to reduce acid in the stomach) such as omeprazole, pantoprazole and esomeprazole at least 1 hour before or 2 hours after taking Ceastra-XL 200 Capsule as co-administration of these medicines at the same time may reduce the effectiveness of Ceastra-XL 200 Capsule because antacids decrease the absorption and blood levels of Ceastra-XL 200 Capsule. However, please consult a doctor before taking other medicines with Ceastra-XL 200 Capsule.

Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.

You are not recommended to stop taking Ceastra-XL 200 Capsule without consulting your doctor as it may cause recurring infection. Therefore, take Ceastra-XL 200 Capsule for as long as your doctor has prescribed it, and if you experience any difficulty while taking Ceastra-XL 200 Capsule, please consult your doctor.

Inform your doctor if you are sexually active and discuss effective contraception methods. Ceastra-XL 200 Capsule may reduce the effectiveness of oral contraceptive pills. Thus, you are advised to use barrier methods of contraception like condoms, if you are taking Ceastra-XL 200 Capsule.

Inform the doctor about your detailed medical and surgical history, if you have liver, kidney or heart disease or fits and if you are pregnant, breastfeeding or planning pregnancy. Inform your doctor if you are taking any other medicines including supplements or herbal products as Ceastra-XL 200 Capsule may interact with other medicines. Also, let your doctor know if you are stopping any medicine.

Ceastra-XL 200 Capsule contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.

Yes, you should swallow the capsule whole with a glass of water. Do not crush, chew or break it.

The side effects of Ceastra-XL 200 Capsule include nausea, headache, diarrhoea, stomach pain, fatigue (overtiredness), back pain, cough, and sore throat. If these side effects persist or worsen, please consult your doctor.

If you have taken overdose of Ceastra-XL 200 Capsule, please consult your doctor immediately.

Store Ceastra-XL 200 Capsule at room temperature. Protect from light and moisture. Keep out of reach and sight of children.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - CEA0012

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