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  3. Cefrine Syrup 30 ml

Cefrine Syrup 30 ml, Pack of 1 Syrup
Cefrine Syrup 30 ml, Pack of 1 Syrup
Cefrine Syrup 30 ml, Pack of 1 Syrup
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Written By Bayyarapu Mahesh Kumar , M Pharmacy

Cefrine Syrup is used to treat bacterial infections. It contains Cefdinir, which works by interfering with the formation of the bacterial cell wall and killing the bacteria. In some cases, this medicine may cause side effects such as diarrhoea, nausea, stomach pain, vomiting, rash, and headache. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

CEFDINIR-125MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Cefrine Syrup

Cefrine Syrup belongs to a class of medication called 'antibiotics' used to treat several bacterial infections of the urinary tract, bones and joints, heart, lungs, brain, chest, ears, skin or soft tissues. Bacterial infection is when harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Cefrine Syrup does not work against infections caused by a virus such as flu or a common cold.

Cefrine Syrup contains Cefdinir, a cephalosporin antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. This damages the bacterial cell wall and kills bacteria.

Take Cefrine Syrup as prescribed by your doctor. You are advised to take Cefrine Syrup for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhoea, nausea, stomach pain, vomiting, rash, headache or vaginal itching or discharge. Most of these side effects of Cefrine Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Cefrine Syrup, cephalosporin antibiotics or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor before taking Cefrine Syrup. Cefrine Syrup is not recommended for babies below six months of age as the safety and effectiveness were not established. Drive only if alert, as the Cefrine Syrup may cause dizziness. You are advised to maintain a time gap of a minimum of 2 hours between taking Cefrine Syrup and antacids containing aluminium, magnesium, iron supplements and multivitamins containing iron. These may reduce the body's absorption of Cefrine Syrup by the body.

Uses of Cefrine Syrup

Cefrine Syrup is used to treat Bacterial infections.

Directions for Use

Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup, dosing syringe, or dropper.

Medicinal Benefits

Cefrine Syrup contains Cefdinir, a cephalosporin antibiotic used to treat several bacterial infections. Cefdinir is a broad-spectrum antibiotic that acts against aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. It interferes with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria.

How Cefrine Syrup Works

Cefrine Syrup contains Cefdinir, a cephalosporin antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. This damages the bacterial cell wall and kills bacteria.

Storage

Store in a cool and dry place away from sunlight
Side effects of Cefrine Syrup 30 ml
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Your doctor may adjust the dose of your medication, discontinue, or switch to alternative medicines to manage your symptoms.
  • Drink plenty of water and caffeine-free drinks.
  • Eat more fibre by consuming fruits, vegetables, and whole grains.
  • Avoid processed, spicy, or fatty foods.
  • Try not to skip meals, delay eating, or eat too quickly.
  • Regular exercise can help improve digestion and promote better stool movement.
Managing Medication-Triggered Moniliasis (a yeast infection): A Step-by-Step Guide:
  • If you experience symptoms like itching, burning, redness, or discharge after taking medication, consult your doctor immediately and share your symptoms, medication regimen, and medical history.
  • Your doctor will assess your medication regimen to determine if it's contributing to the moniliasis and identify the best course of action to manage your condition.
  • Your doctor may prescribe antifungal medications or recommend other treatments to help clear up the infection. They may also suggest self-care measures to help manage symptoms and prevent future infections.
  • If your condition doesn't improve or persists, consult your doctor and report it. Your doctor will assess your progress, adjust your treatment plan, and provide advice to ensure the best outcome.

Drug Warnings

Please tell your doctor if you are allergic to Cefrine Syrup, cephalosporin antibiotics, or other medicines. If you have kidney problems or inflammation of the large intestine, inform your doctor before taking Cefrine Syrup. If you are pregnant or breastfeeding, consult a doctor before taking Cefrine Syrup. Cefrine Syrup is not recommended for babies below six months of age as the safety and effectiveness were not established. Drive only if alert, as the Cefrine Syrup may cause dizziness. You are recommended to complete the entire course of Cefrine Syrup as your doctor prescribes for effective results. Cefrine Syrup may interact with specific tests such as glucose (sugar) in urine and Coomb's test, giving false-positive results. Therefore, inform your doctor that you are taking Cefrine Syrup before undergoing any tests. You are advised to maintain a time gap of a minimum of 2 hours between taking Cefrine Syrup and antacids containing aluminium, magnesium, iron supplements and multivitamins containing iron. These may reduce the body's absorption of Cefrine Syrup by the body.

Drug-Drug Interactions

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CefdinirBCG vaccine
Critical
CefdinirLepirudin
Severe

Drug-Drug Interactions

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CefdinirBCG vaccine
Critical
How does the drug interact with Cefrine Syrup 30 ml:
Taking Cefrine Syrup 30 ml with BCG vaccine may reduce the effects of BCG vaccine.

How to manage the interaction:
Taking Cefrine Syrup 30 ml with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
CefdinirLepirudin
Severe
How does the drug interact with Cefrine Syrup 30 ml:
Taking Cefrine Syrup 30 ml with lepirudin may reduce the beneficial effects of therapy.

How to manage the interaction:
Although taking Cefrine Syrup 30 ml and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without first talking to your doctor.
CefdinirBivalirudin
Severe
How does the drug interact with Cefrine Syrup 30 ml:
Taking Cefrine Syrup 30 ml with bivalirudin may increase the effects of bivalirudin.

How to manage the interaction:
Although taking Cefrine Syrup 30 ml and Argatroban together can evidently cause an interaction, but it can be taken if prescribed by a doctor. In case you experience any side effects like chest tightness, shortness of breath, swelling of legs, or palpitations, consult a doctor. Do not stop using any medications without first talking to your doctor.
CefdinirHeparin
Severe
How does the drug interact with Cefrine Syrup 30 ml:
Taking Cefrine Syrup 30 ml with heparin may enhance the effects of heparin by anticoagulation(preventing blood from clotting).

How to manage the interaction:
Although taking Cefrine Syrup 30 ml and Heparin can cause an interaction, it can be taken if a doctor has suggested it. In case you experience aby unusual effects like lightheadedness, dizziness, unusual bruising, bleeding tendencies, blood in stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.
CefdinirDalteparin
Severe
How does the drug interact with Cefrine Syrup 30 ml:
Taking Cefrine Syrup 30 ml with dalteparin together may decrease the therapeutic effects of dalteparin.

How to manage the interaction:
Although taking Cefrine Syrup 30 ml and dalteparin can evidently cause an interaction, it can be taken if your doctor has suggested it. In case you experience aby unusual effects like lightheadedness, dizziness, unusual bruising, bleeding tendencies, blood in stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.
CefdinirFondaparinux
Severe
How does the drug interact with Cefrine Syrup 30 ml:
Taking fondaparinux and Cefrine Syrup 30 ml may increase the effects of fondaparinux.

How to manage the interaction:
Although taking Cefrine Syrup 30 ml and Fondaparinux can evidently cause an interaction, it can be taken if your doctor has suggested it. In case you experience aby unusual effects like lightheadedness, dizziness, unusual bruising, bleeding tendencies, blood in stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.
CefdinirArgatroban
Severe
How does the drug interact with Cefrine Syrup 30 ml:
Taking Cefrine Syrup 30 ml with argatroban may lead to increase in the effects of Argatroban.

How to manage the interaction:
Although taking Cefrine Syrup 30 ml and Argatroban together can evidently cause an interaction, but it can be taken if prescribed by a doctor. In case you experience any side effects like chest tightness, shortness of breath, swelling of legs, or palpitations, consult a doctor. Do not stop using any medications without first talking to your doctor.
CefdinirCholera, live attenuated
Severe
How does the drug interact with Cefrine Syrup 30 ml:
Taking Cefrine Syrup 30 ml with Cholera vaccine can reduce the activity of the Cholera vaccine.

How to manage the interaction:
Taking Cefrine Syrup 30 ml with Cholera, live attenuated together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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CEFDINIR-125MGVitamin B complex foods, Vitamin B12 rich foods
Moderate

Drug-Food Interactions

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CEFDINIR-125MGVitamin B complex foods, Vitamin B12 rich foods
Moderate
Common Foods to Avoid:
Avocado, Beetroot, Cereals, Cheese, Chicken, Black Beans, Eggs, Clams, Chickpea, Whole Grains, Shellfish, Spinach, Salmon, Red Meat, Oysters, Potatoes, Kidney Beans, Mackerel, Milk, Kale, Tuna, Yogurt, Liver, Low-Fat Milk, Trout, Fortified Breakfast Cereal, Fish, Beef

How to manage the interaction:
Cefrine Syrup 30 ml should not be taken orally with a multivitamin that contains minerals. Iron-containing products decreases the effects of Cefrine Syrup 30 ml. Although there is an interaction between Cefrine Syrup 30 ml and multivitamins, it can be taken if advised by a doctor. It should be taken two hours either before or after the dosage of the multivitamin with minerals.

Diet & Lifestyle Advise

  • Take probiotics after completing the entire course of Cefrine Syrup to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea.
  • Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut, and kimchi can help to restore the good bacteria of the intestine.
  • Include fibre-rich foods, which can be easily digested by your gut bacteria and help stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as brown rice and whole-grain bread should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking Cefrine Syrup.
  • Avoid alcohol consumption as it may increase adverse effects.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Cefrine Syrup Substitute

Substitutes safety advice

  • Adcef Suspension 30 ml

    by Others

    ₹6.66per tablet

  • Kefnir Suspension 30 ml

    by Others

    ₹2.99per tablet

  • Adcef DT Tablet 10's

    by Others

    ₹14.04per tablet

  • Aldinir Suspension 30 ml

    by Others

    ₹2.35per tablet

  • CEFDIEL 125MG SUSPENSION 30ML

    by Others

    ₹0.90per tablet

Product Substitutes

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Alcohol

Caution

The interaction of Cefrine Syrup with alcohol is unknown. Please consult a doctor before consuming alcohol while using Cefrine Syrup.

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Pregnancy

Caution

Cefrine Syrup is a category B pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

It is unknown whether Cefrine Syrup is excreted in human milk. Cefrine Syrup is given to breastfeeding mothers if the doctor thinks the benefits outweigh the risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Cefrine Syrup may cause dizziness in some people. Therefore, avoid driving if you feel dizzy after taking Cefrine Syrup.

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Liver

Safe if prescribed

If you have any concerns regarding the use of Cefrine Syrup in patients with liver problems, please consult a doctor.

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Kidney

Caution

Take Cefrine Syrup with caution, especially if you have a history of Kidney diseases or conditions. Your doctor may adjust the dose as needed.

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Children

Caution

Cefrine Syrup is not recommended for babies below 6 months of age as the safety and effectiveness were not established.

FAQs

Cefrine Syrup is used to treat bacterial infections of the urinary tract, bones and joints, heart, lungs, brain, chest, ears, skin or soft tissues.

Cefrine Syrup contains Cefdinir, an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering), which is necessary for their survival. This damages the bacterial cell wall and kills the bacteria.

It is not recommended to take Cefrine Syrup with probenecid (used to lower high uric acid levels) as it may increase the levels of Cefrine Syrup in the blood and increase the risk of adverse effects such as diarrhoea, kidney problems, vomiting, and nausea. However, please consult your doctor before taking Cefrine Syrup with other medicines.

Cefrine Syrup may cause diarrhoea, a common side effect. However, if the condition persists or worsens, or if you notice blood or mucus in your stools, avoid taking Cefrine Syrup and consult a doctor immediately.

Cefrine Syrup may interfere with the urine test (for sugar) and the Coombs test (for blood test), giving false-positive results. Therefore, if you are about to undergo any laboratory tests, inform your doctor or lab technician that you are taking Cefrine Syrup.

Cefrine Syrup is not used to treat viral infections; it is an antibiotic used only to treat bacterial infections.

You are advised to maintain a time gap of at least 2 hours between taking Cefrine Syrup and antacids containing aluminium and magnesium, as these may reduce the body's absorption of Cefrine Syrup. However, please consult a doctor before taking other medicines with Cefrine Syrup.

Country of origin

India

Manufacturer/Marketer address

409, Antriksh Bhawan, 22 Kasturba Gandhi Marg, New Delhi - 110 001.
Other Info - CEF0061

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/1999/50739S2LBL.PDF
  2. https://www.drugs.com/mtm/cefdinir.html
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