Celofos 1000 Injection 1 ml belongs to a group of medications called ‘anti-neoplastic'. It is used in the treatment of blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer (a type of cancer that begins in the ovaries), testicular cancer (cancer occurs in the testicles (testes), (which are located inside the scrotum, a loose bag of skin underneath the penis), and pancreatic cancer (a type of cancer that begins in the pancreas). Blood cancer begins in blood-forming tissue, such as the bone marrow or the immune system's cells. Examples of blood cancer are leukemia ( a blood cancer caused by a rise in the number of white blood cells in your body), lymphoma (cancer that begins in infection-fighting cells of the immune system, called lymphocytes), and multiple myeloma (cancer that forms in a type of white blood cell called a plasma cell).

Celofos 1000 Injection 1 ml contains ‘ifosfamide’, which is an anti-cancer drug. Celofos 1000 Injection 1 ml works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication. 

Celofos 1000 Injection 1 ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side effects such as nausea, vomiting, anemia (low number of red blood cells), hair loss, decreased white blood cell count, infection, blood in urine, CNS toxicity. Most of these side effects of Celofos 1000 Injection 1 ml do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Do not take Celofos 1000 Injection 1 ml if you are allergic to any other ingredients present in it. Do not self-administer Celofos 1000 Injection 1 ml. Before taking Celofos 1000 Injection 1 ml, talk to your doctor if you have a history of kidney disease, heart diseases, liver diseases, bone marrow suppression, cystitis, CNS toxicity. Celofos 1000 Injection 1 ml is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking Celofos 1000 Injection 1 ml. It is not recommended for use in children under 1 year of age. 

Celofos 1000 Injection 1 ml contains ‘ifosfamide’, which is an anti-cancer drug. It is used to treat blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer, and pancreatic cancer. Celofos 1000 Injection 1 ml works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication. 

• Nausea
• Vomiting
• Anemia (low number of red blood cells)
• Hair loss
• Decreased white blood cell count
• Infection
• Blood in urine
• CNS toxicity
• Dehydration
• Dry mouth/increased thirst
• Pale/wrinkled skin
• Temporary hair loss
• Trouble breathing

Do not take Celofos 1000 Injection 1 ml if you are allergic to any other ingredients present in it. Do not self-administer Celofos 1000 Injection 1 ml. Before taking Celofos 1000 Injection 1 ml, talk to your doctor if you have a history of kidney disease, heart diseases, liver diseases,  cystitis, CNS toxicity. Celofos 1000 Injection 1 ml is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking Celofos 1000 Injection 1 ml. It is not recommended for use in children under 1 year of age. Celofos 1000 Injection 1 ml should be used with caution in infections. Because the chances of infections are more in patients receiving this medicine. Hold the chemotherapy and start with broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary. Consumption of alcohol is not recommended while receiving this Celofos 1000 Injection 1 ml as it may increase the risk of adverse effects such as dizziness, drowsiness, abnormal muscle movements, seizures. Celofos 1000 Injection 1 ml may cause bone marrow suppression, which lowers the white blood cell count (neutrophils) and platelets. Close monitoring of blood cell count is necessary.

Drug-Drug Interactions: Celofos 1000 Injection 1 ml may interact with live attenuated vaccines,  TNF- blockers (etanercept, adalimumab), antifungal (fluconazole, itraconazole, ketoconazole); antiepileptic ( carbamazepine, phenytoin, phenobarbital), antihypertensive (diltiazem, enalapril), antibiotic (amphotericin-B, rifampin), antipsychotics (clozapine), anti-metabolites (cisplatin).

Drug-Food Interactions: Celofos 1000 Injection 1 ml may interact with grapefruit, st. John's wort and alcohol increase the risk of side effects.

Drug-Disease Interactions: Celofos 1000 Injection 1 ml should be used with caution in patients with heart diseases, liver diseases, kidney diseases, bone marrow suppression, CNS toxicity, cystitis, and infections.

• CISPLATIN
• AMPHOTERICIN B
• RIFAMPIN
• DILITAZEM
• ENALAPRIL
• CLOZAPINE
• CARBAMAZEPINE
• PHENYTOIN
• PHENOBARBITAL
• FLUCONAZOLE
• ITRACONAZOLE
• KETOCONAZOLE
• ETANERCEPT
• ADALIMUMAB

• Eat a variety of protein-rich foods that are low in fat. Include seafood, lean meat and poultry, greek yoghurts, eggs, beans, soy products, and unsalted nuts and seeds.
• Take vitamin A foods, found in green- or orange-coloured fruits and vegetables, such as sweet potatoes, carrots, kale, spinach, and apricots.
• Stay away from strong-smelling foods to avoid aggravating any disorders of taste.
• Avoid fatty fried, spicy, and overly sweet foods, as they may induce nausea.
• Avoid refined sugars (including raw, brown, and palm sugar) and refined carbohydrates, as most tumours prefer glucose as an energy source.
• Avoid drinking alcohol.
• Quit smoking.

• Regular monitoring of kidney, liver function, and levels of blood cells in your blood.
• Drink plenty of fluids while taking this Celofos 1000 Injection 1 ml to minimize damage to your bladder and kidneys.

Blood cancer:  Blood cancer begins in blood-forming tissue, such as the bone marrow or the immune system's cells. Examples of blood cancer are leukemia ( a blood cancer caused by a rise in the number of white blood cells in your body), lymphoma (cancer that begins in infection-fighting cells of the immune system, called lymphocytes), and multiple myeloma (cancer that forms in a type of white blood cell called a plasma cell). Symptoms include fever, chills., fatigue, weakness, bone and joint pain, weight loss.

Ovarian cancer:  Ovarian cancer is when abnormal cells in the ovary begin to multiply out of control and form a tumor. If left untreated, the tumor can spread to other parts of the body. This is called metastatic ovarian cancer. Symptoms include abdominal bloating, pressure, pain, abnormal fullness after eating, difficulty eating, increased urination, and an increased urge to urinate.

Breast cancer: Cancer that forms in the cells of the breasts. Breast cancer can occur in women and rarely in men. Symptoms of breast cancer include a lump in the breast, bloody discharge from the nipple, and changes in the shape or texture of the nipple or breast.

Testicular cancer: Testicular cancer occurs in the testicles (testes), located inside the scrotum, a loose bag of skin underneath the penis. Symptoms include a painless lump or swelling on either testicle, pain, discomfort, numbness in a testicle or the scrotum, change in the way a testicle feels, or a feeling of heaviness the scrotum, a dull ache in the lower abdomen or groin. Sudden buildup of fluid in the scrotum.

Pancreatic cancer: Pancreatic cancer is cancer that forms in the cells of the pancreas. Pancreatic cancer begins in your pancreas tissues — an organ in your abdomen that lies behind the lower part of your stomach. Your pancreas releases enzymes that aid digestion and produce hormones that help manage your blood sugar. Symptoms include abdominal pain that radiates to your back, loss of appetite or unintended weight loss, yellowing of your skin and the whites of your eyes (jaundice), light-colored stools, dark-colored urine, itchy skin.

Non-small cell lung cancer: Non-small cell lung cancer is a disease in which malignant (cancer) cells form in the lung tissues. There are several types of non-small cell lung cancer. Smoking is the major risk factor for non-small cell lung cancer. Symptoms include a cough that won't go away, shortness of breath, weight loss, or coughing up blood.