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Celofos 2000 Injection is used in the treatment of different kinds of cancer, such as blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer, and pancreatic cancer. Sometimes, you may experience specific side effects such as nausea, diarrhoea, vomiting, loss of appetite, headache, dizziness, hair loss, abdominal pain, pain or redness at the injection site, fever, sore throat, and cough. Before receiving this medicine, you should inform your doctor if you are allergic to any of its ingredients or if you are pregnant or breastfeeding, and about all the medications you are taking and any pre-existing medical conditions to rule out the potential side effects.

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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Celofos 2000 Injection

Celofos 2000 Injection is used to treat different cancers such as Blood, breast, non-small cell, ovarian, testicular, and pancreatic cancer. Cancer is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells. These cells can form tumours or spread to other body parts, interfering with normal function.

Celofos 2000 Injection is a combination medication. It contains ifosfamide (antineoplastic agent) and mesna (cytoprotectants). Celofos 2000 Injection works by damaging the genetic material (DNA and RNA) of cancer cells, stopping their growth and multiplication. 

Sometimes, you may experience specific side effects such as nausea, diarrhoea, vomiting, loss of appetite, headache, dizziness, hair loss, abdominal pain, pain or redness at the injection site, fever, sore throat, and cough. Most of these side effects will resolve gradually over time and do not require medical attention. However, consult the doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Celofos 2000 Injection may cause dizziness. Therefore, avoid driving or operating heavy machinery unless you are fully alert. Celofos 2000 Injection is safe for children if prescribed by the doctor. Celofos 2000 Injection should not be given to children as its safety and efficacy have not been established. Consumption of alcohol is not recommended while receiving this Celofos 2000 Injection as it may increase the risk of adverse effects such as dizziness, drowsiness, abnormal muscle movements, and seizures. Inform your doctor about your pre-existing medical conditions and if you are taking any other medications to prevent potential side effects.

Uses of Celofos 2000 Injection

Celofos 2000 Injection is used to treat various types of cancers. The detailed uses of Celofos 2000 Injection are as follows:

  • Treats blood cancer:Celofos 2000 Injection helps in managing cancers like leukemia and lymphoma by stopping the growth of cancer cells.
  • Treats breast, ovarian, and pancreatic cancer:Celofos 2000 Injection is effective in slowing the progression of these solid tumors.
  • Treats non-small cell lung cancer:Celofos 2000 Injection helps control and reduce the spread of lung cancer.
  • Treats testicular cancer:Celofos 2000 Injection is used to manage and shrink tumors in the testes.
  • Protects the bladder:Celofos 2000 Injection contains mesna, which prevents bladder toxicity and reduces the risk of haemorrhagic cystitis caused by ifosfamide treatment.

Key Benefits

Celofos 2000 Injection belongs to the group of medicines called antineoplastic agents. Celofos 2000 Injection is a combination of two drugs, Ifosfamide (antineoplastic agent) and mesna (cytoprotectants), used to treat different kinds of cancers such as blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer, and pancreatic cancer. Celofos 2000 Injection works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication. Mesna is used along with ifosfamide to protect the bladder from toxic side effects, particularly haemorrhagic cystitis.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Celofos 2000 Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Celofos 2000 Injection Works

Celofos 2000 Injection contains Ifosfamide (an antineoplastic agent) and mesna (cytoprotectant). Ifosfamide damages the genetic material (DNA and RNA) of cancer cells, stopping their growth and multiplication. Mesna is used along with ifosfamide to protect the bladder from toxic side effects, particularly haemorrhagic cystitis.
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Alcohol

Unsafe

Avoid alcohol consumption while treatment with Celofos 2000 Injection as it may cause unpleasant side effects.

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Pregnancy

Unsafe

Celofos 2000 Injection is not recommended to be used in pregnancy as it may cause serious side effects. Use effective birth control measures during treatment with Celofos 2000 Injection and for 6 months after completing the treatment. Inform your doctor If you get pregnant while you are receiving Celofos 2000 Injection.

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Breast Feeding

Unsafe

Celofos 2000 Injection is excreted in breast milk. Ifosfamide has been demonstrated to produce significant adverse effects and tumours in animal tests. It is essential to consider the importance of the medicine to the mother before discontinuing nursing. Ifosfamide should not be taken by women who are breastfeeding.

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Driving

Caution

Some patients may experience blurred vision or dizziness after using this $ name. If you experience any of these symptoms during treatment, do not drive a vehicle or operate heavy machinery.

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Liver

Caution

There were no official investigations undertaken on patients with liver impairment. Celofos 2000 Injection is metabolized extensively in the liver, producing both beneficial and harmful metabolites. It should be administered with caution to patients with poor liver function.

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Kidney

Caution

There were no official studies undertaken on people with kidney impairment. The kidneys eliminate Celofos 2000 Injection and metabolites but may accumulate in plasma with impaired renal function. Patients with renal impairment should be continuously watched for toxicity, and dose reduction may be necessary.

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Children

Caution

Celofos 2000 Injection is not recommended for use in children under 12 years of age as its safety and efficacy have not been established.

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Heart

Caution

Please inform your doctor if you have heart problems before receiving Celofos 2000 Injection, as there is limited information available on its safety in such cases.

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Geriatrics

Caution

Please inform your doctor if you are geriatric before receiving Celofos 2000 Injection, as there is limited information available on its safety in this age group.

What if I have taken an overdose of Celofos 2000 Injection

Since the doctor or nurse will administer the medication, the risk of overdose is minimal. However, in the case of any accidental overdose, it is essential to contact the doctor immediately for prompt care and ensure the patient is closely monitored.

Diet & Lifestyle Advise

  • Eat protein-rich, low-fat foods like eggs, Greek yoghurt, seafood, lean meats, poultry, beans, soy products, and unsalted nuts.
  • Include vitamin A-rich foods like carrots, sweet potatoes, kale, spinach, and apricots.
  • Avoid intake of fatty, fried, spicy, and overly sweet foods to avoid nausea.
  • Practise good hygiene by staying away from crowded places, and avoiding raw and undercooked food to reduce the risk of infection.
  • Avoid refined sugars and carbohydrates, as tumours often use glucose for energy.
  • Avoid consumption of alcohol and quit smoking.
  • Empty your bladder frequently within 24 hours of chemotherapy; inform your doctor if you experience pain during urination.
  • Get at least 8 hours of sleep and rest regularly.

Have a query?

How Soon It Starts Working

The time required for Celofos 2000 Injection to start to work: The onset of time for Celofos 2000 Injection is clinically unknown. The time for which the effects of Celofos 2000 Injection last: The duration of Celofos 2000 Injection effect is clinically unknown.

What if you forget to take Celofos 2000 Injection

As this medicine will be administered in a hospital by your healthcare professional, the chances of missing a dose are less or minimal. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight. • Keep Celofos 2000 Injection out of reach and sight of children. • Cold chain - To be stored in cold places at 2ºC to 8ºC.
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Keep Refrigerated. Do not freeze.

Drug Warnings

Celofos 2000 Injection should not be administered to individuals if they are allergic to it or its ingredients. Women of childbearing age should use effective birth control during treatment and for at least six months after the last dose to avoid pregnancy. Regular urine and blood tests, including CBC, are required to monitor blood cell counts while receiving Celofos 2000 Injection. Celofos 2000 Injection is not intended for use in conditions like haematuria due to thrombocytopenia or other underlying diseases. It may cause blurry vision and dizziness; therefore, avoid driving or operating heavy machinery while treating with Celofos 2000 Injection. Inform your doctor if you have a history of kidney, heart, liver disease, cystitis, or CNS toxicity before starting therapy with Celofos 2000 Injection. Avoid the consumption of alcohol as it may cause interactions and lead to unpleasant side effects. Celofos 2000 Injection is unsafe during pregnancy and breastfeeding. Patients with infections should exercise caution, and chemotherapy may be temporarily stopped if fever or signs of infection occur. Celofos 2000 Injection may cause bone marrow suppression, decreasing white blood cells and platelets, so regular monitoring is essential.

Drug-Drug Interactions

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Drug-Drug Interactions: Celofos 2000 Injection may interact with antibiotics (fluconazole, ketoconazole, rifampin), antiepileptic drugs (phenobarbitone, phenytoin), calcium channel blockers (diltiazem), antimetabolites (cisplatin), anti-coagulants (anisindione, warfarin, dicumarol).

Drug-Food Interactions: Celofos 2000 Injection may interact with grapefruit, St. John's wort and alcohol, increasing the risk of side effects.

Drug-Disease Interactions: Inform your doctor if you have heart diseases, liver diseases, kidney diseases, bone marrow suppression, CNS toxicity, cystitis, infections and autoimmune disorders like rheumatoid arthritis (pain and inflammation in the joints), systemic lupus erythematosus (a severe form of lupus in which pain and fatigue occur in joints), or nephritis (a type of kidney problem).

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Celofos 2000 Injection belongs to the group of medications called antineoplastic agents. It is used to treat blood cancer, breast cancer, non-small cell lung cancer, ovarian cancer, testicular cancer and pancreatic cancer.

Celofos 2000 Injection is an antineoplastic agent. It works by damaging the DNA of cancer cells, preventing their growth and spread. Mesna is used along with ifosfamide to protect the bladder from toxic side effects, particularly haemorrhagic cystitis.

Celofos 2000 Injection may cause diarrhoea as a common side effect. If you experience this symptom, drink plenty of fluids to stay hydrated, eat non-spicy food, get plenty of rest, and take probiotics. Do not take anti-diarrheal medicines on your own without a doctor’s advice.

The side effects of Celofos 2000 Injection include nausea, diarrhoea, vomiting, loss of appetite, headache, dizziness, hair loss, abdominal pain, pain or redness at the injection site, fever, sore throat, and cough. Most of these side effects will resolve gradually over time and do not require medical attention. However, consult the doctor if you experience these side effects persistently.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - CEL0375
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