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CELRIM TZ INJECTION 1.25GM
CELRIM TZ INJECTION 1.25GM
Manufacturer/Marketer
BIOCON LIMITED
Composition
CEFEPIME-1000MG + TAZOBACTAM-125MGConsume Type
PARENTERAL
In Stock
Prescription RequiredAbout CELRIM TZ INJECTION 1.25GM
CELRIM TZ INJECTION 1.25GM belongs to the class of medications called ‘antibiotics’ used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.
CELRIM TZ INJECTION 1.25GM is a combination of two medicines: Cefepime and Tazobactam. Cefepime is a cephalosporin antibiotic. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis. Tazobactam is a beta-lactamase inhibitor. It can improve the spectrum of antibacterial action by inhibiting the action of beta-lactamase. Beta-lactamase is an enzyme produced by bacteria that can destroy antibiotics (cefotaxime). CELRIM TZ INJECTION 1.25GM is only used to treat bacterial infections and is not recommended for viral infections.
CELRIM TZ INJECTION 1.25GM will be administered by a healthcare professional; do not self-administer. The common side effects of CELRIM TZ INJECTION 1.25GM are pain and swelling at the injection site and skin rash. These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.
It is not recommended to take CELRIM TZ INJECTION 1.25GM if you are allergic to penicillin, any cephalosporin antibiotic, or its contents. Before taking CELRIM TZ INJECTION 1.25GM, inform your doctor if you have kidney problems, diabetes, gastrointestinal problems, especially colitis (inflammation of the large intestine), or use other antibiotics. Do not discontinue or abruptly stop using CELRIM TZ INJECTION 1.25GM as it may lead to antibiotic resistance (bacteria become resistant to antibiotics). CELRIM TZ INJECTION 1.25GM should be used with caution in children, pregnant women, breastfeeding mothers and elderly people. CELRIM TZ INJECTION 1.25GM may interact with alcohol. CELRIM TZ INJECTION 1.25GM may not affect your ability to drive.
Uses of CELRIM TZ INJECTION 1.25GM
Bacterial infections
Medicinal Benefits
CELRIM TZ INJECTION 1.25GM contains Cefepime and Tazobactam. Cefepime is a cephalosporin antibiotic, whereas Tazobactam is a beta-lactamase inhibitor. CELRIM TZ INJECTION 1.25GM has broad-spectrum activity and is effective against both gram-positive and gram-negative bacteria. It makes the drug effective in multiple moderate to severe bacterial infections such as urinary tract infections (UTI), skin infections, intra-abdominal infections, lower respiratory tract (lung) infections such pneumonia (inflammation of the air sacs present in lungs) and bronchitis (inflammation of the bronchi), septicemia (including infections of the bloodstream), and empiric treatment in febrile neutropenic patients (development of fever in patients with low neutrophil count).
Directions for Use
Storage
Side Effects of CELRIM TZ INJECTION 1.25GM
- Pain at the injection site
- Swelling at the injection site
- Skin rash
- Diarrhea
- Nausea
- Vomiting
- Headache
In-Depth Precautions and Warning
Drug Warnings
CELRIM TZ INJECTION 1.25GM should be used with caution in patients with kidney impairment. There is a risk of serious adverse events such as confusion, hallucinations, stupor (a state of near-unconsciousness), and seizures (fits). CELRIM TZ INJECTION 1.25GM may cause Clostridium difficile-associated diarrhoea (CDAD), ranging from mild diarrhea to fatal colitis (inflammation of the large intestine). If CDAD is suspected or confirmed, the doctor may discontinue therapy and advise appropriate fluid and electrolyte management, protein supplementation, and antibiotic therapy to treat CDAD. A CELRIM TZ INJECTION 1.25GM may cause positive direct Coomb’s test, which indicates antibodies against red blood cells. So, it is necessary to let your doctor know that you are taking this medicine before undergoing laboratory tests. Do not discontinue or abruptly stop the medication as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics. CELRIM TZ INJECTION 1.25GM may cause superinfection (additional infection caused by other microbes) on prolonged use.
Drug Interactions
Drug-Drug Interactions: CELRIM TZ INJECTION 1.25GM may interact with aminoglycoside antibiotics (streptomycin, neomycin, and gentamicin) as it may cause severe nephrotoxicity (damage to the kidney). It may also interact with a medicine used to treat gout (probenecid).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: CELRIM TZ INJECTION 1.25GM should be used with caution in patients with kidney problems, gastrointestinal problems, especially colitis (inflammation of the large intestine) and diabetes.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionCELRIM TZ INJECTION 1.25GM may interact with alcohol. Consult your doctor before consuming any alcohol.
Pregnancy
cautionCELRIM TZ INJECTION 1.25GM is a category B medicine and may not cause harmful effects to the unborn baby. However, it should be used in pregnant women only if prescribed by a doctor.
Breast Feeding
cautionCELRIM TZ INJECTION 1.25GM may pass into breast milk in small amounts. So, caution should be exercised when given to breastfeeding mothers.
Driving
safe if prescribedCELRIM TZ INJECTION 1.25GM may not affect your ability to drive.
Liver
cautionCELRIM TZ INJECTION 1.25GM should be used with caution in patients with live diseases. The dose may have to be adjusted by your doctor.
Kidney
cautionCELRIM TZ INJECTION 1.25GM should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.
Children
cautionCELRIM TZ INJECTION 1.25GM is not recommended for infants below two months of age. CELRIM TZ INJECTION 1.25GM is probably safe when used in children above two months. However, the doctor may have to adjust the dose based on age, body weight and medical history.
Habit Forming
Diet & Lifestyle Advise
- Probiotics should be taken after taking the full course of CELRIM TZ INJECTION 1.25GM to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha and kimchi can help restore the intestine's good bacteria.
- Include more fiber-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet.
- Avoid alcoholic beverages can make you dehydrated and also affect your sleep. This can make it harder for your body to aid the antibiotic in fighting off infections.
Special Advise
- CELRIM TZ INJECTION 1.25GM may cause positive Coomb’s test, increase liver enzymes, alter red blood cell count, decrease phosphorus and cause abnormal prothrombin time (PT) and partial thromboplastin time (PTT) (abnormal PT and PTT indicate abnormal blood clotting). So, it is necessary to let your doctor know that you are taking CELRIM TZ INJECTION 1.25GM before undergoing laboratory tests.
- If you are taking aminoglycoside antibiotics such as streptomycin and gentamicin, your kidney function should be regularly monitored.
Other Information (CEL0122)
This item is Not Returnable.
Expires on or after - May-23
Patients Concern
Disease/Condition Glossary
Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. It can target any organ of the body and multiply very quickly. Many give off chemicals called toxins, which can damage tissue and make you sick. Bacterial infections vary from minor illnesses (like sore throat and ear infections) to severe brain infections (like meningitis and encephalitis). When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Few harmful bacteria that commonly cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can get a bacterial infection, but people with a weak immune system or taking immunosuppressive medicines like steroids are more prone to infections.
FAQs
How does CELRIM TZ INJECTION 1.25GM work?
Are there any side-effects of CELRIM TZ INJECTION 1.25GM?
In which conditions should I avoid taking CELRIM TZ INJECTION 1.25GM?
Does CELRIM TZ INJECTION 1.25GM cause diarrhea?
I am allergic to penicillin, can I take CELRIM TZ INJECTION 1.25GM?
PRODUCT SUBSTITUTES
CELRIM TZ INJECTION 1.25GM
Country Of Origin
INDIA
Manufacturer/Marketer address
20th KM, Hosur Road, Electronic City, Bangalore, India - 560 100
Disclaimer
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Vial
1 Injection in 1 Vial