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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Choltran 5mg Tablet is used to treat high cholesterol levels. It supports healthy cholesterol balance by lowering harmful cholesterol levels, thereby protecting the heart and blood vessels. It also treats itching caused by partial biliary obstruction. It also helps relieve diarrhoea caused by excess bile acids in people with short bowel syndrome.

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Composition :

CHOLESTYRAMINE-5MG

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Choltran 5mg Tablet

Choltran 5mg Tablet is used to lower bad cholesterol levels, thereby reducing the risk of heart attack and stroke in future. It also treats itching caused by a biliary obstruction. Choltran 5mg Tablet may also be used to treat diarrhoea caused by excess bile acids in people with short bowel syndrome.

Choltran 5mg Tablet contains Cholestyramine, which binds to bile acids in the intestine and helps remove them from the body through the stools. This process causes the liver to use more cholesterol to produce new bile acids, thereby lowering levels of bad cholesterol (LDL) in the blood.

Take Choltran 5mg Tablet as instructed by your doctor. Some people may experience constipation, nausea, vomiting, diarrhoea, stomach pain or gas. Most of the side effects do not require medical attention and resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Choltran 5mg Tablet or any other medicines, please tell your doctor. Before taking Choltran 5mg Tablet, please consult a doctor if you are pregnant or breastfeeding. Choltran 5mg Tablet is not recommended for children below 6 years of age, as the safety and effectiveness have not been established.

Uses of Choltran 5mg Tablet

Choltran 5mg Tablet is used in the treatment of Hyperlipidemia (high cholesterol). The detailed uses of Choltran 5mg Tablet are as follows:

  • High Cholesterol: Choltran 5mg Tablet is used to lower elevated cholesterol levels, particularly low-density lipoprotein (LDL) or 'bad' cholesterol.
  • Treats itching caused by liver disease: It helps relieve itching in people with partial biliary obstruction by removing excess bile acids from the body.
  • Manages diarrhoea due to bile acid malabsorption: It is effective in treating diarrhoea caused by conditions like Crohn’s disease or after gallbladder removal.

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Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Choltran 5mg Tablet should be administered orally after mixing with milk, water or fruit juices. Stir well and swallow the mixture slowly. Do not store it for later use.
  • Do not mix it with very hot or cold liquids.

Medicinal Benefits

Management of High Cholesterol:

  • Helps lower bad cholesterol (LDL) levels in the blood.
  • Supports healthy cholesterol balance when used along with dietary changes.
  • Helps lower the risk of heart attack and other cardiovascular complications.
  • Helps prevent excess cholesterol deposition in blood vessels supplying the brain.

Bile Acid–Induced Diarrhoea:

  • Provides symptomatic relief from bile acid–induced diarrhea in patients with short bowel syndrome.

Relief from Itching (Pruritus):

  • Helps relieve itching associated with partial biliary obstruction.

How Choltran 5mg Tablet Works

Choltran 5mg Tablet contains Cholestyramine, which works by binding to bile acids, aiding fat digestion in the intestine and preventing its reabsorption into the bloodstream, thereby excreting it via faeces. This, in turn, triggers the liver to produce more bile acids from the blood's cholesterol and decreases bad cholesterol (LDL) levels in the blood. Thus, Choltran 5mg Tablet reduces the risk of stroke or heart attack by reducing the brain's excess cholesterol deposition and the heart's major blood vessels.

Storage

• Store in a cool and dry place away from sunlight.• Keep Choltran 5mg Tablet out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Choltran 5mg Tablet

An overdose of Choltran 5mg Tablet may cause severe stomach pain or constipation. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are allergic to Choltran 5mg Tablet or any other medicines, please tell your doctor.
  • Before taking Choltran 5mg Tablet, please consult a doctor if you are pregnant or breastfeeding.
  • Choltran 5mg Tablet is not recommended for children below 6 years of age, as the safety and effectiveness have not been established.
  • Avoid taking Choltran 5mg Tablet if you have gallstones or a blockage in the stomach or intestines.
  • If you have diabetes, thyroid disorder, kidney, liver or heart problems, inform your doctor before taking Choltran 5mg Tablet.
  • You are recommended to take other medicines 1 hour before or 4 to 6 hours after taking Choltran 5mg Tablet, as taking them at the same time may reduce the effectiveness of other medicines.
  • Let your doctor know if you are taking any other medicines.

Diet & Lifestyle Advise

Healthy Diet:

  • Maintain a low-fat diet and limit whole milk dairy products and red meat.
  • Prefer skim milk and fat-free or low-fat dairy options.
  • Include fruits, vegetables, fish, poultry, whole grains, and nuts in your diet.
  • Reduce intake of sugary drinks, processed foods, and high-calorie snacks.

Physical Activity:

  • Do regular exercise such as swimming, cycling, walking, or dancing.
  • Focus on losing excess weight, as obesity increases bad cholesterol and lowers good cholesterol.

Lifestyle Habits:

  • Avoid smoking to protect heart and blood vessel health.
  • Limit or avoid alcohol consumption to help maintain healthy cholesterol levels.

Habit Forming

No

Therapeutic Class

BILE ACID SEQUESTRANTS

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Alcohol

Caution

Interaction of Choltran 5mg Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Choltran 5mg Tablet.

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Pregnancy

Caution

Choltran 5mg Tablet is a category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks. However, please consult a doctor if you are pregnant.

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Breast Feeding

Caution

It is unknown whether Choltran 5mg Tablet is excreted in human milk. Therefore, please consult a doctor if you are breastfeeding. Choltran 5mg Tablet is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Safe

Choltran 5mg Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Choltran 5mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Choltran 5mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Choltran 5mg Tablet is not recommended for children below 6 years of age. However, Choltran 5mg Tablet should be used with caution in children above 6 years if recommended by a doctor.

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Heart

Safe if suggested

Choltran 5mg Tablet can be used in heart patients if suggested by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Caution

Choltran 5mg Tablet can be given in elderly patients with extreme caution, due to the increased risk of gastrointestinal problems.

FAQs

Choltran 5mg Tablet is used to lower bad cholesterol levels, thereby‚ reducing the risk of heart attack and stroke in future. It may also be used to help stop some types of diarrhoea or itching.

Choltran 5mg Tablet contains Cholestyramine that binds to bile acids (helps in the digestion of fats consumed in the diet) in the intestine and removes them from the body. This makes the liver produce more bile acids from the cholesterol in the blood and decreases cholesterol levels. Also, Choltran 5mg Tablet reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart.

You are not recommended to take Choltran 5mg Tablet with levothyroxine at the same time as it may reduce the absorption of levothyroxine and decrease its effectiveness. Therefore, you are recommended to take levothyroxine after 4 hours of taking Choltran 5mg Tablet. However, please consult a doctor before taking Choltran 5mg Tablet with any other medicines.

Choltran 5mg Tablet may be used to treat certain types of diarrhoea, such as bile acid diarrhoea, in which excess bile acids spill into the large intestine and trigger watery and loose stools. However, please consult a doctor before taking Choltran 5mg Tablet.

Choltran 5mg Tablet decreases the absorption of certain vitamins, such as fat-soluble vitamins (A, D and K), by the body, especially when taken in high doses or for long periods. Therefore, your doctor may recommend that you take vitamin supplements with Choltran 5mg Tablet.

You are not recommended to stop taking Choltran 5mg Tablet without consulting your doctor, as it may worsen the condition and increase the risk of heart attack and stroke. Therefore, take Choltran 5mg Tablet for as long as your doctor has recommended it, and if you experience any difficulty while taking Choltran 5mg Tablet, please consult your doctor so that the dose may be gradually reduced.

Choltran 5mg Tablet may cause constipation as a common adverse effect. You are advised to drink plenty of fluids while taking Choltran 5mg Tablet to prevent constipation. However, if the condition persists or worsens, please consult a doctor.

Choltran 5mg Tablet may cause side effects such as nausea, vomiting, diarrhoea, constipation, stomach pain or flatulence (gas). If these side effects persist or worsen, please consult your doctor.

Choltran 5mg Tablet should be avoided by patients with a blockage in the stomach or intestines. If you have any concerns, consult your doctor.

Cholesterol is a waxy fat, or lipid, which circulates throughout the body in blood. The liver makes cholesterol, but it can also be obtained from foods. There are two types of cholesterol, HDL (high-density lipoprotein) or the good cholesterol and LDL (low-density lipoprotein) or the bad cholesterol.

LDL (low-density lipoprotein) is called bad cholesterol as it accumulates cholesterol in the blood. This leads to blockage in the heart and is a direct cause of strokes, heart attacks, and peripheral artery disease.

HDL (high-density lipoprotein) is also called as good cholesterol as it transports cholesterol from blood to liver for elimination. Thus, lowers the risk of heart diseases.

You can book a lipid profile test with any recognised laboratory. With the help of this test, you can monitor your total cholesterol, triglycerides, HDL levels, LDL levels, and the ratio between cholesterol and HDL. Before giving your blood sample to the laboratory, you may need to fast for a period of 10-12 hours. After receiving your test report, consult a doctor to help you evaluate your test results.

The total cholesterol level should be 125 to 200 mg/dL, HDL should be 40mg/dL or higher and LDL should be less than 100 mg/dL.

If you have high cholesterol, it accumulates upon the artery walls. This narrows arteries and thus reduces blood flow to the heart. This can result in heart attack or stroke.

When your cholesterol levels are high enough (LDL level greater than 190mg/dL) to increase your risk for heart disease or if you already have a history of stroke or heart attack, medication is usually suggested. Always consult your doctor before taking any medicines.

Some of the symptoms of high cholesterol include pain in the neck, jaw, upper abdomen, or back; chest pain; difficulty breathing; extreme fatigue; and numbness or coldness in extremities.

Some of the foods that are high in cholesterol are red meat like pork, lamb, packaged food, full-fat dairy, fried foods, processed meat (sausage, bacon), etc.

In addition to taking Choltran 5mg Tablet, following a low-fat diet, reducing body weight, regular exercise, and limiting alcohol consumption can help improve the effectiveness of Choltran 5mg Tablet and lower cholesterol levels.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India.
Other Info - CHOL214

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