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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cidonat 375 mg Injection 5 ml is used in the treatment of cytomegalovirus (CMV) retinitis. It contains Cidofovir, which works by inhibiting the CMV polymerase enzyme responsible for viral DNA synthesis. It works by slowing the growth of the cytomegalovirus. Thus, it helps treat Cytomegalovirus (CMV) retinitis. This medicine is contraindicated in patients with renal insufficiency and patients who cannot receive probenecid or other sulfa-containing products. This medicine should not be used for conditions other than CMV retinitis.

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Whats That

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Composition :

CIDOFOVIR-75MG/ML

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Cidonat 375 mg Injection 5 ml

Cidonat 375 mg Injection 5 ml is an antiviral medicine used in the treatment of cytomegalovirus (CMV) retinitis. Cytomegalovirus (CMV) retinitis is a viral infection that affects the retina of the eye caused by a virus called Cytomegalovirus (CMV), especially in AIDS patients. It is a serious infection that can lead to blindness. Cidonat 375 mg Injection 5 ml is used in combination with oral probenecid.

Cidonat 375 mg Injection 5 ml contains Cidofovir, which works by inhibiting the CMV polymerase enzyme responsible for viral DNA synthesis. It works by slowing the growth of the cytomegalovirus. Thus, it helps treat Cytomegalovirus (CMV) retinitis.

Cidonat 375 mg Injection 5 ml may cause certain side effects such as nausea, vomiting, headache, hair loss, rash, weakness, fever, inflammation of the eye, shortness of breath, diarrhoea, chills, and pain at the injection site. These side effects may not occur in every patient using this medication and gradually resolve over time. If the side effects persist longer or worsen, please inform your doctor. A healthcare professional will administer Cidonat 375 mg Injection 5 ml; hence, do not self-administer.

Cidonat 375 mg Injection 5 ml should be avoided if you are allergic to it. This medicine is contraindicated in patients with renal insufficiency and patients who cannot receive probenecid or other sulfa-containing products. This medicine should not be used for conditions other than CMV retinitis. Let your doctor know about your complete medical and medication history to rule out any interactions. Inform your doctor if you have a weakened immune system, an electrolyte imbalance, diabetes, and liver or kidney diseases before starting the use of Cidonat 375 mg Injection 5 ml. Cidonat 375 mg Injection 5 ml is not recommended for use in pregnant and breastfeeding women.

Uses of Cidonat 375 mg Injection 5 ml

Cidonat 375 mg Injection 5 ml is used in the treatment of Cytomegalovirus (CMV) retinitis. The detailed use of Cidonat 375 mg Injection 5 ml is as follows:<br/>• Cytomegalovirus (CMV) Retinitis in AIDS Patients: Cidonat 375 mg Injection 5 ml helps slow the progression of CMV-related vision loss in people with AIDS.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Cidonat 375 mg Injection 5 ml will be administered by a nurse or doctor.• Do not self-administer.

Medicinal Benefits

Cidonat 375 mg Injection 5 ml treats viral infection of the eye caused by Cytomegalovirus (CMV) retinitis. Cidonat 375 mg Injection 5 ml consists of Cidofovir, which works by inhibiting the CMV polymerase enzyme responsible for viral DNA synthesis. It helps kill the virus and eventually stop the growth of the cytomegalovirus. Thus, helps to treat Cytomegalovirus (CMV) retinitis. This medicine is only used in treating CMV retinitis but is not used for other conditions. It does not help in treating HIV infection.

How Cidonat 375 mg Injection 5 ml Works

Cidonat 375 mg Injection 5 ml contains Cidofovir, which works by inhibiting the CMV polymerase enzyme responsible for viral DNA synthesis. It works by slowing the growth of the cytomegalovirus. Thus, it helps treat Cytomegalovirus (CMV) retinitis.

Storage

• Store in a cool and dry place away from sunlight.• Keep Cidonat 375 mg Injection 5 ml out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Cidonat 375 mg Injection 5 ml

As Cidonat 375 mg Injection 5 ml is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Cidonat 375 mg Injection 5 ml may cause a change in the amount of urine.

Drug Warnings

Cidonat 375 mg Injection 5 ml should be avoided if you are allergic to it. Let your doctor know about your medical history and medication history to rule out any interactions. This medicine is contraindicated in patients with renal insufficiency, patients who cannot receive probenecid or other sulfa-containing products, and the use of Cidonat 375 mg Injection 5 ml in conditions other than CMV retinitis. Inform your doctor if you have a weakened immune system, an electrolyte imbalance, diabetes, and liver or kidney diseases before starting Cidonat 375 mg Injection 5 ml. Cidonat 375 mg Injection 5 ml is not recommended for use in pregnant and breastfeeding women. Hence, inform your doctor before starting Cidonat 375 mg Injection 5 ml.  Cidonat 375 mg Injection 5 ml may cause nephrotoxicity, haematological toxicity, decreased intraocular pressure, and metabolic acidosis in some patients. Hence, patients should be monitored carefully for any changes during the treatment. Cidonat 375 mg Injection 5 ml is not recommended for use in children below 16 years of age as the safety and efficacy are not established. Avoid driving and operating machines, as it can cause fatigue and dizziness.

Diet & Lifestyle Advise

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Know your allergy triggers, such as pollen, dust and other factors.
  • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
  • Try to drink plenty of water to keep your body hydrated.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Cidonat 375 mg Injection 5 ml Substitute

Substitutes safety advice
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Alcohol

Consult your doctor

There is limited information on how alcohol consumption affects Cidonat 375 mg Injection 5 ml. Please consult your doctor.

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Pregnancy

Unsafe

Cidonat 375 mg Injection 5 ml may cause fetal toxicity and impairment of fertility in males and females. Hence, inform your doctor if you are pregnant before receiving Cidonat 375 mg Injection 5 ml.

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Breast Feeding

Unsafe

Cidonat 375 mg Injection 5 ml is not recommended for use in nursing mothers as it can cause serious side effects to newborn infants. Hence, inform your doctor if you are breastfeeding.

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Driving

Unsafe

Cidonat 375 mg Injection 5 ml may cause fatigue and drowsiness. Hence, do not drive or operate machinery that requires mental alertness until you are not alert.

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Liver

Caution

Inform your doctor if you have any history of liver diseases or hepatic impairment before receiving Cidonat 375 mg Injection 5 ml. Your doctor will advise this medicine only if the benefits outweigh the risks.

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Kidney

Caution

Cidonat 375 mg Injection 5 ml is known to cause kidney damage. Hence, inform your doctor if you have any history of kidney problems before receiving Cidonat 375 mg Injection 5 ml. This medicine is contraindicated in patients with severe renal disease or renal insufficiency.

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Children

Unsafe

The use of Cidonat 375 mg Injection 5 ml is not recommended for children below 18 years of age as the safety and efficacy data are not established.

Have a query?

FAQs

Cidonat 375 mg Injection 5 ml is used to treat Cytomegalovirus (CMV) retinitis.

Cidonat 375 mg Injection 5 ml works by inhibiting the CMV polymerase enzyme responsible for viral DNA synthesis.

No,Cidonat 375 mg Injection 5 ml will be administered by the trained healthcare professional. Do not self-administer it.

Inform your doctor if you are pregnant or a nursing mother before starting treatment with Cidonat 375 mg Injection 5 ml. Maintain caution if you have kidney, liver, or blood disorders, a weakened immune system, diabetes, or an electrolyte imbalance, as it may worsen your condition. Your doctor will administer Cidonat 375 mg Injection 5 ml only when the benefits outweigh the risks.

Country of origin

India

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - CID0082

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