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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Ciplox-D Eye/Ear Drops contains a combination of three medicines used to treat bacterial ear and eye infections such as post-operative inflammatory conditions of the eyes, acute otitis media, and acute otitis externa. This medicine stops the growth of bacteria by inhibiting the DNA-gyrase enzyme and thereby helps reduce bacterial eye infections. This medicine is not effective for treating viral infections. Sometimes, you may experience certain common side effects, such as eye discomfort, irritation, eye/ear pain, and stinging sensation.
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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

EYE/EAR

Return Policy :

Not Returnable

Expires on or after :

About Ciplox-D Eye/Ear Drops

Ciplox-D Eye/Ear Drops is used to treat bacterial eye infections, post-operative inflammatory conditions of the eyes, acute otitis media (middle ear infections) and acute otitis externa (inflammation of the ear canal). Bacterial eye infection is associated with the inflammation or infection of the conjunctiva (white part of the eye) and the inner eyelid. An ear infection occurs when the bacteria affect the middle or outer ear, leading to pain and inflammation.
 
Ciplox-D Eye/Ear Drops is a combination of three drugs: Ciprofloxacin, Dexamethasone, and Benzalkonium chloride. Ciprofloxacin kills the infection-causing bacteria by inhibiting the synthesis of enzymes necessary for the survival of bacteria. Dexamethasone blocks the chemical messengers that cause swelling, itching, and redness. Benzalkonium chloride acts as a preservative. Thereby, Ciplox-D Eye/Ear Drops helps in treating bacterial infections of the eye and ear.
 
You are advised to use Ciplox-D Eye/Ear Drops for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Ciplox-D Eye/Ear Drops may cause common side effects such as discomfort, irritation, stinging sensation, and redness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Talk to your doctor if the irritation persists despite using Ciplox-D Eye/Ear Drops for a week or if it worsens. Consult your doctor if you are pregnant or breastfeeding. Ciplox-D Eye/Ear Drops should be used in children only if prescribed by the doctor. Do not touch the tip of the dropper, as it may contaminate the contents. Keep your doctor informed regarding your health condition and the medicines you are taking to prevent any side effects/interactions.

Uses of Ciplox-D Eye/Ear Drops

Treatment of Bacterial eye infections, post-operative inflammatory condition of the eyes, acute otitis media (middle ear infections) and acute otitis externa (inflammation of the ear canal)

Directions for Use

Eye drops: Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.Ear drops: Lie down with the affected ear facing upwards. Hold the dropper over the ear and instil the prescribed number of drops into the ear.

Medicinal Benefits

Ciplox-D Eye/Ear Drops is a combination of three drugs: Ciprofloxacin, Dexamethasone, and Benzalkonium chloride. Ciplox-D Eye/Ear Drops is used to treat bacterial eye infections, post-operative inflammatory conditions of the eyes, acute otitis media (middle ear infections) and acute otitis externa (inflammation of the ear canal). Dexamethasone is a corticosteroid that blocks the chemical messengers that cause swelling, itching, and redness. Ciprofloxacin is an anti-bacterial agent that kills bacteria by preventing the synthesis of essential proteins required for the survival of the bacteria. Benzalkonium chloride acts as a preservative. Together, Ciplox-D Eye/Ear Drops helps in treating bacterial infections of the eye/ear.

How Ciplox-D Eye/Ear Drops Works

Ciplox-D Eye/Ear Drops is a combination of three drugs: Ciprofloxacin, Dexamethasone, and Benzalkonium chloride. Ciprofloxacin kills the infection-causing bacteria by inhibiting the synthesis of enzymes necessary for the survival of bacteria. Dexamethasone blocks the chemical messengers that cause swelling, itching, and redness. Benzalkonium chloride acts as a preservative. Thereby, Ciplox-D Eye/Ear Drops helps in treating bacterial infections of the eye and ear.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Ciplox-D Eye/Ear Drops

Though it is unlikely to cause any harm if you have overdosed, it is advised not to exceed the recommended dose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Do not use Ciplox-D Eye/Ear Drops if you are allergic to any of its contents. Avoid using Ciplox-D Eye/Ear Drops if you have tuberculosis, damaged cornea, ulceration, lesions with incomplete formation of the covering tissue, increased intraocular pressure, allergy to steroids, viral ear infections, herpes simplex, fungal or parasitic ear infection. Inform your doctor if you have high closed-angle glaucoma, high blood pressure, ocular hypertension, diabetes, eye infection or injury, hyperthyroidism, heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Ciplox-D Eye/Ear Drops should be used in children only if prescribed by the doctor.

Drug-Drug Interactions

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CiprofloxacinHalofantrine
Critical
CiprofloxacinAmiodarone
Critical

Drug-Drug Interactions

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CiprofloxacinHalofantrine
Critical
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Using Ciplox-D Eye/Ear Drops 10 ml with Halofantrine can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Ciplox-D Eye/Ear Drops 10 ml with Halofantrine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
CiprofloxacinAmiodarone
Critical
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Taking Amiodarone and Ciplox-D Eye/Ear Drops 10 ml may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Amiodarone with Ciplox-D Eye/Ear Drops 10 ml is not recommended, it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
CiprofloxacinPimozide
Critical
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
When Ciplox-D Eye/Ear Drops 10 ml is taken with Pimozide, it can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Ciplox-D Eye/Ear Drops 10 ml with Pimozide is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
CiprofloxacinThioridazine
Critical
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Combining Ciplox-D Eye/Ear Drops 10 ml with Thioridazine can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Ciplox-D Eye/Ear Drops 10 ml with Thioridazine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
CiprofloxacinDronedarone
Critical
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
When Dronedarone is taken with Ciplox-D Eye/Ear Drops 10 ml, it can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Ciplox-D Eye/Ear Drops 10 ml with Dronedarone is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
CiprofloxacinCisapride
Critical
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Using Ciplox-D Eye/Ear Drops 10 ml with Cisapride can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Ciplox-D Eye/Ear Drops 10 ml with Cisapride is not recommended, it can be take if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
CiprofloxacinZiprasidone
Critical
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Coadministration of Ciplox-D Eye/Ear Drops 10 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ciplox-D Eye/Ear Drops 10 ml with Ziprasidone is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, confusion, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
CiprofloxacinFlibanserin
Critical
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
When Flibanserin is taken with Ciplox-D Eye/Ear Drops 10 ml, it can cause extreme drowsiness and reduces blood pressure that can lead to dizziness, lightheadedness, fainting.

How to manage the interaction:
Taking Ciplox-D Eye/Ear Drops 10 ml with Flibanserin is not recommended, but it can be taken if prescribed by the doctor. It is advised to take flibanserin at bedtime to reduce the risk of side effects
CiprofloxacinMesoridazine
Critical
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Using Ciplox-D Eye/Ear Drops 10 ml with Mesoridazine can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Ciplox-D Eye/Ear Drops 10 ml with Mesoridazine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
CiprofloxacinProcainamide
Critical
How does the drug interact with Ciplox-D Eye/Ear Drops 10 ml:
Using Ciplox-D Eye/Ear Drops 10 ml with Procainamide can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Ciplox-D Eye/Ear Drops 10 ml with Procainamide is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

Drug-Food Interactions

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BENZALKONIUM CHLORIDE-0.01%W/V+CIPROFLOXACIN-0.3%W/V+DEXAMETHASONE-0.1%W/VCalcium rich foods, Caffeine containing foods/drinks
Moderate

Drug-Food Interactions

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BENZALKONIUM CHLORIDE-0.01%W/V+CIPROFLOXACIN-0.3%W/V+DEXAMETHASONE-0.1%W/VCalcium rich foods, Caffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese, Yogurt, Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Using caffeine together with ciprofloxacin may increase the effects of caffeine. Taking dairy products such as milk, yogurt, or calcium-fortified foods can make the medication less effective. Avoid taking caffeine with ciprofloxacin, as it causes effects. Contact your doctor if you experience headaches, tremors, restlessness, nervousness, insomnia, and increased blood pressure or heart rate. Avoid taking milk, yogurt, or calcium-fortified foods. You could interrupt the feeding for 1 hour before and 2 hours after the ciprofloxacin dose. Do not stop using any medications without talking to your doctor.

Diet & Lifestyle Advise

Eye infections: 

  • Wash your hands regularly. Avoid touching the eyes with dirty hands. 

  • Avoid rubbing the eyes.

  • Avoid sharing eye makeup such as eyeliner, mascara or kohl.

  • Always use clean towels or tissues to wipe your eyes and face.

  • Regularly wash and change the pillowcases.

  • If you wear contact lens: Clean and replace contact lens more often. Never share contact lens. Always remember to wash your hands before inserting and after removing the contact lens. 

  • Avoid staring at digital screens for longer durations. Rest your eyes for every 20 minutes.

  • Blink regularly as it helps in the spread of hydrating substances such as mucus and tears across the eyes.

 

Ear infections: 

  • Include fruits, vegetables, high-quality proteins and whole wheat grains in your diet to strengthen the immune system.

  • Avoid consuming foods that you are allergic to as it can cause the body to produce excess mucus leading to inflammation.

  • Avoid getting things like shampoo, soap, and water into the ear, as it can cause itching.

  • Do not poke or scratch the ear, as it can cause damage to the ear canal, leading to inflammation. The inflamed skin can be infected by bacteria or fungi, which can cause infections in the ear.

  • Stay healthy as immunity prevents infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS
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Alcohol

Caution

It is not known whether Ciplox-D Eye/Ear Drops interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will decide whether Ciplox-D Eye/Ear Drops can be used by breastfeeding mothers or not.

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Driving

Caution

Ciplox-D Eye/Ear Drops may temporarily blur your vision when instilled in the eyes. So, avoid driving or operating machinery until your vision is clear.

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Liver

Caution

Please consult your doctor if you have any concerns regarding the usage of Ciplox-D Eye/Ear Drops in patients with liver impairment.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of Ciplox-D Eye/Ear Drops in patients with kidney impairment.

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Children

Caution

Ciplox-D Eye/Ear Drops should be used in children only if prescribed by the doctor.

FAQs

Ciplox-D Eye/Ear Drops is used to treat bacterial eye infections, post-operative inflammatory conditions of the eyes, acute otitis media (middle ear infections) and acute otitis externa (inflammation of the ear canal).

Ciplox-D Eye/Ear Drops kills the bacteria by preventing the synthesis of essential proteins required for survival of the bacteria. It also blocks the synthesis of chemical messengers that cause irritation. Thereby treats bacterial infections of the eye/ear.

Do not stop using Ciplox-D Eye/Ear Drops on your own. To treat your condition effectually, continue using Ciplox-D Eye/Ear Drops for as long as your doctor has prescribed it. Consult the doctor if the irritation persists or worsens.

Ciplox-D Eye/Ear Drops can be used with other eye/ear medications if prescribed by the doctor. However, maintain a gap of 5-10minutes between Ciplox-D Eye/Ear Drops and other eye/ear medications.

Do not use Ciplox-D Eye/Ear Drops for longer durations unless prescribed as it may lead to other infections. Consult your doctor if your condition worsens or does not improve despite using Ciplox-D Eye/Ear Drops for a week.

If you're taking ciprofloxacin for an infection, you should start feeling better within a few days. However, this depends on the type of infection. If you don't see improvement after 2-3 days or if your symptoms worsen, consult the doctor. They can assess your progress and provide further guidance.

Ciplox-D Eye/Ear Drops should be stored in a cool and dry place away from sunlight. Dispose of the Ciplox-D Eye/Ear Drops and packaging responsibly. Do not flush the medication down the toilet or pour it down the drain.

Eye drops: Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes. Ear drops: Lie down with the affected ear facing upwards. Hold the dropper over the ear and instill the prescribed number of drops into the ear.

Ciplox-D Eye/Ear Drops contains ciprofloxacin, dexamethasone, and benzalkonium chloride. It is used to treat bacterial eye infections, post-operative inflammatory conditions of the eyes, acute otitis media (middle ear infections), and acute otitis externa (inflammation of the ear canal).

The common side effects of Ciplox-D Eye/Ear Drops may include discomfort, irritation, stinging sensation, and redness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Follow your doctor's advice and take the right amount of medicine. Be aware of side effects and take care of yourself. If you're pregnant while on treatment, inform your doctor immediately. Don't take other medications unless instructed by the doctor. Limit or intake of alcohol to avoid unpleasant side effects. Ciplox-D Eye/Ear Drops may temporarily blur your vision when instilled in the eyes. So, avoid driving or operating machinery until your vision is clear. Always follow the doctor's instructions.

Ciplox-D Eye/Ear Drops should be used in children only if prescribed by the doctor. Please consult your doctor before using it in children.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - CIP0024

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