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  1. Home
  2. Medicine

  3. Clacin 500 Tablet

Prescription drug
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Clacin 500 Tablet, Pack of 1 Tablet
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Composition :

CLARITHROMYCIN-500MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Clacin 500 Tablet

Clacin 500 Tablet is used to treat bacterial infections, including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis, and ear infections. Besides this, Clacin 500 Tablet is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori.

Clacin 500 Tablet contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Clacin 500 Tablet helps treat infections.

Clacin 500 Tablet may cause side effects, including nausea, diarrhoea, vomiting, loss of appetite, bloating, indigestion, headaches, and difficulty sleeping. These side effects are temporary and may resolve after some time; however, if they persist, let your doctor know.

Do not take Clacin 500 Tablet if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to prevent any interactions.

Uses of Clacin 500 Tablet

Clacin 500 Tablet is used in the treatment of Bacterial infections. The detailed uses of Clacin 500 Tablet are as follows:

  • Treatment of Respiratory Infections: Clacin 500 Tablet is commonly prescribed to treat respiratory infections such as bronchitis and pneumonia caused by susceptible bacteria.
  • Skin Infections: Clacin 500 Tablet effectively treats skin infections like cellulitis or impetigo, caused by bacterial pathogens.
  • Sinusitis: Clacin 500 Tablet is used to manage acute bacterial sinusitis, relieving symptoms like nasal congestion and facial pain caused by bacterial infections.
  • Otitis Media: Clacin 500 Tablet is frequently utilised to treat middle ear infections (otitis media), providing relief from ear pain and inflammation.

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Directions for Use

  • Clacin 500 Tablet can be taken with or without food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Clacin 500 Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Clacin 500 Tablet is a macrolide class antibiotic used to treat a wide range of bacterial infections.
  • It is effective against both gram-positive and gram-negative bacteria, certain anaerobic organisms, and some parasites such as Balantidium coli and Entamoeba species.
  • It is commonly prescribed for chest and lung infections like bronchitis and pneumonia.
  • It helps treat bacterial skin infections such as cellulitis.
  • It is beneficial in treating middle ear infections and throat infections caused by susceptible bacteria.
  • When used in combination with other drugs, Clacin 500 Tablet aids in eradicating Helicobacter pylori, the bacteria responsible for duodenal ulcers.
  • By stopping the growth and multiplication of bacteria, Clacin 500 Tablet helps clear infections and promotes faster recovery.

How Clacin 500 Tablet Works

Clacin 500 Tablet contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Clacin 500 Tablet helps prevent infections.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Clacin 500 Tablet
  • Drink plenty of fluids and consider oral rehydration solutions.
  • Eat bland, easily digestible foods like bananas, rice, toast, and applesauce.
  • Avoid trigger foods like greasy, spicy, fatty, acidic, and caffeinated foods.
  • Gradually reintroduce fiber-rich foods as symptoms improve.
  • Get adequate sleep and rest.
  • Practice relaxation techniques to manage stress.
  • Maintain regular bowel habits.
  • Avoid overexertion and take breaks when needed.
  • Consult a doctor if your gastrointestinal symptoms are severe, persistent, or accompanied by fever, bloody stools, dehydration, or last for more than a few days.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Clacin 500 Tablet

Do not take more than the prescribed dose of Clacin 500 Tablet as it may cause overdose. The symptoms of overdose include diarrhoea, vomiting, nausea and stomach pain. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Avoid taking Clacin 500 Tablet if you are allergic to any of the components present in it.
  • In some cases, the use of Clacin 500 Tablet causes antibiotic-associated diarrhoea.
  • Clacin 500 Tablet may cause sensitive skin to react to sunlight and ultraviolet rays, leading to an exaggerated sunburn reaction. Hence, it is advisable to apply sunscreen before going outside.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Let your doctor know if you are taking any other medicines, including supplements or herbal products.

Drug-Drug Interactions

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ClarithromycinSilodosin
Critical
ClarithromycinFlibanserin
Critical

Drug-Drug Interactions

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ClarithromycinSilodosin
Critical
How does the drug interact with Clacin 500 Tablet:
Taking Silodosin with Clacin 500 Tablet may significantly increase the blood levels and effects of Silodosin, this may cause blood pressure to fall excessively and heart rate to increase, especially when you rise from a sitting or lying position.

How to manage the interaction:
Co-administration of Clacin 500 Tablet and Silodosin is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, consult a doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not stop using any medications without a doctor's advice.
ClarithromycinFlibanserin
Critical
How does the drug interact with Clacin 500 Tablet:
When Flibanserin is taken with Clacin 500 Tablet, it can slow down the way Flibanserin is broken down in the body.

How to manage the interaction:
Co-administration of Clacin 500 Tablet and Flibanserin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like excessive drowsiness and decreases in blood pressure that can lead to dizziness, lightheadedness, or fainting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinBepridil
Critical
How does the drug interact with Clacin 500 Tablet:
Co-administration of Bepridil with Clacin 500 Tablet may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Clacin 500 Tablet with Bepridil is not recommended as it can result in an interaction, it should be taken only if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinSaquinavir
Critical
How does the drug interact with Clacin 500 Tablet:
When Clacin 500 Tablet is taken with Saquinavir, increases the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Clacin 500 Tablet and Saquinavir can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinNimodipine
Critical
How does the drug interact with Clacin 500 Tablet:
When Nimodipine is taken with Clacin 500 Tablet, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Clacin 500 Tablet and Nimodipine is not recommended as it can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heart rhythm, swelling, and low blood pressure, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinDroperidol
Critical
How does the drug interact with Clacin 500 Tablet:
Co-administration of Droperidol with Clacin 500 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Clacin 500 Tablet with Droperidol can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinErgotamine
Critical
How does the drug interact with Clacin 500 Tablet:
When Ergotamine is taken with Clacin 500 Tablet, the amount of Ergotamine in the blood can go up.

How to manage the interaction:
Taking Clacin 500 Tablet with Ergotamine can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinDronedarone
Critical
How does the drug interact with Clacin 500 Tablet:
When Dronedarone is taken with Clacin 500 Tablet, can increase the blood levels of dronedarone and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Clacin 500 Tablet with Dronedarone can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinColchicine
Critical
How does the drug interact with Clacin 500 Tablet:
Coadministration of colchicine with Clacin 500 Tablet may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Taking Colchicine with Clacin 500 Tablet is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
ClarithromycinPimozide
Critical
How does the drug interact with Clacin 500 Tablet:
Combining Clacin 500 Tablet with Pimozide can increase the risk of heart rhythm problems.

How to manage the interaction:
Co-administration of Clacin 500 Tablet and Pimozide can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heartbeat, chest tightness, blurred vision or nausea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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CLARITHROMYCIN-500MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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CLARITHROMYCIN-500MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice may delay the gastrointestinal absorption of Clacin 500 Tablet. Avoid grapefruit juice while on treatment with Clacin 500 Tablet.

Diet & Lifestyle Advise

  • Probiotics and prebiotics can also help to reduce the side effects of antibiotics.
  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Eating grapefruit during antibiotic treatment can prevent the body from utilising Clacin 500 Tablet properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic.
  • Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of Clacin 500 Tablet.
  • Avoid the intake of alcoholic beverages, as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the medicine in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Clacin 500 Tablet Substitute

Substitutes safety advice
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Alcohol

Consult your doctor

Limited information is available. Keep your doctor informed if you drink alcohol.

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Pregnancy

Caution

Clacin 500 Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before taking Clacin 500 Tablet; your doctor will decide whether Clacin 500 Tablet can be taken by breastfeeding mothers or not.

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Driving

Consult your doctor

Not enough scientific data available, hence it is advised to consult your doctor.

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Liver

Caution

Clacin 500 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Clacin 500 Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Clacin 500 Tablet can be given safely to children above 6 months of age, with the dose to be adjusted and recommended by a child specialist only.

FAQs

Clacin 500 Tablet is used to treat bacterial infections, including chest infections, skin infections, and ear infections. Besides this, Clacin 500 Tablet is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori.

Clacin 500 Tablet contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Clacin 500 Tablet helps in the prevention of infections.

You should avoid taking iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking Clacin 500 Tablet. Avoid taking any other antibiotics containing Clacin 500 Tablet unless your doctor has prescribed you.

After taking antibiotics such as Clacin 500 Tablet, some people get thrush, a fungal infection. This is due to the fact that antibiotics kill the regular, harmless bacteria that serve to protect you from thrush.

Clacin 500 Tablet treats only bacterial infections. It will not work for viral infections (such as the common cold, flu).

No, Clacin 500 Tablet is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with a doctor's advice only.

Side effects are rare with Clacin 500 Tablet and do not usually last long. They will get better after a day or two. If any side effects persist, reach out to the doctor immediately.

No, Clacin 500 Tablet should not be stopped even if you feel better, as it is an antibiotic medication and completing the full course is very necessary; otherwise, the infection might reappear in a more severe form.

Country of origin

India

Manufacturer/Marketer address

8-G, 8th Floor, 560, Century Plaza, Anna Salai Teynampet Chennai - 600018, Tamil Nadu, India
Other Info - CLAC216

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Oct 22, 2025 | 12:42 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/product/6094/smpc#gref
  2. https://www.medicines.org.uk/emc/files/pil.6094.pdf
  3. https://www.nhs.uk/medicines/clarithromycin/
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