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  3. Clarksunate 120 Injection

Clarksunate 120 Injection, Pack of 1 Injection
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Clarksunate 120 Injection is used to treat malaria. It contains Artesunate which works by forming harmful chemicals within the malarial parasite and killing the parasites. In some cases, this medicine may cause side effects such as dizziness, headache, weakness, and loss of appetite. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

ARTESUNATE-120MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Clarksunate 120 Injection

Clarksunate 120 Injection belongs to the class of 'anti-malarial drugs', primarily used to treat malaria. Malaria is a disease caused by a plasmodium parasite, transmitted by the bite of infected Anopheles mosquitoes. When an infected mosquito bites a healthy person, it transmits the 'Plasmodium parasite' into the bloodstream, which affects the red blood cells and liver cells. Malaria symptoms usually start 10 days to 4 weeks after the infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhea, anemia, muscle pain, convulsions, coma, and bloody stools.

Clarksunate 120 Injection contains ‘Artesunate’. This Clarksunate 120 Injection is antimalarial medicine that interferes with the plasmodium parasite's growth in the red blood cells of the human body. Clarksunate 120 Injection is used to treat malaria caused by a parasite called 'Plasmodium falciparum,' another plasmodium species.  It works by forming harmful chemicals within the malarial parasite, therefore killing the parasites.

Clarksunate 120 Injection will be administered by a healthcare professional; do not self-administer. You may experience dizziness, headache, weakness, and loss of appetite (not feeling hungry). Most of these side effects of Clarksunate 120 Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before using Clarksunate 120 Injection, inform your doctor if you recently used any prescription and non-prescription medications, including other anti-malarial or antibiotic drugs. Let your doctor know if you are allergic to Clarksunate 120 Injection or its components. Inform your doctor if you have any liver or kidney problems. It is essential to let your doctor know if you are pregnant, planning to conceive, or are a breastfeeding mother. Clarksunate 120 Injection causes drowsiness and dizziness it is advisable to avoid driving unless you are alert.

Uses of Clarksunate 120 Injection

Treatment of Malaria

Directions for Use

• Your doctor will determine the dosage and timing of Clarksunate 120 Injection based on your health condition and response to treatment. • Clarksunate 120 Injection will be administered intravenously (through the vein) by a healthcare professional in a medical setting.• Do not self-administer it.

Medicinal Benefits

Clarksunate 120 Injection contains ‘Artesunate’. This Clarksunate 120 Injection is antimalarial medicine that interferes with the plasmodium parasite's growth in the red blood cells of the human body. It is used to treat cerebral malaria and all kind of severe malaria. The antimalarial effect of Clarksunate 120 Injection is commonly identified as generally safe, highly efficient and well-tolerated. Clarksunate 120 Injection is used to treat malaria caused by a parasite called 'Plasmodium falciparum,' other plasmodium species.  It works by forming harmful chemicals within the malarial parasite, therefore killing the parasites.

How Clarksunate 120 Injection Works

Clarksunate 120 Injection contains ‘Artesunate’. This Clarksunate 120 Injection is antimalarial medicine that interferes with the plasmodium parasite's growth in the red blood cells of the human body. Clarksunate 120 Injection is used to treat malaria caused by a parasite called 'Plasmodium falciparum,' another plasmodium species.  It works by forming harmful chemicals within the malarial parasite, therefore killing the parasites.

Storage

Keep this medicine out of the sight and reach of children.
Side effects of Clarksunate 120 Injection
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • High levels of bilirubin in blood leads to yellow discolouration of skin and eyes which is a significant liver issue that needs immediate medical attention.
  • Eating a balanced diet can help manage such side effects and must be taken as a dietician suggests.
  • Exercise regularly to maintain a good metabolism in your body.
  • Avoid alcohol consumption as it can affect liver functioning and worsen if there is a yellow discolouration of the skin and eyes.
  • Prevent toxins from chemicals that can be touched and inhaled. Ensure to manage your medications carefully.
  • Changes in kidney function need immediate medical attention.
  • Always monitor your blood pressure and inform your healthcare team if there are any sudden changes.
  • Take medicines as prescribed and eat a balanced diet suggested by your dietician for healthy kidney function.
  • Physical activity and exercise must be included in your daily routine to have proper kidney functioning and to maintain a healthy weight.
  • Get enough sleep to reduce the stress levels that have a direct impact on your kidney functioning.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Clarksunate 120 Injection

Since Clarksunate 120 Injection is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

Inform your doctor if you have any allergic reactions to Clarksunate 120 Injection or its components. Brief your medical history to the doctor if you have any liver or kidney problems, or heart disease. Blood problems may occur after you receive treatment with this Clarksunate 120 Injection. Inform your doctor immediately if you or your child have pain in the leg, back, or stomach, chills, bleeding gums, difficulty breathing, dark urine, general body swelling, fever, loss of appetite (feeling not hungry), headache, nosebleeds, nausea, or vomiting, sore throat, pale skin, unusual tiredness or weakness, or yellow skin or eyes. Inform your doctor immediately if you or your child have chest tightness, blurred vision, cough, confusion, faintness, dizziness, or lightheadedness. When getting up unexpectedly from a sitting or lying position, skin rash, redness of the skin, itching, sweating, swelling of your face, hands, or mouth, trouble breathing or swallowing, or unusual weakness or tiredness after you receive this Clarksunate 120 Injection. It is essential to let your doctor know if you are pregnant, planning to conceive, or are a breastfeeding mother. Clarksunate 120 Injection causes drowsiness and dizziness it is advisable to avoid driving unless you are alert.

Drug-Drug Interactions

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ArtesunateCabozantinib
Severe
ArtesunateEluxadoline
Severe

Drug-Drug Interactions

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ArtesunateCabozantinib
Severe
How does the drug interact with Clarksunate 120 Injection:
Taking Clarksunate 120 Injection with Cabozantinib may increase blood levels and effects of Clarksunate 120 Injection and increase the risk of side effects.

How to manage the interaction:
Although taking Clarksunate 120 Injection with cabozantinib together can result in an interaction, they can be taken if a doctor has prescribed it. Do not discontinue any medication without consulting a doctor.
ArtesunateEluxadoline
Severe
How does the drug interact with Clarksunate 120 Injection:
Taking Clarksunate 120 Injection with Eluxadoline may significantly increase the blood levels of eluxadoline. This may increase the risk and/or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Clarksunate 120 Injection and Eluxadoline, you can take these medicines together if prescribed by a doctor. However, if you experience persistent nausea, vomiting, drowsiness, constipation, stomach tenderness, and upper stomach pain, especially that which worsens after eating or radiates to the back or shoulders, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
ArtesunateAtazanavir
Moderate
How does the drug interact with Clarksunate 120 Injection:
Atazanavir may increase blood levels of Clarksunate 120 Injection and increase the risk of side effects such as liver damage, kidney failure, excess bilirubin in the blood, low red blood cell/platelet count and high white blood cell count.

How to manage the interaction:
If you are supposed to take Clarksunate 120 Injection and Atazanavir together, your doctor may adjust the dose or monitor more frequently to safely use both medications.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take nutritious food, including fresh fruits and vegetables that help in recovering from malarial fever.
  • During malarial fever, the patient may experience appetite loss. In such cases, drink glucose water, fresh fruit juices, and coconut water.
  • Include high-fiber foods like green leafy vegetables and fruits to aid digestion.
  • Take proper rest to help your body relax and heal faster.
  • Avoid or limit the intake of alcohol and caffeine.

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS

Clarksunate 120 Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid alcohol while using Clarksunate 120 Injection since it can worsen your side effects.

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Pregnancy

Unsafe

Clarksunate 120 Injection is not safe during pregnancy as it causes severe side effects to both mother and unborn baby.

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Breast Feeding

Caution

Clarksunate 120 Injection is present in breast milk but may not be expected to cause any side effects in the new-born baby especially more than 2 months. Please use only in the condition if your doctor is prescribed.

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Driving

Caution

Clarksunate 120 Injection may make you feel sleepy, dizzy, or generally weak. In such cases, do not drive or operate machinery.

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Liver

Caution

Close monitoring of patients with liver diseases while being treated with Clarksunate 120 Injection is required. Let your doctor know if you have any history of liver diseases before using Clarksunate 120 Injection. No specific dose adjustments are needed.

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Kidney

Caution

Therapy with Clarksunate 120 Injection is to be cautiously administered in patients with renal impairment. Let your doctor know if you have any history of kidney diseases before using Clarksunate 120 Injection. No specific dose adjustments are needed.

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Children

Safe if prescribed

Clarksunate 120 Injection is safely given to the children 6 months or older.

Have a query?

FAQs

Clarksunate 120 Injection is used to treat malaria.

Clarksunate 120 Injection is antimalarial medicine that interferes with the plasmodium parasite's growth in the red blood cells of the human body. Clarksunate 120 Injection is used to treat malaria caused by a parasite called "Plasmodium falciparum," other plasmodium species. It works by forming harmful chemicals within the malarial parasite, therefore killing the parasites.

Use of Clarksunate 120 Injection should be prevented in patients who are allergic to Clarksunate 120 Injection or any of its components. Though, if you are not aware of any allergy or if you are using Clarksunate 120 Injection for the first time, inform your doctor.

Before starting Clarksunate 120 Injection, inform your doctor if you have any other health illnesses like a kidney- or heart-related complications. This is because some medical conditions may affect your treatment and you may even require dose adjustments. Also, inform your doctor about all the other medicines you are taking as they may affect, or be affected by, this Clarksunate 120 Injection. Talk to your doctor if you are pregnant, planning to become pregnant or breastfeeding.

If you miss a dose of Clarksunate 120 Injection, take it as soon as you remember. Although, if it is approximately time for your next dose, skip the missed dose and take the next dose in the recommended time. Do not double the dose to make up for the missed one as this may enhance the probabilities of developing side effects.

Store Clarksunate 120 Injection between 10°C to 30°C according to the instructions on the leaflet and away from direct sunlight.

No, finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.

Yes, Clarksunate 120 Injection is effective against quinine-resistant malaria, especially severe Plasmodium falciparum infections.

Clarksunate 120 Injection will be administered intravenously (IV) by your doctor. Do not self-administer.

No, Clarksunate 120 Injection is primarily effective in treating severe malaria caused by Plasmodium falciparum. Clarksunate 120 Injection may not be effective for all types or stages of malaria, such as the dormant liver stages of plasmodium vivax. Always, consult a doctor for proper diagnosis and treatment.

Clarksunate 120 Injection is safe when used as prescribed by your doctor in the recommended dosage and duration. Follow your doctor's instructions and consult them if you have any concerns.

No, Clarksunate 120 Injection should only be administered by a healthcare professional to ensure accurate dosing and safe usage. Do not self-administer.

Yes, Clarksunate 120 Injection may cause side effects such as headache, dizziness, weakness, and loss of appetite. However, please contact a doctor if these continue for longer durations.

Pregnant women may use Clarksunate 120 Injection only if prescribed by a doctor, as untreated malaria poses severe risks to both mother and baby. Therefore, always inform your doctor if you are pregnant before taking Clarksunate 120 Injection.

Clarksunate 120 Injection can be used while breastfeeding if prescribed by your doctor. Artesunate passes into breast milk in small amounts but is unlikely to harm a newborn, especially those older than 2 months. However, it does not protect the child from malaria. Always follow your doctor’s advice regarding Clarksunate 120 Injection use during breastfeeding.

If you have kidney or liver disease, inform your doctor before using Clarksunate 120 Injection. Although dose adjustments are generally unnecessary, careful monitoring is essential during treatment. Therefore, always contact a doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

SCO-1 , SS Brother Complex 2nd Floor , Sai Road – Baddi 173205
Other Info - CL96160

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:47 AM IST

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Reference

  1. https://www.drugs.com/drug-interactions/artesunate.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/213036s000lbl.pdf
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