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  3. Clavspark 500mg/125mg Tablet

Clavspark 500mg/125mg Tablet, Pack of 1 Tablet
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Clavspark 500mg/125mg Tablet is used to treat bacterial infections, including ear, sinus, respiratory tract, urinary tract, skin, soft tissue, dental, joint and bone infections. It works by killing the infection-causing bacteria. In some cases, this medicine may cause side effects such as vomiting, nausea, and diarrhoea. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

AMOXYCILLIN-500MG + CLAVULANIC ACID-125MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Clavspark 500mg/125mg Tablet

Clavspark 500mg/125mg Tablet is used to treat bacterial infections in the body that affect the skin, soft tissues, lungs, ears, urinary tract, and nasal sinuses. It should be mentioned that viral infections like the flu and the common cold are not treated by this medication.

Clavspark 500mg/125mg Tablet consists of Amoxycillin and Clavulanic acid. This medicine works by destroying the outer protein layer, thereby killing the bacteria (bactericidal action). As a result, it helps treat infection and reduce the further spread of infection. Clavspark 500mg/125mg Tablet does not work against infections caused by viruses, including colds and flu.

Not everyone who is taking Clavspark 500mg/125mg Tablet will get these side effects. The common side effects of Clavspark 500mg/125mg Tablet include vomiting, nausea, and diarrhoea. Everyone may not experience the above side effects. In case of any discomfort, speak with a doctor.

You can take Clavspark 500mg/125mg Tablet with food to avoid any stomach upset. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your medicine based on your medical condition. It is always important to complete your treatment course for better results.

Before starting Clavspark 500mg/125mg Tablet, please inform your doctor if you have any allergy (against any antibiotic) or any other components. Do not take Clavspark 500mg/125mg Tablet on your own as it may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections. Clavspark 500mg/125mg Tablet is safe for children if prescribed by a doctor; the dose and duration may vary depending on the child’s weight and the severity of the infection. Inform your doctor if you are pregnant or breadfeeding before taking Clavspark 500mg/125mg Tablet.

Uses of Clavspark 500mg/125mg Tablet

Clavspark 500mg/125mg Tablet is used to treat Bacterial Infections. The detailed uses of Clavspark 500mg/125mg Tablet are as follows:
•Bacterial Infections: Clavspark 500mg/125mg Tablet helps treat bacterial illnesses, including pneumonia and bronchitis. The composition of Clavspark 500mg/125mg Tablet improves efficacy against resistant microorganisms.
•Sinusitis: Clavspark 500mg/125mg Tablet treats bacterial sinus infections by lowering inflammation and cleaning them.
•Urinary Tract Infections (UTIs): Clavspark 500mg/125mg Tablet treats urinary tract infections caused by susceptible bacteria and provides broad-spectrum protection.
•Skin and Soft Tissue Infection: Clavspark 500mg/125mg Tablet is also prescribed for treating skin and soft tissue infections, such as cellulitis and bite wounds, by its antibacterial effects to speed up the healing process.
•Otitis Media: Clavspark 500mg/125mg Tablet helps to treat middle ear infections.
•Pneumonia: Clavspark 500mg/125mg Tablet is also involved in treating pneumonia by efficiently fighting against the microorganisms that cause the condition.

Directions for Use

• Clavspark 500mg/125mg Tablet can be taken with food to avoid stomach upset. • It is usually taken every 8-12 hours or as prescribed by your doctor. • Swallow Clavspark 500mg/125mg Tablet as a whole with a glass of water. • Do not crush, chew, or break it.

Medicinal Benefits

  • Clavspark 500mg/125mg Tablet is a broad-spectrum antibiotic that covers a very wide range of bacterial infections.
  • Clavspark 500mg/125mg Tablet has Clavulanic acid, which protects amoxycillin from getting destroyed by the bacterial enzyme, thus increasing its efficacy.
  • Clavspark 500mg/125mg Tablet helps overcome antibiotic resistance in bacteria that is caused by the enzyme beta-lactamase.
  • Clavspark 500mg/125mg Tablet is an effective medicine used in multiple infections like ear infections (acute otitis media), bronchitis, pneumonia, urinary tract infections, skin infections, etc.

How Clavspark 500mg/125mg Tablet Works

Clavspark 500mg/125mg Tablet consists of two medicines: Amoxycillin and Clavulanic acid. Amoxycillin acts by destroying the outer protein layer, thereby killing the bacteria (bactericidal action). Clavulanic acid inhibits the enzyme beta-lactamase, which prevents bacteria from destroying the efficacy of amoxycillin. As a result, the action of Clavulanic acid allows Amoxycillin to work better and kill the bacteria. Clavspark 500mg/125mg Tablet does not work against infections caused by viruses, including colds and flu.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Clavspark 500mg/125mg Tablet

Take Clavspark 500mg/125mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms may include nausea, vomiting, diarrhoea, stomach pain, drowsiness, skin rash, hyperactivity, and decreased urination. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Clavspark 500mg/125mg Tablet if you have an allergy to Clavspark 500mg/125mg Tablet, penicillin or cephalosporin class of antibiotics. Also, after taking Clavspark 500mg/125mg Tablet, if you have an allergic symptom, including rash, swelling of the face/lips/throat, difficulty breathing, or chest tightness, immediately contact your doctor. People with liver diseases or jaundice (yellowing of skin/eye) should not take Clavspark 500mg/125mg Tablet, as it can severely affect the liver. Inform your doctor if you have any kidney or heart disease before taking Clavspark 500mg/125mg Tablet.

Consult your doctor before taking Clavspark 500mg/125mg Tablet if you are pregnant or breastfeeding. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects. The dose of Clavspark 500mg/125mg Tablet can vary depending on your condition and the severity of the infection. Also, it is recommended to complete the course of medicine even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance).

Store Clavspark 500mg/125mg Tablet at room temperature. You are advised not to chew, crush or break the medicine. Keep the medicine out of reach of children. Please do not take more than the recommended dose of medicine, as it can cause undesirable effects. It is always important to check for the expiry of the medicine. Discard the medicine if it reaches the expiry date. If you experience any chest pain, call your doctor immediately.

Drug-Drug Interactions

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AmoxicillinBCG vaccine
Severe
AmoxicillinDoxycycline
Severe

Drug-Drug Interactions

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AmoxicillinBCG vaccine
Severe
How does the drug interact with Clavspark 500mg/125mg Tablet:
Co-administration of BCG vaccine with Clavspark 500mg/125mg Tablet may reduce the effect of BCG vaccine.

How to manage the interaction:
If you are about to receive BCG vaccine, inform the doctor that you are taking Clavspark 500mg/125mg Tablet. Do not discontinue the medication without consulting a doctor.
AmoxicillinDoxycycline
Severe
How does the drug interact with Clavspark 500mg/125mg Tablet:
Co-administration of Clavspark 500mg/125mg Tablet with doxycycline may reduce the therapeutic effect of Clavspark 500mg/125mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Clavspark 500mg/125mg Tablet and Doxycycline, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
AmoxicillinZalcitabine
Severe
How does the drug interact with Clavspark 500mg/125mg Tablet:
Co-administration of Clavspark 500mg/125mg Tablet and Zalcitabine can be decreased when combined with Clavspark 500mg/125mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Zalcitabine and Clavspark 500mg/125mg Tablet, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AmoxicillinMethotrexate
Severe
How does the drug interact with Clavspark 500mg/125mg Tablet:
Co-administration of methotrexate with Clavspark 500mg/125mg Tablet can increase the levels and side effects of methotrexate.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Clavspark 500mg/125mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as tiredness, dizziness, fainting, unusual bleeding or bruising, chills, fever, sore throat, body pains. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
AmoxicillinCholera, live attenuated
Severe
How does the drug interact with Clavspark 500mg/125mg Tablet:
Co-administration of Clavspark 500mg/125mg Tablet and Cholera, live attenuated may reduce the activity of the vaccine.

How to manage the interaction:
If you are currently being treated with Clavspark 500mg/125mg Tablet or have been treated within the last 14 days, talk to your doctor before receiving cholera vaccine, live. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics.
  • Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Probiotics should be taken after taking a full course of Clavspark 500mg/125mg Tablet in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea.
  • Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.
  • Avoid alcoholic beverages with Clavspark 500mg/125mg Tablet as they can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Clavspark 500mg/125mg Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- INFECTIVES

Clavspark 500mg/125mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid consumption of alcohol during the treatment with Clavspark 500mg/125mg Tablet as it may worsen the side effects like dizziness.

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Pregnancy

Consult your doctor

If you are pregnant, consult your doctor before taking Clavspark 500mg/125mg Tablet. Your doctor will prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

This medication passes into breast milk. If you are a nursing mother, consult your doctor before taking Clavspark 500mg/125mg Tablet. Your doctor will prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Clavspark 500mg/125mg Tablet may cause dizziness in some people, so it may affect your ability to drive. Avoid driving or operating machines until you are alert after taking Clavspark 500mg/125mg Tablet.

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Liver

Caution

Clavspark 500mg/125mg Tablet to be taken with caution if you have a history of liver conditions. Your doctor may adjust the dose if necessary based on your condition.

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Kidney

Caution

Clavspark 500mg/125mg Tablet to be taken with caution, especially if you have a history of kidney conditions. Your doctor may adjust the dose if necessary based on your condition.

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Children

Consult your doctor

Please consult the doctor. Your child's doctor will decide the dosage of this medicine depending on the weight and the severity of the infection.

Have a query?

FAQs

Clavspark 500mg/125mg Tablet is used to prevent middle ear and sinus infections, throat or lung respiratory tract infections, urinary tract infections, skin infections, soft tissue infections, dental infections, and joint and bone infections.

Clavspark 500mg/125mg Tablet contains Amoxycillin and Clavulanic acid. Amoxycillin works by preventing the formation of bacterial cell covering, which is necessary for the survival of the bacteria. Thus it kills the bacteria. Clavulanic acid works by decreasing bacterial resistance and enhancing the activity of amoxycillin against the bacteria. Together, Clavspark 500mg/125mg Tablet helps in treating bacterial infections.

Clavspark 500mg/125mg Tablet is known to cause stomach upset, indigestion, nausea, and diarrhea. To avoid these side effects, please take Clavspark 500mg/125mg Tablet with a meal. Also, Clavspark 500mg/125mg Tablet should be taken at evenly spaced intervals to avoid any unpleasant side effects and for best results.

Generally, the penicillin group of antibiotics is not advised to be taken with methotrexate, which is used for conditions like psoriasis, rheumatoid arthritis, etc. They may cause unpleasant side effects when taken together. However, Clavspark 500mg/125mg Tablet is relatively safer to take with methotrexate, but only if prescribed by the doctor. It is best to discuss with your doctor about using the two medicines together, who may weigh the pros and cons and decide what is best for you.

Usually, Clavspark 500mg/125mg Tablet does not cause jaundice. But sometimes, it can cause jaundice in elderly people who have been taking the medication for a prolonged time. Please consult your doctor immediately if you notice any yellowing of the skin/eyes.

Clavspark 500mg/125mg Tablet does not treat a viral infection like the flu or a common cold. It is best to consult the doctor to know if you need Clavspark 500mg/125mg Tablet for your condition.

Yes, after taking Clavspark 500mg/125mg Tablet, you may have diarrhea. So, drink plenty of fluids and take probiotics to prevent excessive loss of fluids from the body (dehydration). Do not take anti-diarrhea medicine on your own; consult your doctor if the condition worsens.

Clavspark 500mg/125mg Tablet is not known to reduce the efficacy of birth control pills and emergency contraceptive pills. However, if you develop diarrhea or vomiting due to Clavspark 500mg/125mg Tablet, you are recommended to use other contraceptive methods such as condoms along with contraceptives to avoid unwanted pregnancies. Discuss with your doctor if you have any concerns regarding using Clavspark 500mg/125mg Tablet and your birth control pills.

Clavspark 500mg/125mg Tablet may show its effect 1.5 hours after taking the medicine. However, clinical improvement may be noticed after 48 hours.

Clavspark 500mg/125mg Tablet should be taken for the duration prescribed by the doctor based on your condition. Usually, it is taken every 8-12 hours.

Clavspark 500mg/125mg Tablet contains amoxicillin and clavulanic acid used to treat bacterial infections of the ear, sinus, respiratory tract, urinary tract, skin, soft tissue, dental, joints and bones.

Yes, Clavspark 500mg/125mg Tablet is safe to use if prescribed by the doctor.

Clavspark 500mg/125mg Tablet should not be used if you are allergic to any of its components or if you had jaundice or liver problems when taking an antibiotic.

Do not exceed the recommended dose of Clavspark 500mg/125mg Tablet as it might cause stomach upset or convulsions. Take Clavspark 500mg/125mg Tablet only as advised by the doctor.

Store Clavspark 500mg/125mg Tablet at room temperature (below 25°C). Keep it out of sight and reach of children. To help protect the environment, avoid throwing away any medicines via wastewater or household waste. Ask your pharmacist regarding the disposal of medicines.

To treat your infection effectively, continue taking Clavspark 500mg/125mg Tablet for the prescribed duration even if your symptoms are relieved.

Clavspark 500mg/125mg Tablet may cause an allergic reaction like skin rash, vasculitis (inflammation of blood vessels), angioedema (swelling), and difficulty breathing. Consult the doctor if you experience these symptoms.

No, Clavspark 500mg/125mg Tablet does not cause drowsiness. Sometimes, it might cause dizziness as an uncommon side effect. Drive or operate machinery only if you are alert.

Clavspark 500mg/125mg Tablet should be swallowed as a whole with water. Take the medicine with a meal.

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking Clavspark 500mg/125mg Tablet.

The common side effects of Clavspark 500mg/125mg Tablet include vomiting, nausea, and diarrhoea. In case of any discomfort, speak with a doctor.

Clavspark 500mg/125mg Tablet should be taken only if prescribed by the doctor. It should not be taken by people who are allergic to amoxicillin, clavulanic acid, penicillin or any of the other ingredients of this medicine, ever had a severe allergic reaction (skin rash or swelling of the face or throat) to any other antibiotic or liver problems/jaundice (yellowing of the skin) when taking an antibiotic.

Let the doctor know if you are taking gout medicine (allopurinol, probenecid), blood thinners (warfarin), anticancer, or anti-arthritis drugs (methotrexate), and drugs to prevent organ transplant (mycophenolate mofetil).

Seek immediate medical attention if you have overdosed on Clavspark 500mg/125mg Tablet. Taking too much of Clavspark 500mg/125mg Tablet may cause upset stomach (nausea, vomiting or diarrhoea) or convulsions.

Country of origin

India
Other Info - CL79897

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 14, 2025 | 12:58 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.9127.pdf
  2. https://gskpro.com/en-mt/products/augmentin/indication/
  3. https://www.nhs.uk/medicines/co-amoxiclav/
  4. https://www.drugs.com/augmentin.html
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