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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Clexane 40mg Injection is used to prevent or treat blood clots caused by medical conditions, such as unstable angina, after an operation or long periods of bed rest due to illness, after a heart attack, and the formation of blood clots in the dialysis machine tubes. It contains Enoxaparin, which prevents existing blood clots from growing larger, allowing your body to break them down and prevent them from harming you. Also, it inhibits the formation of new blood clots in your blood. It may cause side effects such as increased liver enzymes, skin rash (hives,urticaria), itchy red skin, bruising or pain at the injection site, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

ENOXAPARIN-40MG

Manufacturer/Marketer :

Sanofi India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Clexane 40mg Injection

Clexane 40mg Injection is used to prevent or treat blood clots caused by medical conditions, such as unstable angina, after an operation or long periods of bed rest due to illness, after a heart attack, and the formation of blood clots in the dialysis machine tubes. A blood clot is a mass of blood that forms when platelets, proteins, and cells in the blood stick together. A blood clot can occur in any body part, leading to a heart attack, stroke, and organ damage (even coma or death).

Clexane 40mg Injection contains Enoxaparin, which is a low molecular weight heparin that works by preventing existing blood clots from growing larger, allowing your body to break them down and prevent them from harming you. On the other hand, it inhibits the formation of new blood clots in your blood.

Clexane 40mg Injection will be administered by a healthcare professional; do not self-administer. Side effects of Clexane 40mg Injection include increased liver enzymes, skin rash (hives, urticaria), itchy red skin, bruising or pain at the injection site, and headache. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, report to your doctor immediately. 

If you are known to be allergic to Clexane 40mg Injection or any other medicines, inform your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before receiving the Clexane 40mg Injection . Also, disclose to your doctor if you have any pre-existing medical conditions like a stomach ulcer, recent surgery of the brain or eyes or spine, recent bleeding stroke, diabetes, high blood pressure, or recent onset of stroke or kidney or liver disorders. Also, let your doctor know if you are underweight or overweight or if you have high levels of potassium in your blood.

Uses of Clexane 40mg Injection

Treatment and prevention of blood clots

Directions for Use

Clexane 40mg Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Clexane 40mg Injection contains Enoxaparin, which is a low molecular weight heparin (LMWH) that helps to treat harmful blood clots due to medical conditions, including unstable angina, after an operation or long periods of bed rest due to illness, after a heart attack, and blood clots forming in the tubes of your dialysis machine. Clexane 40mg Injection works by stopping existing blood clots from getting any bigger; this helps your body break them down and prevents them from causing you harm. On the other hand, it stops new blood clots from forming in your blood.

How Clexane 40mg Injection Works

Clexane 40mg Injection contains Enoxaparin, which is a low molecular weight heparin that works by preventing existing blood clots from growing larger, allowing your body to break them down and prevent them from harming you. On the other hand, it inhibits the formation of new blood clots in your blood.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Clexane 40mg Injection

  • Bleeding
  • Increases in liver enzymes
  • Bruise more easily than usual
  • Pink patches on your skin 
  • Skin rash (hives, urticaria)
  • Itchy red skin
  • Bruising or pain at the injection site
  • Decreased red blood cell count
  • High platelet counts in the blood
  • Headache

What if I have taken an overdose of Clexane 40mg Injection

The overdose of Clexane 40mg Injection is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with Clexane 40mg Injection , please inform your doctor immediately.

Drug Warnings

Patients should inform the doctor if they are on active treatment with this Clexane 40mg Injection before any surgery is scheduled. If you are known to be allergic to Clexane 40mg Injection or any other medicines, inform your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using the Clexane 40mg Injection . Before using this Clexane 40mg Injection , disclose to your doctor if you have any pre-existing medical conditions like stomach ulcer, recent surgery of the brain or eyes or spine, recent bleeding stroke, diabetes, high blood pressure, or recent onset of stroke or kidney or liver disorders, And also let your doctor know if you are underweight or overweight or if you have high levels of potassium in your blood.

Drug-Drug Interactions

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EnoxaparinDefibrotide
Critical
EnoxaparinMifepristone
Critical

Drug-Drug Interactions

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EnoxaparinDefibrotide
Critical
How does the drug interact with Clexane 40mg Injection 0.4 ml:
Combining Defibrotide with Clexane 40mg Injection 0.4 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Clexane 40mg Injection 0.4 ml with Defibrotide is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EnoxaparinMifepristone
Critical
How does the drug interact with Clexane 40mg Injection 0.4 ml:
Combining Mifepristone with Clexane 40mg Injection 0.4 ml can increase the risk or severity of side effects of vaginal bleeding.

How to manage the interaction:
Taking Clexane 40mg Injection 0.4 ml with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience prolonged, excessive bleeding, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EnoxaparinDextran
Severe
How does the drug interact with Clexane 40mg Injection 0.4 ml:
Combining Clexane 40mg Injection 0.4 ml with Dextran can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Dextran and Clexane 40mg Injection 0.4 ml, but it can be taken if prescribed by a doctor. If you notice any symptoms like bleeding, bruising, dizziness, black or tarry stools, severe headache, weakness, or vomiting contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EnoxaparinTinzaparin
Severe
How does the drug interact with Clexane 40mg Injection 0.4 ml:
Combining Clexane 40mg Injection 0.4 ml with Tinzaparin can increase the risk of bleeding.

How to manage the interaction:
Although taking Clexane 40mg Injection 0.4 ml and Tinzaparin together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these symptoms like back pain, bleeding, bruises, dizziness, lightheaded, dark or black stools, a severe headache, weakness, or vomiting it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
EnoxaparinTenecteplase
Severe
How does the drug interact with Clexane 40mg Injection 0.4 ml:
Combining Tenecteplase with Clexane 40mg Injection 0.4 ml can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Tenecteplase with Clexane 40mg Injection 0.4 ml can result in an interaction, but it can be taken if your doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Using more than one of these medications can increase the risk of bleeding even more, but it may not give you much extra protection. Do not discontinue any medications without consulting a doctor.
EnoxaparinApixaban
Severe
How does the drug interact with Clexane 40mg Injection 0.4 ml:
Coadministration of Apixaban and Clexane 40mg Injection 0.4 ml co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Clexane 40mg Injection 0.4 ml and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
EnoxaparinPanobinostat
Severe
How does the drug interact with Clexane 40mg Injection 0.4 ml:
Coadministration of Clexane 40mg Injection 0.4 ml and Panobinostat can increase the risk or severity of bleeding complications.

How to manage the interaction:
Although taking Clexane 40mg Injection 0.4 ml and Panobinostat together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any symptoms like bleeding, bruising, dizziness, severe headache red or black stools, vomiting, or weakness it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
EnoxaparinIbrutinib
Severe
How does the drug interact with Clexane 40mg Injection 0.4 ml:
Co-administration of Ibrutinib with Clexane 40mg Injection 0.4 ml can increase the risk or severity of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Ibrutinib and Clexane 40mg Injection 0.4 ml, but it can be taken if prescribed by a doctor. If you have any symptoms like unusual bleeding or bruising, dizziness, black or bloody stools, coughing up blood, vomiting blood, severe headache, or weakness, contact a doctor immediately. Do not stop using any medications without a doctor's advice.
EnoxaparinPrasugrel
Severe
How does the drug interact with Clexane 40mg Injection 0.4 ml:
Co-administration of Prasugrel with Clexane 40mg Injection 0.4 ml can increase the risk or severity of bleeding.

How to manage the interaction:
Although there is a possible interaction between Prasugrel and Clexane 40mg Injection 0.4 ml, you can take them if advised by a doctor. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor. Do not stop using any medications without a doctor's advice.
EnoxaparinDalteparin
Severe
How does the drug interact with Clexane 40mg Injection 0.4 ml:
Combining Clexane 40mg Injection 0.4 ml with Dalteparin can increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin and Clexane 40mg Injection 0.4 ml together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any symptoms like bleeding, severe headaches, weakness, or vomiting, it's important to consult a doctor immediately. Do not discontinue any medications without first consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A low cholesterol diet and a regular exercise regime complement treatment with Clexane 40mg Injection effectively.
  • As a precautionary measure, you are recommended not to consume alcohol, or junk food items from outside, stick to a freshly prepared home-cooked meal and rest properly for a speedy recovery.
  • And also, trying to replace most of your saturated fats with unsaturated fats can reduce total cholesterol and LDL in a short time.
  • Foods like avocados, olive oil, fatty fish, and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Option for foods high in vitamin K (liver, leafy green vegetables, or vegetable oils) as Clexane 40mg Injection may lower Vitamin K in your body.
  • Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.
  • Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with Clexane 40mg Injection and lead to unwanted side effects. Hence try to avoid these juices while taking Clexane 40mg Injection .

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Clexane 40mg Injection Substitute

Substitutes safety advice
  • Corparin 40 Injection 1's

    by AYUR

    423.00per tablet
  • Lmwx 40 Injection 0.4 ml

    by Others

    413.60per tablet
  • Loparin 40 mg Injection 0.4 ml

    by Others

    358.70per tablet
  • Enoxarin-40 Injection 0.4 ml

    by AYUR

    423.00per tablet
  • Parihep 40 mg Injection 0.4 ml

    by Others

    423.00per tablet
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Alcohol

Caution

Limit intake of alcohol as it may increase the risk of bleeding.

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Pregnancy

Caution

Clexane 40mg Injection is not recommended for use in pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Clexane 40mg Injection .

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Breast Feeding

Caution

Clexane 40mg Injection is not recommended for use in breastfeeding unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Clexane 40mg Injection .

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Driving

Safe if prescribed

It does not affect your ability to drive.

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Liver

Caution

If you have a history of liver diseases or pre-existing liver conditions, please inform your doctor before taking this Clexane 40mg Injection . Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

If you have a history of kidney diseases or pre-existing kidney conditions, please inform your doctor before taking this Clexane 40mg Injection . Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

It is not recommended for treatment in children under 18 years of age as safety and efficacy have not been established.

FAQs

Clexane 40mg Injection is used to prevent or treat blood clots caused by medical conditions, such as unstable angina, after an operation or long periods of bed rest due to illness, after a heart attack, and the formation of blood clots in the dialysis machine tubes.

Clexane 40mg Injection contains Enoxaparin, which is low molecular weight heparin or LMWH. Clexane 40mg Injection works by stopping existing blood clots from getting any bigger. This helps your body to break them down and prevents them from causing you harm. On the other hand, it stops new blood clots from forming in your blood.

Yes, this Clexane 40mg Injection is given based on your age and body weight. If you have low body weight, the chances of increased risk of bleeding are high, so mostly low doses are prescribed by your doctor. You may be monitored closely for signs of clot formation.

No, do not take this Clexane 40mg Injection if you have a stomach ulcer. Please inform your doctor about this condition before receiving it.

Yes, Clexane 40mg Injection may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, or unusual bleeding from the gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.

Increases in liver enzymes are the most common side effect with Clexane 40mg Injection . Regular lipid profile tests are recommended to avoid any additional complications.

Clexane 40mg Injection typically starts showing its effect within 1 to 2 hours and it remains in the body for about 12 hours.

No, Clexane 40mg Injection dosage should be given exactly as prescribed by the doctor.

Clexane 40mg Injection contains Enoxaparin as it active ingredient.

Clexane 40mg Injection is mostly prescribed for angina (chest pain), deep vein thrombosis (blood clot in veins) and as a post-surgery precautionary step.

Yes, there are many substitutes available in the market. However, please note that all these substitutes have the same composition and thus should be administered with the same set of precautions.

Clexane 40mg Injection will be administered by a doctor or nurse in the hospital or clinic. Do not self-administer.

Bleeding is one of the side effects of Clexane 40mg Injection in some individuals. If you experience any kind of unusual symptoms such as black tarry stool, unusual bleeding, etc., inform the doctor immediately.

The side effects of Clexane 40mg Injection include bleeding, increases in liver enzymes, bruise more easily than usual, pink patches on your skin, skin rash (hives, urticaria), itchy red skin, pain or bruising at the injection site and headache. If these side effects persist or worsen, please inform your doctor.

The dose and duration of Clexane 40mg Injection is prescribed by a doctor based on the underlying condition and the patient’s response to the treatment.

Clexane 40mg Injection is injected beneath the skin. Fix the medicine dose and make a fold by pinching the skin of your stomach between your finger and thumb. After cleansing the area, hold the syringe like a pencil and insert the full length of the needle into the skin fold. Inject Clexane 40mg Injection and discard the syringe as instructed by your doctor. Follow the instructions given by the doctor strictly. In case of any doubt or any reactions associated with the medicine, contact your doctor.

Tell your doctor if you have a heart valve fitted or have high blood pressure, gastric ulcer, kidney problems or diabetes. Also, let your doctor know if you ever had a reaction to heparin or had a recent stroke, spinal or brain surgery. The chances of complications and side effects increase in these conditions.

Store Clexane 40mg Injection below 25°C. Do not freeze. Keep it out of reach and sight of children.

Yes, Clexane 40mg Injection is used in the treatment of heart attack and chest pain once the patient has received the standard treatment. It is administered along with another blood thinner like aspirin. As it is a blood thinner, it prevents the blood from clotting and prevents any further episodes and complications.

Yes, you can push the air bubbles into the injection site. Removing the air bubbles causes loss of the medicine thereby changing the prescribed dose.

Country of origin

France

Manufacturer/Marketer address

CT Survey No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072.
Other Info - CLE0014

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Keep Refrigerated. Do not freeze.Prepaid payment required.

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