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Clopitorva 10 Capsule is used to prevent heart attack and stroke in the future. It lowers the raised level of cholesterol and fats (triglycerides) in our bodies. It contains Atorvastatin and Clopidogrel, which lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Also, it prevents a clot in the blood vessels. In some cases, it may cause side effects such as headaches, ankle swelling (oedema), slow heart rate, and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Clopitorva 10 Capsule

Clopitorva 10 Capsule is used in the prevention of heart attack, myocardial infarction (blockage of the blood to muscles of the heart), angina (chest pain), and stroke. A heart attack occurs when your coronary arteries (blood vessels supplying blood and oxygen to the heart) become blocked due to the buildup of fats (plaque), including cholesterol.

Clopitorva 10 Capsule is a combination of Atorvastatin and Clopidogrel. Atorvastatin blocks the ability of the body to produce bad cholesterol and improves the ability of the body to make good cholesterol. Clopidogrel works by decreasing the production of clots, which is harmful to the body.

Not everyone who is taking Clopitorva 10 Capsule will get these side effects. You may sometimes experience headaches, ankle swelling (oedema), slow heart rate, dizziness, and nausea. Most of these side effects of Clopitorva 10 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your physician if you are allergic to Clopitorva 10 Capsule . Before starting the dose of Clopitorva 10 Capsule , let your doctor know if you are sensitive to atorvastatin or clopidogrel or have any active liver disease (liver enzyme abnormalities), active bleeding issues (like peptic ulcer, brain haemorrhage), or muscle problems (myopathy or rhabdomyolysis), or if you are pregnant/breastfeeding. 

Uses of Clopitorva 10 Capsule

Clopitorva 10 Capsule is used in the treatment of hyperlipidemia (increased cholesterol) and the prevention of cardiovascular events. The detailed uses of Clopitorva 10 Capsule are as follows:

  • Treatment of Hyperlipidemia: Clopitorva 10 Capsule is used to treat hyperlipidemia by lowering cholesterol levels, particularly LDL (bad) cholesterol.
  • Prevention of Heart Attacks: Clopitorva 10 Capsule helps to prevent heart attacks by inhibiting platelet aggregation, reducing the risk of blood clots.
  • Stroke Prevention: Clopitorva 10 Capsule helps prevent strokes by reducing platelet aggregation, thereby decreasing the risk of clot formation in blood vessels.

Key Benefits

  • Atorvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body.
  • Clopitorva 10 Capsule helps lower the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL).
  • Clopidogrel is a blood thinner (anticoagulant) that collectively prevents clot formation in the blood vessels.
  • It reduces the risk of heart attack, stroke and heart-related chest pain (angina).

Directions for Use

  • Clopitorva 10 Capsule can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Clopitorva 10 Capsule as a whole with a glass of water.
  • Do not chew, crush or break it.

How Clopitorva 10 Capsule Works

Clopitorva 10 Capsule is composed of two medicines, namely: Atorvastatin and Clopidogrel. Atorvastatin is a lipid-lowering medication which blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents a clot in the blood vessels. Together Clopitorva 10 Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke and heart-related chest pain (angina).
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Alcohol

Unsafe

Clopitorva 10 Capsule should not be taken with alcohol as it may worsen your liver condition with increased secretion of liver enzymes like transaminase. Keep your doctor informed if you drink alcohol.

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Pregnancy

Unsafe

Clopitorva 10 Capsule contains atorvastatin, which is a pregnancy category X medicine. It may cause harm to both the pregnant mother and the fetus. Hence, it is not recommended for pregnant women and those who are planning a pregnancy. Your doctor might prescribe it only in an extreme case.

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Breast Feeding

Consult your doctor

Take Clopitorva 10 Capsule only when prescribed, as it is known to pass on in a limited quantity via breast milk to the child.

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Driving

Unsafe

Drive with caution, Clopitorva 10 Capsule usually causes blurry vision and may affect driving ability.

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Liver

Caution

Clopitorva 10 Capsule to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Clopitorva 10 Capsule to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Clopitorva 10 Capsule is not recommended for children below the age of 10 years. The safety and effectiveness of Clopitorva 10 Capsule have not been established in children due to limited testing of Clopitorva 10 Capsule on children by competent authorities worldwide.

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Heart

Safe if prescribed

Clopitorva 10 Capsule can be used in heart patients if prescribed by the physician to reduce the risk of heart attack and stroke. Please consult your physician if you have any concerns.

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Geriatrics

Consult your doctor

Clopitorva 10 Capsule should be used in elderly people only if prescribed by the physician.

What if I have taken an overdose of Clopitorva 10 Capsule

Do not take more than the prescribed dose of Clopitorva 10 Capsule as it may cause vomiting, breathing difficulty, gastrointestinal haemorrhage, and extreme physical weakness. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • A low-cholesterol diet along with a regular exercise regimen is found to complement treatment with Clopitorva 10 Capsule effectively.
  • Stick to a freshly prepared home-cooked meal and avoid processed, packaged foods that contain hidden sugar and extra calories.
  • Try to replace most of your saturated fats with unsaturated fats to reduce total cholesterol and LDL cholesterol (bad cholesterol) quickly.
  • Foods like avocados, olive oil, fatty fish and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Include a diet enriched in fats like fish oils, polyunsaturated oils, and omega-3 fatty acids, which are good for heart health.
  • Quit smoking and avoid excessive intake of alcohol.

Have a query?

How Soon It Starts Working

The time required for Clopitorva 10 Capsule to start to work: The time required for Clopitorva 10 Capsule to show its action is unknown. The time for which the effects of Clopitorva 10 Capsule last: The duration of action for Clopitorva 10 Capsule is unknown.

What if you forget to take Clopitorva 10 Capsule

If you miss a dose of Clopitorva 10 Capsule , take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not take a double dose to make up for the missed dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Tell your doctor if you are sensitive to Atorvastatin or clopidogrel, have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), are pregnant or planning to become pregnant or are breastfeeding.
  • The patient should inform the doctor that they are taking Clopitorva 10 Capsule before any surgery is scheduled or any new medicine is taken.
  • Atorvastatin present in Clopitorva 10 Capsule is a pregnancy category X drug, so it is contraindicated in pregnant women. It may cause harm to the foetus if administered to pregnant women.
  • The risk of muscle disease might increase if Clopitorva 10 Capsule is taken with an antibiotic (clarithromycin), anti-HIV drugs (ritonavir, lopinavir, darunavir, atazanavir, indinavir) and antifungal (itraconazole).
  • Coadministration with anticoagulants like warfarin may cause gastric bleeding and other bleeding problems. So, if you are using any blood-thinning agents, let your doctor know.
  • Clopitorva 10 Capsule contains atorvastatin, which can cause muscle problems like myopathy and rhabdomyolysis.
  • Patients with active liver disease should use the Clopitorva 10 Capsule with caution.
  • The safety and effectiveness of Clopitorva 10 Capsule have not been established, so its use should be avoided in paediatric patients or children younger than ten years of age.
  • Discontinuation of Clopitorva 10 Capsule may lead to cardiovascular events like heart attack, stroke and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of Clopitorva 10 Capsule .

Drug-Drug Interactions

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Drug-Drug Interactions: Clopitorva 10 Capsule interacts with antibiotics (e.g. clarithromycin), anti-HIV drugs (e.g. ritonavir, lopinavir, darunavir, atazanavir, indinavir), antifungal (e.g. itraconazole), blood thinners (e.g. warfarin, coumadin, heparin), anti-arthritis drug (e.g. colchicine), heart-related medicine (e.g. digoxin) and immune system affecting drug (e.g. cyclosporine).

Drug-Food Interactions: Alcoholic beverages and grapefruit or its juice intake should be avoided with Clopitorva 10 Capsule . It may interact with Clopitorva 10 Capsule to produce unpleasant side effects like muscle problems and bleeding disorder.

Drug-Disease Interactions: Caution should be exercised while using Clopitorva 10 Capsule in patients with active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), muscle problems or musculoskeletal problems (myopathy, rhabdomyolysis), asthma, and purpura (blood leakage under the skin).

Critical
Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Clopitorva 10 Capsule:
Taking Clopitorva 10 Capsule and Telaprevir can significantly increase the blood levels of atorvastatin that may increase the risk of side effects such as liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Clopitorva 10 Capsule and Telaprevir together is generally not recommended as it result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, fever, dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light colored stools, or yellowing of the skin or eyes, you should consult a doctor. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Clopitorva 10 Capsule:
Taking Mibefradil with Clopitorva 10 Capsule is not recommended.

How to manage the interaction:
Taking Mibefradil with Clopitorva 10 Capsule is not recommended as it may results in the interaction.
How does the drug interact with Clopitorva 10 Capsule:
Taking Clopitorva 10 Capsule with Posaconazole can increase the blood levels of atorvastatin. This can increase the risk of side effects.

How to manage the interaction:
Taking posaconazole with Clopitorva 10 Capsule is not recommended as it results in an interaction, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Clopitorva 10 Capsule:
Taking Clopitorva 10 Capsule together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Clopitorva 10 Capsule with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Clopitorva 10 Capsule:
When Selexipag and Clopitorva 10 Capsule are taken together, the body's ability to break down Selexipag may be reduced that may increase risk of side effects.

How to manage the interaction:
Taking Clopitorva 10 Capsule with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
How does the drug interact with Clopitorva 10 Capsule:
Taking Clopitorva 10 Capsule together with Fondaparinux can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Clopitorva 10 Capsule and Fondaparinux, but they can be taken together if prescribed by your doctor. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Clopitorva 10 Capsule:
Using Clopitorva 10 Capsule together with itraconazole may significantly increase the blood levels of atorvastatin that may increase the risk of side effects such as liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Coadministration of Clopitorva 10 Capsule along with itraconazole together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Clopitorva 10 Capsule:
The combination of Clopitorva 10 Capsule and letermovir may substantially elevate the blood levels of atorvastatin that may increase the risk of side effects such as liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Clopitorva 10 Capsule with letermovir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Clopitorva 10 Capsule:
Taking Clopitorva 10 Capsule with rifampicin can decrease the blood levels of atorvastatin, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Clopitorva 10 Capsule and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Clopitorva 10 Capsule:
Taking Clopitorva 10 Capsule with Defibrotide can increase the risk of bleeding.

How to manage the interaction:
Although taking Clopitorva 10 Capsule and Defibrotide together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult a doctor if you experience bleeding, complications, bruising, feeling dizzy or lightheaded, having black or tarry stools, experiencing a severe headache, feeling weak, or having bleeding or vomiting. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Therapeutic Class

[CARDIOVASCULAR AGENTS]

FAQs

Clopitorva 10 Capsule is used to treat Hyperlipidemia (Increased cholesterol), heart attack prevention, and stroke prevention.

Yes, Clopitorva 10 Capsule contains clopidogrel which prevents blood clotting. It works by preventing platelets (a type of blood cell) from sticking together and forming clots which in turn prevents the risk of heart attack and stroke.

Yes, taking Clopitorva 10 Capsule can increase the risk of bleeding as it contains aspirin and clopidogrel, which belong to a class of blood-thinning agents. So, please be very cautious while shaving, cutting fingernails or toenails, or using sharp objects to avoid any bleeding. Let your doctor know before undergoing any surgical procedure that you are taking Clopitorva 10 Capsule .

No. Clopitorva 10 Capsule contains Atorvastatin, which is a pregnancy category X medicine and can cause harm to both the pregnant mother and the unborn baby. Even if you are planning for pregnancy, tell your doctor that you are using Clopitorva 10 Capsule .

Yes, prolonged use of Clopitorva 10 Capsule may cause muscle diseases like myopathy and rhabdomyolysis. So if you feel any musculoskeletal pain after taking Clopitorva 10 Capsule consult your doctor about this issue.

Do not drink grapefruit juice while taking Clopitorva 10 Capsule . Grapefruit juice may increase the blood-thinning effect of your medicine.

Drinking alcohol with Clopitorva 10 Capsule may damage your liver and increase liver enzymes like transaminase. So, Clopitorva 10 Capsule should be used with caution by those who consume alcohol and/or have a past history of liver disease.

If you accidentally take an overdose of Clopitorva 10 Capsule you may have liver problems (increased secretion of liver enzymes) and bleeding complications. If problems persist you should immediately go to the nearby clinic or hospital.

You should have a total lipid profile (TG, HDL, LDL, VLDL, TC) and Blood coagulation tests like Complete blood count (CBC), Factor V assay, Fibrinogen Test, Prothrombin time (PT or PT-INR), Platelet count, Thrombin time and Bleeding time to analyze your blood clot timing and cholesterol level.

Clopitorva 10 Capsule may cause acidity in some cases. Stick to simple meals and avoid spicy food. Do not lie down immediately after eating, as it might cause acidity.

Include fruits, vegetables, and whole grains in your diet. Avoid smoking and drinking, and try to work out every day.

Do not discontinue Clopitorva 10 Capsule without consulting your doctor. Stopping using Clopitorva 10 Capsule may worsen your condition and increase your risk of a future heart attack. To treat your condition effectively, keep taking Clopitorva 10 Capsule for the prescribed duration.

Yes, Clopitorva 10 Capsule is good for cholesterol. It lowers bad cholesterol and increases the levels of good cholesterol.

As Clopitorva 10 Capsule may increase the risk of bleeding, the doctor may ask you to stop taking Clopitorva 10 Capsule before surgery or a dental procedure. Inform the doctor that you are taking Clopitorva 10 Capsule if you are due to undergo any surgery.

A low cholesterol diet along with a regular exercise regime is found to complement treatment with Clopitorva 10 Capsule effectively. Avoid fast foods, fried and processed foods.

Paracetamol may be safe while taking Clopitorva 10 Capsule as other painkillers may increase the risk of bleeding. However, consult the doctor before taking any painkillers with Clopitorva 10 Capsule .

Consult the doctor before taking other medicines like antibiotics, anti-HIV drugs, antifungal medication, blood thinners, anti-arthritis drugs, heart-related medicines and immune system-affecting drugs with Clopitorva 10 Capsule .

Store Clopitorva 10 Capsule at room temperature, in a dry place. Keep out of sight and reach of children.

Side effects of Clopitorva 10 Capsule include headaches, ankle swelling (oedema), slow heart rate, and nausea. If the side effects are persistent, reach out to your doctor.

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Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - CLO1623
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