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compositionComposition:CLOBETASOL-0.05%W/W+GENTAMICIN-0.1%W/W
prescription
Prescription Medicine
info
Clotof G Cream
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

CLOBETASOL-0.05%W/W+GENTAMICIN-0.1%W/W

Manufacturer/Marketer :

Osmed Formulations Pvt Ltd

Consume Type :

Topical

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Clotof G Cream

Clotof G Cream is a prescription topical medication used to treat inflammatory skin conditions that have a bacterial infection or are at a high risk of developing one. It helps relieve symptoms like severe itching, redness, swelling, and scaling associated with eczema, psoriasis, or dermatitis while clearing the underlying bacterial infection.

To get the best results, you should apply Clotof G Cream consistently at the exact times recommended by your doctor, usually once or twice daily. Because this is a topical cream, it does not need to be used with food, but you should apply it only to clean, dry skin. Making simple lifestyle adjustments, such as wearing loose cotton clothing and avoiding known skin irritants, can significantly support your skin's recovery.

While using Clotof G Cream, you may notice mild local reactions such as a slight burning or stinging sensation where you applied the cream. However, if you experience more serious issues like severe skin thinning, stretch marks, skin colour changes, or signs of a spreading skin infection, you should contact your doctor right away.

Before starting this treatment, tell your doctor if you have skin thinning, poor blood circulation, or a weakened immune system. Do not use this cream if you have viral skin infections (like shingles or herpes), fungal infections, tuberculosis of the skin, or if you are allergic to any of its ingredients.

Although topical absorption is generally low, using other topical steroid creams at the same time can increase your risk of side effects. It is highly recommended that pregnant women, breastfeeding mothers, and elderly patients consult their healthcare provider before using this medicine to ensure it is completely safe for their specific situation.

Uses of Clotof G Cream

Your doctor may prescribe this medicine to treat several conditions, including:

  • Infected eczema and dermatitis: Clotof G Cream reduces the intense itching and swelling of eczema while killing the complicating bacterial infection.
  • Infected psoriasis: It helps clear up stubborn, scaly plaques and manages any secondary bacterial infections in the affected areas.
  • Inflammatory skin infections: It targets both the underlying inflammation (redness, warmth, swelling) and the bacterial pathogens causing the infection.
     

Key Benefits

  • Clotof G Cream provides targeted skin relief by addressing inflammation and bacterial infection at the affected area. By reducing irritation and supporting skin repair, this medicine offers several key health benefits:
  • Rapid Relief from Itching and Skin Inflammation: Clotof G Cream helps calm irritated, inflamed skin, reducing itching and discomfort so you can sleep better and carry out daily activities more comfortably.
  • Faster Healing of Infected Skin: By treating both inflammation and bacterial infection together, Clotof G Cream supports the healing of cracked, damaged, or oozing skin and helps prevent the condition from worsening.
  • Restoration of the Skin Barrier: Clotof G Cream helps repair and protect the skin’s natural barrier, reducing further irritation and lowering the risk of complications such as scarring caused by repeated scratching.
     
Side effects of Clotof G Cream
  • Avoid extreme heat or cold, like hot showers or cold winds, to prevent worsening skin discomfort.
  • Cool compresses: To reduce itch, redness, and swelling.
  • Avoid irritants like harsh chemicals or allergens to prevent worsening skin discomfort.
  • If you have severe itching, burning, or blistering seek medical attention.
  • Mild hair follicle inflammation often heals on its own without needing treatment.
  • You can apply a warm saltwater or vinegar solution to the affected area with a washcloth, or use over-the-counter antibiotics, oatmeal lotion, or hydrocortisone cream for relief.
  • Avoid making the affected area worse by not shaving, scratching, or wearing tight clothes.
  • Apply a warm compress to the area 3-4 times a day for 15-20 minutes to help speed up healing.
  • Do not scratch, squeeze, or pop any bumps, as this may lead to infection or other problems.
  • If self-care methods fail, consult a doctor for further treatment and advice.
  • Shield your skin from the sun by using sunscreen, seeking shade, and wearing protective clothing.
  • Please don't smoke, as it damages the skin and reduces blood flow.
  • Treat your skin gently by limiting bath time, using mild cleansers, and shaving carefully.
  • Eat a healthy diet of fruits, vegetables, whole grains, and lean proteins.
  • Stay hydrated by drinking plenty of water.
  • Manage stress through sleep, exercise, meditation, and enjoyable activities.
  • Additionally, use moisturizers to coat your skin with a protective barrier, and consider wearing sun-protective clothing.
  • Apply moisturizer immediately after showering or bathing.
  • Use a moisturizer containing lanolin, petroleum jelly, glycerine, hyaluronic acid or jojoba oil.
  • Do not use hot water for bathing. Instead use warm water and limit showers and bath to 5 to 10 minutes.
  • Apply a sunscreen with SPF-30 or higher.
  • Avoid harsh soaps, detergents and perfumes.
  • Do not scratch or rub the skin.
  • Drink adequate water to prevent dehydration.
  • Wear pants, full sleeves and a wide-brimmed hat while going out in the sun.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

Always use this medicine exactly as your doctor has instructed. Follow these step-by-step guidelines:

  • Wash your hands thoroughly with soap and water before and after application.
  • Clean and dry the affected skin area gently.
  • Apply a thin film of the cream to the affected area and rub it in gently as directed by your doctor.
  • Do not cover the treated area with bandages, dressings, or wraps unless specifically told to do so by your doctor, as this can increase absorption and the risk of side effects.
  • Avoid getting the cream in your eyes, nose, or mouth. If contact occurs, rinse thoroughly with cool water.

Always follow your doctor's exact instructions regarding how long to use this medication. Do not apply more than prescribed, or use it for longer than advised.
 

How Clotof G Cream Works

Clotof G Cream contains gentamicin and clobetasol. It works through the combined action of its two active components: a highly potent topical corticosteroid and an aminoglycoside antibiotic. The corticosteroid component targets the body's inflammatory response. It stops the release of chemical messengers that cause blood vessels to widen, which directly reduces redness, swelling, and severe itching in the affected area. The antibiotic component works by stopping the growth of bacteria on the skin. It binds to the bacterial machinery, preventing the bacteria from producing essential proteins they need to survive and multiply, which successfully clears the skin infection.
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Alcohol

Caution

It is not known whether Clotof G Cream interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

Consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Do not apply Clotof G Cream on the chest if you are breastfeeding. Please consult your doctor if you have any concerns regarding this, your doctor will decide whether Clotof G Cream can be used by breastfeeding mothers or not.

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Driving

Safe if prescribed

Clotof G Cream has no or negligible influence on the ability to drive or use machines.

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Liver

Caution

Please consult your doctor if you have any concerns regarding the usage of Clotof G Cream in patients with liver impairment.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of Clotof G Cream in patients with kidney impairment.

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Children

Caution

Clotof G Cream should be used with caution in children, only when prescribed by a child specialist.

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Heart

Consult your doctor

Please consult your doctor before using Clotof G Cream if you have pre-existing heart problems. Your doctor will prescribe Clotof G Cream if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before giving Clotof G Cream to geriatric patients. Your doctor will prescribe Clotof G Cream if the benefits outweigh the risks

What if I have taken an overdose of Clotof G Cream

Do not apply Clotof G Cream in large amounts or use it for a long time than recommended, as it does not give quick or better results but increases the risk of side effects.

Diet & Lifestyle Advise

  • Wear loose clothing: Choose soft, breathable fabrics like cotton to prevent friction and sweat buildup, which can worsen skin irritation and infections.
  • Avoid scratching: Keep your fingernails short and clean. Scratching damages the skin barrier further and can introduce new bacteria, delaying your recovery.
  • Moisturise safely: Use mild, fragrance-free moisturisers on non-infected areas of your skin to maintain hydration, but check with your doctor before applying other products directly over the treated area.
  • Take lukewarm baths: Avoid hot showers or baths, as hot water strips natural oils from your skin and can trigger severe itching and redness. Use mild, soap-free cleansers.
     

Have a query?

How Soon It Starts Working

The time required for Clotof G Cream to start to work: The time required for Clotof G Cream to show its action is unknown. The time for which the effects of Clotof G Cream last: The duration of action for Clotof G Cream is unknown.

What if you forget to take Clotof G Cream

Apply the missed dose as soon as you can. If it is almost time for the next dose, skip the missed dose and follow your regular schedule. Do not apply an extra amount of Clotof G Cream to make up for the missed dose.

Storage

Store Clotof G Cream at room temperature, ideally between 15°C and 30°C (59°F to 86°F). Keep the tube tightly closed when not in use to protect the cream from moisture and air exposure.

Drug Warnings

  • Do not apply this cream to your face, groin, or underarms unless explicitly instructed by your doctor, as these skin areas are thin and absorb the medication much faster.
  • Inspect the cream before use; do not use it if the tube is punctured, leaking, or if the cream has changed color or developed an unusual smell.
  • Do not use this medication for more than 2 consecutive weeks unless directed by your healthcare provider, to prevent skin thinning or adrenal gland suppression.
  • Avoid applying the cream to open wounds, deep cuts, or severely burned skin.
  • If your skin condition does not improve within a few days of starting treatment, or if it gets worse, contact your doctor for advice.
  • GENTAMICIN is a topical antibiotic and should not be used longer than recommended by your doctor or as a preventive treatment for repeated skin infections.
  • Use of GENTAMICIN in children should be based on medical advice. Safety and effectiveness may vary depending on the child’s age and the condition being treated.
  • It is generally avoided in very young children, including infants below 1 year, unless specifically prescribed by a doctor.
  • Treatment duration should be kept as short as possible to reduce the risk of side effects and antibiotic resistance.
     

Drug-Drug Interactions

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Drug-Drug Interactions:

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Other topical corticosteroids: Using other steroid creams or ointments at the same time can increase the risk of skin thinning and systemic absorption.
  • Oral corticosteroids: Combining this topical treatment with oral steroids can increase the risk of system-wide side effects, such as adrenal gland suppression.

Drug-Disease Interactions:

Inform your doctor if you have a history of the following conditions before taking Clotof G Cream, as it may worsen your condition or cause complications.

  • Skin infections (viral or fungal): Using this medication on untreated viral (like chickenpox or herpes) or fungal skin infections can make the infection worse because the steroid suppresses the local immune response.
  • Diabetes: Large amounts absorbed through the skin may occasionally affect blood sugar control; monitor your blood sugar closely if you have diabetes and use this cream over large areas.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS AND CORTICOSTEROIDS]

FAQs

Clotof G Cream is used to treat skin infections caused by bacteria.

Clotof G Cream is a combination of two drugs: Gentamicin and Clobetasol. Gentamicin works by preventing the synthesis of essential proteins required for the survival of the bacteria. Clobetasol works by inhibiting the release of chemical messengers that cause inflammation and redness. Together, Clotof G Cream helps in treating skin infections.

Clotof G Cream should not be used for longer durations unless prescribed by a doctor. If your condition does not improve despite using Clotof G Cream for 2-4 weeks, consult your doctor, he/she may prescribe you an alternate medicine.

To treat your condition effectually, continue using Clotof G Cream for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Clotof G Cream.

Yes, Clotof G Cream can be used on the face if prescribed by the doctor. However, do not apply Clotof G Cream directly on the face. Take the required quantity of Clotof G Cream onto your finger and gently massage it onto the affected areas of the face.

No, Clotof G Cream contains Gentamicin which is an antibiotic; it should not be used for fungal and viral skin infections.

Yes, Clotof G Cream contains a steroid. It is a combination of clobetasol and gentamicin which belongs to the group of medicines called corticosteroids and antibiotics respectively. It is used in the treatment of bacterial skin infections.

You can use Clotof G Cream everyday if doctor has prescribed it. Use Clotof G Cream in the dose and duration advised by the doctor.

Store in a cool and dry place away from sunlight. Keep it out of sight and reach of children.

Avoid contact with eyes or mucous membranes; if contact occurs, rinse with water thoroughly. Do not use Clotof G Cream for longer than the prescribed period of time. Do not apply a bandage or dressing directly over the affected area unless advised by the doctor. Consult the doctor before using Clotof G Cream if you are pregnant or breastfeeding.

Clotof G Cream is for external use only. Clean and dry the affected area. Apply Clotof G Cream directly on to the affected area and gently massage it in.

No, you should not use Clotof G Cream on your face or to treat acne. The strong steroid component can worsen acne, cause skin thinning, and lead to other skin issues on the face. Talk to your doctor for safe face-specific treatments.

Many patients begin to notice relief from itching and redness within a few days of regular use. However, you must complete the full course prescribed by your healthcare provider, even if your skin looks better sooner. If you see no improvement after a week, talk to your doctor.

Clotof G Cream should only be used during pregnancy if the potential benefits outweigh the risks, and under strict medical supervision. High-potency topical steroids can sometimes affect the baby if used over large areas or for long periods. Talk to your doctor before starting this treatment.

No, Clotof G Cream is not suitable for diaper rash or fungal infections, and it should not be used on infants without explicit medical advice. The strong steroid can be quickly absorbed through a baby's thin skin and cause harm. Talk to your doctor for appropriate diaper rash treatments.

Skin thinning is a known side effect of prolonged topical steroid use. If you notice your skin becoming thin, easily bruised, or developing stretch marks, stop applying the cream and contact your healthcare provider immediately. Talk to your doctor to find an alternative treatment.

Yes, but you should wait at least 15 to 30 minutes after applying Clotof G Cream before putting on any moisturiser. This gives the medication enough time to absorb into the skin without being diluted or wiped away. Talk to your doctor or pharmacist for a recommended skincare routine.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India
Other Info - CL85350
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