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compositionComposition:COLCHICINE-0.5MG
prescriptionPrescription Medicine
Colchicindon 0.5mg Tablet

Colchicindon 0.5mg Tablet is used to prevent and treat gout attacks and relieve the pain of gout attacks. It is also used to treat familial Mediterranean fever. Additionally, colchicine is also used to reduce the risk of heart attack, stroke, and cardiovascular death. The medicine helps control symptoms but does not cure the underlying condition, so it should be taken exactly as prescribed by a doctor.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

COLCHICINE-0.5MG

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Colchicindon 0.5mg Tablet

Colchicindon 0.5mg Tablet is used to treat gout attacks and relieve their pain. Additionally, colchicine is also used to reduce the risk of heart attack, stroke, cardiovascular death, and needing certain types of heart procedures such as angioplasty or coronary artery bypass grafting in patients who have atherosclerosis.

Colchicindon 0.5mg Tablet contains Colchicine, which works by stopping the natural processes that cause swelling and other symptoms of gout and familial Mediterranean fever. It helps lower the risk of heart problems and stroke by inhibiting white blood cells that cause inflammation.

In some cases, Colchicindon 0.5mg Tablet may cause side effects like diarrhoea, nausea, vomiting, and abdominal pain. Most of these side effects may not need medical attention and will gradually resolve over time. However, if any of the side effects persist or worsen, consult your doctor.

Do not take Colchicindon 0.5mg Tablet if you are allergic to any of its components. Inform the doctor if you have a blood disorder, liver/kidney/heart problems, or are pregnant or breastfeeding. Keep the doctor informed about your health conditions and medications to prevent any interactions/side effects.

Uses of Colchicindon 0.5mg Tablet

Colchicindon 0.5mg Tablet is used to treat and prevent gout attacks. The detailed uses of Colchicindon 0.5mg Tablet are as follows:

  • Prevention and treatment of gout: Colchicindon 0.5mg Tablet used to treat gout attacks. It is also used to prevent flare-ups of gout when treatment is started with other drugs. It stops the natural processes that cause swelling and other gout symptoms.
  • Treatment of familial Mediterranean fever: Colchicine is also used to treat familial Mediterranean fever in adults and children 4 years of age and older. It prevents fever attacks and amyloidosis (abnormal protein precipitation in tissues and organs).

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Directions for Use

  • Colchicindon 0.5mg Tablet can be taken with or without food.
  • Follow the dosage and duration of treatment as advised by the doctor.
  • Swallow the medicine as a whole with water.
  • Do not crush, break or chew it.

Key Benefits

  • Reduces gout discomfort: Aids in the reduction of acute gout attacks' pain, swelling, and redness.
  • Prevents gout flare-ups: Frequent use can help prevent recurrent gout episodes.
  • Reduces inflammation brought on by uric acid crystal accumulation in joints.
  • Prevents recurrent episodes of fever and inflammation in familial Mediterranean fever.
  • Aids in pericarditis: Used to lessen inflammation and stop the inflammation of the heart lining from coming back.

How Colchicindon 0.5mg Tablet Works

Colchicindon 0.5mg Tablet contains Colchicine, which works by stopping the natural processes that cause swelling and other symptoms of gout and familial Mediterranean fever.

Storage

Store in a cool and dry place away from sunlight
Side effects of Colchicindon 0.5mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink plenty of fluids and stay hydrated.
  • Avoid foods containing sugars, salts and processed food.
  • Avoid consumption of alcohol.
  • Take healthy diet containing fiber, carbohydrates and lean proteins.
  • Exercise regularly and maintain a healthy lifestyle.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Drink plenty of water to eliminate uric acid.
  • Avoid purine-rich foods such as red meat, organ meats, certain seafood (sardines, anchovies) and too much alcohol.
  • Regularly do low impact exercises like swimming or walking.
  • To reduce pain and swelling, apply ice packs to the affected area.
  • Take rest and avoid activities that strain the affected joint.
  • Elevate the affected joint to encourage fluid drainage.
  • Aim for weight loss and maintain a healthy body weight to reduce the risk of gout.

What if I have taken an overdose of Colchicindon 0.5mg Tablet

Do not take more than the prescribed dose of Colchicindon 0.5mg Tablet as it may cause an overdose. The symptoms of overdose include nausea, vomiting, diarrhoea, stomach pain, slowed breathing, sore throat/fever/chills and other signs of infection, unusual bruising or bleeding, paleness or greyness of the lips/tongue/palms and slowed heartbeat. If you suspect you have taken an overdose or notice any symptoms of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Colchicindon 0.5mg Tablet if you're allergic to any of its components, if you have severe blood problems, severe liver or kidney problems, or are undergoing dialysis.
  • Consult the doctor if you are pregnant or breastfeeding.
  • Inform the doctor if you have blood problems, kidney/liver/heart problems, or are elderly and weak.
  • Avoid exceeding the recommended dose as it can be toxic.
  • Do not start a new medicine without consulting the doctor.
  • Let the doctor know if you have any other medical conditions or are taking other medicines, including supplements or herbal products.

Drug-Drug Interactions

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ColchicineItraconazole
Critical
ColchicineDarunavir
Critical

Drug-Drug Interactions

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ColchicineItraconazole
Critical
How does the drug interact with Colchicindon 0.5mg Tablet:
Coadministration of Colchicindon 0.5mg Tablet with itraconazole may increase the blood levels of Colchicindon 0.5mg Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Colchicindon 0.5mg Tablet with itraconazole can be taken if prescribed by a doctor, despite the possibility of an interaction. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.
ColchicineDarunavir
Critical
How does the drug interact with Colchicindon 0.5mg Tablet:
Coadministration of Colchicindon 0.5mg Tablet with darunavir may increase the blood levels of Colchicindon 0.5mg Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Taking Colchicindon 0.5mg Tablet with Darunavir is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
ColchicineClarithromycin
Critical
How does the drug interact with Colchicindon 0.5mg Tablet:
Coadministration of Colchicindon 0.5mg Tablet with clarithromycin may increase the blood levels of Colchicindon 0.5mg Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Taking Colchicindon 0.5mg Tablet with Clarithromycin is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
ColchicineKetoconazole
Critical
How does the drug interact with Colchicindon 0.5mg Tablet:
Using Colchicindon 0.5mg Tablet together with ketoconazole may increase the blood levels of Colchicindon 0.5mg Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Although taking Ketoconazole with Colchicindon 0.5mg Tablet is not recommended as it can cause an interaction, they can be taken if prescribed by a doctor. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without consulting a doctor
ColchicineAmiodarone
Severe
How does the drug interact with Colchicindon 0.5mg Tablet:
Coadministration of amiodarone with Colchicindon 0.5mg Tablet may increase the Colchicindon 0.5mg Tablet levels, leading to an increased risk or severity of side effects.

How to manage the interaction:
Taking amiodarone and Colchicindon 0.5mg Tablet together can lead to an interaction, but they can be taken together if your doctor has advised it. However, consult a doctor if you experience abdominal discomfort, diarrhoea, fever, muscle pain, tiredness, weakness, and numbness or tingling in your hands and feet. Do not discontinue any medications without consulting a doctor.
ColchicinePropafenone
Severe
How does the drug interact with Colchicindon 0.5mg Tablet:
Coadministration of Colchicindon 0.5mg Tablet and propafenone may increase the blood levels of Colchicindon 0.5mg Tablet, increasing the risk of side effects.

How to manage the interaction:
Although taking Colchicindon 0.5mg Tablet and Propafenone together may possibly result in an interaction, they can be taken together if your doctor prescribes it. However, contact your doctor immediately if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness. Do not discontinue any medication without consulting your doctor.
ColchicineLomitapide
Severe
How does the drug interact with Colchicindon 0.5mg Tablet:
Coadministration of Colchicindon 0.5mg Tablet and lomitapide may increase the blood levels of Colchicindon 0.5mg Tablet to dangerous level, increasing the risk of serious side effects.

How to manage the interaction:
Although there is a possible interaction between Colchicindon 0.5mg Tablet and Lomitapide, you can take these medicines together if prescribed by your doctor. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.
ColchicineCarvedilol
Severe
How does the drug interact with Colchicindon 0.5mg Tablet:
Coadministration of Colchicindon 0.5mg Tablet with Carvedilol increases Colchicindon 0.5mg Tablet levels in the blood, leading to increased side effects.

How to manage the interaction:
Although taking Colchicindon 0.5mg Tablet and Carvedilol together may possibly result in an interaction, they can be taken together if your doctor prescribes it. However, if you experience any symptoms like vomiting, stomach pain, muscle pain, or weakness, contact your doctor immediately. Do not discontinue any medication without consulting your doctor.
ColchicineAtorvastatin
Severe
How does the drug interact with Colchicindon 0.5mg Tablet:
coadministration of atorvastatin with Colchicindon 0.5mg Tablet can increase the risk of kidney problems.

How to manage the interaction:
Co-administration of atorvastatin with Colchicindon 0.5mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, diarrhea, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet, consult the doctor. Do not stop using any medications without talking to a doctor.
ColchicineSaquinavir
Severe
How does the drug interact with Colchicindon 0.5mg Tablet:
Coadministration of Colchicindon 0.5mg Tablet and saquinavir may increase the blood levels of Colchicindon 0.5mg Tablet, increasing the risk of serious side effects.

How to manage the interaction:
Although taking Colchicindon 0.5mg Tablet and Saquinavir together may possibly result in an interaction, they can be taken together if your doctor prescribes it. However, contact your doctor immediately if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

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COLCHICINE-0.5MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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COLCHICINE-0.5MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming excessive quantities of grapefruit juice can raise the levels of Colchicindon 0.5mg Tablet in your blood, increasing the risk of side effects. Avoid the consumption of grapefruit juice while taking Colchicindon 0.5mg Tablet.

Diet & Lifestyle Advise

Diet

  • To assist the body get rid of extra uric acid, drink lots of water.
  • To help avoid gout attacks, cut back on high-purine meals including red meat, organ meats, and some shellfish.
  • For improved general health, eat more fruits, vegetables, and whole grains.
  • Alcohol, particularly beer, should be avoided or used in moderation as it can raise the risk of gout flare-ups.

Precautions

  • Follow heat or cold therapy by regularly applying a cold or hot compress to the joints for 15-20 minutes.
  • Relax by meditating, reading, enjoying a bubble bath, or listening to calming music.

Lifestyle changes

  • Maintain a healthy body weight to reduce pressure on joints and lower the risk of gout attacks.
  • Exercise regularly with light to moderate activities like walking to improve joint health.
  • Avoid activities that may strain painful joints, especially during a gout attack.

Habit Forming

No

Therapeutic Class

[ANTI- GOUT MEDICATIONS]

All Substitutes & Brand Comparisons

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Alcohol

Consult your doctor

It is not known if alcohol interacts with Colchicindon 0.5mg Tablet. Please consult the doctor.

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Pregnancy

Consult your doctor

Please consult the doctor if you are pregnant, as it is not known if colchicine will harm the unborn baby.

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Breast Feeding

Consult your doctor

Colchicine may pass into breastmilk. Please consult the doctor if you are breastfeeding.

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Driving

Caution

Colchicindon 0.5mg Tablet may cause dizziness. Therefor, drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Colchicindon 0.5mg Tablet is not recommended for people with severe liver problems. Please consult the doctor if you have liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Colchicindon 0.5mg Tablet is not recommended for people with severe kidney problems. Please consult the doctor if you have kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Colchicindon 0.5mg Tablet should be used for children under 12 only when prescribed by a child specialist.

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Heart

Safe if prescribed

Colchicindon 0.5mg Tablet can be used in patients with heart disease if prescribed by a physician to reduce cardiovascular problems. Please consult your physician if you have any concerns.

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Geriatrics

Caution

Geriatric patients can take Colchicindon 0.5mg Tablet under extreme caution if prescribed by the physician. It's important to use it under close medical supervision with tailored dosing and regular monitoring.

FAQs

Colchicindon 0.5mg Tablet is used to treat and prevent acute attacks or flare-ups of gout. It is also used to treat familial Mediterranean fever. Additionally, colchicine is also used to reduce the risk of heart attack, stroke, and cardiovascular death in patients who have or who have multiple risk factors for developing heart and blood vessel disease.

Colchicindon 0.5mg Tablet works by stopping the natural processes that cause swelling and other symptoms of gout and familial Mediterranean fever.

Colchicindon 0.5mg Tablet is usually prescribed for a short period of time. Consult the doctor if your condition persists or worsens; the doctor may prescribe an alternate medicine.

No, do not exceed the recommended dosage as it will not help treat your condition faster. Avoid exceeding the recommended dose as colchicine can be toxic. Take Colchicindon 0.5mg Tablet only as prescribed by the doctor.

Do not stop taking Colchicindon 0.5mg Tablet without consulting the doctor. To treat your condition effectively, take Colchicindon 0.5mg Tablet for as long as prescribed by your doctor.

Colchicindon 0.5mg Tablet may cause blood problems, including myelosuppression, leukopenia, granulocytopenia, thrombocytopenia, and aplastic anaemia. Consult the doctor if you notice pale or grey-coloured lips, tongue, or palms; unusual bleeding or bruising; feel weak or tired; or experience increased infections.

The early symptoms the patient can identify if he/she is suffering from gout include sudden, intense joint pain, often in the big toe. The area can become red, warm, swollen, and tender, making moving difficult. These symptoms usually appear suddenly, especially at night. If you notice these signs, seeing a doctor for appropriate care and to prevent acute attacks is essential.

Colchicindon 0.5mg Tablet may cause muscle problems. Seek medical attention if you experience muscle pain, weakness, numbness or tingling sensations.

Diarrhoea is the most frequently reported side effect associated with Colchicindon 0.5mg Tablet. If you experience severe or worsening diarrhoea, notify your doctor for guidance on managing it. But, do not self-medicate with loperamide or any other anti-diarrheal medication without consulting a doctor, as this may interfere with Colchicindon 0.5mg Tablet efficacy or may lead to potential interactions.

Never split medication tablets unless your doctor advises. This ensures accurate dosing and prevents potential complications. Consult your healthcare provider or pharmacist before splitting any medication.

Yes, like all medications, Colchicindon 0.5mg Tablet also expires. Before using the Colchicindon 0.5mg Tablet, always verify the expiration date printed on the packaging. Never take expired Colchicindon 0.5mg Tablet to avoid negative complications. Consult a doctor or pharmacist to get fresh medication.

Colchicindon 0.5mg Tablet is not intended to cause weight loss. Due to the underlying condition being treated and the common side effects of Colchicindon 0.5mg Tablet, such as weakness, slight weight loss may occur. However, this symptom vanishes over time. If you're concerned about weight changes while taking Colchicindon 0.5mg Tablet, consult your healthcare provider for personalised guidance.

Hair loss is not a common side effect of Colchicindon 0.5mg Tablet. Suppose you experience hair loss or thinning while taking Colchicindon 0.5mg Tablet. In that case, it's best to consult a doctor to determine the reason for the hair loss and discuss possible alternatives or solutions.

Colchicindon 0.5mg Tablet is not typically known to raise blood sugar levels. However, individual responses to medication can vary. If you have concerns about your blood sugar while taking Colchicindon 0.5mg Tablet, inform your doctor. They may undergo a glucose level monitoring program and consult their doctor for personalized advice.

Yes, Colchicindon 0.5mg Tablet may increase liver damage risk, especially for those with liver issues or taking liver-affecting medications. Before taking Colchicindon 0.5mg Tablet, inform the doctor about any pre-existing liver conditions and current medications. The doctor will provide personalized guidance, as caution is advised for patients with regular liver function monitoring is crucial while on Colchicine.

The common side effects of the Colchicindon 0.5mg Tablet that usually occur while using it are nausea, vomiting, diarrhoea, abdominal pain, and fatigue. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.

If you forget a dose of Colchicindon 0.5mg Tablet, take it immediately when you remember. However, if your next dose is near, skip the missed dose and continue with your regular schedule. Never double dose to make up for a missed dose, as this may increase side effects.

Manufacturer/Marketer address

Scf 1013 2nd Floor, M Market Manimajra, Chandigarh, 160 101
Other Info - CO79082

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