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  3. COLIGAN TABLET

COLIGAN TABLET, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

COLIGAN TABLET is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. It contains Dicyclomine and Mefenamic acid which relieve contractions associated with the smooth muscles of the abdomen and reduce mild to moderate pain and inflammation. It may cause common side effects such as nausea, vomiting, diarrhoea, dry mouth, and weakness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Synonym :

DICYCLOMINE HYDROCHLORIDE+MEFENAMIC ACID

Composition :

DICYCLOMINE-20MG + MEFENAMIC ACID-500MG

Manufacturer/Marketer :

Fourrts India Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About COLIGAN TABLET

COLIGAN TABLET is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. Abdominal (tummy) pain occurs between the chest and pelvic region (below the belly button and leg). Menstrual cramps, also known as dysmenorrhea, are characterised by cramps and pain during menstruation. A colic is a form of pain that starts and stops abruptly.

COLIGAN TABLET is a combination of two drugs: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Together, COLIGAN TABLET helps in relieving pain.

You are advised to take COLIGAN TABLET as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, COLIGAN TABLET may cause common side effects such as nausea, vomiting, diarrhoea, dry mouth, and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. COLIGAN TABLET may cause dizziness and drowsiness, so drive with caution. COLIGAN TABLET is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with COLIGAN TABLET as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of COLIGAN TABLET

COLIGAN TABLET is used in the treatment of abdominal pain, dysmenorrhea (period pain), and colicky pain. The detailed uses of COLIGAN TABLET are as follows:

  • Menstrual Pain Relief: COLIGAN TABLET is used to relieve menstrual cramps (dysmenorrhea) by relaxing the uterine muscles, reducing pain and discomfort during periods.
  • Abdominal Pain Treatment: COLIGAN TABLET helps to relieve abdominal pain and cramps caused by digestive issues by relaxing intestinal muscles and reducing spasms.
  • Colicky pain: COLIGAN TABLET treats colicky pain by relaxing muscles and reducing inflammation and pain.
  • Management of Muscle Spasms: COLIGAN TABLET helps relieve muscle spasms, providing comfort and relaxation to affected areas, particularly in the gastrointestinal tract.

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Directions for Use

• Take COLIGAN TABLET with food to avoid any stomach upset. • It is advised to take COLIGAN TABLET once daily, or as directed by your doctor, at the same time each day for best results. • Swallow COLIGAN TABLET as a whole with a glass of water. • Do not crush, chew, or break it.

Medicinal Benefits

COLIGAN TABLET is a combination of two drugs: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). COLIGAN TABLET is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Together, COLIGAN TABLET helps in relieving pain.

How COLIGAN TABLET Works

COLIGAN TABLET is a combination of two drugs: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Together, COLIGAN TABLET helps in relieving pain.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Coligan Tablet
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of COLIGAN TABLET

Do not take more than the prescribed dose of COLIGAN TABLET as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take COLIGAN TABLET if you are allergic to any of its contents, if you have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. Inform your doctor if you have/had asthma, glaucoma, myasthenia gravis, high blood pressure, inflammatory bowel disease, paralytic ileus, intestinal atony, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. COLIGAN TABLET may cause dizziness and drowsiness, so drive only if you are alert. COLIGAN TABLET should not be given to children as safety has not been established. Avoid consuming alcohol with COLIGAN TABLET as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking COLIGAN TABLET and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with COLIGAN TABLET unless prescribed. 

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
Mefenamic acidKetorolac
Critical

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
How does the drug interact with Coligan Tablet:
Co-administration of Coligan Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Coligan Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidKetorolac
Critical
How does the drug interact with Coligan Tablet:
Coadministration of Coligan Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Coligan Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
DicyclominePotassium citrate
Critical
How does the drug interact with Coligan Tablet:
Taking Coligan Tablet and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Coligan Tablet with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
DicyclominePotassium chloride
Critical
How does the drug interact with Coligan Tablet:
Co-administration of Coligan Tablet with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Coligan Tablet with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.
DicyclominePramlintide
Critical
How does the drug interact with Coligan Tablet:
Co-administration of Pramlintide with Coligan Tablet can increase the risk of reduced gastrointestinal movement.

How to manage the interaction:
Taking Coligan Tablet with Pramlintide is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
Mefenamic acidLeflunomide
Severe
How does the drug interact with Coligan Tablet:
Coadministration of Coligan Tablet with Leflunomide can increase the risk or severity of liver disease.

How to manage the interaction:
Taking Coligan Tablet with Leflunomide together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidTenofovir alafenamide
Severe
How does the drug interact with Coligan Tablet:
The combined use of Coligan Tablet and Tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Coligan Tablet and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Mefenamic acidIndometacin
Severe
How does the drug interact with Coligan Tablet:
The combined use of Indometacin and Coligan Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Indometacin with Coligan Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Mefenamic acidPrasugrel
Severe
How does the drug interact with Coligan Tablet:
Co-administration of Coligan Tablet with Prasugrel can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Coligan Tablet with Prasugrel together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidDasatinib
Severe
How does the drug interact with Coligan Tablet:
Co-administration of Coligan Tablet with Dasatinib can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Coligan Tablet with Dasatinib together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, lightheadedness, red or black tarry stools, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.

  • Massages can also be helpful.

  • Avoid freezing and hot temperatures.

  • Avoid wearing tight-fitting clothes, instead, wear loose garments.

  • Rest well, and get plenty of sleep.

  • To avoid developing pressure sores, change your position every two hours.

  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.

  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANTISPASMODICS

COLIGAN TABLET Substitute

Substitutes safety advice
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Alcohol

Unsafe

Avoid consumption of alcohol while taking COLIGAN TABLET as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Unsafe

It is not recommended to breastfeed while taking COLIGAN TABLET. Consult your doctor before taking COLIGAN TABLET if you are breastfeeding.

bannner image

Driving

Caution

COLIGAN TABLET may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Unsafe

COLIGAN TABLET should not be used in patients with renal disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

COLIGAN TABLET is not recommended for children as safety and effectiveness were not established.

FAQs

COLIGAN TABLET is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain.

COLIGAN TABLET contains Dicyclomine and Mefenamic acid. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the action of certain chemical messengers that cause pain.

Diarrhoea might be a side-effect of COLIGAN TABLET. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in your stools.

COLIGAN TABLET is used to treat colicky pain. Colic is a pain that is usually intestinal or urinary in nature that comes and goes and intensifies and eases gradually.

Dry mouth could be a side-effect of COLIGAN TABLET. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevents drying of the mouth.

COLIGAN TABLET should not be taken for more than 7days. Do not take COLIGAN TABLET for longer durations as it might increase the risk of heart problems and stomach bleeding.

COLIGAN TABLET is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take COLIGAN TABLET only as prescribed, and do not overdose.

No, COLIGAN TABLET may not cause infertility. Consult the doctor if you have any concerns.

Yes, it is safe to use COLIGAN TABLET during periods if prescribed by the doctor. It helps relieve period cramps.

COLIGAN TABLET may prolong prothrombin time (blood test to measure blood clotting time). Therefore, frequent monitoring of prothrombin time is advised while taking this medication.

COLIGAN TABLET starts working within an hour.

Do not take COLIGAN TABLET on an empty stomach. Take COLIGAN TABLET with meals or immediately after meals to prevent stomach upset.

No, COLIGAN TABLET is recommended for headaches and toothache. It is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain.

Yes, COLIGAN TABLET can be taken with food or immediately after food.

No, COLIGAN TABLET does not stop menstruation. It does not affect the menstrual bleeding or the duration of periods. It only helps relieve menstrual cramps.

COLIGAN TABLET should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.

COLIGAN TABLET may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.

Yes, COLIGAN TABLET is a painkiller. It contains Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). COLIGAN TABLET helps relieve abdominal pain, colicky pain, and period pains.

Yes, COLIGAN TABLET is safe if taken in the dose and duration prescribed by the doctor.

COLIGAN TABLET is not recommended for children as safety and effectiveness were not established.

COLIGAN TABLET should be used during pregnancy only if prescribed by the doctor. Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

COLIGAN TABLET may cause side effects such as nausea, vomiting, diarrhoea, dry mouth, and weakness. Talk to your doctor if these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

#1, Fourrts Avenue, Annai Indira Nagar, Okkiyam Thoraipakkam, Chennai, India.
Other Info - COL0248

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Aug 5, 2025 | 9:21 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://bluecrosslabs.com/wp-content/uploads/2021/01/MEFTAL-SPAS_DS_Tablets.pdf
  2. https://vibcare.co.in/dicyclomine-hydrochloride-mefenamic-acid-tablets/
  3. https://www.drugs.com/mtm/dicyclomine.html
  4. https://www.drugs.com/cdi/mefenamic-acid.html

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