Combither Syrup belongs to the class of 'anti-malarial drugs', primarily used to treat and prevent malaria in children. Malaria is a disease caused by a plasmodium parasite, transmitted by the bite of infected Anopheles mosquitoes. When an infected mosquito bites a healthy person, it sends the 'Plasmodium parasite' into the bloodstream, which affects the red blood cells and liver cells. Malaria symptoms typically begin 10 days to 4 weeks after infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma and bloody stools.

Combither Syrup contains two medicines, namely: Artemether and Lumefantrine. These are anti-malarial drugs that interfere with the Plasmodium parasite's growth in the red blood cells of the human body. Combither Syrup is a combination that is used to treat non-severe malaria caused by a parasite called 'Plasmodium falciparum,' and other Plasmodium species. It works by inhibiting nucleic acid and protein synthesis in Plasmodium falciparum. Artemether is known to reduce parasite biomass, and Lumefantrine eliminates residual parasites.

Your paediatrician will decide the dose and duration based on your child's medical condition. Common side effects of Combither Syrup include headache, dizziness, loss of appetite, weakness, fever, chills, tiredness, muscle/joint pain, nausea, vomiting, abdominal pain, cough and trouble sleeping. These side effects are not familiar to everyone and vary from person to person. If you notice any side effects that are not manageable, please consult your doctor.

Before using Combither Syrup, inform your doctor about any recently used prescription and non-prescription medications for your child, including other anti-malarial or antibiotic drugs. Let your doctor know if your child is allergic to Combither Syrup or its components. Let your doctor know if you have any liver or kidney problems, severe heart disease or electrolyte imbalance. This medicine is not recommended for use in pregnant and breastfeeding mothers as it is for pediatric use only.

• Combither Syrup should be given with food to prevent stomach upset or as advised by your doctor.
• Follow your doctor's instructions on the dosage and timing of this medication.
• Before giving, mix the contents with the sterile water provided along with the medicine. Make up the volume by adding more water.
• Shake the bottle well before use.

Combither Syrup contains two anti-malarial drugs, namely: Artemether and Lumefantrine. It is a combination that treats non-severe malaria caused by a parasite called 'Plasmodium falciparum', and other Plasmodium species. It interferes with the growth of Plasmodium parasites in the red blood cells of the human body. Combither Syrup works by inhibiting nucleic acid and protein synthesis in Plasmodium falciparum. Artemether reduces parasite biomass, and Lumefantrine eliminates residual parasites.

Let your doctor know if you use any antibiotic drugs on your child or have recently undergone treatment with other anti-malarial drugs. Brief your child's medical history to the doctor, like any liver or kidney problems, malarial infection of the brain, lungs or kidneys, severe heart diseases and electrolyte imbalance. It is essential to inform your doctor if your child has hypokalemia (low potassium levels) or hypomagnesemia (low magnesium levels) before using this medicine. Combither Syrup may affect QT prolongation, which can cause severe fast/irregular heartbeat. Hence, it is advised to inform your doctor if you have any heart-related problems like heart failure, slow heartbeat, QT prolongation in EKG or ECG (electrocardiogram), and a family history of heart diseases.