apollo
0
  1. Home
  2. Medicine
  3. Coxnil-P Tablet 10's

Offers on medicine orders
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Coxnil-P Tablet 10's is used for the symptomatic treatment of migraine and any medical condition with concomitant nausea/vomiting and fever/pain. It contains Domperidone and Paracetamol, which blocks certain receptors (like dopamine and serotonin) that stimulate the vomiting centre in the brain. It also increases the upper gastrointestinal tract's motility and helps in decreasing the stomach emptying time. It works by blocking the production of prostaglandins (chemicals) that are involved in pain and swelling. Some people may experience side effects such as, dry mouth, skin rash, anxiety, diarrhoea, and drowsiness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
Read more
rxMedicinePrescription drug

Whats That

tooltip

Manufacturer/Marketer :

Ficus Remedies

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Coxnil-P Tablet 10's

Coxnil-P Tablet 10's is used for the symptomatic treatment of migraine and any medical condition with concomitant nausea/vomiting and fever/pain. Migraine is a neurological condition that can cause severe throbbing pain or a pulsing sensation, usually on one side of the head, eyes, face, and neck. Symptoms may include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound.

Coxnil-P Tablet 10's is a combination of two drugs: Domperidone and Paracetamol. Domperidone prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone –CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps in decreasing the stomach emptying time. Paracetamol is an NSAID that works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical ‘prostaglandins’(PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Take Coxnil-P Tablet 10's as prescribed. Your doctor will recommend how often you take Coxnil-P Tablet 10's based on your medical condition. Some people may experience some side effects, dry mouth, skin rash, anxiety, diarrhoea, and drowsiness. Most of these side effects of Coxnil-P Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

You can increase the efficacy of Coxnil-P Tablet 10's by taking a small meal or snacks frequently. Do not take Coxnil-P Tablet 10's if you are allergic to Coxnil-P Tablet 10's and other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before taking Coxnil-P Tablet 10's. Inform your doctor if you have heart, kidney, and liver disease. Prolonged intake of Coxnil-P Tablet 10's may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or taking a higher dose. If you experience heart rhythm disorders like palpitations, trouble in breathing, or loss of consciousness after taking Coxnil-P Tablet 10's, immediately contact your doctor.

Uses of Coxnil-P Tablet 10's

Treatment of Migraine

Directions for Use

Take Coxnil-P Tablet 10's on an empty stomach or as advised by a doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Coxnil-P Tablet 10's is a combination of two drugs, Domperidone and Paracetamol, used to treat vomiting and pain in people with migraines. Domperidone belongs to a class of prokinetic agents that prevent nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone –CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps in decreasing the stomach emptying time. Paracetamol is an NSAID that works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical ‘prostaglandins’(PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Coxnil-P Tablet 10's together used to prevent nausea, vomiting, pain, and fever associated with migraine.

How Coxnil-P Tablet 10's Works

Coxnil-P Tablet 10's is a combination of two drugs: Domperidone and Paracetamol. Domperidone prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone –CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps in decreasing the stomach emptying time. Paracetamol is an NSAID that works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical ‘prostaglandins’(PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Coxnil-P Tablet 10's

Do not take more than the prescribed dose of Coxnil-P Tablet 10's as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Coxnil-P Tablet 10's if you are allergic to any of its contents or any other medicines, have a history of gastrointestinal bleeding, heart disease, liver/ kidney problem. Prolonged intake of Coxnil-P Tablet 10's may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). So, if you experience heart rhythm disorders like palpitations, trouble in breathing, or loss of consciousness after taking Coxnil-P Tablet 10's, immediately contact your doctor. This risk may be more likely in the elderly (those over 60 years old) or taking a higher dose. If you are pregnant or breastfeeding, inform your doctor before using Coxnil-P Tablet 10's. Avoid consumption of alcohol while using Coxnil-P Tablet 10's as it may increase the side effects and make worse your condition. Coxnil-P Tablet 10's should not be given to children below five years of age. The use of Coxnil-P Tablet 10's is safe in children above five years of age if prescribed by the doctor. Do not exceed dose paracetamol more than 4 gm per day as it can damage your liver.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions

Login/Sign Up

How does the drug interact with Coxnil-P Tablet:
Coadministration of Coxnil-P Tablet with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Coxnil-P Tablet and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Coxnil-P Tablet:
Coadministration of Coxnil-P Tablet with Ritonavir can increase the blood levels of Coxnil-P Tablet.

How to manage the interaction:
There may be a possibility of interaction between Coxnil-P Tablet and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
How does the drug interact with Coxnil-P Tablet:
Coadministration of Coxnil-P Tablet with Cisapride can increase the blood levels of Coxnil-P Tablet.

How to manage the interaction:
There may be a possibility of interaction between Coxnil-P Tablet and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Coxnil-P Tablet:
Coadministration of Coxnil-P Tablet with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Coxnil-P Tablet and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Coxnil-P Tablet:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Coxnil-P Tablet and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneToremifene
Severe
How does the drug interact with Coxnil-P Tablet:
Coadministration of Coxnil-P Tablet with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Coxnil-P Tablet and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Coxnil-P Tablet:
Coadministration of Coxnil-P Tablet with Nefazodone can increase the blood levels of Coxnil-P Tablet.

How to manage the interaction:
There may be a possibility of interaction between Coxnil-P Tablet and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
How does the drug interact with Coxnil-P Tablet:
Coadministration of Coxnil-P Tablet with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Coxnil-P Tablet and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Coxnil-P Tablet:
Coadministration of Coxnil-P Tablet with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Coxnil-P Tablet and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Coxnil-P Tablet:
Coadministration of Coxnil-P Tablet with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Coxnil-P Tablet and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over sweet food and include more salty food, especially if you have been vomiting.

  • Also, if you like vomiting at a specific time, avoid eating your favorite food at that particular time as your taste for that food may get turned off.

  • Include more cool beverages in your food like clear soup, flavored gelatin, carbonated beverages. Also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas and acidity.

  • Drink after or any other liquid at least 30 minutes after eating food. 

  • Avoid smoking and alcohol intake.

  • Avoid chronic stress as it can raise your migraine pain. Try to enjoy and spending time with your friends to cope with stress and practice mindfulness techniques.

Habit Forming

No

Therapeutic Class

ANTIMIGRAINE AGENTS
bannner image

Alcohol

Caution

Alcohol consumption with Coxnil-P Tablet 10's may cause sleepiness or an irregular heartbeat.

bannner image

Pregnancy

Caution

The safety of pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Coxnil-P Tablet 10's is not usually recommended when breastfeeding, as it passes into breast milk in a small amount. Therefore, it is given to breastfeeding women only if the doctor thinks the benefits outweigh the risks.

bannner image

Driving

Caution

Drive and operate machinery only if you are alert.

bannner image

Liver

Caution

Coxnil-P Tablet 10's to be taken with caution, especially if you have had a history of liver disease/condition. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Coxnil-P Tablet 10's to be taken with caution, especially if you have had a history of kidney disease/condition. The dose may have to be adjusted by your doctor.

bannner image

Children

Caution

Coxnil-P Tablet 10's should not be given to children below 5 years of age. Please consult your doctor. Your doctor will weigh the benefits and any potential risks before prescribing it to children.

Have a query?

FAQs

Coxnil-P Tablet 10's is used for the symptomatic treatment of migraine and any medical condition with concomitant nausea/vomiting and fever/pain.

Coxnil-P Tablet 10's is a combination of drugs namely; Domperidone and Paracetamol. Domperidone is a prokinetic that prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone - CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps in decreasing the stomach emptying time. Paracetamol is an NSAID that works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical ‘prostaglandins’(PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, used to prevent nausea, vomiting, pain, and fever associated with migraine.

Talk to your doctor if you do not feel better even after taking Coxnil-P Tablet 10's for 14 days. Do not take Coxnil-P Tablet 10's for longer durations unless prescribed by the doctor.

If you or someone else have taken too much of Coxnil-P Tablet 10's, contact your doctor or nearest hospital casualty department.

Yes, Coxnil-P Tablet 10's can cause dry mouth. In case you feel excessively thirsty, please increase your fluid intake and do frequent mouth rinses.

Coxnil-P Tablet 10's helps to relieve migraine headache. But it is not specifically formulated to relieve general headache. If you are experiencing a headache that is not related to a migraine, it’s always best to consult your doctor.

Yes, Coxnil-P Tablet 10's, which contains domperidone and paracetamol, can be used to treat fever. Paracetamol is an antipyretic (fever reducer) and analgesic (pain reliever) that helps reduce fever and alleviate pain, especially if it's accompanied by nausea or vomiting. Do not self-medicate.

No, you should not take a higher than the recommended dose of Coxnil-P Tablet 10's. Taking more than the prescribed dose can increase the risk of side effects and liver damage. It's important to follow your doctor's instructions regarding the dosage and duration of Coxnil-P Tablet 10's.

No, Coxnil-P Tablet 10's is not addictive. However, do not exceed the recommended daily dose. Consult your doctor if you have any concerns.

Yes, Coxnil-P Tablet 10's can cause liver damage, especially if taken in doses higher than recommended. It's important to follow your doctor's prescribed dosage and avoid alcohol while taking this medication, as it can further increase the risk of liver damage. If you have any pre-existing liver conditions, it's best to consult your doctor before using Coxnil-P Tablet 10's.

Store Coxnil-P Tablet 10's at room temperature in a cool and dry place away from sunlight. Keep it out of reach of children.

The common side effects of Coxnil-P Tablet 10's are dry mouth, skin rash, anxiety, diarrhoea, and drowsiness. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Tamil Nadu, India
Other Info - COX0105

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
whatsapp Floating Button
Buy Now
Add to Cart