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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Cozynil 5mg/5mg/325mg Tablet is used to treat the allergies and common cold symptoms like sneezing, runny/stuffy nose, watery eyes, and itchy nose/throat. It works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps in shrinking the blood vessels in the nasal passage, thereby reducing a stuffy nose. Also, it inhibits the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever. Some people may experience drowsiness, headache, tiredness, stomach upset, restlessness, and dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About Cozynil 5mg/5mg/325mg Tablet

Cozynil 5mg/5mg/325mg Tablet is a cough and cold medication used to treat allergies and common cold symptoms like sneezing, runny/stuffy nose, watery eyes, and itchy nose/throat. The common cold is a respiratory illness affecting the nose and throat, mostly caused by viruses known as 'rhinovirus'. This virus attacks the body through the mouth, nose, or eyes and spreads easily through droplets in the air when a person who is sick sneezes, coughs, or talks.

Cozynil 5mg/5mg/325mg Tablet is composed of three medicines, namely Levocetirizine (antihistamine/antiallergic), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing a stuffy nose. Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

Take Cozynil 5mg/5mg/325mg Tablet with or without food as prescribed by your doctor. Do not crush, chew, or break it. If Cozynil 5mg/5mg/325mg Tablet is in syrup form, measure it with a measuring cup. Your doctor will recommend how often you take Cozynil 5mg/5mg/325mg Tablet based on your medical condition. Some people may experience drowsiness, headache, tiredness, stomach upset, restlessness, and dry mouth. Most of these side effects of Cozynil 5mg/5mg/325mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Cozynil 5mg/5mg/325mg Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Cozynil 5mg/5mg/325mg Tablet. It should be used with caution in children only if prescribed by a doctor. If you have high blood pressure, kidney or liver problems, coronary artery disease (heart problems), or are receiving any monoamine oxidase inhibitor (MAO) therapy to treat depression like Isocarboxazid, Phenelzine, Selegiline, Tranylcypromine etc., inform your doctor before taking Cozynil 5mg/5mg/325mg Tablet. Do not drink alcohol with Cozynil 5mg/5mg/325mg Tablet as it may potentiate the dizziness property of Cetrizine. Hence, it is advisable not to drive or operate heavy machinery or do hazardous work, which requires mental alertness. Taking more than 4 gm per day of paracetamol can damage your liver severely, so if you have liver problems, please contact your doctor.

Uses of Cozynil 5mg/5mg/325mg Tablet

Treatment of Allergies, Common cold.

Directions for Use

• Cozynil 5mg/5mg/325mg Tablet can be taken with or without food, as advised by your doctor.• It is usually taken twice daily or as prescribed by your doctor.• Swallow Cozynil 5mg/5mg/325mg Tablet as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Cozynil 5mg/5mg/325mg Tablet is primarily used to treat common cold symptoms and reduce symptoms of allergies. It is composed of three medicines, namely Levocetirizine (antihistamine), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps shrink the blood vessels in the nostrils and the passage and reduces stuffy noses. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

How Cozynil 5mg/5mg/325mg Tablet Works

Cozynil 5mg/5mg/325mg Tablet is composed of three medicines, namely Levocetirizine (antihistamine/antiallergic), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing a stuffy nose. Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

Storage

Keep Cozynil 5mg/5mg/325mg Tablet out of the sight and reach of children.

What if I have taken an overdose of Cozynil 5mg/5mg/325mg Tablet

Do not take more than the prescribed dose of Cozynil 5mg/5mg/325mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Cozynil 5mg/5mg/325mg Tablet if you are allergic to Cozynil 5mg/5mg/325mg Tablet or any of its ingredients, are pregnant or breastfeeding before starting Cozynil 5mg/5mg/325mg Tablet. If you have high blood pressure,  kidney or liver disease, coronary artery disease, please do not take Cozynil 5mg/5mg/325mg Tablet as it is known to interact. Also, inform your doctor about all other medications you have been taking before starting Cozynil 5mg/5mg/325mg Tablet. Do not stop taking Cozynil 5mg/5mg/325mg Tablet even if you feel better without asking your doctor as your symptoms may come back and may even worsen your condition. Cozynil 5mg/5mg/325mg Tablet may cause drowsiness and sleepiness, so it is advised not to drive a car or operate machinery. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Cozynil 5mg/5mg/325mg Tablet if you have taken any MAO inhibitor (anti-depressant medication) in the past 14 days.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Cozynil 5mg/5mg/325mg Tablet:
Co-administration of Cozynil 5mg/5mg/325mg Tablet with Sevoflurane can increase the levels of Cozynil 5mg/5mg/325mg Tablet and lead to side effects.

How to manage the interaction:
Taking Cozynil 5mg/5mg/325mg Tablet with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Cozynil 5mg/5mg/325mg Tablet:
Co-administration of Selegiline with Cozynil 5mg/5mg/325mg Tablet together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Cozynil 5mg/5mg/325mg Tablet is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cozynil 5mg/5mg/325mg Tablet:
Taking Furazolidone with Cozynil 5mg/5mg/325mg Tablet can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Cozynil 5mg/5mg/325mg Tablet is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Cozynil 5mg/5mg/325mg Tablet only after 14 days of stopping Furazolidone.
How does the drug interact with Cozynil 5mg/5mg/325mg Tablet:
Taking Cozynil 5mg/5mg/325mg Tablet with Propofol may lead to increased levels of Cozynil 5mg/5mg/325mg Tablet leading to side effects like high blood pressure.

How to manage the interaction:
Taking Cozynil 5mg/5mg/325mg Tablet with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Cozynil 5mg/5mg/325mg Tablet:
Taking Tranylcypromine with Cozynil 5mg/5mg/325mg Tablet can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Cozynil 5mg/5mg/325mg Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cozynil 5mg/5mg/325mg Tablet:
Co-administration of Cozynil 5mg/5mg/325mg Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Cozynil 5mg/5mg/325mg Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Cozynil 5mg/5mg/325mg Tablet:
Co-administration of Lomitapide and Cozynil 5mg/5mg/325mg Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Cozynil 5mg/5mg/325mg Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolValdecoxib
Severe
How does the drug interact with Cozynil 5mg/5mg/325mg Tablet:
Co-administration of Cozynil 5mg/5mg/325mg Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Cozynil 5mg/5mg/325mg Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Cozynil 5mg/5mg/325mg Tablet:
Co-administration of Mipomersen with Cozynil 5mg/5mg/325mg Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Cozynil 5mg/5mg/325mg Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cozynil 5mg/5mg/325mg Tablet:
Co-administration of ketamine and Cozynil 5mg/5mg/325mg Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Cozynil 5mg/5mg/325mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.

  • Eat plenty of foods rich in good bacteria like yoghurt to improve overall health. 
  • Drink plenty of fluids to avoid dehydration.
  • Gargle with salt water for relief from sore throat.
  • Avoid alcohol consumption with Cozynil 5mg/5mg/325mg Tablet as it may cause tiredness, drowsiness, or lack of concentration.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS
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Alcohol

Unsafe

Avoid consumption of alcohol with Cozynil 5mg/5mg/325mg Tablet as it may increase drowsiness. Please consult a doctor before consuming alcohol with Cozynil 5mg/5mg/325mg Tablet.

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Pregnancy

Caution

The safety of Cozynil 5mg/5mg/325mg Tablet in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

The safety of Cozynil 5mg/5mg/325mg Tablet in breastfeeding mothers is unknown. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Cozynil 5mg/5mg/325mg Tablet may cause drowsiness or tiredness in some people. Therefore, drive only if you are alert after taking Cozynil 5mg/5mg/325mg Tablet.

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Liver

Caution

Take Cozynil 5mg/5mg/325mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Cozynil 5mg/5mg/325mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Cozynil 5mg/5mg/325mg Tablet is not recommended for children below 12 years of age. However, please consult a doctor before giving Cozynil 5mg/5mg/325mg Tablet to children.

Have a query?

FAQs

Cozynil 5mg/5mg/325mg Tablet is a cough and cold medication primarily used to treat allergies and common cold symptoms like sneezing, runny/stuffy nose, watery eyes, and itchy nose/throat.

Cozynil 5mg/5mg/325mg Tablet is composed of three medicines, namely Levocetirizine (antihistamine), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels in the nostrils and the passage and reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

No, you are not recommended to stop taking Cozynil 5mg/5mg/325mg Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Cozynil 5mg/5mg/325mg Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Cozynil 5mg/5mg/325mg Tablet, please consult your doctor.

No, you should not take Cozynil 5mg/5mg/325mg Tablet along with high blood pressure (hypertension) medication, leading to a further rise in blood pressure. Please inform your doctor if you have high blood pressure before starting Cozynil 5mg/5mg/325mg Tablet.

Yes, Cetirizine present in Cozynil 5mg/5mg/325mg Tablet may cause drowsiness. It is not necessary for everyone taking Cozynil 5mg/5mg/325mg Tablet to experience this side effect. Therefore, avoid driving and drinking alcohol if you feel drowsy after taking Cozynil 5mg/5mg/325mg Tablet.

No, you are not recommended to consume alcohol with Cozynil 5mg/5mg/325mg Tablet as it may increase drowsiness, dizziness, and lack of concentration.

No, you are not recommended to take Cozynil 5mg/5mg/325mg Tablet with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness, or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.

Common side effects of Cozynil 5mg/5mg/325mg Tablet may include headache, drowsiness, tiredness, stomach upset, restlessness, and dry mouth. In most cases, these side effects are mild and temporary, resolving on their own over time. However, if any of these side effects persist or worsen, it's essential to consult a doctor for further guidance.

Taking a higher than recommended dose of Cozynil 5mg/5mg/325mg Tablet will not increase its effectiveness; instead, it may cause serious side effects. Therefore, always follow the dose prescribed by a doctor to treat your medical condition effectively.

To ensure safe use, inform your doctor if you have any allergies or are taking other medications. It's also crucial to avoid concurrent use with St. John's Wort and MAO inhibitors. Pregnant or breastfeeding women should consult their doctor before taking this medication. Additionally, avoid consuming alcohol and only drive if you're feeling alert to minimize potential risks.

The safety of Cozynil 5mg/5mg/325mg Tablet in breastfeeding mothers is unknown. Therefore, consult a doctor if you are breastfeeding. The doctor may prescribe this medication only if the benefits outweigh the risks.

Cozynil 5mg/5mg/325mg Tablet should be stored in a cool, dry place away from sunlight. Keep it out of sight and reach of children.

Country of origin

India
Other Info - CO68546

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