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  1. Home
  2. Medicine

  3. Cresadex 20 Plus Tablet

Prescription drug
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Cresadex 20 Plus Tablet, Pack of 1
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Extra 15% Off with Bank Offers

Composition :

EZETIMIBE-10MG + ROSUVASTATIN-20MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Cresadex 20 Plus Tablet

Cresadex 20 Plus Tablet is primarily used to treat high cholesterol levels. Dyslipidaemia (high cholesterol level) is the deposition of unhealthy levels of fats (lipids) in the blood.

Cresadex 20 Plus Tablet is a combination of rosuvastatin and ezetimibe. Rosuvastatin blocks liver enzymes, causing the liver to make less cholesterol. Ezetimibe avoids the absorption of cholesterol from the intestines. Together, they provide a better decrease in cholesterol in your body.

You may experience nausea, muscle pain, weakness, joint pain, headache, abdominal pain, diarrhoea, upper respiratory tract infection, and the common cold. Most of these side effects of Cresadex 20 Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. You should contact a doctor before if you have liver or kidney problems, diabetes, severe lung disease, or musculoskeletal disorders (like myopathy and rhabdomyolysis). If you are pregnant, planning to become pregnant, or breastfeeding, then inform your doctor before taking Cresadex 20 Plus Tablet.

Uses of Cresadex 20 Plus Tablet

Cresadex 20 Plus Tablet is used in the treatment of hyperlipidemia (high cholesterol), prevention of heart attack, and prevention of stroke. The detailed uses of Cresadex 20 Plus Tablet are as follows:

  • Cholesterol Management: Cresadex 20 Plus Tablet is primarily used to lower LDL cholesterol (commonly known as 'bad' cholesterol) and triglycerides in the blood, reducing the risk of heart disease.
  • Cardiovascular Risk Reduction: By lowering cholesterol levels, Cresadex 20 Plus Tablet significantly decreases the chances of heart attacks and strokes in individuals with cardiovascular conditions or risk factors.
  • Familial Hypercholesterolemia Treatment: Cresadex 20 Plus Tablet is prescribed to manage lipid levels in patients with familial hypercholesterolemia, a genetic disorder leading to very high cholesterol levels.
  • Improving HDL Cholesterol: Cresadex 20 Plus Tablet also boosts HDL cholesterol ('good' cholesterol), promoting better heart health.

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Directions for Use

  • Take Cresadex 20 Plus Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Cresadex 20 Plus Tablet taken with dietary measures helps in the treatment of high cholesterol especially for heart patients when initial dietary measures fail to lower cholesterol.
  • Cresadex 20 Plus Tablet lowers the risk of cardiovascular disease and risk of coronary events like heart attack, stroke, and heart-related chest pain (angina).
  • Cresadex 20 Plus Tablet contains rosuvastatin, which is a lipid-lowering medicine that prevents your body from making bad cholesterol (LDL) while increasing 'good' cholesterol (HDL) levels. 
  • It blocks liver enzymes causing the liver to make less cholesterol. So, Cresadex 20 Plus Tablet increases the uptake and breakdown by the liver of cholesterol already in the blood.
  • Ezetimibe is a cholesterol absorption inhibitor that prevents the absorption of cholesterol from the intestines.
  • Together, Cresadex 20 Plus Tablet provides a better decrease in cholesterol in your body.

How Cresadex 20 Plus Tablet Works

Cresadex 20 Plus Tablet is a combination of two medicines: Rosuvastatin (HMG-CoA reductase inhibitors (statins)) and Ezetimibe (sterol absorption inhibitor). Cresadex 20 Plus Tablet contains rosuvastatin, which is a lipid-lowering medicine that prevents your body from making bad cholesterol (LDL) while increasing good cholesterol (HDL) levels. It blocks liver enzymes causing the liver to make less cholesterol. So, Cresadex 20 Plus Tablet increases the uptake and breakdown by the liver of cholesterol already in the blood. On the other hand, Ezetimibe is a cholesterol absorption inhibitor that avoids the absorption of cholesterol from the intestines. Together, they provide a better decrease in cholesterol in your body.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Cresadex 20 Plus Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Increased protein levels indicate the body is dehydrated and when blood plasma is concentrated.
  • Consume water and stay hydrated. Talk to your doctor and take an oral rehydrating salt (ORS).
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding hydration.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.

What if I have taken an overdose of Cresadex 20 Plus Tablet

Do not take more than the prescribed dose of Cresadex 20 Plus Tablet as it may cause serious side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.
  • You should contact a doctor before if you have liver or kidney problems, diabetes, severe lung disease, thyroid gland problems, or a musculoskeletal disorder (like myopathy and rhabdomyolysis).
  • It is recommended that you should have a liver enzyme test regularly if you are regularly taking Cresadex 20 Plus Tablet.
  • A person taking excessive alcohol and affected with liver disease should consult a doctor before its intake.  
  • Increase in HbA1c and fasting glucose levels can be observed if a person is regularly taking Cresadex 20 Plus Tablet. So, you should tell the doctor before having these diabetes tests.
  • If you are pregnant, planning to become pregnant, or breastfeeding, then immediately inform your doctor because Cresadex 20 Plus Tablet contains rosuvastatin that may harm an unborn baby.
  • Cresadex 20 Plus Tablet contains a sugar called lactose. If you have been told by your doctor that you have an intolerance to some sugars, talk to your doctor before taking this Cresadex 20 Plus Tablet.

Drug-Drug Interactions

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RosuvastatinGemfibrozil
Severe
RosuvastatinColchicine
Severe

Drug-Drug Interactions

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RosuvastatinGemfibrozil
Severe
How does the drug interact with Cresadex 20 Plus Tablet:
Co-administration of Gemfibrozil and Cresadex 20 Plus Tablet may increase the risk or severity of side effects like muscle injury.

How to manage the interaction:
Co-administration of Gemfibrozil and Cresadex 20 Plus Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinColchicine
Severe
How does the drug interact with Cresadex 20 Plus Tablet:
Coadministration of colchicine and Cresadex 20 Plus Tablet may increase the risk of conditions that affect your muscles and kidneys.

How to manage the interaction:
Taking Colchicine with Cresadex 20 Plus Tablet may possibly result in an interaction, but they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience abdominal discomfort, nausea, vomiting, diarrhea, back pain, weakness, or tingling or numbness in your hands and feet. Do not discontinue any medication without consulting your doctor.
RosuvastatinAmprenavir
Severe
How does the drug interact with Cresadex 20 Plus Tablet:
Co-administration of Cresadex 20 Plus Tablet and amprenavir can increase the blood levels of Cresadex 20 Plus Tablet and can increase the risk of liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Cresadex 20 Plus Tablet and Amprenavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinAtazanavir
Severe
How does the drug interact with Cresadex 20 Plus Tablet:
Co-administration of Cresadex 20 Plus Tablet and Atazanavir can increase the blood levels of Cresadex 20 Plus Tablet and can increase the risk of liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Cresadex 20 Plus Tablet and Atazanavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinLeflunomide
Severe
How does the drug interact with Cresadex 20 Plus Tablet:
Co-administration of leflunomide and Cresadex 20 Plus Tablet can increase the risk of developing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Cresadex 20 Plus Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RosuvastatinClopidogrel
Severe
How does the drug interact with Cresadex 20 Plus Tablet:
Taking Cresadex 20 Plus Tablet with clopidogrel can increase the blood levels of Cresadex 20 Plus Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although taking clopidogrel together with Cresadex 20 Plus Tablet may result in an interaction, it can be taken if prescribed by your doctor. However, consult your doctor immediately if you experience chills, joint pain or swelling, skin rash, itching, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes. Do not discontinue any medication without consulting your doctor.
RosuvastatinDarunavir
Severe
How does the drug interact with Cresadex 20 Plus Tablet:
Co-administration of Cresadex 20 Plus Tablet and Darunavir can increase the blood levels of Cresadex 20 Plus Tablet and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Cresadex 20 Plus Tablet and Darunavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinLenalidomide
Severe
How does the drug interact with Cresadex 20 Plus Tablet:
Co-administration of Cresadex 20 Plus Tablet with lenalidomide may increase the risk of a rare condition called rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Although there is an interaction between lenalidomide and Cresadex 20 Plus Tablet, it can be taken if prescribed by a doctor. However, if you experience muscle pain, tenderness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
RosuvastatinSaquinavir
Severe
How does the drug interact with Cresadex 20 Plus Tablet:
Co-administration of Saquinavir and Cresadex 20 Plus Tablet can increase the blood levels of Cresadex 20 Plus Tablet and can increase the risk of developing liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Saquinavir and Cresadex 20 Plus Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinNicotinamide
Severe
How does the drug interact with Cresadex 20 Plus Tablet:
Coadministration of Nicotinamide with Cresadex 20 Plus Tablet may increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage which can be fatal.

How to manage the interaction:
Taking Nicotinamide with Cresadex 20 Plus Tablet together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like unexplained muscle pain, muscle stiffness or tenderness, fever, dark-coloured urine, or weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with BMI 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol then only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily and if there is too much fluctuation then immediately contact your doctor.
  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help in lowering your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTILIPEMICS

Cresadex 20 Plus Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Cresadex 20 Plus Tablet to avoid unpleasant side-effects like drowsiness, dizziness, or sleepiness. It may also lead to a life-threatening condition like coma if taken with excessive alcohol.

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Pregnancy

Unsafe

Cresadex 20 Plus Tablet contains Rosuvastatin which is not recommended during pregnancy. Contact your doctor before taking Cresadex 20 Plus Tablet.

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Breast Feeding

Consult your doctor

Breastfeeding is not recommended. Contact your doctor before taking Cresadex 20 Plus Tablet.

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Driving

Caution

Cresadex 20 Plus Tablet does not usually affect your ability to drive, but sometimes cause dizziness than to contact your doctor before driving.

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Liver

Caution

Cresadex 20 Plus Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Cresadex 20 Plus Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Cresadex 20 Plus Tablet is not recommended for children as safety and efficacy of Cresadex 20 Plus Tablet has not established.

FAQs

Cresadex 20 Plus Tablet is used to treat high cholesterol levels. It lowers the risk of cardiovascular disease and risk of coronary events like heart attack, stroke, and heart-related chest pain (angina).

Usually, it is not safe to take Cresadex 20 Plus Tablet with fusidic acid as it may lead to muscle weakness, tenderness, or pain. Please consult your doctor before taking Cresadex 20 Plus Tablet along with fusidic acid.

Cresadex 20 Plus Tablet works by preventing your body from making bad cholesterol (LDL) while increasing good cholesterol (HDL) levels. It increases the uptake and breakdown of cholesterol already in the blood by the liver.

No, Cresadex 20 Plus Tablet should not be stopped even if you feel better as it leads to worsening of your condition. Please consult your doctor if you feel better and do as advised.

Yes, Cresadex 20 Plus Tablet can be taken at night or any other time with or without food. It is better to take it at a fixed time.

Increase your daily diet with fiber, fruits, vegetables, whole grains, and fish, and cut saturated fat as well. Stop smoking and drinking and try to work out every day as well.

Country of origin

India

Manufacturer/Marketer address

Office no 61, SCO-2, Motia Plaza,Baddi, Distt. Solan-173205
Other Info - CR63447

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 18, 2025 | 1:08 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.8866.pdf
  2. https://www.medicines.org.uk/emc/files/pil.8618.pdf
  3. https://www.drugs.com/ezetimibe.html
  4. https://www.drugs.com/mtm/rosuvastatin.html
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