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  3. CUBICIN 350MG INJECTION

CUBICIN 350MG INJECTION, Pack of 1 INJECTION
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Composition :

DAPTOMYCIN-350MG

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About CUBICIN 350MG INJECTION

CUBICIN 350MG INJECTION is an antibiotic used to treat bacterial infections. It is used to treat complicated skin and skin structure infections and blood infections such as bacteremia (presence of bacteria in the bloodstream) and right-sided infective endocarditis (inflammation/swelling of the inner lining of the heart due to the presence of bacteria). A bacterial infection occurs when harmful bacteria enter the body, multiply and cause infection. It can infect any part of the body and multiply very quickly. CUBICIN 350MG INJECTION is only effective in treating infections caused by bacteria and not effective for viral infections like flu or a common cold.

CUBICIN 350MG INJECTION contains Daptomycin, which belongs to the cyclic lipopeptide class of antibiotics. It works against various types of bacteria. This medicine works by inhibiting the process of bacterial cell wall synthesis that is required for its survival. Thus, CUBICIN 350MG INJECTION kills bacteria and prevents the growth of bacterial infection. 

CUBICIN 350MG INJECTION may cause certain common side effects such as injection site reactions, rash, vomiting, allergic reaction, chest pain, hypotension, increased sweating, difficulty sleeping, dizziness, sore throat, nausea, and diarrhoea. Most of these side effects are mild and subside over time. However, if these persist, contact your doctor immediately. This medicine is a parenteral formulation. A qualified healthcare doctor will administer it. Hence, do not self-administer.

CUBICIN 350MG INJECTION should be avoided if you are allergic to it or other antibiotics. CUBICIN 350MG INJECTION should be used with caution if you have liver problems, kidney disease, myasthenia gravis, myopathy, rhabdomyolysis, eosinophilic pneumonia, peripheral neuropathy, heart rhythm disorder (arrhythmia), or electrolyte imbalance (low potassium or magnesium level). Inform your doctor if you have/had diarrhoea for more than four days. However, do not take any anti-diarrheal medicine until your doctor tells you. Birth control pills may not work effectively while using this medication. So, speak to your doctor about using non-hormonal birth control to avoid pregnancy. If you are pregnant or breastfeeding, inform your doctor before receiving CUBICIN 350MG INJECTION. This medicine is not recommended for use in children below 12 years of age as the safety and efficacy are not established.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• CUBICIN 350MG INJECTION will be administered in the hospital setting by a trained healthcare professional.• Do not self-administer.

Medicinal Benefits

CUBICIN 350MG INJECTION is a broad-spectrum antibiotic that is effective against a wide range of bacterial infections. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. CUBICIN 350MG INJECTION contains Daptomycin, which belongs to the cyclic lipopeptide class of antibiotics. It works against various types of bacteria. This medicine works by inhibiting the process of bacterial cell wall synthesis that is required for its survival. Thus, CUBICIN 350MG INJECTION kills bacteria and prevents the growth of bacterial infection.

How CUBICIN 350MG INJECTION Works

CUBICIN 350MG INJECTION contains Daptomycin, which belongs to the cyclic lipopeptide class of antibiotics. It works against various types of bacteria. This medicine works by inhibiting the process of bacterial cell wall synthesis that is required for its survival. Thus, CUBICIN 350MG INJECTION kills bacteria and prevents the growth of bacterial infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Cubicin 350mg Injection
  • Eat fatty fish rich in omega-3 fatty acids to reduce inflammation.
  • Add whole grains such as brown rice, quinoa, and whole wheat bread to your diet for a nutritional boost.
  • Add nuts and seeds like almonds, walnuts, chia seeds for anti-inflammatory benefits.
  • Eat dark leafy greens like spinach, kale, collard greens for antioxidants.
  • Include berries like blueberries, strawberries, raspberries for anti-inflammatory properties.
  • Rest and take a break from usual activities.
  • Apply ice for 15-20 minutes, 3 times a day to reduce pain and inflammation.
  • Use compression with a stretchable bandage or wrap to lessen swelling and provide support.
  • Avoid strenuous activities and rest the affected area.
  • Try light stretching with gentle exercises to maintain flexibility.
  • Consider OTC pain medications like ibuprofen or acetaminophen but consult a doctor before taking any medication.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

What if I have taken an overdose of CUBICIN 350MG INJECTION

As CUBICIN 350MG INJECTION is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Avoid receiving CUBICIN 350MG INJECTION if you are allergic to it or other antibiotics. CUBICIN 350MG INJECTION should be used with caution if you have liver problems, kidney disease, myasthenia gravis, myopathy, rhabdomyolysis, eosinophilic pneumonia, peripheral neuropathy, heart rhythm disorder (arrhythmia), or electrolyte imbalance (low potassium or magnesium level). Inform your doctor if you have/had diarrhoea for more than four days. However, do not take any anti-diarrheal medicine until your doctor tells you. CUBICIN 350MG INJECTION is ineffective for treating pneumonia and left-sided infective endocarditis. Birth control pills may not work effectively while using this medication. So, speak to your doctor about using non-hormonal birth control to avoid pregnancy. If you are pregnant or breastfeeding, inform your doctor before receiving CUBICIN 350MG INJECTION. This medicine is not recommended for use in children below 12 years of age as the safety and efficacy is not established.

Drug-Drug Interactions

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DaptomycinBCG vaccine
Severe
DaptomycinCholera, live attenuated
Severe

Drug-Drug Interactions

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DaptomycinBCG vaccine
Severe
How does the drug interact with Cubicin 350mg Injection:
Combining Cubicin 350mg Injection with BCG vaccine may reduce the activity of the BCG vaccine.

How to manage the interaction:
Although there is a possible interaction between Cubicin 350mg Injection and BCG vaccine, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual side effects, contact a doctor. Do not stop using any medications without first consulting a doctor.
DaptomycinCholera, live attenuated
Severe
How does the drug interact with Cubicin 350mg Injection:
Combining Cubicin 350mg Injection with Cholera, live attenuated vaccine may reduce the activity of the Cholera, live attenuated vaccine.

How to manage the interaction:
Although there is a possible interaction between Cubicin 350mg Injection and Cholera, live attenuated vaccine, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual side effects, contact a doctor. Let your doctor know about the antibiotic course you used since 14 days before taking the vaccine. Do not stop using any medications without first consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Diarrhea may happen as a side effect. Taking probiotics after receiving CUBICIN 350MG INJECTION may help. Talk to your doctor if you notice blood stools or develop stomach cramps.
  • Drink plenty of fluids to avoid an upset stomach and hydrate your body.
  • Avoid intake of alcoholic beverages with CUBICIN 350MG INJECTION as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the CUBICIN 350MG INJECTION in fighting off infections.
  • Maintain good hygiene and avoid contaminated or processed food.
  • Include more fibre-enriched food like whole-grain bread and brown rice in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. 
  • Avoid taking too much calcium-enriched foods and drinks as it might affect the working of CUBICIN 350MG INJECTION.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

CUBICIN 350MG INJECTION Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while receiving treatment with CUBICIN 350MG INJECTION as it may worsen your condition.

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Pregnancy

Caution

Limited data are available for the use of CUBICIN 350MG INJECTION in pregnancy. Hence, this medicine should not be used in pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or planning a pregnancy before receiving CUBICIN 350MG INJECTION.

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Breast Feeding

Caution

Limited data are available for the use of CUBICIN 350MG INJECTION in breastfeeding. Hence, this medicine should not be used in breastfeeding mothers unless clearly necessary. So, inform your doctor if you are breastfeeding your child before receiving CUBICIN 350MG INJECTION.

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Driving

Unsafe

Avoid driving vehicles or operating machines as CUBICIN 350MG INJECTION causes dizziness and makes you feel sleepy or dizzy.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving CUBICIN 350MG INJECTION. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

CUBICIN 350MG INJECTION should be used under caution in patients with kidney disease. Inform your doctor if you have kidney problems. Your doctor will prescribe only if the benefits outweigh the risks. If prescribed, your doctor may adjust the dose based on your health condition.

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Children

Unsafe

CUBICIN 350MG INJECTION is not recommended for use in children below 12 years of age as the safety and efficacy is not established

Have a query?

FAQs

CUBICIN 350MG INJECTION is used to treat Bacterial infections.

CUBICIN 350MG INJECTION contains daptomycin, an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria.

Do not use anti-diarrhoeal medication until the doctor has prescribed you. You can drink plenty of fluids (electrolytes) to avoid dehydration. Besides this, you can also take prebiotics or probiotics to manage diarrhea as it may help in increasing the number of good bacteria in the intestine, which aids in digestion.

No, CUBICIN 350MG INJECTION is not used to treat lung infections such as pneumonia caused by bacteria.

CUBICIN 350MG INJECTION does not work against viral infection. So, it should not be taken to treat the common cold or cough. Consult your doctor if you have these symptoms.

As CUBICIN 350MG INJECTION is injectable, it can start working soon after administration. However, CUBICIN 350MG INJECTION may take a few days to kill the bacteria and prevent further spread of infection.

CUBICIN 350MG INJECTION belongs to the cyclic lipopeptide class of antibiotics. It targets various types of bacteria by treating bacterial infections, including complicated skin and skin structure infections, blood infections such as bacteraemia (bacteria in the bloodstream), and right-sided infective endocarditis (inflammation of the inner lining of the heart caused by bacteria). The medication works by inhibiting bacterial cell wall synthesis, a process essential for bacterial survival. This action effectively kills bacteria and prevents the spread of the infection.

CUBICIN 350MG INJECTION should be administered by the doctor or nurse through an intravenous route (into the vein) over 2 minutes. Do not self-administer.

CUBICIN 350MG INJECTION is generally considered safe when used as prescribed by a doctor and do not skip the schedule of receiving CUBICIN 350MG INJECTION. However, it may cause side effects in some individuals, so consult the doctor for personalized advice.

The side effects of CUBICIN 350MG INJECTION include rash, injection site reactions, vomiting, allergic reaction, chest pain, hypotension, increased sweating, difficulty sleeping, dizziness, sore throat, nausea, and diarrhoea. Most of these side effects are mild and typically go away on their own over time. However, if any symptoms persist or worsen, consult the doctor immediately.

If you experience dizziness while taking CUBICIN 350MG INJECTION, lie down for a while and then get up slowly. Moving cautiously can also help manage dizziness. Avoid coffee, cigarettes, and alcohol. Consult the doctor, if the dizziness persists or worsens.

Country of origin

United Kingdom

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - CUB0001

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 17, 2025 | 10:56 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/208385s005lbl.pdf
  2. https://www.ncbi.nlm.nih.gov/books/NBK470407/
  3. https://go.drugbank.com/drugs/DB00080
  4. https://reference.medscape.com/drug/cubicin-daptomycin-342576
  5. https://medlineplus.gov/druginfo/meds/a608045.html

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