Cyclocel 1000 mg Injection 1's

Prescription drug

MRP ₹125

(Inclusive of all Taxes)

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Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cyclocel 1000 mg Injection 1's is used to treat Cancer. It contains 'Cyclophosphamide' that works by stopping or slowing the growth of cancer cells in the body. Thereby, It helps treat Cancer. Additionally, It is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients. It suppresses the body's immune system, thereby helping treat nephrotic syndrome. Common side effects of Cyclocel 1000 mg Injection 1's are nausea, vomiting, stomatitis (inflamed and sore mouth), weakness, malaise (general discomfort), fever, leukopenia (low white blood cell count), and alopecia (hair loss).

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About Cyclocel 1000 mg Injection 1's

Cyclocel 1000 mg Injection 1's belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma, Burkitt's lymphoma, leukaemia, neuroblastoma, retinoblastoma, adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma, small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. Additionally, Cyclocel 1000 mg Injection 1's is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients.

Cyclocel 1000 mg Injection 1's contains 'Cyclophosphamide' that works by stopping or slowing the growth of cancer cells in the body. Thereby, Cyclocel 1000 mg Injection 1's helps treat cancer. Cyclocel 1000 mg Injection 1's suppresses the body's immune system and helps treat nephrotic syndrome.

In some cases, Cyclocel 1000 mg Injection 1's may cause nausea, vomiting, stomatitis (inflamed and sore mouth), weakness, malaise (general discomfort), fever, leukopenia (low white blood cell count), and alopecia (hair loss). You are advised to talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding. Cyclocel 1000 mg Injection 1's may cause dizziness, so drive only if you are alert. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Cyclocel 1000 mg Injection 1's

Cyclocel 1000 mg Injection 1's is used in the treatment of Cancer and nephrotic syndrome (kidney disease). The detailed uses of Cyclocel 1000 mg Injection 1's are as follows:

Treat various types of cancer: Cyclocel 1000 mg Injection 1's is a chemotherapy drug used to manage cancers such as breast cancer, ovarian cancer, leukemia, lymphoma (including Hodgkin’s and non-Hodgkin’s), multiple myeloma, and brain tumours by damaging the DNA of cancer cells and stopping their growth.
Manage autoimmune and kidney disorders: Cyclocel 1000 mg Injection 1's is also used in conditions like nephrotic syndrome and systemic lupus erythematosus, especially when other treatments have failed.

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Directions for Use

Your doctor will determine the dosage and frequency depending on your condition.
Cyclocel 1000 mg Injection 1's will be administered by a healthcare professional.
Do not self-administer.

Medicinal Benefits

Cyclocel 1000 mg Injection 1's belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease (cancer of the lymphatic system), mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma (cancer of plasma cells), Burkitt's lymphoma, leukaemia (blood cancer), neuroblastoma (cancer commonly found in the adrenal glands), retinoblastoma (eye cancer), adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma (cancer in and around the bones), small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. Cyclocel 1000 mg Injection 1's works by stopping or slowing the growth of cancer cells in the body. Thereby, Cyclocel 1000 mg Injection 1's helps treat cancer. Additionally, Cyclocel 1000 mg Injection 1's is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients. Cyclocel 1000 mg Injection 1's suppresses the body's immune system, thereby helping treat nephrotic syndrome.

How Cyclocel 1000 mg Injection 1's Works

Cyclocel 1000 mg Injection 1's contains 'Cyclophosphamide' that works by stopping or slowing the growth of cancer cells in the body. Thereby, Cyclocel 1000 mg Injection 1's helps treat cancer. Cyclocel 1000 mg Injection 1's suppresses the body's immune system and helps treat nephrotic syndrome.

Storage

• Store in a cool and dry place away from sunlight.• Keep Cyclocel 1000 mg Injection 1's out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Side effects of Cyclocel 1000 mg Injection

Decreased Production Of Blood Cells

Eat well-cooked food to minimize infection risk.
Practice good hand hygiene to prevent infections.
Avoid crowds and people with illnesses to reduce exposure.
Wear a mask when necessary to lower infection risk.
Rest adequately to support your body's healing process.
Stay hydrated by drinking plenty of water.
Regularly monitor blood cell counts for changes.
Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
Consult your doctor right away if concerning symptoms arise.
Follow your doctor's guidance on managing myelosuppression and infection prevention.

Haemolytic uraemic syndrome (Kidney Disorder)

Weakened Immune System

Your doctor may adjust the dose of the suspected medication based on your immune health; however, do not stop taking it suddenly without consulting them first.
Wash your hands often and handle food safely to avoid germs.
Get enough sleep and manage your stress levels to help your immune system stay strong.
Eat a balanced diet with plenty of vegetables, fruits, whole grains, dairy, and proteins.
Do not eat raw eggs, meat, fruits, unpasteurized milk, or uncooked vegetables.
Stay away from crowded places and individuals who are sick.
Have regular blood tests to check your immune system’s health.
Keep your vaccines up-to-date and ask your doctor about which vaccines you need.

Hair Loss

Eat protein-rich foods like fish, poultry, eggs, and legumes.
Include foods with minerals and vitamins essential for hair health.
Join a support group to connect with others experiencing hair loss.
Openly discuss your feelings about hair loss.
Consider covering up with wigs, hats, or scarves.
Be patient and avoid seeking miracle cures.

Bladder Infection

Bladder infection needs immediate medical attention when you observe blood in urine or have any abnormal changes in your body.
Get a physical examination and blood tests to identify factors that led to infection and initiate the treatment process immediately.
Avoid anxiety and stress, as it can worsen your condition.
Follow your doctor's instructions, and there can be medication with antibiotics and other supportive vitamins.
Take a balanced diet to prevent negative changes in your body.

Small Amounts Of Blood In Urine

Stay hydrated to support kidney and bladder health.
Rest on your back as advised by your doctor.
Limit physical strain for 1-2 weeks.
Avoid strenuous activities like running and contact sports.
Quit smoking to improve overall health.
Use pain medication responsibly.
Avoid foods that can irritate the urinary track, such as spicy or acidic foods.
Remember to consult your doctor for personalized advice and guidance on managing your symptoms and developing a treatment plan.

High Body Temperature

Here's a comprehensive approach to managing medication-triggered fever:

Inform your doctor immediately if you experience a fever after starting a new medication.
Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
Monitor your body temperature to monitor fever progression.
Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

What if I have taken an overdose of Cyclocel 1000 mg Injection 1's

As Cyclocel 1000 mg Injection 1's is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not take Cyclocel 1000 mg Injection 1's if you are allergic to any of its components. Inform your doctor if you have acute infections, bone marrow depression, urinary tract infections, urinary outflow/obstruction, liver or kidney problems, or urinary or respiratory symptoms. Consult your doctor if you are pregnant or breastfeeding. Cyclocel 1000 mg Injection 1's may cause myelosuppression, immunosuppression, bone marrow failure, and infections; consult your doctor if you have any concerns.

Drug-Drug Interactions

CyclophosphamideNalidixic acid

Critical

CyclophosphamideCidofovir

Critical

Drug-Drug Interactions

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CyclophosphamideNalidixic acid

Critical

How does the drug interact with Cyclocel 1000 mg Injection:
Co-administration of Nalidixic acid with Cyclocel 1000 mg Injection may cause an increase in the risk of side effects.

How to manage the interaction:
Co-administration of Cyclocel 1000 mg Injection and Nalidixic acid can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like bruising or bleeding, unusual weakness, nausea, stomach pain, low fever, or loss of appetite, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

CyclophosphamideCidofovir

Critical

How does the drug interact with Cyclocel 1000 mg Injection:
Co-administration of Cyclocel 1000 mg Injection and Cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Taking Cyclophosphamine with Cidofovir is not recommended, please consult your doctor before taking it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor

CyclophosphamideAdalimumab

Severe

How does the drug interact with Cyclocel 1000 mg Injection:
When Adalimumab is taken with Cyclocel 1000 mg Injection, may increase the risk of serious infections.

How to manage the interaction:
Although taking Cyclocel 1000 mg Injection and Adalimumab together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.

CyclophosphamideLevobupivacaine

Severe

How does the drug interact with Cyclocel 1000 mg Injection:
Co-administration of Cyclocel 1000 mg Injection with Levobupivacaine can increase the risk of methemoglobinemia (low level of oxygen in the blood).

How to manage the interaction:
Co-administration of Levobupivacaine with Cyclocel 1000 mg Injection can possibly result in an interaction, but it can be taken if a doctor has advised it. Keep a close eye on any signs or symptoms of Methemoglobinemia. If you notice any of these symptoms like gray skin, feeling sick, headaches, dizziness, tiredness, or trouble breathing, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.

CyclophosphamideLeflunomide

Severe

How does the drug interact with Cyclocel 1000 mg Injection:
Taking Cyclocel 1000 mg Injection with Leflunomide may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Cyclocel 1000 mg Injection can be taken with Leflunomide if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.

CyclophosphamideTofacitinib

Severe

How does the drug interact with Cyclocel 1000 mg Injection:
Taking Cyclocel 1000 mg Injection with Tofacitinib may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Cyclocel 1000 mg Injection can be taken with Tofacitinib if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.

CyclophosphamideGolimumab

Severe

How does the drug interact with Cyclocel 1000 mg Injection:
Co-administration of Golimumab with Cyclocel 1000 mg Injection may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Cyclocel 1000 mg Injection with Golimumab can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination. Do not stop using any medications without a doctor's advice.

CyclophosphamideThiotepa

Severe

How does the drug interact with Cyclocel 1000 mg Injection:
When Thiotepa is taken with Cyclocel 1000 mg Injection, can increase the blood levels or add to the medication side effects of Cyclocel 1000 mg Injection.

How to manage the interaction:
Although taking Thiotepa and Cyclocel 1000 mg Injection together can evidently cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.

CyclophosphamideTenofovir alafenamide

Severe

How does the drug interact with Cyclocel 1000 mg Injection:
Co-administration of Tenofovir alafenamide may cause kidney problems, and combining it with Cyclocel 1000 mg Injection may increase the risk.

How to manage the interaction:
Although there is a possible interaction, Cyclocel 1000 mg Injection can be taken with Tenofovir alafenamide if prescribed by the doctor. Consult the doctor if you develop signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop any medication without consulting a doctor.

CyclophosphamideVoclosporin

Severe

How does the drug interact with Cyclocel 1000 mg Injection:
Co-administration of Cyclocel 1000 mg Injection with Voclosporin can increase the risk of kidney damage.

How to manage the interaction:
Although there is a possible interaction between Cyclocel 1000 mg Injection and Voclosporin, you can take these medicines together if prescribed by a doctor. It's important to keep an eye on how much you pee. Some other signs to watch out for are feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, holding onto fluids, having a fever or chills, having diarrhea or a sore throat, feeling weak or dizzy, being confused, having trouble breathing, feeling pain or a burning sensation when you pee, or having an irregular heartbeat. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Eat a healthy diet and exercise regularly to maintain proper weight.
Avoid smoking and alcohol consumption.
Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your food.
Avoid fast food, fried food, processed meats, refined carbs and added sugar.
Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

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Alcohol

Caution

You are recommended to avoid alcohol consumption as it may worsen the risk of cyclophosphamide-induced nausea and vomiting.

Pregnancy

Caution

It is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Cyclocel 1000 mg Injection 1's. Your doctor may prescribe this medicine only if the benefits outweigh the risks.

Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Cyclocel 1000 mg Injection 1's. Avoid breastfeeding during treatment with Cyclocel 1000 mg Injection 1's and for one week after the last dose.

Driving

Caution

Cyclocel 1000 mg Injection 1's may cause dizziness. Do not drive or operate heavy machinery until you are alert.

Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Cyclocel 1000 mg Injection 1's. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

Kidney

Caution

If you have a history of kidney diseases, inform your doctor before receiving Cyclocel 1000 mg Injection 1's. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

Children

Consult your doctor

Please consult your doctor. Your doctor will with the benefits and risks before prescribing this medicine based on your child's medical condition.

Heart

Please inform your doctor before taking this medicine if you have a heart problem or any concerns regarding this.

Geriatrics

Caution

Cyclocel 1000 mg Injection 1's should be used in the elderly only if advised by a doctor, as dose adjustment may be required.

FAQs

What is the use of Cyclocel 1000 mg Injection 1's?

Cyclocel 1000 mg Injection 1's is used to treat Cancer and nephrotic syndrome (kidney disease).

How does Cyclocel 1000 mg Injection 1's work?

Cyclocel 1000 mg Injection 1's works by stopping or slowing down the growth of cancer cells in the body. Thereby, Cyclocel 1000 mg Injection 1's helps treat cancer. Cyclocel 1000 mg Injection 1's suppresses the body's immune system and helps treat nephrotic syndrome.

Does Cyclocel 1000 mg Injection 1's cause infertility?

Cyclocel 1000 mg Injection 1's might impair fertility and interfere with oogenesis (development of ovum) and spermatogenesis (development of sperm). Please consult your doctor if you have any concerns.

Is it safe to father a child while on treatment with Cyclocel 1000 mg Injection 1's?

Men should avoid fathering a child during the treatment and for six months following discontinuation of therapy.

Does Cyclocel 1000 mg Injection 1's interfere with wound healing?

Cyclocel 1000 mg Injection 1's might interfere with normal wound healing. Therefore, be cautious while handling sharp objects. Consult your doctor if you notice unusual bleeding or bruising or if the wounds do not heal properly.

Country of origin

India

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081

Other Info - CYC0076

Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Oct 14, 2025 | 1:04 PM IST

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