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  3. Cycloglob 25mg Tablet

Cycloglob 25mg Tablet, Pack of 1 Tablet
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cycloglob 25mg Tablet is used to treat cancer and nephrotic syndrome (kidney disease). It contains Cyclophosphamide that stops the growth and multiplication of cancer cells. In some cases, this medicine may cause side effects such as fever, nausea, vomiting, diarrhoea, hair loss, low blood cell count, and abdominal pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

CYCLOPHOSPHAMIDE-25MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Cycloglob 25mg Tablet

Cycloglob 25mg Tablet is used to treat malignant diseases such as lymphoma (Hodgkin’s disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma, Burkitt’s lymphoma, mycosis fungoide), leukaemia,  nerve tissue cancer, eye cancer, ovarian cancer, soft tissue cancer, bone cancer, and breast cancer. Additionally, Cycloglob 25mg Tablet is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients.
 
Cycloglob 25mg Tablet contains ‘Cyclophosphamide’, an alkylating agent that damages the genetic material of cancer cells to stop their growth and multiplication. Thus, Cycloglob 25mg Tablet helps treat cancer by killing the cancer cells.
 
You are advised to take Cycloglob 25mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as fever, nausea, vomiting, diarrhoea, hair loss, low blood cell count, and abdominal pain. Do not be reluctant to talk with your doctor if you experience any of these side effects persistently.
 
Do not take Cycloglob 25mg Tablet if you are allergic to any of its components; or if you have bladder obstruction or other urination problems. Avoid taking Cycloglob 25mg Tablet if you are pregnant or breastfeeding. Cycloglob 25mg Tablet may cause dizziness, so drive only if you are alert. Cycloglob 25mg Tablet should be given to children only if prescribed by the doctor. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Cycloglob 25mg Tablet

Cycloglob 25mg Tablet is used for the treatment of cancer and nephrotic syndrome (kidney disease). The detailed uses of Cycloglob 25mg Tablet are as follows:

  • Cancer treatment: Cycloglob 25mg Tablet is used to treat various cancers, including lymphomas, leukaemia, and breast cancer, by slowing or stopping cancer cell growth.
  • Autoimmune disorders: Cycloglob 25mg Tablet helps manage autoimmune diseases like lupus and rheumatoid arthritis by suppressing the immune response and reducing inflammation.
  • Organ Transplantation: Cycloglob 25mg Tablet is used in organ transplant patients to prevent rejection by suppressing the immune system.
  • Nephrotic Syndrome: Cycloglob 25mg Tablet is used to treat nephrotic syndrome, especially in cases resistant to standard treatments, by reducing proteinuria and improving kidney function.
  • Scleroderma Treatment: Cycloglob 25mg Tablet is involved in managing scleroderma by alleviating symptoms and slowing disease progression through immune system suppression.

Directions for Use

• It is generally recommended to take Cycloglob 25mg Tablet with food to prevent stomach upset or as advised by the doctor. • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety. • Swallow Cycloglob 25mg Tablet as a whole with a glass of water. • Do not chew, crush or break it.

Medicinal Benefits

Cycloglob 25mg Tablet belongs to the group of anti-cancer medicines used to treat malignant diseases such as Hodgkin’s disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma(cancer of plasma cells), Burkitt’s lymphoma, leukaemia (blood cancer), neuroblastoma (nerve tissue cancer), retinoblastoma (eye cancer), adenocarcinoma of the ovary (ovarian cancer), mycosis fungoides (T-cell lymphoma), rhabdomyosarcoma (soft tissue cancer), osteosarcoma (bone cancer), and breast carcinoma. Additionally, Cycloglob 25mg Tablet is used to treat minimal change nephrotic syndrome (kidney disease) in pediatric patients. Cycloglob 25mg Tablet is an alkylating agent that stops the growth and multiplication of cancer cells by damaging their genetic material. Thereby, Cycloglob 25mg Tablet helps to treat cancer by killing the cancer cells.

How Cycloglob 25mg Tablet Works

Cycloglob 25mg Tablet contains ‘Cyclophosphamide’, an alkylating agent that damages the genetic material of cancer cells to stop their growth and multiplication. Thus, Cycloglob 25mg Tablet helps treat cancer by killing the cancer cells.

Storage

• Store in a cool and dry place away from sunlight.• Keep Cycloglob 25mg Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Cycloglob 25mg Tablet

Take Cycloglob 25mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include black/tarry stools, red urine, unusual bleeding/bruising, unusual tiredness/weakness, signs of infection (sore throat, cough, fever), chest pain, and swelling in the ankles, feet or legs. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Cycloglob 25mg Tablet if you are allergic to any of its contents; or have urinary flow obstruction, bone marrow suppression, or infections. Talk to your doctor if you have myelosuppression, immunosuppression, infections, diabetes, heart, lung, liver, or kidney problems. Inform your doctor if you are receiving any radiotherapy or chemotherapy. Avoid taking Cycloglob 25mg Tablet if you are pregnant or breastfeeding. Cycloglob 25mg Tablet may cause dizziness, so drive only if you are alert. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Diet & Lifestyle Advise

  • Consume a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.
  • Stay protected from the sun. Avoid tanning beds and cover up with clothing, sunscreen, and sunglasses.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY
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Alcohol

Consult your doctor

It is not known if alcohol affects Cycloglob 25mg Tablet. Please consult your doctor.

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Pregnancy

Unsafe

Cyclophosphamide belongs to pregnancy category D. Cycloglob 25mg Tablet should not be taken during pregnancy as it might cause fetal harm. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnant.

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Breast Feeding

Unsafe

Cycloglob 25mg Tablet passes into breastmilk. Avoid breastfeeding while taking Cycloglob 25mg Tablet.

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Driving

Caution

Cycloglob 25mg Tablet may cause dizziness. Drive or operate heavy machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Cycloglob 25mg Tablet should be used with caution in patients with renal impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Cycloglob 25mg Tablet should be given to children only if prescribed by a doctor.

Have a query?

FAQs

Cycloglob 25mg Tablet is used to treat malignant diseases such as lymphoma (Hodgkin’s disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma, Burkitt’s lymphoma, mycosis fungoide), leukaemia, nerve tissue cancer, eye cancer, ovarian cancer, soft tissue cancer, bone cancer, and breast cancer. Additionally, Cycloglob 25mg Tablet is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients.

Cycloglob 25mg Tablet is an alkylating agent that stops the growth and multiplication of cancer cells by damaging their genetic material. Thereby, Cycloglob 25mg Tablet helps to treat cancer by killing the cancer cells.

Do not stop taking Cycloglob 25mg Tablet on your own. You are advised to take Cycloglob 25mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Cycloglob 25mg Tablet.

Cycloglob 25mg Tablet might interfere with oogenesis (development of ovum) and spermatogenesis (development of sperm) and could impair fertility. Before starting treatment with Cycloglob 25mg Tablet, talk to your doctor regarding cryopreservation/freezing of eggs/sperm if you consider becoming parents.

Cycloglob 25mg Tablet might interfere with normal wound healing. Therefore, be cautious while handling sharp objects. Consult your doctor if you notice unusual bleeding, or bruising or if the wounds do not heal properly.

No, it is not safe to father a child while taking Cycloglob 25mg Tablet. Use effective contraception while taking Cycloglob 25mg Tablet and for at least four months after treatment. Women of childbearing age taking Cycloglob 25mg Tablet should use highly effective contraceptives while taking Cycloglob 25mg Tablet up to 1 year after the treatment.

Cycloglob 25mg Tablet might cause myelosuppression/bone marrow suppression leading to a decrease in white blood cells. This could lead to an increased risk of infections. Regular blood tests while taking Cycloglob 25mg Tablet are advised.

During treatment with Cycloglob 25mg Tablet, stay protected from sun and avoid excessive sun exposure. It’s best to use sunscreen, sunglasses and protective clothing to prevent skin damage, if your immune system is weakened.

Cancer treatments like chemotherapy and radiation therapy can increase the chance of developing other cancers, which may appear years after treatment with Cycloglob 25mg Tablet. The use of Cycloglob 25mg Tablet is associated with a higher risk of bladder cancer. Rarely, it may also increase the risk of other cancers like acute leukaemia, and ureter cancer.

Cycloglob 25mg Tablet is a chemotherapy medicine which belongs to the class of alkylating agents. It works by destroying cancer cells.

Yes, Cycloglob 25mg Tablet may be used to treat nephrotic syndrome in children, especially in cases where the condition has not improved, or has recurred after using other medications. It is also an option for children who have experienced severe side effects from other treatments. However, its safety and effectiveness for nephrotic syndrome in adults have not been established.

Cycloglob 25mg Tablet may cause weight loss due to decreased appetite and may be due to underlying cancer. Consult a doctor if you experience significant weight loss.

Cycloglob 25mg Tablet may cause side effects such as fever, nausea, vomiting, diarrhoea, hair loss, low blood cell count, and abdominal pain. However, if these side effects persist or worsen, please consult your doctor.

Country of origin

India
Other Info - CY26212

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 6, 2025 | 10:26 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf
  2. https://www.medicines.org.uk/emc/medicine/30161#gref
  3. https://www.drugs.com/mtm/cyclophosphamide-oral-and-injection.html
  4. https://mri.cts-mrp.eu/human/downloads/NL_H_2814_002_FinalPL.pdf
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