Dacoplice 45mg Tablet 30's

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Written By Lakshmithulasi Yarragunta ,

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dacoplice 45mg Tablet is an anti-cancer medicine used to treat non-small cell lung cancer (NSCLC). It consists of Dacominitib, which belongs to the class of medicines known as kinase inhibitors. It works by stopping the action of an enzyme (tyrosine kinase) that causes the multiplication of cancerous cells; this prevents the abnormal growth of cancer cells and thus reduces the spread of cancer to other parts of the body.

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About Dacoplice 45mg Tablet

Dacoplice 45mg Tablet is an anti-cancer medicine used in the treatment of non-small cell lung cancer (NSCLC). It is a common form of lung cancer in which abnormal cells grow in the lung tissues. Dacoplice 45mg Tablet is used as a first-line therapy in the treatment of metastatic NSCLC with epidermal growth factor receptor (EGFR) exon 19 deletion or exon 21 L858R substitution mutations.

Dacoplice 45mg Tablet consists of Dacominitib, which belongs to the class of medicines known as kinase inhibitors. It works by stopping the action of an enzyme (tyrosine kinase) that causes the multiplication of cancerous cells. This prevents the abnormal growth of cancer cells and thus reduces the further spread to other parts of the body.

Dacoplice 45mg Tablet may cause certain side effects such as diarrhea, rash, nausea, vomiting, dry skin, mouth sores, nail inflammation, ache, cough, abdominal pain, hair loss, decreased appetite, decreased weight loss, and itching. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Dacoplice 45mg Tablet should be taken as advised by your doctor. Do not take more than the recommended dose. Your doctor will decide the dose of Dacoplice 45mg Tablet based on the severity of your condition.

Avoid taking Dacoplice 45mg Tablet if you are allergic to it or any other components of it. Before taking Dacoplice 45mg Tablet , inform your doctor if you have/had liver or kidney disease and lung disease other than lung cancer. This medicine is known to cause embryo-fetal toxicity. It is not recommended for use in pregnancy and breastfeeding. Elderly people are more sensitive to medicine, so the dose may have to be adjusted according to their condition.

Uses of Dacoplice 45mg Tablet

Dacoplice 45mg Tablet is used in the treatment of Non-small cell lung cancer (NSCLC). The detailed use of Dacoplice 45mg Tablet is as follows:

Advanced or Metastatic NSCLC: Dacoplice 45mg Tablet is used in the treatment of Non-small cell lung cancer (NSCLC).

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Directions for Use

Dacoplice 45mg Tablet can be taken with or without food as advised by your doctor.
It is recommended to take Dacoplice 45mg Tablet once daily or as advised by your doctor.
Swallow Dacoplice 45mg Tablet as a whole with a full glass of water.
Do not chew, crush, or break it.

Medicinal Benefits

Dacoplice 45mg Tablet contains Dacominitib, which belongs to the class of medicines known as kinase inhibitors. It works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. In this way, Dacoplice 45mg Tablet stops the body's production, spread and growth of cancerous cells.

How Dacoplice 45mg Tablet Works

Dacoplice 45mg Tablet consists of Dacominitib, which belongs to the class of medicines known as kinase inhibitors. It works by stopping the action of an enzyme (tyrosine kinase) that causes the multiplication of cancerous cells. This prevents the abnormal growth of cancer cells and thus reduces the further spread to other parts of the body.

Storage

• Store in a cool and dry place away from sunlight.• Keep Dacoplice 45mg Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Side effects of Dacoplice 45mg Tablet

Pain In The Arm, Leg, Hand, Or Foot

Pain In The Muscles , Bones , Or Joints

Include omega-3 rich foods like fatty fish, ground flax, flaxseed oil, and walnuts.
Consume calcium-rich dairy products for bone health.
Eat green and leafy vegetables for essential nutrients.
Include lean protein sources like eggs and whole grains.
Use herbs and spices for added flavor and nutrition.
Choose fortified foods for extra nutritional benefits.
Get plenty of sleep for overall health and well-being.

Increased Blood Sugar Levels

Exercise regularly to maintain a healthy weight.
Follow a proper diet; avoid sugary snacks and drinks.
Manage stress with yoga or meditation.
Limit alcohol consumption.

Weakness

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Less Hunger

Prefer liquid food like juices and soups when you are not likely to eat.
Avoid spicy, fatty and fried foods as they cause stomach upset.
Eat small and frequent meals, avoiding large meals at a time.
Add healthy foods in your diet like fruits and vegetables.
Take starchy food like cereals, bread and potatoes etc.

Dehydration

Dehydration would need immediate medical attention if its severe where medical help can save you from crisis.
In case the level of dehydration is from mild to moderate, drink plenty of water for an immediate relief.
Seek a place where the surrounding temperature is less and try to stay away from heat and humidity.
Lie down by keeping a cool and wet towel on your forehead to prevent high temperature in your body to avoid dehydration.
Talk to your medical practitioner and use oral rehydrating salts to replace the lost salts from your body.

Sleeplessness

Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:

Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
Try relaxing techniques like deep breathing, mindfulness meditation and any others.
Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.

What if I have taken an overdose of Dacoplice 45mg Tablet

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, they may cause serious side effects or poisoning. If you suspect that you may have overdosed of Dacoplice 45mg Tablet or observe any side effects, please go to the emergency department of the closest hospital or nursing home. No specific side effects have been reported under these circumstances.

Drug Warnings

To treat your condition effectually, continue taking Dacoplice 45mg Tablet for the period that your doctor has prescribed. Avoid taking Dacoplice 45mg Tablet if you are allergic to it or any other components present in it. Caution should be exercised if you have/had liver or kidney disease, eye problems, lung disease other than lung cancer, severe cough, and breathing difficulty. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment. Effective birth control pills should be used for at least 17 days after the last dose of the medicine. Dacoplice 45mg Tablet may cause severe diarrhea, severe skin conditions, and Interstitial lung disease in some patients. Hence, inform your doctor about your complete medication and medical history before taking Dacoplice 45mg Tablet . Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. Avoid driving and operating machines, as this medicine may cause visual disturbances. This medicine is not recommended for use in children as the safety and efficacy are not established.

Drug-Drug Interactions

DacomitinibPantoprazole

Severe

DacomitinibLansoprazole

Severe

Drug-Drug Interactions

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DacomitinibPantoprazole

Severe

How does the drug interact with Dacoplice 45mg Tablet:
Taking Pantoprazole can make Dacoplice 45mg Tablet less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Pantoprazole with Dacoplice 45mg Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.

DacomitinibLansoprazole

Severe

How does the drug interact with Dacoplice 45mg Tablet:
Co-administration of Lansoprazole can make Dacoplice 45mg Tablet less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Lansoprazole with Dacoplice 45mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting to a doctor.

DacomitinibAtomoxetine

Severe

How does the drug interact with Dacoplice 45mg Tablet:
Taking Atomoxetine and Dacoplice 45mg Tablet may significantly increase the blood levels of atomoxetine. This can increase side effects (dizziness, dry mouth, loss of appetite, sleep disturbances, and heart palpitations).

How to manage the interaction:
Although taking Atomoxetine and Dacoplice 45mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, dry mouth, loss of appetite, sleep disturbances, and rapid heartbeats, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

DacomitinibEsomeprazole

Severe

How does the drug interact with Dacoplice 45mg Tablet:
Esomeprazole can make Dacoplice 45mg Tablet less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Esomeprazole with Dacoplice 45mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

After your treatment begins, several dietary adjustments can help you control side effects.
Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
Eat a healthy diet and exercise regularly to maintain proper weight.
Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
Performing yoga may also help in improving both physical and mental health.
Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
Get optimal sleep; rest well.
Avoid smoking and alcohol consumption.
Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Alcohol

Consult your doctor

It is unknown whether alcohol may interact with Dacoplice 45mg Tablet . However, as a precautionary measure, it is advisable not to take or limit alcohol. Consult your doctor for more information.

Pregnancy

Unsafe

Dacoplice 45mg Tablet is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Dacoplice 45mg Tablet . You should not become pregnant while you are taking Dacoplice 45mg Tablet and for at least 17 days after your last dose.

Breast Feeding

Unsafe

It is not known whether Dacoplice 45mg Tablet is present in human milk. However, you should not breastfeed while taking this medicine and, for 17 days after your last dose.

Driving

Unsafe

Dacoplice 45mg Tablet may cause blurred vision as a side effect. Hence, try to avoid driving, operating machinery, or engaging in any activity that needs clear vision until you are able to see clearly while you are on treatment with Dacoplice 45mg Tablet .

Liver

Caution

If you have mild to moderate liver problems, inform your doctor before taking Dacoplice 45mg Tablet . The dose of this medicine has to be adjusted in case you have severe liver disease.

Kidney

Caution

Inform your doctor before receiving Dacoplice 45mg Tablet if you have a history of kidney diseases. No dose adjustments are required in mild to moderate renal impairment.

Children

Unsafe

Dacoplice 45mg Tablet is not recommended for children as the safety and effectiveness were not established.

Heart

Please consult your doctor before receiving Dacoplice 45mg Tablet if you have pre-existing heart problems. Your doctor will prescribe Dacoplice 45mg Tablet if the benefits outweigh the risks.

Geriatrics

Consult your doctor

Please consult a doctor before administering Dacoplice 45mg Tablet to geriatric patients. Your doctor will prescribe Dacoplice 45mg Tablet if the benefits outweigh the risks.

FAQs

What is the use of Dacoplice 45mg Tablet ?

Dacoplice 45mg Tablet is used to treat Non-small cell lung cancer (NSCLC).

How does Dacoplice 45mg Tablet work?

Dacoplice 45mg Tablet contains Dacominitib, which works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells.

What are the first sign of lung cancer?

The most common sign of lung cancer is a cough that lasts long and gets worse with time. Sometimes, a patient may notice blood in the cough. Chest pain is also a sign of lung cancer, followed by coughing.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18Th Floor , Plot No. C-70, Â€˜Gâ€™ Block , Bandra Kurla Complex, Bandra East , Mumbai Â€“ 400051

Other Info - DAC0065

Author Details

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 18, 2025 | 11:51 AM IST

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What are the first sign of lung cancer?

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