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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Danolin 500 Tablet ER is used alone or with other medicines to treat angina pectoris. It helps prevent any further attack of angina by making the heart work more efficiently, and it is used as an add-on to existing treatment in patients whose disease is not adequately controlled by other medicines for angina pectoris, such as beta-blockers or calcium antagonists, or in patients who cannot take these medicines. In some cases, it may cause side effects such as constipation, dizziness, headache, or feeling sick. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Composition :

RANOLAZINE-500MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Danolin 500 Tablet ER

Danolin 500 Tablet ER is used to treat angina pectoris. Angina pectoris is discomfort in the chest or chest pain, which generally occurs due to coronary artery disease (CAD) when the heart and its muscles are not receiving enough oxygen and blood.

Danolin 500 Tablet ER contains Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels, through which calcium ions normally enter the cells.

You may sometimes experience constipation, dizziness, headache, or feeling sick. Most of these side effects of Danolin 500 Tablet ER do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

You can take Danolin 500 Tablet ER with food or as advised by your doctor. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Depending on your medical conditions, your doctor will advise the dose and duration of Danolin 500 Tablet ER.

Do not take Danolin 500 Tablet ER if you are allergic to any component in this medicine. Danolin 500 Tablet ER should not be stopped even if you feel better for the best results, as it prevents any future harm. If you stop taking the Danolin 500 Tablet ER on your own, your chest pain can come back in more severe form. If you plan to get pregnant or are pregnant or breastfeeding, please consult your doctor to avoid any unwanted harm to the baby. 

Uses of Danolin 500 Tablet ER

Danolin 500 Tablet ER used in the treatment of Angina Pectoris. The detailed use of Danolin 500 Tablet ER is as follows:

Treatment of Angina Pectoris: Danolin 500 Tablet ER is used in the treatment of angina pectoris by improving oxygen supply to the heart muscle and enhancing cardiac efficiency, particularly in areas with fixed epicardial lesions, thereby decreasing chest pain episodes and improving patient quality of life.

Directions for Use

• Danolin 500 Tablet ER can be taken with or without food. Avoid consuming grapefruit or grapefruit juice while taking ths medication. • It is usually taken twice daily at the same time each day or as prescribed by your doctor. • Swallow Danolin 500 Tablet ER as a whole with a glass of water. • Do not chew, crush, or break it.

Medicinal Benefits

  • Danolin 500 Tablet ER is prescribed for treating angina. Danolin 500 Tablet ER is an anti-anginal medication used to treat angina pectoris.
  • It reduces sodium ions' flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called ‘sodium-dependent calcium channels’ through which calcium ions normally enter the cells.
  • This medicine reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract.
  • Danolin 500 Tablet ER helps improve blood flow to the heart muscle and relieve the symptoms of angina pectoris.

How Danolin 500 Tablet ER Works

The active substance in Danolin 500 Tablet ER is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels, through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Danolin 500 Tablet ER is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Danolin 500 Tablet ER

Do not take more than the prescribed dose of Danolin 500 Tablet ER as it may cause overdose. The symptoms of overdose include nausea, vomiting, confusion, dizziness, double vision, fainting, difficulty speaking, uncontrollable shaking of a part of the body, hallucinations and burning, pain, numbness, or tingling in any part of the body. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Danolin 500 Tablet ER if you are allergic to any component in this medicine.
  • Danolin 500 Tablet ER should not be stopped even if you feel better for the best results, as it prevents any future harm. If you stop taking the Danolin 500 Tablet ER on your own, your chest pain can come back in a more severe form.
  • Danolin 500 Tablet ER should be taken with caution in liver disease, kidney disease, or heart problems.
  • Inform your doctor if you are pregnant, planning for pregnancy, or breastfeeding before taking Danolin 500 Tablet ER.
  • Also, grapefruit juice should be avoided while taking Danolin 500 Tablet ER.
  • As a precautionary measure, avoid junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery.
  • Do regular exercise to avoid abdominal heaviness.

Diet & Lifestyle Advise

  • Maintain a healthy lifestyle by exercising regularly, maintaining weight, and eating a healthy diet.
  • If you suffer from kidney or liver disease, please inform your doctor before taking the Danolin 500 Tablet ER.
  • Alcohol consumption along with Danolin 500 Tablet ER should be avoided as it may cause excessive drowsiness and increase muscle pain.

Habit Forming

No

Therapeutic Class

ANTIANGINALS
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Alcohol

Safe if prescribed

Danolin 500 Tablet ER does not have any reported interaction; hence, if you experience any difficulty, discuss with your doctor.

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Pregnancy

Unsafe

Danolin 500 Tablet ER should not be used when pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Danolin 500 Tablet ER.

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Breast Feeding

Consult your doctor

Danolin 500 Tablet ER should not be used in nursing mothers. Please consult the doctor if you have any concerns regarding this.

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Driving

Safe if prescribed

Danolin 500 Tablet ER does not have any reported interaction; hence, in case you experience any difficulty, discuss with your doctor.

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Liver

Caution

Danolin 500 Tablet ER to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Danolin 500 Tablet ER to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Danolin 500 Tablet ER is not recommended for children below the age of 18. The safety and effectiveness of Danolin 500 Tablet ER have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

Have a query?

FAQs

Danolin 500 Tablet ER is used alone or with other medicines to treat angina pectoris.

The active substance in Danolin 500 Tablet ER is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called sodium-dependent calcium channels through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Danolin 500 Tablet ER is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

No, Danolin 500 Tablet ER does not stop acute attacks (sudden attacks) of angina, but Danolin 500 Tablet ER helps prevent a new attack.

No, alcohol should not be taken with Danolin 500 Tablet ER as it may lead to unwanted side effects and increase angina attacks.

Yes, smoking (tobacco) decreases the efficacy of Danolin 500 Tablet ER, especially when taken for angina (chest pain), so it should be avoided while taking Danolin 500 Tablet ER.

Yes, Danolin 500 Tablet ER can cause an upset stomach when taken empty stomach. So, to avoid it, Danolin 500 Tablet ER should be taken with a meal for best results.

Yes, Danolin 500 Tablet ER can cause drowsiness. If you feel excessively sleepy, please consult your doctor for better advice.

Some major side effects include a rapid, pounding, or irregular heartbeat, difficulty breathing, and fainting. If you encounter any of these symptoms, contact your doctor immediately.

Do not take more than the prescribed dose of Danolin 500 Tablet ER as it may cause overdose. The symptoms of overdose include nausea, vomiting, confusion, dizziness, double vision, fainting, difficulty speaking, uncontrollable shaking of a part of the body, hallucinations and burning, pain, numbness, or tingling in any part of the body. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Danolin 500 Tablet ER may increase the blood levels and effects of metoprolol. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects.

Danolin 500 Tablet ER might raise metformin levels, increasing the risk of lactic acidosis. If you are prescribed ranolazine while taking metformin, discuss it with a healthcare physician. They may offer a lesser dose of metformin as a safer alternative.

You can take it if prescribed by the doctor. However, limit simvastatin to 20 mg once daily in individuals taking any dose of Danolin 500 Tablet ER.

Country of origin

India
Other Info - DA26039

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