Dapamac-Trio 1000 mg Tablet 10's
MRP ₹183.5
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About Dapamac-Trio 1000 mg Tablet
Dapamac-Trio 1000 mg Tablet is an antidiabetic medicine used to treat Type II Diabetes. In type 2 diabetes, the pancreas does not produce enough insulin, or the body is unable to use insulin effectively. As a result, blood sugar levels become elevated.
Dapamac-Trio 1000 mg Tablet contains Dapagliflozin, Sitagliptin, and Metformin. It works by removing excess sugar from the body through urine, increasing the levels of certain natural substances that lower blood sugar when it is high, reducing sugar production by cells in the liver, and delaying sugar absorption from the intestines.
Take Dapamac-Trio 1000 mg Tablet as advised by your doctor. Dapamac-Trio 1000 mg Tablet may cause certain side effects such as vomiting, nausea, abdominal pain, headache and stomach upset. Most of these side effects do not need medical attention and resolve over time. If these side effects persist or worsen, please consult your doctor.
Do not take Dapamac-Trio 1000 mg Tablet if you are allergic to any of its components. Inform your doctor about your medical history and the medicines you are taking, including herbs and supplements, before starting the treatment with Dapamac-Trio 1000 mg Tablet . Let your doctor know if you are pregnant or breastfeeding before taking Dapamac-Trio 1000 mg Tablet . It is not recommended for use in children below 18 years of age.
Uses of Dapamac-Trio 1000 mg Tablet
Dapamac-Trio 1000 mg Tablet is used in the treatment of Type II Diabetes Mellitus. The detailed uses of Dapamac-Trio 1000 mg Tablet are as follows:
- Type 2 Diabetes Management: Dapamac-Trio 1000 mg Tablet is used to improve blood sugar control in adults with type 2 diabetes. It combines three agents that work together to reduce glucose production, enhance insulin response, and promote glucose excretion through urine.
- Cardiovascular and Kidney Protection: Dapamac-Trio 1000 mg Tablet helps lower the risk of heart failure and diabetic kidney disease by improving vascular function, reducing albuminuria, and supporting healthy blood pressure levels.
- Weight and Metabolic Control: Dapamac-Trio 1000 mg Tablet supports weight loss and improves metabolic health by reducing excess glucose and enhancing insulin sensitivity, making it beneficial for overweight or obese diabetic patients.
- HbA1c Reduction and Glycemic Stability: Dapamac-Trio 1000 mg Tablet effectively lowers HbA1c levels and helps maintain steady blood sugar throughout the day, reducing the risk of hypoglycemia and long-term complications.
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Directions for Use
- Take Dapamac-Trio 1000 mg Tablet with food to reduce stomach upset or gastrointestinal side effects.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Swallow the medicine as a whole with a glass of water.
- Do not crush, break, or chew it.
Key Benefits
- Dapamac-Trio 1000 mg Tablet is a combination of three antidiabetic medicines: Sitagliptin, Dapagliflozin, and Metformin, used in the management of Type 2 Diabetes Mellitus, along with proper diet and exercise.
- Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that helps increase insulin release and decrease glucagon levels in the body, lowering blood sugar levels when they are high.
- Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, works by removing excess glucose through the urine, thereby lowering blood sugar levels.
- Metformin is a biguanide which reduces the amount of sugar produced by the liver and delays glucose absorption from the intestine.
- It improves the body’s sensitivity to insulin, promoting better glucose uptake by muscles and tissues.
- The combined effect of these three drugs offers multi-targeted control of blood sugar levels, especially in patients not controlled by single or dual therapy.
- Dapamac-Trio 1000 mg Tablet helps manage blood glucose levels and prevents diabetes-related complications, such as eye problems, nerve problems, and kidney impairment.
How Dapamac-Trio 1000 mg Tablet Works
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- Preventing Vomiting (Before it Happens)
- Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
- Having a small meal before taking your medication can help reduce nausea and vomiting.
- Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
- Managing Vomiting (If it Happens)
- Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
- What to Do if Vomiting Persists
- Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
- Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
- To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
- Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
- Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
- Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
- Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
- If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
- Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
- Wear masks, gloves and other protective clothing.
- Cover sneezes and coughs with a medical mask or tissue or your elbow.
- Take vaccinations to enhance your immunity to specific diseases.
- Clean your utensils, linen and surfaces regularly.
- Inform your doctor about the symptoms you're experiencing due to medication.
- Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
- Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
- Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
- Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
- If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
- Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
- Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
- Make medication adjustments as recommended by your doctor to prevent future episodes.
- Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
- Monitor your blood sugar levels closely for patterns and changes.
- Track your progress by recording your blood sugar levels, food intake, and physical activity.
- Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
- Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
- Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
- Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
- Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
- Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
- Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
- Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
What if I have taken an overdose of Dapamac-Trio 1000 mg Tablet
Drug Warnings
- Dapamac-Trio 1000 mg Tablet should be avoided if you are allergic to any of the components in it.
- Before starting treatment, inform your doctor about your medical history and the medications you are taking, including any herbs and supplements. This can help prevent unwanted effects.
- Dapamac-Trio 1000 mg Tablet is not recommended for use in patients with severe liver or kidney disease.
- Consult your doctor if you are pregnant or breastfeeding.
- It is not recommended for use in children below 18 years of age.
- Avoid drinking alcohol while on Dapamac-Trio 1000 mg Tablet as it increases the risk of hypoglycemia and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body).
Drug-Drug Interactions
Drug-Drug Interactions
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Co-administration of Iopanoic acid with Dapamac-Trio 1000 mg Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Dapamac-Trio 1000 mg Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
Co-administration of Iohexol with Dapamac-Trio 1000 mg Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Dapamac-Trio 1000 mg Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Co-administration of Iopromide with Dapamac-Trio 1000 mg Tablet can increase the risk of lactic acidosis.
How to manage the interaction:
Taking Iopromide with Dapamac-Trio 1000 mg Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
Co-administration of Iodixanol with Dapamac-Trio 1000 mg Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Dapamac-Trio 1000 mg Tablet with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
Co-administration of Iopamidol with Dapamac-Trio 1000 mg Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Dapamac-Trio 1000 mg Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
Co-administration of Ioglycamic acid with Dapamac-Trio 1000 mg Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Dapamac-Trio 1000 mg Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Co-administration of Dapamac-Trio 1000 mg Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).
How to manage the interaction:
Taking Dapamac-Trio 1000 mg Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.
Co-administration of Iomeprol with Dapamac-Trio 1000 mg Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Dapamac-Trio 1000 mg Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
Co-administration of Iotroxic acid with Dapamac-Trio 1000 mg Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Dapamac-Trio 1000 mg Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
Co-administration of Ioglicic acid with Dapamac-Trio 1000 mg Tablet can increase the risk of side effects.
How to manage the interaction:
Taking Dapamac-Trio 1000 mg Tablet with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Try doing 30 minutes of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise weekly.
- Include whole-grain foods, fruits and veggies, and other fibre-enriched foods.
- Add omega-3 fatty acid-containing oils for daily cooking.
- Avoid too much stress, as it may elevate your blood sugar level. To control stress-related blood sugar changes, you can adopt stress management techniques like mindfulness, meditation, or yoga.
- Weight loss gradually to achieve a healthy body mass index (18.5 to 24.9).
- Keep your blood pressure as normal (140/90) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
- Avoid smoking and alcohol consumption while on treatment with Dapamac-Trio 1000 mg Tablet .
- Take short, frequent meals, and avoid prolonged fasting when taking Dapamac-Trio 1000 mg Tablet .
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Alcohol
Safe if prescribed
Alcohol increases the impact of metformin on lactate metabolism. Hence, you should not consume excessive amounts of alcohol, either temporarily or permanently, while taking Dapamac-Trio 1000 mg Tablet .
Pregnancy
Consult your doctor
There are no adequate studies on the effect of Dapamac-Trio 1000 mg Tablet in pregnancy. If you are pregnant or planning pregnancy, inform your doctor before taking Dapamac-Trio 1000 mg Tablet .
Breast Feeding
Consult your doctor
Dapamac-Trio 1000 mg Tablet is generally not recommended in breastfeeding. Hence, if you are breastfeeding, inform your doctor before using Dapamac-Trio 1000 mg Tablet .
Driving
Safe if prescribed
Dapamac-Trio 1000 mg Tablet usually does not affect your ability to drive or operate machinery.
Liver
Consult your doctor
Use Dapamac-Trio 1000 mg Tablet with caution, as lactic acidosis can occur due to metformin accumulation. The risk increases with hepatic insufficiency. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Kidney
Consult your doctor
Renal impairment also increases the risk of lactic acidosis. Hence, Dapamac-Trio 1000 mg Tablet should be used with caution if you have kidney problems. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
Safe if prescribed
Dapamac-Trio 1000 mg Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.
Heart
Please consult your doctor before receiving Dapamac-Trio 1000 mg Tablet if you have pre-existing heart problems. Your doctor will prescribe Dapamac-Trio 1000 mg Tablet if the benefits outweigh the risks.
Geriatrics
Consult your doctor
Please consult a doctor before administering Dapamac-Trio 1000 mg Tablet to geriatric patients. Your doctor will prescribe Dapamac-Trio 1000 mg Tablet if the benefits outweigh the risks.
FAQs
Dapamac-Trio 1000 mg Tablet is used to treat type II diabetes mellitus, a condition wherein the body doesn't use insulin effectively, which causes unusual blood glucose levels.
Dapamac-Trio 1000 mg Tablet is a combination medicine containing Sitagliptin that enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations. Dapagliflozin helps remove excess sugar from the body via urine. Metformin helps reduce the sugar production by cells in the liver and delays sugar absorption from the intestines.
If you forget to take Dapamac-Trio 1000 mg Tablet , take it as soon as you remember. However, if it's time for the next dose, avoid taking it and do not double-dose to make up the missed dose. Taking an overdose might cause your sugar level to fall rapidly.
Dapamac-Trio 1000 mg Tablet may cause certain side effects such as vomiting, nausea, abdominal pain, headache and allergic reactions. If these side effects persist or worsen, please consult your doctor.
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Reference
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022044s022lbl.pdf
- https://medlineplus.gov/druginfo/meds/a606023.html
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s020lbl.pdf
- https://www.drugs.com/metformin.html
- https://www.nhs.uk/medicines/sitagliptin/about-sitagliptin/#:~:text=Sitagliptin%20is%20prescribed%20for%20people,is%20only%20available%20on%20prescription.
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