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  1. Home
  2. Medicine

  3. Dapodafil Tablet

Prescription drug
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Dapodafil Tablet, Pack of 1
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Composition :

DAPOXETINE-30MG + TADALAFIL-10MG

Manufacturer/Marketer :

Bioceutics Inc

Consume Type :

ORAL

Return Policy :

Not Returnable

About Dapodafil Tablet

Dapodafil Tablet is used to treat erectile dysfunction and premature ejaculation in men. Erectile dysfunction is the inability to keep a hard and erect penis suitable for sexual activity. Premature ejaculation is a problem in which a man ejaculates sooner than his partner during sexual intercourse.

Dapodafil Tablet contains Tadalafil and Dapoxetine. Tadalafil works by inhibiting the phosphodiesterase enzyme, which breaks down cGMP and causes smooth muscle relaxation and vasodilation (widening) of blood vessels in the penis. Dapoxetine works by increasing the serotonin level in nerves, which improves control over ejaculation and hence increases the time taken to ejaculate.

In some cases, you may experience nausea, dizziness, vomiting, dryness in the mouth, indigestion, nosebleeds, headache, and flushing. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Do not take Dapodafil Tablet if you take nitrates (used to treat angina), riociguat (used to treat pulmonary hypertension), or alpha-blockers if you have heart problems or stroke, low or uncontrolled high blood pressure. Dapodafil Tablet is not intended for use in women. Dapodafil Tablet may cause dizziness, so drive with caution.

Uses of Dapodafil Tablet

Dapodafil Tablet is used in the treatment of erectile dysfunction and premature ejaculation. The detailed uses of Dapodafil Tablet are as follows:

  • Management of Erectile Dysfunction: Dapodafil Tablet is commonly prescribed to help men with erectile dysfunction achieve and maintain an erection during sexual activity.
  • Improvement of Sexual Performance: Dapodafil Tablet can increase blood flow to the penis, allowing for improved sexual response.
  • Support for Psychological Factors: Dapodafil Tablet can help address psychological causes of erectile dysfunction, such as anxiety or stress, by enabling better physical responses.
  • Treatment of Premature Ejaculation: Dapodafil Tablet may be used to help manage issues related to premature ejaculation, contributing to a more satisfying sexual experience.
  • Facilitation of Reproductive Health: By addressing erectile dysfunction, Dapodafil Tablet can play a role in supporting overall reproductive health in men, potentially improving fertility outcomes.

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Directions for Use

  • Take Dapodafil Tablet with or without food, or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Dapodafil Tablet is a combination drug containing 'impotent agents', primarily used to treat erectile dysfunction (impotence) and premature ejaculation in men.
  • Dapodafil Tablet contains Tadalafil and  Dapoxetine.
  • Tadalafil works by inhibiting the phosphodiesterase enzyme, which leads to the breakdown of cGMP and causes relaxation of smooth muscles and vasodilation (widening) of blood vessels in the penis.
  • Dapodafil Tablet helps to treat erectile dysfunction and symptoms of an enlarged prostate.
  • Dapoxetine works by increasing the serotonin level in nerves, which improves control over ejaculation and increases the time taken to ejaculate.

How Dapodafil Tablet Works

Dapodafil Tablet contains Tadalafil and Dapoxetine. Tadalafil works by inhibiting the phosphodiesterase enzyme, which leads to the breakdown of cGMP and causes relaxation of smooth muscles and vasodilation (widening) of blood vessels in the penis. Thereby, it helps to treat erectile dysfunction and symptoms of an enlarged prostate. Dapoxetine works by increasing the serotonin level in nerves, which improves control over ejaculation and hence increases the time taken to ejaculate.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Dapodafil Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Do not stand up suddenly. Lie down and get up slowly only when you feel better.
  • Avoid alcohol and large meals.
  • Drink enough water before standing for long periods.
  • Exercise regularly; however, avoid exercising in extreme heat.
  • Eat small, low-carb meals.
  • Wear compression stockings.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

What if I have taken an overdose of Dapodafil Tablet

Do not take more than the prescribed dose of Dapodafil Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Dapodafil Tablet if you are allergic to any of its contents.
  • Also, avoid taking Dapodafil Tablet if you are taking nitrates (used to treat angina), riociguat (used to treat pulmonary hypertension), or alpha-blockers; if you have heart problems or stroke, low blood pressure, or uncontrolled high blood pressure, or if you have ever had a loss of vision.
  • Inform your doctor before taking Dapodafil Tablet if you have sickle cell anemia (abnormal red blood cells), multiple myeloma (cancer of bone marrow), leukemia (blood cell cancer), deformation in the penis, or severe kidney or liver problems.
  • Consult your doctor immediately if you experience loss of vision or hearing while taking Dapodafil Tablet.
  • Dapodafil Tablet is not intended for use in women.
  • Dapodafil Tablet may cause dizziness, so drive with caution.
  • Avoid consuming alcohol as it might cause increased dizziness.
  • Dapodafil Tablet should not be given to children as safety and effectiveness have not been established.  
  • Do not take Dapodafil Tablet if you have taken an MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days.

Drug-Drug Interactions

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TadalafilRiociguat
Critical
TadalafilNitroprusside
Critical

Drug-Drug Interactions

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TadalafilRiociguat
Critical
How does the drug interact with Dapodafil Tablet:
Taking Dapodafil Tablet with Riociguat may increase the risk or severity of lower the blood pressure.

How to manage the interaction:
Taking Riociguat with Dapodafil Tablet is generally not recommended as it can lead to an interaction, but it can be taken together if prescribed by a doctor. However, if you experience dizziness, headache, and nasal congestion consult a doctor. Do not discontinue any medications without consulting a doctor.
TadalafilNitroprusside
Critical
How does the drug interact with Dapodafil Tablet:
Taking Dapodafil Tablet with Nitroprusside can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Dapodafil Tablet with Nitroprusside is generally avoided as it can lead to an interaction, but it can be taken if prescribed by a doctor. If you experience dizziness, or heart palpitations, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
TadalafilIsosorbide dinitrate
Critical
How does the drug interact with Dapodafil Tablet:
Taking Dapodafil Tablet with Isosorbide dinitrate can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Isosorbide dinitrate with Dapodafil Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TadalafilAmyl nitrite
Critical
How does the drug interact with Dapodafil Tablet:
Taking Dapodafil Tablet with Amyl Nitrite can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Dapodafil Tablet with Amyl nitrite is generally avoided as it can lead to interaction. They can be taken only when advised by a doctor. Seek immediate medical attention if you experience symptoms like dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TadalafilIsosorbide mononitrate
Critical
How does the drug interact with Dapodafil Tablet:
Coadministration of Dapodafil Tablet with Isosorbide mononitrate can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Isosorbide mononitrate with Dapodafil Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TadalafilSildenafil
Severe
How does the drug interact with Dapodafil Tablet:
Coadministration of Dapodafil Tablet and Sildenafil may increase the risk of developing low blood pressure.

How to manage the interaction:
Coadministration of Dapodafil Tablet and Sildenafil can lead to an interaction, but it can be taken if a doctor advises. However, if you experience dizziness, headache, heart palpitations consult a doctor immediately. Do not stop using any medications without a doctor's advice.
TadalafilTelithromycin
Severe
How does the drug interact with Dapodafil Tablet:
Using Dapodafil Tablet with Telithromycin may significantly increase the blood levels and effects of Dapodafil Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Co-administration of Dapodafil Tablet with Telithromycin can result in an interaction, but it can be taken if a doctor has advised it. Contact a doctor if you experience shortness of breath, visual disturbances, hearing loss, or irregular heartbeat consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
TadalafilVoriconazole
Severe
How does the drug interact with Dapodafil Tablet:
Using Dapodafil Tablet together with voriconazole may significantly increase the blood levels and effects of Dapodafil Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Voriconazole and Dapodafil Tablet together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact a doctor right away. Do not discontinue any medications without consulting a doctor.
TadalafilMiconazole
Severe
How does the drug interact with Dapodafil Tablet:
Coadministration of Miconazole with Dapodafil Tablet may increase blood levels and effects of Dapodafil Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between miconazole and Dapodafil Tablet, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience shortness of breath, dizziness, visual disturbances, or irregular heartbeat. Do not stop using medications without a doctor's advice.
TadalafilKetoconazole
Severe
How does the drug interact with Dapodafil Tablet:
Coadministration of Ketoconazole with Dapodafil Tablet may increase the blood levels and effects of Dapodafil Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Ketoconazole and Dapodafil Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if your condition worsens or you experience any symptoms like chest pain or tightness, irregular heartbeat, shortness of breath, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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DAPOXETINE-30MG+TADALAFIL-10MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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DAPOXETINE-30MG+TADALAFIL-10MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Consuming grapefruit juice with dapoxetine and tadalafil can increase their blood levels and effects. Limit or avoid consuming grapefruit juice while taking dapoxetine and tadalafil.

Diet & Lifestyle Advise

  • Maintaining a healthy weight, eating a balanced diet, and regularly exercising may help you manage erectile dysfunction.
  • Avoid alcohol consumption to treat your condition effectively, as consuming an excessive amount of alcohol may temporarily impair your ability to get an erection.
  • Avoid the use of tobacco.
  • Share intimate time with your partner.
  • Stay sexually active to prevent further problems with erectile dysfunction.

Habit Forming

No

Therapeutic Class

IMPOTENT AGENTS

Dapodafil Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

You are advised not to consume alcohol while taking Dapodafil Tablet as it may cause increases dizziness.

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Pregnancy

Unsafe

Dapodafil Tablet contains Tadalafil, which belongs to pregnancy category B. Dapodafil Tablet is not intended for use in women.

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Breast Feeding

Unsafe

Dapodafil Tablet is not intended for use in women.

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Driving

Caution

Dapodafil Tablet may cause dizziness. Therefore, you are advised to drive and operate machinery only if you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed. Please consult your doctor before taking Dapodafil Tablet if you have liver impairment/liver disease or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed. Please consult your doctor before taking Dapodafil Tablet if you have kidney impairment/kidney disease or any concerns regarding this.

bannner image

Children

Unsafe

Dapodafil Tablet should not be given to children as safety and effectiveness have not been established.

FAQs

Dapodafil Tablet is used to treat erectile dysfunction (impotence) and premature ejaculation in men.

Dapodafil Tablet works by relaxing the blood vessels in the penis, thereby allowing the blood flow into the penis when the person is sexually excited.

Yes, using Dapodafil Tablet can cause dry mouth. If you experience dry mouth or feel excessively thirsty, drink plenty of water and increase fluid intake. You may also keep a lip balm with you if your lips are also dry.

No, do not take Dapodafil Tablet with nitrates. Taking Dapodafil Tablet with medicines used to treat angina/chest pain, such as nitrates/nitroglycerin, may cause severe lowering of blood pressure. You are advised not to take Dapodafil Tablet if you are taking nitrates or have a history of heart attack/stroke.

No, Dapodafil Tablet should not be taken along with blood-pressure-lowering medicines. Dapodafil Tablet relaxes and widens blood vessels, lowering blood pressure. Therefore, if Dapodafil Tablet is taken with blood pressure-lowering medicines, it could lead to a severe blood pressure decrease.

It usually takes 30-60 minutes for Dapodafil Tablet to show its effect. You should be able to get an erection at any time between 30 minutes to 36 hours after taking Dapodafil Tablet. However, you need to be sexually excited for Dapodafil Tablet to work.

No, it is recommended not to take Dapodafil Tablet along with MAO inhibitor (a medicine for depression) as Dapodafil Tablet contains Dapoxetine, which is known to contraindicate if taken along with MAO inhibitor. So, concurrent use of Dapodafil Tablet and MAO inhibitor should be avoided, and a gap of 14 days should be maintained between the last dose of MAO inhibitor and the first dose Dapodafil Tablet.

Dapodafil Tablet may cause side effects such as nausea, dizziness, vomiting, dry mouth, indigestion, nosebleeds, headache, and flushing. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Dapodafil Tablet may cause dizziness. Therefore you are advised to drive and operate machinery only if you are alert.

Store Dapodafil Tablet at room temperature, in a dry place. Keep out of sight and reach of children.

Inform your doctor before taking Dapodafil Tablet if you have sickle cell anemia (abnormal red blood cells), multiple myeloma (cancer of bone marrow), leukemia (blood cell cancer), deformation in penis, severe kidney or liver problems.

Country of origin

India
Other Info - DA45678

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Nov 5, 2025 | 7:46 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021368s20s21lbl.pdf
  2. https://www.nhs.uk/medicines/tadalafil/
  3. https://www.drugs.com/tadalafil.html
  4. https://www.medicines.org.uk/emc/files/pil.1269.pdf
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