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Darif Tablet 10's, Pack of 10 TABLETS
Darif Tablet 10's, Pack of 10 TABLETS
Darif Tablet 10's, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Darif Tablet is used in the treatment of overactive bladder (OAB) symptoms. It contains Darifenacin, which relaxes the urinary bladder muscles which in turn decreases the activity of the overactive bladder. It stops these sudden contractions of urinary bladder muscles thereby enabling control over urination. Thus, it increases the amount and volume of urination that can be held by your bladder. It may cause side effects such as dryness in the mouth, constipation, nausea, blurred vision, indigestion, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

DARIFENACIN-7.5MG

Manufacturer/Marketer :

Alembic Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Darif Tablet

Darif Tablet belongs to the group of medications called ‘antimuscarinic' or 'antispasmodics' primarily used in the treatment of overactive bladder (OAB) symptoms. Overactive bladder is a condition in which the urinary bladder muscles constrict uncontrollably thereby causing an urgent need to urinate, frequent urination, and inability to control urination.

Darif Tablet contains ‘Darifenacin’ that relaxes the urinary bladder muscles which in turn decreases the activity of the overactive bladder. In an overactive bladder, muscle contractions occur before the full expansion of the bladder causing the patient to have frequent urges to urinate. Darif Tablet stops these sudden contractions of urinary bladder muscles thereby enabling control over urination. Thus, it increases the amount and volume of urination that can be held by your bladder.

Take Darif Tablet as prescribed by your doctor. You are advised to take Darif Tablet for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience dryness in the mouth, constipation, nausea, blurred vision, indigestion, and headache. Most of these side effects of Darif Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before starting Darif Tablet , please inform your doctor if you have any allergy with this Darif Tablet or any other medicine or any type of foods. Talk to your doctor if you have glaucoma, liver disease. If you have trouble passing urine or slow clearing your stomach, then inform your doctor. Do not start, stop, or change the dose of Darif Tablet without checking with your doctor. Inform your doctor if you are pregnant or plan on becoming pregnant. Inform your doctor if you are breast-feeding. You will need to discuss any risks to your baby.

Uses of Darif Tablet

Treatment of Overactive bladder (urinary incontinency).

Directions for Use

Swallow Darif Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Darif Tablet contains ‘Darifenacin’ that belongs to the class of medications called 'anticholinergics' or ‘antimuscarinic’. It can decrease the activity of the overactive bladder. In an overactive bladder, muscle contractions occur before the full expansion of the bladder causing the patient to have frequent urges to urinate. Darif Tablet can stop these sudden contractions of bladder muscles. It enables control over urination and increases the amount of urine that can be held by your bladder.

How Darif Tablet Works

Darif Tablet contains ‘Darifenacin’ that relaxes the urinary bladder muscles which in turn decreases the activity of the overactive bladder. In an overactive bladder, muscle contractions occur before the full expansion of the bladder causing the patient to have frequent urges to urinate. Darif Tablet stops these sudden contractions of urinary bladder muscles thereby enabling control over urination. Thus, it increases the amount and volume of urination that can be held by your bladder.

Storage

Store in a cool and dry place away from sunlight
Side effects of Darif Tablet
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Eat vitamin A-rich foods like fish liver, chicken, eggs, carrots, lemons, and mangoes in your diet.
  • Eat green leafy vegetables, meat, and dairy products, and increase the consumption of omega-3 fatty acids found in salmon and walnuts.
  • Examine your eyes regularly to detect any underlying issues.
  • Stay hydrated by drinking plenty of water.
  • Eat a well-balanced diet that includes more vegetables, fruits, fish, whole grains, nuts, legumes, and olive oil, and less dairy, meat, and saturated fats.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of Darif Tablet

Do not take more than the prescribed dose of Darif Tablet as it may cause overdose resulting in vision problems. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Before starting Darif Tablet , please inform your doctor if you have any allergy with this Darif Tablet or any other medicine or any type of foods. Talk to your doctor if you have glaucoma, liver disease. If you have trouble passing urine or slow clearing your stomach, then inform your doctor. Do not start, stop, or change the dose of Darif Tablet without checking with your doctor. A very bad reaction called angioedema (swelling of the face, hands, eyes, lips, throat, tongue, or difficulty in breathing and swallowing) has happened with Darif Tablet .  Get medical help immediately if you have any of these symptoms. Sometimes, this may be life-threatening. Avoid driving and doing other activities that require concentration until you see how Darif Tablet affects you. Inform your doctor if you are pregnant or plan on becoming pregnant. Inform your doctor if you are breast-feeding. You will need to discuss any risks to your baby.

Drug-Drug Interactions

verifiedApollotooltip
DarifenacinPotassium citrate
Critical
DarifenacinPotassium chloride
Critical

Drug-Drug Interactions

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DarifenacinPotassium citrate
Critical
How does the drug interact with Darif Tablet:
Taking Darif Tablet and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Darif Tablet with Potassium citrate is not recommended, as it may lead to an interaction but can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
DarifenacinPotassium chloride
Critical
How does the drug interact with Darif Tablet:
Taking Darif Tablet with Potassium chloride(oral capsule or tablet) can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Darif Tablet with Potassium chloride(oral capsule or tablet) is not recommended, as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not stop taking any medications without doctor's advise.
DarifenacinEliglustat
Critical
How does the drug interact with Darif Tablet:
Darif Tablet can significantly increase the blood levels of eliglustat. This may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Darif Tablet with Eliglustat is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not stop any medications without doctor's advise.
DarifenacinThioridazine
Critical
How does the drug interact with Darif Tablet:
Using thioridazine together with Darif Tablet may increase the blood levels of thioridazine and cause an irregular heart rhythm.

How to manage the interaction:
Taking Darif Tablet with Thioridazine is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop any medications without doctor's advise.
DarifenacinMifepristone
Severe
How does the drug interact with Darif Tablet:
Co-administration of Darif Tablet with mifepristone may significantly increase the levels of Darif Tablet, which may increase the risk of side effects.

How to manage the interaction:
Taking Darif Tablet with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience symptoms such as nausea, vomiting, constipation, abdominal cramping, or dry mouth. Do not discontinue any medications without consulting a doctor.
DarifenacinAtazanavir
Severe
How does the drug interact with Darif Tablet:
Combining Darif Tablet with Atazanavir may significantly increase the blood levels of Darif Tablet.

How to manage the interaction:
Although taking Darif Tablet and Atazanavir together can cause an interaction, it can be taken if your doctor has suggested it. If you're having symptoms like nausea, dry mouth, abdominal pain, constipation, and heartburn, contact a doctor. Do not stop using any medications without a doctor's advice.
DarifenacinItraconazole
Severe
How does the drug interact with Darif Tablet:
Darif Tablet blood levels may be significantly raised when itraconazole and Darif Tablet are combined.

How to manage the interaction:
Darif Tablet and Itraconazole may interact, however they are still usable in the event that a doctor recommends them. Consult a physician if you have heartburn, dry mouth, digestive discomfort, constipation, or nausea. Never stop taking any medications without talking to a doctor.
DarifenacinNefazodone
Severe
How does the drug interact with Darif Tablet:
Combining Darif Tablet with Nefazodone may significantly increase the blood levels of Darif Tablet.

How to manage the interaction:
Although taking Darif Tablet and Nefazodone together can cause an interaction, it can be taken if your doctor has suggested it. If you're having symptoms like nausea, dry mouth, abdominal pain, constipation, and heartburn, contact a doctor. Do not stop using any medications without a doctor's advice.
DarifenacinIndinavir
Severe
How does the drug interact with Darif Tablet:
Combining Darif Tablet with Indinavir may significantly increase the blood levels of Darif Tablet.

How to manage the interaction:
Although taking Darif Tablet and Indinavir together can cause an interaction, it can be taken if your doctor has suggested it. If you're having symptoms like nausea, dry mouth, abdominal pain, constipation, and heartburn, contact a doctor. Do not stop using any medications without a doctor's advice.
DarifenacinErgotamine
Severe
How does the drug interact with Darif Tablet:
Co-administration of Darif Tablet and Ergotamine can increase the levels of Ergotamine.

How to manage the interaction:
Although there is a possible interaction between Darif Tablet and Ergotamine, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual side effects, contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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DARIFENACIN-7.5MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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DARIFENACIN-7.5MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
The consumption of grapefruit juice with Darif Tablet may increase blood levels of Darif Tablet. Avoid consumption of Darif Tablet with grapefruit juice.

Diet & Lifestyle Advise

  • Eat fresh fruits like pears, banana, citrus fruits, and green vegetables like beans and potatoes.
  • Try to take cranberry juice as it helps in minimizing urinary infections.
  • Avoid coffee, tea, and carbonated drinks that contain caffeine.
  • Do not consume processed, fried, or spicy foods, as these foods can irritate your bladder. Limit alcohol intake as it can increase the risk of side-effects.
  • Quit smoking and exercise regularly.

Habit Forming

No

Therapeutic Class

ANTICHOLINERGICS

Darif Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid taking alcohol as it may increase the risk of dizziness.

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Pregnancy

Unsafe

Darif Tablet is a category C medicine. It should be used in pregnant women if the benefits outweigh the risks.

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Breast Feeding

Caution

Darif Tablet should be used in breastfeeding mothers only if clinically needed.

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Driving

Caution

Darif Tablet may cause dizziness and blurred vision and sleepiness. So, avoid driving or operating heavy machinery after using Darif Tablet .

bannner image

Liver

Caution

Darif Tablet should be used with caution in patients with liver diseases

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Kidney

Caution

Darif Tablet should be used with caution in patients with kidney diseases.

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Children

Unsafe

Not recommended for use in children below 18 years of age due to a lack of data on safety and efficacy.

Have a query?

FAQs

Darif Tablet is used in the treatment of overactive bladder (OAB) symptoms such as strong urge to urinate, frequent urination, and reduced urine flow.

Darif Tablet contains Darifenacin, which prevents the sudden bladder muscle contractions and increases the volume and amount of urine that the bladder can hold. Thus, Darif Tablet helps to control the release of urine and helps reduce symptoms of OAB like a strong need to urinate, frequent urination, and reduced urine flow.

Darif Tablet may cause blurred vision in some cases and may harm your thinking or reactions. Consult your doctor immediately if this condition persists or worsens while using this Darif Tablet .

Darif Tablet is used to treat symptoms of overactive bladder like sudden or frequent rush to the toilet or outflow of urine.

Antifungal medicine may interact with Darif Tablet . So, inform your doctor about all the prescription and non-prescription medicines before taking Darif Tablet to avoid unwanted effects.

Dry mouth is the most common side effects of Darif Tablet , so you can drink plenty of fluids or water, suck hard candy or ice chips, chew (sugarless) gum, or use a saliva substitute. However, if you are a kidney patient before taking any fluid or electrolytes, it is better to consult a doctor.

The common side effect of the Darif Tablet is Diarrhea (a condition where you have loose, watery stools or bowel movements). Please do not panic about it. Usually, it vanishes over time as the body adjusts to the medication. If your loose motions persist longer, consult a doctor for personalized advice and management.

Edema is not a common side effect of the Darif Tablet . In rare instances, it may be experienced by some individuals. If you experience any unusual symptoms or side effects, it's important to consult your doctor for personalized advice and management.

The most common side effects of the Darif Tablet include dry mouth, constipation, nausea, blurred vision, indigestion, and headache. These side effects are usually mild and temporary and resolve as your body adjusts to the medication. However, if any side effects persist or worsen, it's essential to consult your doctor for proper guidance and care.

Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,INDIA
Other Info - DAR0021

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:49 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/food-interactions/darifenacin.html
  2. https://patient.info/medicine/darifenacin-tablets-emselex
  3. https://www.medicines.org.uk/emc/medicine/28307#gref
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