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Composition

DOCETAXEL-120MG

Manufacturer/Marketer

Fresenius Kabi India Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About DAXOTEL 120MG INJECTION 3ML

DAXOTEL 120MG INJECTION 3ML belongs to the class of 'anti-neoplastic/anti-cancer drugs', primarily used as a chemotherapy drug to treat cancers. It is effectively used in breast, lung, prostate, stomach, head/neck cancers. Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues.

DAXOTEL 120MG INJECTION 3ML contains Docetaxel, which belongs to the anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent, i.e., it prevents the cancer cells from rapidly dividing and spreading.

DAXOTEL 120MG INJECTION 3ML will be administered by a healthcare professional. Your doctor will decide the dosage depending on your medical condition. The common side effects of DAXOTEL 120MG INJECTION 3ML include pain/swelling at the injection site, headache, fatigue, dizziness, drowsiness, constipation, loss of appetite, indigestion, tearing of the eyes, nausea, vomiting, diarrhoea, insomnia (sleeplessness), fever (please inform your doctor if you have fever), muscle aches, and breathlessness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Do not use or stop this medicine if the doctor did not advise you. Before starting DAXOTEL 120MG INJECTION 3ML, let your doctor know if you have any allergic reactions, medical history of liver or kidney diseases, heart diseases, blood pressure problems, fits, lung disorders, weak immune system, anemia, low white blood cell count, vision problems, and are receiving chemotherapy. DAXOTEL 120MG INJECTION 3ML is not indicated for use in pregnant and breastfeeding women. DAXOTEL 120MG INJECTION 3ML may make you feel dizzy and drowsy, hence do not drive or operate machinery. It is not recommended to consume alcohol along with DAXOTEL 120MG INJECTION 3ML. DAXOTEL 120MG INJECTION 3ML is not recommended for children below two years of age.

Uses of DAXOTEL 120MG INJECTION 3ML

Treatment of Cancer

Medicinal Benefits

DAXOTEL 120MG INJECTION 3ML contains Docetaxel that belongs to the family of anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent and prevents cancer cells from rapidly dividing and spreading. Docetaxel may be used alone or in combination with other chemotherapy drugs to treat breast cancer that has spread to the tissues and lymph nodes (locally advanced breast cancer) and other parts (secondary breast cancer). It is also used in prostate cancer that does not respond to hormone treatment. It is further being investigated to treat small cell lung, ovarian, bladder, and pancreatic cancers.

Side Effects of DAXOTEL 120MG INJECTION 3ML

  • Pain/swelling at the injection site
  • Headache
  • Fatigue
  • Dizziness
  • Drowsiness
  • Constipation
  • Loss of appetite
  • Indigestion
  • Tearing of the eyes
  • Nausea
  • Vomiting
  • Diarrhoea
  • Insomnia (sleeplessness)
  • Fever (please inform your doctor if you have fever)
  • Muscle aches
  • Breathlessness

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Inform your doctor if you have any allergic reactions to DAXOTEL 120MG INJECTION 3ML or other medications. Before starting DAXOTEL 120MG INJECTION 3ML, let your doctor know if you have any medical history of allergic reactions, non-small cell lung cancer, liver or kidney diseases, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. DAXOTEL 120MG INJECTION 3ML can affect the unborn baby when used in pregnancy. It may also have harmful effects on the breastfed infant when used by a lactating mother. Hence, DAXOTEL 120MG INJECTION 3ML is not indicated in pregnancy and breastfeeding women. If you are using DAXOTEL 120MG INJECTION 3ML, use reliable contraception forms to prevent pregnancy during the course. DAXOTEL 120MG INJECTION 3ML can make you feel dizzy and drowsy, thus affecting your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused. Avoid alcohol consumption while being treated with DAXOTEL 120MG INJECTION 3ML. DAXOTEL 120MG INJECTION 3ML is not recommended for patients younger than 18 years of age.

Therapeutic Class

ANTINEOPLASTIC

Drug Interactions

Drug-Drug Interaction: DAXOTEL 120MG INJECTION 3ML may interact with antibiotics (itraconazole, erythromycin, rifabutin, metronidazole, tinidazole), HIV drugs (ritonavir), drugs to treat chronic alcoholism (disulfiram), opioid medicines (codeine, hydrocodone), muscle relaxants (carisoprodol, cyclobenzaprine), and anti-allergic medicines (cetirizine, diphenhydramine).

Drug-Food Interaction: Grapefruit and its juice may interact with DAXOTEL 120MG INJECTION 3ML. Also, avoid alcohol consumption.

Drug-Disease Interaction: DAXOTEL 120MG INJECTION 3ML should be used with caution in cases of allergic reactions, non-small cell lung cancer, liver or kidney diseases, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems.

Drug-Drug Interactions Checker List

  • ITRACONAZOLE
  • ERYTHROMYCIN
  • RIFABUTIN
  • METRONIDAZOLE
  • TINIDAZOLE
  • RITONAVIR
  • DISULFIRAM
  • CODEINE
  • HYDROCODONE
  • CARISOPRODOL
  • CYCLOBENZAPRINE
  • CETIRIZINE
  • DIPHENHYDRAMINE

Diet & Lifestyle Advise

  • Maintain a fiber-rich diet and include healthy carbohydrates from fruits, vegetables, and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli, and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Include whole grains, legumes, and follow a plant-based diet. Limiting dietary fats is advised during the breast cancer phase. Instead, include healthy fats, such as olive oil, avocado, nuts, seeds, and fatty fish
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk, and dairy products.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

Habit Forming

No

What if I have taken an overdose of DAXOTEL 120MG INJECTION 3ML

The overdose of DAXOTEL 120MG INJECTION 3ML is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with DAXOTEL 120MG INJECTION 3ML, please inform your doctor immediately.

Special Advise

  • Your doctor may advise regular physical exams and mammograms to rule out the possibility of breast cancer.
  • Self-examine your breasts to check for any lumps monthly.
  • Your doctor may also advise liver function tests to monitor your liver health.
  • Your doctor may advise blood tests and regular examinations of the prostate.

Disease/Condition Glossary

Cancer: It is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Cancer growth can be prevented by chemotherapy (by strong antibiotics), radiation, and stem cell therapy.

Breast cancer:  It is a type of cancer that develops in breast cells stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue, or the fibrous connective tissue within the breast. Symptoms include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size, or appearance of the breast, and a lump or swelling under the arm. 

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Alcohol

Unsafe

It is unsafe to consume alcohol while using DAXOTEL 120MG INJECTION 3ML since it may cause increased dizziness and drowsiness. Please consult your doctor for more information.

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Pregnancy

Unsafe

It is unsafe to use DAXOTEL 120MG INJECTION 3ML in pregnancy and can have harmful effects on the unborn baby. Use reliable forms of contraception to prevent pregnancy while using DAXOTEL 120MG INJECTION 3ML.

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Breast Feeding

Unsafe

DAXOTEL 120MG INJECTION 3ML is not recommended during breastfeeding since it may be unsafe for the breastfed infant. Please seek medical advice if you are a nursing mother before starting DAXOTEL 120MG INJECTION 3ML.

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Driving

Unsafe

DAXOTEL 120MG INJECTION 3ML causes dizziness and drowsiness that may affect your ability to drive. Do not drive or operate machinery if you experience unmanageable side effects with DAXOTEL 120MG INJECTION 3ML.

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Liver

Caution

Please let your doctor know if you have any history of liver diseases or hepatic impairment. Before being treated with DAXOTEL 120MG INJECTION 3ML, your doctor may advise you of blood tests to check your liver functioning.

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Kidney

Caution

Please let your doctor know if you have any history of kidney diseases before starting DAXOTEL 120MG INJECTION 3ML.

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Children

Unsafe

Safety and efficacy of DAXOTEL 120MG INJECTION 3ML have not been established in patients younger than 18 years.

Country of origin

India

Manufacturer/Marketer address

Fresenius Kabi AG? , Else-Kröner-Straße 1 ? , 61352 Bad Homburg , Germany
Other Info - DAX0001

FAQs

DAXOTEL 120MG INJECTION 3ML belongs to the class of 'anti-neoplastic/anti-cancer drugs', primarily used as a chemotherapy drug to treat cancers. It is effectively used in breast, lung, prostate, stomach, head/neck cancers.
DAXOTEL 120MG INJECTION 3ML contains Docetaxel, an anti-neoplastic agent. It prevents the cancer cells from rapidly dividing and spreading, thus slowing down their growth.
DAXOTEL 120MG INJECTION 3ML should be used with caution and under doctor's supervision only if you have any medical history of any allergic reactions, liver or kidney diseases, non-small cell lung cancer, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions (excess fluid around lungs), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. Let your doctor know if you have any other medical concerns before using DAXOTEL 120MG INJECTION 3ML.
During treatment with DAXOTEL 120MG INJECTION 3ML, it is essential to look for any signs of swelling (fluid retention/oedema), dizziness/fainting, difficulty in breathing, irregular heartbeat, swelling, pain and tenderness in the abdomen region, blood in stools, skin rashes, easy bleeding or bruising, sores in the mouth or throat or symptoms of infection like fever and sore throat. If you further notice any symptoms that are not manageable or unusual, please seek prompt medical attention.
It is advised to consult your doctor before undergoing any vaccination and take advice accordingly. Also, please avoid contact with people who have recently been vaccinated with the oral polio vaccine.
DAXOTEL 120MG INJECTION 3ML might cause serious allergic reactions and fluid retention if you had previously experienced allergic reactions with paclitaxel and cabazitaxel. These medicines contain polysorbate 80, an excipient. If you had any allergic reactions with medicines containing polysorbate 80, DAXOTEL 120MG INJECTION 3ML is not recommended. Please consult your doctor for more information.
DAXOTEL 120MG INJECTION 3ML is administered through an intravenous (IV) infusion. A healthcare professional usually gives it in a medical facility.
DAXOTEL 120MG INJECTION 3ML may cause weight loss due to common side effects such as loss of appetite, nausea, vomiting, diarrhoea, and fatigue. But, in rare cases, some patients may experience fluid retention or increased hunger, which can lead to weight gain. Consult your doctor or pharmacist for personalized guidance if you have concerns about weight changes.
The duration of DAXOTEL 120MG INJECTION 3ML treatment varies depending on the type of your cancer, dose of DAXOTEL 120MG INJECTION 3ML, and your response to therapy. Typically, it is administered once every 3 weeks. Your doctor will determine the total length of treatment for you based on your specific situation.
No, it is advisable not to drink alcohol while taking DAXOTEL 120MG INJECTION 3ML. Drinking alcohol during treatment may cause increased dizziness and drowsiness.
No, DAXOTEL 120MG INJECTION 3ML is not available in pill form. It is available in two primary dosage forms: injection and powder for injection.
Before administering DAXOTEL 120MG INJECTION 3ML, certain blood tests are required to ensure safe administration. These tests include a Complete Blood Count (CBC) to check blood cell counts, blood urea nitrogen (BUN) and creatinine levels to assess kidney function, liver function tests (LFTs) to evaluate liver health, and electrolyte level checks. Additionally, other tests may be required depending on individual patient needs and medical history. These blood tests help healthcare providers assess kidney and liver function and other vital parameters to ensure that DAXOTEL 120MG INJECTION 3ML can be administered safely and effectively. Your healthcare provider will determine the necessary blood tests and monitoring requirements.
Hair loss caused by DAXOTEL 120MG INJECTION 3ML is often reversible. While DAXOTEL 120MG INJECTION 3ML can cause hair thinning or loss, hair growth returns once treatment is stopped. However, in some cases, hair loss may be permanent. Consult your healthcare provider for guidance and support if you're concerned about hair loss.
Dexamethasone is used with DAXOTEL 120MG INJECTION 3ML to avoid toxicities.
DAXOTEL 120MG INJECTION 3ML is a chemotherapy medication that belongs to the class of drugs known as anti-neoplastic/anticancer drugs. It is a cytotoxic agent that prevents the cancer cells from rapidly dividing and spreading.
DAXOTEL 120MG INJECTION 3ML causes dizziness and drowsiness that may affect your ability to drive. So, do not drive or operate machinery if you experience these.
The common side effects of DAXOTEL 120MG INJECTION 3ML may include vomiting, constipation, changes in taste, extreme tiredness, muscle, joint, or bone pain, hair loss, nail changes, increased eye tearing, sores in the mouth and throat, and redness, dryness, or swelling at the injection site. However, these symptoms usually diminish as your body adjusts to the medication. If these symptoms worsen, please consult a doctor for relief.
DAXOTEL 120MG INJECTION 3ML is generally considered safe when following your doctor's advice. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.
DAXOTEL 120MG INJECTION 3ML contains Docetaxel, which belongs to the anticancer drugs.
Safety and efficacy of DAXOTEL 120MG INJECTION 3ML have not been established in patients younger than 18 years.

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