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  3. Decima 50 mg Injection 1's

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Decima 50 mg Injection 1's, Pack of 1 INJECTION
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Decima 50 mg Injection used to treat myelodysplastic syndrome. It contains Decitabine, which works by helping the bone marrow produce normal blood cells and kills abnormal cells in the bone marrow. The most common adverse reactions of Decima 50 mg Injection are injection site reactions, excessive tiredness, headache, dizziness, confusion, fast heartbeat, difficulty falling asleep or staying asleep, weakness, shortness of breath, nausea, constipation, diarrhoea, vomiting, heartburn, chest discomfort and swelling of the hands, feet, ankles, lower legs, or stomach.

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Composition :

DECITABINE-50MG

Manufacturer/Marketer :

Getwell Life Sciences India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Decima 50 mg Injection

Decima 50 mg Injection belongs to the group of medicines called hypomethylation agents used to treat myelodysplastic syndrome. A myelodysplastic syndrome is a group of malignancies known as myelodysplastic syndromes that occur when immature blood cells in the bone marrow do not mature or turn into healthy blood cells.

Decima 50 mg Injection contains ‘Decitabine’, which works by helping the bone marrow produce normal blood cells and kills abnormal cells in the bone marrow.

Decitabine should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer chemotherapeutic agents. Decitabine should usually be given for at least four cycles but may be continued if your doctor decides you will benefit from additional treatment. The most common adverse reactions of Decima 50 mg Injection are injection site reactions, excessive tiredness, headache, dizziness, confusion, fast heartbeat, difficulty falling asleep or staying asleep, weakness, shortness of breath, nausea, constipation, diarrhoea, vomiting, heartburn, chest discomfort and swelling of the hands, feet, ankles, lower legs, or stomach. Talk with your doctor if you experience any of these side effects persistently.

Decitabine may harm your fetus. Avoid taking Decima 50 mg Injection if you are pregnant or breastfeeding. You or your partner should not become pregnant while you are using decitabine. It would be best if you used birth control to prevent pregnancy in yourself or your partner during your treatment with decitabine and for two months afterwards. Call your doctor if you or your partner becomes pregnant while using decitabine. If you are breastfeeding. Do not breastfeed while you take this drug and for two weeks after your last dose. Decima 50 mg Injection may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if alert. Decima 50 mg Injection is not recommended for children below 18 years as safety and effectiveness have not been established. Inform your doctor about your health condition and medications before taking Decima 50 mg Injection to rule out interactions.

Uses of Decima 50 mg Injection

Decima 50 mg Injection is used to treat blood and bone marrow disorders. The detailed uses of Decima 50 mg Injection are as follows:<br/>• Treats myelodysplastic syndrome (MDS): Decima 50 mg Injection helps manage a group of conditions where the bone marrow makes misshapen or insufficient healthy blood cells.<br/>• Promotes healthy blood cell production: Decima 50 mg Injection aids the bone marrow in producing normal blood cells.<br/>• Targets abnormal bone marrow cells: Decima 50 mg Injection works by destroying abnormal cells in the bone marrow to improve overall blood health.<br/>

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Directions for Use

• Typically, Decima 50 mg Injection is given every 8 hours for 3 days, with cycles repeated every 6 weeks, or as recommended by your doctor.• Decima 50 mg Injection will be administered by a doctor or nurse in a healthcare facility.• Do not self-administer.

Medicinal Benefits

Decima 50 mg Injection belongs to the group of medicines called hypomethylation agents used to treat myelodysplastic syndrome. Decima 50 mg Injection contains ‘Decitabine’, which works by helping the bone marrow produce normal blood cells and kills abnormal cells in the bone marrow. On the other hand, it can treat blood cancer, known as acute myeloid leukemia (AML).

How Decima 50 mg Injection Works

Decima 50 mg Injection contains Decitabine, which works by helping the bone marrow produce normal blood cells and kills abnormal cells in the bone marrow.

Storage

• Store in a cool and dry place away from sunlight.• Keep Decima 50 mg Injection out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Decima 50 mg Injection
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.

What if I have taken an overdose of Decima 50 mg Injection

Since Decima 50 mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Decima 50 mg Injection may cause unusual bleeding or bruising, sore throat, fever, chills, cough, or other signs of infection.

Drug Warnings

Before taking the Decima 50 mg Injection, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Before and during your therapy, your doctor will prescribe laboratory testing on a regular basis. You may have a higher risk of infection. Hands must be washed frequently. Avoid contact with those who have illnesses, colds, or the flu. You may bleed more easily. Take precautions to avoid injury. Do not skip any scheduled dose or take other medications unless prescribed by the doctor.

Drug-Drug Interactions

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DecitabineLeflunomide
Severe

Drug-Drug Interactions

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DecitabineLeflunomide
Severe
How does the drug interact with Decima 50 mg Injection:
Combining Decima 50 mg Injection with Leflunomide can increase the risk of negative side effects.

How to manage the interaction:
Taking Leflunomide with Decima 50 mg Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact your doctor right away: infection, complications, fever, chills, diarrhea, sore throat, muscle aches, trouble breathing, losing weight, or pain/burning when you pee. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Decima 50 mg Injection Substitute

Substitutes safety advice
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while on treatment with Decima 50 mg Injection as it might cause increased dizziness.

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Pregnancy

Unsafe

Decima 50 mg Injection should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

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Breast Feeding

Unsafe

Decima 50 mg Injection should not be used in breastfeeding. Discuss with your doctor if you have any concerns.

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Driving

Unsafe

Decima 50 mg Injection may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Inform your doctor before receiving the Decima 50 mg Injection if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving the Decima 50 mg Injection if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Decima 50 mg Injection is not recommended for children below 18 years as the safety and effectiveness have not been established.

FAQs

Decima 50 mg Injection is used to treat Myelodysplastic syndrome.

Decima 50 mg Injection contains Decitabine, which works by helping the bone marrow produce normal blood cells and by killing abnormal cells in the bone marrow.

Decitabine therapy should usually be given as a three- or five-day regimen based on your medical condition and response to the treatment. Do not stop taking Decima 50 mg Injection on your own. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Decima 50 mg Injection.

Decima 50 mg Injection can be used to treat blood cancer known as acute myeloid leukemia (AML).

Decima 50 mg Injection therapy may cause a change in skin colour or pale skin or red spots on the skin. Consult your doctor immediately if you notice these symptoms persistently.

Decima 50 mg Injection might cause neutropenia (low white blood cells) and thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Decima 50 mg Injection.

Decitabine may raise blood sugar. If you have high blood sugar (diabetes), talk with your doctor.

No, Decima 50 mg Injection is not a vesicant. It is an anti-cancer drug that is not known to cause severe tissue damage when it leaks from the injection site into surrounding tissues. It belongs to the group of medications called hypo methylation agents used to treat myelodysplastic syndrome.

Decima 50 mg Injection effectively treats myelodysplastic syndrome, a group of disorders in which the bone marrow produces misshapen blood cells and insufficient healthy blood cells. It works by promoting the production of normal blood cells in the bone marrow and eliminating abnormal cells. However, the degree of effectiveness varies among individuals based on their medical condition.

Yes, Decima 50 mg Injection may cause hair loss as a common side effect. To cope with hair loss, manage stress, maintain a healthy diet, avoid harsh hair treatments, use gentle hair care products, and consider medical treatments or therapies as advised by a doctor.

Decima 50 mg Injection is administered through an intravenous route (into a vein) slowly over 3 hours by the doctor or nurse. It is usually administered every 8 hours for 3 days depending on the prescribed dose and treatment plan.

The side effects of Decima 50 mg Injection include vomiting, nausea, injection site reactions, excessive tiredness, headache, dizziness, confusion, fast heartbeat, difficulty falling asleep or staying asleep, weakness, shortness of breath, constipation, diarrhoea, heartburn, chest discomfort and swelling of the hands, feet, ankles, lower legs, or stomach. Consult the doctor if any of these side effects persist or worsen.

Country of origin

INDIA

Manufacturer/Marketer address

305, Bakshi House, 40-41, Nehru Place ., New Delhi- 110 017
Other Info - DEC0204

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:04 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://aarkpharma.com/product/xalibo-decitabine-price-in-india/
  2. https://go.drugbank.com/drugs/DB01262
  3. https://medlineplus.gov/druginfo/meds/a608009.html
  4. https://reference.medscape.com/drug/dacogen-decitabine-342091
  5. https://www.sciencedirect.com/topics/medicine-and-dentistry/decitabine
  6. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021790s021lbl.pdf
  7. https://www.mskcc.org/cancer-care/patient-education/medications/adult/decitabine?msk_tools_print=pdf
  8. https://www.drugs.com/drug-interactions/decitabine-index.html?filter=3

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